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The map label for this gene is pntB [H]

Identifier: 13474323

GI number: 13474323

Start: 4117366

End: 4118763

Strand: Direct

Name: pntB [H]

Synonym: mlr5184

Alternate gene names: 13474323

Gene position: 4117366-4118763 (Clockwise)

Preceding gene: 13474322

Following gene: 13474329

Centisome position: 58.52

GC content: 64.45

Gene sequence:

>1398_bases
ATGAACGCCAACTTCGCGTCCTTCCTCTATCTCGTCTCCGGCGTCCTGTTCATCATGGCGCTGCGCGGCCTGTCGCATCC
GACCACCAGCCGCCAGGGCAATCTCTACGGCATGATCGGCATGGGCATCGCCATTGCCACCACGCTGGCGCTGGCAACCC
CGTCCGCGGGCCGCTTTGGCCTCATCGTGCTCGGCCTTGCCATTGGCGGCGGCGTCGGTGCCGTCACCGCGCGCCGCATC
GCCATGACCTCGATGCCGCAGCTGGTTGCCGCCTTCCATTCGCTGGTCGGCCTTGCCGCCGTCATGGTGGCGGCAGCCGC
CATCTACGCGCCGGAAAGCTTCGGCATCGGCACGGCGGGCGACATCCATGCCCAGGCGCTGATCGAGATGAGCCTCGGCG
TTGCCATCGGCGCCATCACCTTCACCGGCTCGGTCATCGCCTTCTTGAAGCTCGATGGCCGCATGTCCGGCAAGCCGATC
ATGCTCGGCGGCCGTCATTTCATCAACGCCGCCCTGGGCGTCGCGCTCATCGTGCTGATCGTGCTGCTGGTCACCACGGA
ATCGAAGCTGGTCTTCTGGCTGATCGTCGCCGCCTCTCTGGTGCTCGGCGTCCTCTTGATCATCCCGATCGGCGGCGCCG
ACATGCCGGTCGTCGTCTCGATGCTCAACTCCTATTCGGGCTGGGCAGCGGCCGCGCTTGGCTTCACGCTCGGCAATCTG
GCGCTGATCATCACCGGCGCGCTGGTCGGCTCGTCCGGCGCGATCCTGTCCTACATCATGTGCAAGGGCATGAACCGCTC
GTTCATCTCGGTCATCCTTGGCGGCTTCGGCGGTGAGACGGCGGCTGCGGCCGACGACGGCATCGAGCGCACAGTCAAGC
AGGGTTCGGCAGATGATGCCGCCTATCTGATGATGAACGCGCAGAAGGTCATCATCGTGCCAGGCTACGGCATGGCGGTC
GCCCAGGCGCAGCATGCGCTGCGCGAAATGGCCGACAAGCTCAAGGCCAACGGCGTCGACGTGAAATACGCCATCCACCC
GGTCGCCGGCCGCATGCCCGGCCATATGAACGTGCTCTTGGCCGAAGCCAACGTGCCCTATGACGAAGTGTTCGAGCTCG
AGGACATCAATTCGGAGTTCGCGCAGGCCGATGTCGCCTATGTCATCGGCGCCAACGACGTCACCAACCCGTCCGCGCGG
GACGATAAGAGCAGCCCCATCTATGGCATGCCGATCCTCGACGTCGACAAGGCGCGCACCTGCCTGTTCGTCAAGCGCTC
GCTCGGCTCCGGCTATGCCGGCATCGACAACACGCTGTTCTACAAGGACGGCACCATGATGCTGCTCGGCGACGCCAAGA
AGATGACAGAGGAAATCGTCAAGGCCATGGATCACTGA

Upstream 100 bases:

>100_bases
CTTCGTCGCGCTGATGCTGGTCTCGGTCAACATCTTCGGCGGCTTCCTCGTCACCCAGCGCATGCTGGCAATGTACAAGA
AGAAGGACAAGTAGAGCGCC

Downstream 100 bases:

>100_bases
TCCGGCCATAGGCGGAAATAGCAAAGAGCCCGGCCCAGGGGCCGGGCTCTTTCATTTTTGACGCAAGCCTAGGCTCAGCG
GCTGGTCAGGAAGACCGCTT

Product: nicotinamide nucleotide transhydrogenase, subunit beta

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MNANFASFLYLVSGVLFIMALRGLSHPTTSRQGNLYGMIGMGIAIATTLALATPSAGRFGLIVLGLAIGGGVGAVTARRI
AMTSMPQLVAAFHSLVGLAAVMVAAAAIYAPESFGIGTAGDIHAQALIEMSLGVAIGAITFTGSVIAFLKLDGRMSGKPI
MLGGRHFINAALGVALIVLIVLLVTTESKLVFWLIVAASLVLGVLLIIPIGGADMPVVVSMLNSYSGWAAAALGFTLGNL
ALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGETAAAADDGIERTVKQGSADDAAYLMMNAQKVIIVPGYGMAV
AQAQHALREMADKLKANGVDVKYAIHPVAGRMPGHMNVLLAEANVPYDEVFELEDINSEFAQADVAYVIGANDVTNPSAR
DDKSSPIYGMPILDVDKARTCLFVKRSLGSGYAGIDNTLFYKDGTMMLLGDAKKMTEEIVKAMDH

