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The map label for this gene is dppA [H]

Identifier: 13474516

GI number: 13474516

Start: 4333120

End: 4334718

Strand: Direct

Name: dppA [H]

Synonym: mlr5416

Alternate gene names: 13474516

Gene position: 4333120-4334718 (Clockwise)

Preceding gene: 13474513

Following gene: 13474517

Centisome position: 61.58

GC content: 59.79

Gene sequence:

>1599_bases
ATGAAAAAGAAACTCGCTTTTGCGGCCGCGTTGCTGGCCGCAAGCGTCCTGGGCGGCATGGCCAATGCAAAGACGCTCGT
CTATTGCTCGGAAGCATCGCCTGCCAATTTTGATCCGGGTACCACGACCGGCGGCAACGACTTCGATGCCTCGTCGCGCA
CCGTCTATTCGCGCCTGGTCGAGTTCAAGCATGGCGGCACCGAGGTCGAGCCCGGCCTTGCCGACAAGTGGGACATCTCG
GACGACGGCCTGGTCTATACTTTCCACCTGCATCCGGGCGTGAAGTTCCAGACCACCGACTATTTCAAGCCGACGCGCGA
CCTGAATGCCGATGACGTCGTCTTCTCCTTCGATCGCCAGTTCAACAAACAGAATCCCTGGAACGGCGACAAGTATCTGC
CGAACCTGACCTGGGACTATTACACCGGCATGGACATGCCGAAATATGTCGCCAAGTGGGAGAAGGTCGACGATCTGACC
GTCAAGCTGACGCTGACCGAGCCGAACGCGCCGATGCTGGCTAACCTCGGCATGGACTTTGCTTCGATCGTGTCGAAGGA
ATATGCCGACCAGCTGGCGAAGGACGGCAAGATGGCCGACTTCTCGACCAAGCCGATCGGCACCGGCCCGTTCCAGTTCG
TCGACTACCAGCTGGATTCGGTCATCCGCTATGCGGCCAACCCAGACTACTTCAAGGGCAAGGAGAAGATCGACGATCTC
GTCTTCGCCATCACGCCTGACGCCACCGCCCGCACCCAGAAAGTGCTTGCCGGCGAATGCGACATCGCGCCCTATCCGAA
CCCGGCCGACATCGCCACCATTAAGGCCAATAAGGACGTGACCCTGATGGATCAGGCCGGCCTGAACATCGGCTATATGA
GCTATAACACCACCATCCCGCCGCTCGACAAGCCTGAGGTGCGCCATGCGCTCAACCAGGCGATCGACCGGCAAGCGTTG
ATCAAGTCGCTGTTCCAGGATGCAGGCGCCACGCCCGCTGAAAACCTGATCCCGCCGACCATGTGGTCGTGGAACAAGGA
TGTGAAGACCGACGCCTACAATCCGGAAGCGGCCAAGAAGGTACTTGAGGCTGCCGGGCTGAAGGAAATCCAGCTCTGGG
CATCCGACCGCGTTCGTCCCTACAATCCGAACTTCCAGCGCGCCGCCGAACTGATCCAGGCCGACTGGGCCAAGGTCGGC
GTCAAGGCGGAGATCGTCAACTACGAGTGGACCAAGTATCGCTCGGAAGGCAAGAAGAAGGACCGTCCAGGCGCCTTCCA
GATCGGCTGGACCGGCGACAATGGCGATCCGGACAACTTCTTCGCCACCCTGTTCGCCTGCTCGGCCATCGGCGTGTCGA
ACTACTCGAGCTGGTGCGACAAGGACTTCGAGGATCTGATTCAGAAGGCCAAGAAGACCAGCGACCAGGCCGAGCGCTCC
AAGCTCTATGAGCAGGCGCAGGTGATCTTCGCCAAGGAAGCGCCCGCCTTCCTGCTGGTCCACAGTCAAGTCTATGCGGT
CGTGCGCAACAATGTCAGCGGTTTCAAGATGGATCCGCTCGGCATTCACCGCTTCGACGGCGTTGACAAGGCCGAATAA

Upstream 100 bases:

