Click here to switch to the map view.

The map label for this gene is pntAB [H]

Identifier: 13474322

GI number: 13474322

Start: 4116931

End: 4117359

Strand: Direct

Name: pntAB [H]

Synonym: mlr5183

Alternate gene names: 13474322

Gene position: 4116931-4117359 (Clockwise)

Preceding gene: 13474321

Following gene: 13474323

Centisome position: 58.51

GC content: 64.8

Gene sequence:

>429_bases
GTGATGGATCAGTCCCTGCAGAAAGCCCTCGACCAGCTCGACCAGGCCTCCGCCGCCGTCAGGCTTGCGGTGCAGAACCT
GGCCAATGCTCCAGGTGGCGCCGAGGCGGCGGGTGATGCCGCCCACGCTCTGTCCGGCGGCGCCATCGATCCCTTCGTCT
TCCGCTTCGCCATCTTCGTGCTGGCGATCTTCGTCGGCTACTATGTCGTTTGGTCGGTGACCCCTGCGTTGCACACGCCG
CTGATGGCCGTCACCAACGCCATCTCGTCGGTCATCGTCGTCGGCGCGCTGCTCGCCGTCGGCATCGCCGCTTCCGGTGT
TGCCGCCGGCTTTGGCTTCGTCGCGCTGATGCTGGTCTCGGTCAACATCTTCGGCGGCTTCCTCGTCACCCAGCGCATGC
TGGCAATGTACAAGAAGAAGGACAAGTAG

Upstream 100 bases:

>100_bases
CCGATGCTTCGGCTGCGCCCAAAAAGCCCGCGCCAAAGAAGACAGCCGCGTCCAAATCGTCCTCGCCCAAGTCGTCCTCG
CCCAAGTCGAAAGGCACAGC

Downstream 100 bases:

>100_bases
AGCGCCATGAACGCCAACTTCGCGTCCTTCCTCTATCTCGTCTCCGGCGTCCTGTTCATCATGGCGCTGCGCGGCCTGTC
GCATCCGACCACCAGCCGCC

Product: nicotinamide nucleotide transhydrogenase, subunit alpha2

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha 2; Proton-translocating transhydrogenase component 2; Pyridine nucleotide transhydrogenase subunit alpha 2; dII [H]

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MMDQSLQKALDQLDQASAAVRLAVQNLANAPGGAEAAGDAAHALSGGAIDPFVFRFAIFVLAIFVGYYVVWSVTPALHTP
LMAVTNAISSVIVVGALLAVGIAASGVAAGFGFVALMLVSVNIFGGFLVTQRMLAMYKKKDK

Sequences:

>Translated_142_residues
MMDQSLQKALDQLDQASAAVRLAVQNLANAPGGAEAAGDAAHALSGGAIDPFVFRFAIFVLAIFVGYYVVWSVTPALHTP
LMAVTNAISSVIVVGALLAVGIAASGVAAGFGFVALMLVSVNIFGGFLVTQRMLAMYKKKDK
>Mature_142_residues
MMDQSLQKALDQLDQASAAVRLAVQNLANAPGGAEAAGDAAHALSGGAIDPFVFRFAIFVLAIFVGYYVVWSVTPALHTP
LMAVTNAISSVIVVGALLAVGIAASGVAAGFGFVALMLVSVNIFGGFLVTQRMLAMYKKKDK

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI122939155, Length=83, Percent_Identity=55.421686746988, Blast_Score=86, Evalue=7e-18,
Organism=Homo sapiens, GI122939153, Length=83, Percent_Identity=55.421686746988, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1787887, Length=89, Percent_Identity=58.4269662921348, Blast_Score=107, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17550456, Length=85, Percent_Identity=54.1176470588235, Blast_Score=89, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 14658; Mature: 14658

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDQSLQKALDQLDQASAAVRLAVQNLANAPGGAEAAGDAAHALSGGAIDPFVFRFAIFV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHH
LAIFVGYYVVWSVTPALHTPLMAVTNAISSVIVVGALLAVGIAASGVAAGFGFVALMLVS
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNIFGGFLVTQRMLAMYKKKDK
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMDQSLQKALDQLDQASAAVRLAVQNLANAPGGAEAAGDAAHALSGGAIDPFVFRFAIFV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHH
LAIFVGYYVVWSVTPALHTPLMAVTNAISSVIVVGALLAVGIAASGVAAGFGFVALMLVS
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNIFGGFLVTQRMLAMYKKKDK
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]