Sequences:

>Translated_465_residues
MNANFASFLYLVSGVLFIMALRGLSHPTTSRQGNLYGMIGMGIAIATTLALATPSAGRFGLIVLGLAIGGGVGAVTARRI
AMTSMPQLVAAFHSLVGLAAVMVAAAAIYAPESFGIGTAGDIHAQALIEMSLGVAIGAITFTGSVIAFLKLDGRMSGKPI
MLGGRHFINAALGVALIVLIVLLVTTESKLVFWLIVAASLVLGVLLIIPIGGADMPVVVSMLNSYSGWAAAALGFTLGNL
ALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGETAAAADDGIERTVKQGSADDAAYLMMNAQKVIIVPGYGMAV
AQAQHALREMADKLKANGVDVKYAIHPVAGRMPGHMNVLLAEANVPYDEVFELEDINSEFAQADVAYVIGANDVTNPSAR
DDKSSPIYGMPILDVDKARTCLFVKRSLGSGYAGIDNTLFYKDGTMMLLGDAKKMTEEIVKAMDH
>Mature_465_residues
MNANFASFLYLVSGVLFIMALRGLSHPTTSRQGNLYGMIGMGIAIATTLALATPSAGRFGLIVLGLAIGGGVGAVTARRI
AMTSMPQLVAAFHSLVGLAAVMVAAAAIYAPESFGIGTAGDIHAQALIEMSLGVAIGAITFTGSVIAFLKLDGRMSGKPI
MLGGRHFINAALGVALIVLIVLLVTTESKLVFWLIVAASLVLGVLLIIPIGGADMPVVVSMLNSYSGWAAAALGFTLGNL
ALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGETAAAADDGIERTVKQGSADDAAYLMMNAQKVIIVPGYGMAV
AQAQHALREMADKLKANGVDVKYAIHPVAGRMPGHMNVLLAEANVPYDEVFELEDINSEFAQADVAYVIGANDVTNPSAR
DDKSSPIYGMPILDVDKARTCLFVKRSLGSGYAGIDNTLFYKDGTMMLLGDAKKMTEEIVKAMDH

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=462, Percent_Identity=46.5367965367965, Blast_Score=374, Evalue=1e-104,
Organism=Homo sapiens, GI122939153, Length=462, Percent_Identity=46.5367965367965, Blast_Score=374, Evalue=1e-104,
Organism=Escherichia coli, GI1787886, Length=458, Percent_Identity=53.2751091703057, Blast_Score=463, Evalue=1e-132,
Organism=Caenorhabditis elegans, GI17550456, Length=460, Percent_Identity=45.6521739130435, Blast_Score=365, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 48297; Mature: 48297

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNANFASFLYLVSGVLFIMALRGLSHPTTSRQGNLYGMIGMGIAIATTLALATPSAGRFG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCHH
LIVLGLAIGGGVGAVTARRIAMTSMPQLVAAFHSLVGLAAVMVAAAAIYAPESFGIGTAG
HHEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
DIHAQALIEMSLGVAIGAITFTGSVIAFLKLDGRMSGKPIMLGGRHFINAALGVALIVLI
CHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHH
VLLVTTESKLVFWLIVAASLVLGVLLIIPIGGADMPVVVSMLNSYSGWAAAALGFTLGNL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
ALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGETAAAADDGIERTVKQGSADDA
HHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCC
AYLMMNAQKVIIVPGYGMAVAQAQHALREMADKLKANGVDVKYAIHPVAGRMPGHMNVLL
EEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEEE
AEANVPYDEVFELEDINSEFAQADVAYVIGANDVTNPSARDDKSSPIYGMPILDVDKART
EECCCCHHHHHHHHHCCHHHHHCCEEEEEECCCCCCCCCCCCCCCCEECCCCEECCCCHH
CLFVKRSLGSGYAGIDNTLFYKDGTMMLLGDAKKMTEEIVKAMDH
HHEEHHHCCCCCCCCCCEEEEECCCEEEECCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNANFASFLYLVSGVLFIMALRGLSHPTTSRQGNLYGMIGMGIAIATTLALATPSAGRFG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCHH
LIVLGLAIGGGVGAVTARRIAMTSMPQLVAAFHSLVGLAAVMVAAAAIYAPESFGIGTAG
HHEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
DIHAQALIEMSLGVAIGAITFTGSVIAFLKLDGRMSGKPIMLGGRHFINAALGVALIVLI
CHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHH
VLLVTTESKLVFWLIVAASLVLGVLLIIPIGGADMPVVVSMLNSYSGWAAAALGFTLGNL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
ALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGETAAAADDGIERTVKQGSADDA
HHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCC
AYLMMNAQKVIIVPGYGMAVAQAQHALREMADKLKANGVDVKYAIHPVAGRMPGHMNVLL
EEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEEE
AEANVPYDEVFELEDINSEFAQADVAYVIGANDVTNPSARDDKSSPIYGMPILDVDKART
EECCCCHHHHHHHHHCCHHHHHCCEEEEEECCCCCCCCCCCCCCCCEECCCCEECCCCHH
CLFVKRSLGSGYAGIDNTLFYKDGTMMLLGDAKKMTEEIVKAMDH
HHEEHHHCCCCCCCCCCEEEEECCCEEEECCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]