>100_bases
GGGTAAGCAAACGGGGTGTTCCAAAGCCGGAAAAACGGTGCTTATATGCGCGCTTCGCGAGCCTGCTAGAGGGGCTTGGA
AGAACATCAGGGAGTGCTCA

Downstream 100 bases:

>100_bases
GACTATAGAGCGGGGCGGCGCAATGAAGCGCCGCCCCCCTACATCATGCTAAAATATATCCTCCACCGAATTGCACTTTT
GATCCCGACGCTGGTCGGCA

Product: ABC transporter, periplasmic binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MKKKLAFAAALLAASVLGGMANAKTLVYCSEASPANFDPGTTTGGNDFDASSRTVYSRLVEFKHGGTEVEPGLADKWDIS
DDGLVYTFHLHPGVKFQTTDYFKPTRDLNADDVVFSFDRQFNKQNPWNGDKYLPNLTWDYYTGMDMPKYVAKWEKVDDLT
VKLTLTEPNAPMLANLGMDFASIVSKEYADQLAKDGKMADFSTKPIGTGPFQFVDYQLDSVIRYAANPDYFKGKEKIDDL
VFAITPDATARTQKVLAGECDIAPYPNPADIATIKANKDVTLMDQAGLNIGYMSYNTTIPPLDKPEVRHALNQAIDRQAL
IKSLFQDAGATPAENLIPPTMWSWNKDVKTDAYNPEAAKKVLEAAGLKEIQLWASDRVRPYNPNFQRAAELIQADWAKVG
VKAEIVNYEWTKYRSEGKKKDRPGAFQIGWTGDNGDPDNFFATLFACSAIGVSNYSSWCDKDFEDLIQKAKKTSDQAERS
KLYEQAQVIFAKEAPAFLLVHSQVYAVVRNNVSGFKMDPLGIHRFDGVDKAE

Sequences:

>Translated_532_residues
MKKKLAFAAALLAASVLGGMANAKTLVYCSEASPANFDPGTTTGGNDFDASSRTVYSRLVEFKHGGTEVEPGLADKWDIS
DDGLVYTFHLHPGVKFQTTDYFKPTRDLNADDVVFSFDRQFNKQNPWNGDKYLPNLTWDYYTGMDMPKYVAKWEKVDDLT
VKLTLTEPNAPMLANLGMDFASIVSKEYADQLAKDGKMADFSTKPIGTGPFQFVDYQLDSVIRYAANPDYFKGKEKIDDL
VFAITPDATARTQKVLAGECDIAPYPNPADIATIKANKDVTLMDQAGLNIGYMSYNTTIPPLDKPEVRHALNQAIDRQAL
IKSLFQDAGATPAENLIPPTMWSWNKDVKTDAYNPEAAKKVLEAAGLKEIQLWASDRVRPYNPNFQRAAELIQADWAKVG
VKAEIVNYEWTKYRSEGKKKDRPGAFQIGWTGDNGDPDNFFATLFACSAIGVSNYSSWCDKDFEDLIQKAKKTSDQAERS
KLYEQAQVIFAKEAPAFLLVHSQVYAVVRNNVSGFKMDPLGIHRFDGVDKAE
>Mature_532_residues
MKKKLAFAAALLAASVLGGMANAKTLVYCSEASPANFDPGTTTGGNDFDASSRTVYSRLVEFKHGGTEVEPGLADKWDIS
DDGLVYTFHLHPGVKFQTTDYFKPTRDLNADDVVFSFDRQFNKQNPWNGDKYLPNLTWDYYTGMDMPKYVAKWEKVDDLT
VKLTLTEPNAPMLANLGMDFASIVSKEYADQLAKDGKMADFSTKPIGTGPFQFVDYQLDSVIRYAANPDYFKGKEKIDDL
VFAITPDATARTQKVLAGECDIAPYPNPADIATIKANKDVTLMDQAGLNIGYMSYNTTIPPLDKPEVRHALNQAIDRQAL
IKSLFQDAGATPAENLIPPTMWSWNKDVKTDAYNPEAAKKVLEAAGLKEIQLWASDRVRPYNPNFQRAAELIQADWAKVG
VKAEIVNYEWTKYRSEGKKKDRPGAFQIGWTGDNGDPDNFFATLFACSAIGVSNYSSWCDKDFEDLIQKAKKTSDQAERS
KLYEQAQVIFAKEAPAFLLVHSQVYAVVRNNVSGFKMDPLGIHRFDGVDKAE

