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The map label for this gene is pheA [H]

Identifier: 13474585

GI number: 13474585

Start: 4411378

End: 4412241

Strand: Direct

Name: pheA [H]

Synonym: mlr5498

Alternate gene names: 13474585

Gene position: 4411378-4412241 (Clockwise)

Preceding gene: 13474584

Following gene: 13474589

Centisome position: 62.7

GC content: 62.96

Gene sequence:

>864_bases
ATGCCTGAAAAGACCAACAGAATATCCTTCCAGGGCGAGCCGGGCGCCAATTCCGACACCGCCTGCCGCAACGTCTATCC
CTCGATGGAGCCGTTGCCGTGCCCGACCTTCGAGGATGCGTTCAACGCGGTCGAGACCGGCAAGGCCGACCTCGCCATGA
TCCCGATCGAGAACACCATCGCCGGACGCGTCGCCGACATCCACCACCTGCTGCCGGAATCGCGGATGCACATCGTCGGT
GAATATTTCCTGCCCATCCATTTCCAGCTGATGGTGCTGCCCGGCGTCAAGCGCGACGAGATCAAGACCGTGCACAGCCA
TATCCATGCGCTTGGCCAGTGCCGCAAATACATCCGCAAGAACGGCTGGAAGGCGGTCGTCGCCGGCGACACGGCGGGTG
CGGCCAAGATGATCTCCGAGGTCAAGGACCGCACCATGGCCGCGCTGTCGCCGGCGCTGGCCGCGACGCTCTACGGGCTC
GATATCATCGAGGAAAATGTCGAGGACACCGATTCCAACGTCACCCGCTTCGTCGTCCTGACCAAGAGCAAGCAATGGGC
CGAACGGCCGTCACCGGACGTCAAGATGATGACCACCTTCATCTTCCGCGTCCGCAACGTGCCGGCCGCGCTCTACAAGG
CCATGGGCGGTTTCGCCACCAACGGCATCAACATGACCAAGCTGGAGAGCTACCAGCTCGGCGCGTTCACCGCGACGCTG
TTCTACGCCGACATCGAGGGCCATCCCGACGATCCGCTGGTCAAGCTGGCGCTGGACGAGTTGCGCTTCTTCTCCCGCGA
GGTGCGGATTCTCGGCGTCTATCCGGCCAGCGAGTCGCGCGAGCAGTGGAAGGTGGCTGACTAA

Upstream 100 bases:

>100_bases
CGCTTGGCGTCGACACGCCGCAAGACCTTGAGCGCGCCCGAACCATTCTTTCCAACTGAGAAATCCCTTCGACACCGTGA
CGTGAATCGAGACCTGGCCC

Downstream 100 bases:

>100_bases
ACGACCGAGCCCAGCGGCACATAGTCGATCTCGAGAAACTTCTCGACCTCCGGCACCCAGCGGTCGCGCACGAAGGCGAC
ATGGTCGGGGTGGTCGTTGT

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MPEKTNRISFQGEPGANSDTACRNVYPSMEPLPCPTFEDAFNAVETGKADLAMIPIENTIAGRVADIHHLLPESRMHIVG
EYFLPIHFQLMVLPGVKRDEIKTVHSHIHALGQCRKYIRKNGWKAVVAGDTAGAAKMISEVKDRTMAALSPALAATLYGL
DIIEENVEDTDSNVTRFVVLTKSKQWAERPSPDVKMMTTFIFRVRNVPAALYKAMGGFATNGINMTKLESYQLGAFTATL
FYADIEGHPDDPLVKLALDELRFFSREVRILGVYPASESREQWKVAD

Sequences:

>Translated_287_residues
MPEKTNRISFQGEPGANSDTACRNVYPSMEPLPCPTFEDAFNAVETGKADLAMIPIENTIAGRVADIHHLLPESRMHIVG
EYFLPIHFQLMVLPGVKRDEIKTVHSHIHALGQCRKYIRKNGWKAVVAGDTAGAAKMISEVKDRTMAALSPALAATLYGL
DIIEENVEDTDSNVTRFVVLTKSKQWAERPSPDVKMMTTFIFRVRNVPAALYKAMGGFATNGINMTKLESYQLGAFTATL
FYADIEGHPDDPLVKLALDELRFFSREVRILGVYPASESREQWKVAD
>Mature_286_residues
PEKTNRISFQGEPGANSDTACRNVYPSMEPLPCPTFEDAFNAVETGKADLAMIPIENTIAGRVADIHHLLPESRMHIVGE
YFLPIHFQLMVLPGVKRDEIKTVHSHIHALGQCRKYIRKNGWKAVVAGDTAGAAKMISEVKDRTMAALSPALAATLYGLD
IIEENVEDTDSNVTRFVVLTKSKQWAERPSPDVKMMTTFIFRVRNVPAALYKAMGGFATNGINMTKLESYQLGAFTATLF
YADIEGHPDDPLVKLALDELRFFSREVRILGVYPASESREQWKVAD

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=276, Percent_Identity=34.0579710144928, Blast_Score=142, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 31930; Mature: 31799

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00857 PREPHENATE_DEHYDR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEKTNRISFQGEPGANSDTACRNVYPSMEPLPCPTFEDAFNAVETGKADLAMIPIENTI
CCCCCCEEEECCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCHH
AGRVADIHHLLPESRMHIVGEYFLPIHFQLMVLPGVKRDEIKTVHSHIHALGQCRKYIRK
HHHHHHHHHHCCHHHHHHHHHHECCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHC
NGWKAVVAGDTAGAAKMISEVKDRTMAALSPALAATLYGLDIIEENVEDTDSNVTRFVVL
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEE
TKSKQWAERPSPDVKMMTTFIFRVRNVPAALYKAMGGFATNGINMTKLESYQLGAFTATL
ECCHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEECCEECCEEEEEE
FYADIEGHPDDPLVKLALDELRFFSREVRILGVYPASESREQWKVAD
EEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
PEKTNRISFQGEPGANSDTACRNVYPSMEPLPCPTFEDAFNAVETGKADLAMIPIENTI
CCCCCEEEECCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCHH
AGRVADIHHLLPESRMHIVGEYFLPIHFQLMVLPGVKRDEIKTVHSHIHALGQCRKYIRK
HHHHHHHHHHCCHHHHHHHHHHECCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHC
NGWKAVVAGDTAGAAKMISEVKDRTMAALSPALAATLYGLDIIEENVEDTDSNVTRFVVL
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEE
TKSKQWAERPSPDVKMMTTFIFRVRNVPAALYKAMGGFATNGINMTKLESYQLGAFTATL
ECCHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEECCEECCEEEEEE
FYADIEGHPDDPLVKLALDELRFFSREVRILGVYPASESREQWKVAD
EEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1512561; 1444388 [H]