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The map label for this gene is aglR [H]

Identifier: 13474265

GI number: 13474265

Start: 4052888

End: 4053922

Strand: Direct

Name: aglR [H]

Synonym: mlr5115

Alternate gene names: 13474265

Gene position: 4052888-4053922 (Clockwise)

Preceding gene: 13474259

Following gene: 13474280

Centisome position: 57.6

GC content: 67.44

Gene sequence:

>1035_bases
ATGGAGACCATTGTGAACCTCAAGCAGCTCGCACAGATGCTGGCGCTTTCGCAGACCACGGTAAGCCGGGCATTGAACGG
CTATCCAGAGGTCAACGAGGAAACGCGCAGGCGCGTCGTGGACGCTGCCAAGCGCCATGGCTATCGCCCCAATCCGAGCG
CGCGGCGGCTGGCGACCGGCAAGTCCGGCATGATCGGCTATGTCCTGCCGACGGGCGCGGCCGTCGACATCGACCCGCAT
TTCGTCGAATTCCTCTCCGGCCTCGGCGATTATGCCCGCTCGCACGAGCTTGATCTCGTGCTGTCGCCGGCCGATGCCGA
CGACCAGGAGACGACCTATCGGCGCATCGTCGCCAACCGACAGGTCGATGCCGTCTATATCTCCTCGCCGCGGCCGCAGG
ACAGCCGGGTGGCGCAGGTCAGCACGCTCGGCATTCCCTTCCTCGTCCATGGCCGCAGCGAAGGCTTCGATTTCGACTAT
CCCTATCTCGACATCGACAATGAGGCAGCCTTCCACGAGGCGGCGCGGCTGCTGGTCCAGCTCGGCCACCGGCGGCTGGC
ACTGATCAATGGCGACGACCGCGAGACCTTCGCCATCCATCGCGAGCGCGGCGTGCGCCGGGCGCTCGCGGCAAGCGGAC
TGAGCCTGCGCGAACGCCATGTCTGCTCCGTGGTCATGACCGAAGAGAACGGCTATCGCGCCACCAGGCGCCTGCTCGAG
GAGGGCGATGCGCCGACGGCGATCGCCTGCTCCAGCCTGATCATGGCGCTGGGCGTCGTGCGCGCGGTGCGCGACCTCGG
CCTCACCATTCCCGGCGATGTCTCGCTGATCGCCCATGACGACGTCTTCCCCTGGTTGAAGCCGGAGAATTTTTCCGTGC
CGCTGTCGACGACGCGATCATCCATCCGCCTTGCCGGCGCCCGCGTCGCCGAGCGGCTCGCGGCGCGGATTTCAGGGCTG
GAAGAAGGCGCCCGCGGCGAAGTCTGGCCGGTCGATCTGGTGGTCCGGGGCTCGGTCGCCGGGGCGCCGGCCTAG

Upstream 100 bases:

>100_bases
AATTTTTGTTTCAAACTGGTCTCAACCCCGACTATGATCGTCTCGATACTGTCGCGCCCTTATGCGTTGGGTCGATTCAA
TTTAAAAGCGCTTTGAGGGA

Downstream 100 bases:

>100_bases
GATCTGACCTCGATCAAGGGTCCGGTGCGCCCTGTTTGCGCCCTGCGTATCCCTTAGTCCGGACCGGGATCACCTCACAT
GGACCCTGTTAACGCCGCAT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
METIVNLKQLAQMLALSQTTVSRALNGYPEVNEETRRRVVDAAKRHGYRPNPSARRLATGKSGMIGYVLPTGAAVDIDPH
FVEFLSGLGDYARSHELDLVLSPADADDQETTYRRIVANRQVDAVYISSPRPQDSRVAQVSTLGIPFLVHGRSEGFDFDY
PYLDIDNEAAFHEAARLLVQLGHRRLALINGDDRETFAIHRERGVRRALAASGLSLRERHVCSVVMTEENGYRATRRLLE
EGDAPTAIACSSLIMALGVVRAVRDLGLTIPGDVSLIAHDDVFPWLKPENFSVPLSTTRSSIRLAGARVAERLAARISGL
EEGARGEVWPVDLVVRGSVAGAPA

Sequences:

>Translated_344_residues
METIVNLKQLAQMLALSQTTVSRALNGYPEVNEETRRRVVDAAKRHGYRPNPSARRLATGKSGMIGYVLPTGAAVDIDPH
FVEFLSGLGDYARSHELDLVLSPADADDQETTYRRIVANRQVDAVYISSPRPQDSRVAQVSTLGIPFLVHGRSEGFDFDY
PYLDIDNEAAFHEAARLLVQLGHRRLALINGDDRETFAIHRERGVRRALAASGLSLRERHVCSVVMTEENGYRATRRLLE
EGDAPTAIACSSLIMALGVVRAVRDLGLTIPGDVSLIAHDDVFPWLKPENFSVPLSTTRSSIRLAGARVAERLAARISGL
EEGARGEVWPVDLVVRGSVAGAPA
>Mature_344_residues
METIVNLKQLAQMLALSQTTVSRALNGYPEVNEETRRRVVDAAKRHGYRPNPSARRLATGKSGMIGYVLPTGAAVDIDPH
FVEFLSGLGDYARSHELDLVLSPADADDQETTYRRIVANRQVDAVYISSPRPQDSRVAQVSTLGIPFLVHGRSEGFDFDY
PYLDIDNEAAFHEAARLLVQLGHRRLALINGDDRETFAIHRERGVRRALAASGLSLRERHVCSVVMTEENGYRATRRLLE
EGDAPTAIACSSLIMALGVVRAVRDLGLTIPGDVSLIAHDDVFPWLKPENFSVPLSTTRSSIRLAGARVAERLAARISGL
EEGARGEVWPVDLVVRGSVAGAPA

Specific function: Probable regulatory protein for the binding-protein- dependent transport system for alpha-glucosides such as sucrose, maltose and trehalose [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=347, Percent_Identity=29.3948126801153, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1787948, Length=344, Percent_Identity=28.1976744186047, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1789068, Length=302, Percent_Identity=26.4900662251656, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787580, Length=276, Percent_Identity=24.2753623188406, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789202, Length=282, Percent_Identity=27.6595744680851, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786540, Length=348, Percent_Identity=26.4367816091954, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789456, Length=320, Percent_Identity=26.875, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790194, Length=340, Percent_Identity=24.7058823529412, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788474, Length=331, Percent_Identity=25.0755287009063, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787906, Length=341, Percent_Identity=23.4604105571848, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI48994940, Length=327, Percent_Identity=24.4648318042813, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37625; Mature: 37625

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METIVNLKQLAQMLALSQTTVSRALNGYPEVNEETRRRVVDAAKRHGYRPNPSARRLATG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCC
KSGMIGYVLPTGAAVDIDPHFVEFLSGLGDYARSHELDLVLSPADADDQETTYRRIVANR
CCCCEEEEECCCCEEECCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCC
QVDAVYISSPRPQDSRVAQVSTLGIPFLVHGRSEGFDFDYPYLDIDNEAAFHEAARLLVQ
CCCEEEECCCCCCCCHHEEHHCCCCEEEEECCCCCCCCCCCEEECCCCHHHHHHHHHHHH
LGHRRLALINGDDRETFAIHRERGVRRALAASGLSLRERHVCSVVMTEENGYRATRRLLE
HCCCEEEEEECCCCCEEEEHHHHHHHHHHHHCCCCHHHHCEEEEEEECCCCHHHHHHHHH
EGDAPTAIACSSLIMALGVVRAVRDLGLTIPGDVSLIAHDDVFPWLKPENFSVPLSTTRS
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHCHH
SIRLAGARVAERLAARISGLEEGARGEVWPVDLVVRGSVAGAPA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCC
>Mature Secondary Structure
METIVNLKQLAQMLALSQTTVSRALNGYPEVNEETRRRVVDAAKRHGYRPNPSARRLATG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCC
KSGMIGYVLPTGAAVDIDPHFVEFLSGLGDYARSHELDLVLSPADADDQETTYRRIVANR
CCCCEEEEECCCCEEECCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCC
QVDAVYISSPRPQDSRVAQVSTLGIPFLVHGRSEGFDFDYPYLDIDNEAAFHEAARLLVQ
CCCEEEECCCCCCCCHHEEHHCCCCEEEEECCCCCCCCCCCEEECCCCHHHHHHHHHHHH
LGHRRLALINGDDRETFAIHRERGVRRALAASGLSLRERHVCSVVMTEENGYRATRRLLE
HCCCEEEEEECCCCCEEEEHHHHHHHHHHHHCCCCHHHHCEEEEEEECCCCHHHHHHHHH
EGDAPTAIACSSLIMALGVVRAVRDLGLTIPGDVSLIAHDDVFPWLKPENFSVPLSTTRS
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHCHH
SIRLAGARVAERLAARISGLEEGARGEVWPVDLVVRGSVAGAPA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]