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=532, Percent_Identity=53.7593984962406, Blast_Score=564, Evalue=1e-162,
Organism=Escherichia coli, GI1787551, Length=510, Percent_Identity=34.3137254901961, Blast_Score=319, Evalue=2e-88,
Organism=Escherichia coli, GI1787052, Length=469, Percent_Identity=29.637526652452, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1787762, Length=542, Percent_Identity=25.4612546125461, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1789397, Length=527, Percent_Identity=23.5294117647059, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1787495, Length=562, Percent_Identity=23.3096085409253, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1789887, Length=489, Percent_Identity=23.3128834355828, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081878, Length=516, Percent_Identity=24.2248062015504, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59204; Mature: 59204

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKLAFAAALLAASVLGGMANAKTLVYCSEASPANFDPGTTTGGNDFDASSRTVYSRLV
CCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
EFKHGGTEVEPGLADKWDISDDGLVYTFHLHPGVKFQTTDYFKPTRDLNADDVVFSFDRQ
HHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEECCCCCCCCCCCCCCEEEEEHHH
FNKQNPWNGDKYLPNLTWDYYTGMDMPKYVAKWEKVDDLTVKLTLTEPNAPMLANLGMDF
CCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHCCCCEEEEEEEECCCCCEEECCCCHH
ASIVSKEYADQLAKDGKMADFSTKPIGTGPFQFVDYQLDSVIRYAANPDYFKGKEKIDDL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCE
VFAITPDATARTQKVLAGECDIAPYPNPADIATIKANKDVTLMDQAGLNIGYMSYNTTIP
EEEECCCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCEEEEECCCCEEEEEEECCCCC
PLDKPEVRHALNQAIDRQALIKSLFQDAGATPAENLIPPTMWSWNKDVKTDAYNPEAAKK
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHH
VLEAAGLKEIQLWASDRVRPYNPNFQRAAELIQADWAKVGVKAEIVNYEWTKYRSEGKKK
HHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHCCCCC
DRPGAFQIGWTGDNGDPDNFFATLFACSAIGVSNYSSWCDKDFEDLIQKAKKTSDQAERS
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHHHHHHCCHHHHHH
KLYEQAQVIFAKEAPAFLLVHSQVYAVVRNNVSGFKMDPLGIHRFDGVDKAE
HHHHHHHEEEECCCCEEEEEHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKKLAFAAALLAASVLGGMANAKTLVYCSEASPANFDPGTTTGGNDFDASSRTVYSRLV
CCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
EFKHGGTEVEPGLADKWDISDDGLVYTFHLHPGVKFQTTDYFKPTRDLNADDVVFSFDRQ
HHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEECCCCCCCCCCCCCCEEEEEHHH
FNKQNPWNGDKYLPNLTWDYYTGMDMPKYVAKWEKVDDLTVKLTLTEPNAPMLANLGMDF
CCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHCCCCEEEEEEEECCCCCEEECCCCHH
ASIVSKEYADQLAKDGKMADFSTKPIGTGPFQFVDYQLDSVIRYAANPDYFKGKEKIDDL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCE
VFAITPDATARTQKVLAGECDIAPYPNPADIATIKANKDVTLMDQAGLNIGYMSYNTTIP
EEEECCCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCEEEEECCCCEEEEEEECCCCC
PLDKPEVRHALNQAIDRQALIKSLFQDAGATPAENLIPPTMWSWNKDVKTDAYNPEAAKK
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHH
VLEAAGLKEIQLWASDRVRPYNPNFQRAAELIQADWAKVGVKAEIVNYEWTKYRSEGKKK
HHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHCCCCC
DRPGAFQIGWTGDNGDPDNFFATLFACSAIGVSNYSSWCDKDFEDLIQKAKKTSDQAERS
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHHHHHHCCHHHHHH
KLYEQAQVIFAKEAPAFLLVHSQVYAVVRNNVSGFKMDPLGIHRFDGVDKAE
HHHHHHHEEEECCCCEEEEEHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]