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The map label for this gene is czcN [H]

Identifier: 13474221

GI number: 13474221

Start: 4008599

End: 4009225

Strand: Reverse

Name: czcN [H]

Synonym: mll5060

Alternate gene names: 13474221

Gene position: 4009225-4008599 (Counterclockwise)

Preceding gene: 13474222

Following gene: 13474220

Centisome position: 56.98

GC content: 63.16

Gene sequence:

>627_bases
TTGGACAACGAACTCAAATACGGGCTGGGCAATTACCAGCAGATGCGTCGGCTGGTGCTTGCCGTGCTCGTGGTGGTGCT
GTTTCTGGCGCTGCTGTTTGGCCAGTCGACCTTCCCACCCGACACGCCGGTGCATGAAACAATCGAGATGTTCGGCGTGC
TGCTGATCTTCCTCGGCATCGTCGGCCGCCTCTGGGCGACGCTCTATATAGGCGGGCGCAAATCCTCCGAGGTGGTCACC
GGCGGGCCCTATTCGATCACTCGCAACCCGCTCTATGTGTTCTCGACGGTGGCCGCGGCCGGCGTCGGCGCGCAGATCGG
CTCGTTCTCGGGCATCATCCTGTTCGCACTGCTGTGCGCGGGCGCCTTCCATATCGTCATCCTGCGCGAGGAGAAATTCC
TCAAGGAAGCGCTCGGCGCGCCCTATCAGGCCTATCTGGACAAGGTGCCGCGCTTCTTCCCGAAGCTTTCCCTCTACCAG
GAGGGCGACACCGGCAGCTTCAAGCCGCGCCTGCTGTTGACCACGCTGCTCGACGGCCTGGTGTTCCTGATCGCGCTGCC
GGCCTTCGAACTGATCGACGGCGCGCAGCAGTCGGGCATGCTTCCGGTGTGGTTCAAGCTGCCCTGA

Upstream 100 bases:

>100_bases
GCTGCGATCGCCGGCTTTGTTTTTTATGCATGTCGTCCTCCCAAAACCGGACCCACTTTTGGGCGACATGCAATAGGCTC
CTCGACGATCGGATATCCCC

Downstream 100 bases:

>100_bases
GCGGGGACAGAGCGTCGCACGGCTTCAGGTGTTGCGCACCGGCCGTGTTTGACGTATAGGACCGCCGTTCAAGAAAACCG
CCCGGCAGGGCATGCCGTGG

Product: nickel-cobalt-cadmium resistance protein NCCN

Products: NA

Alternate protein names: Cation efflux system protein CzcN [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MDNELKYGLGNYQQMRRLVLAVLVVVLFLALLFGQSTFPPDTPVHETIEMFGVLLIFLGIVGRLWATLYIGGRKSSEVVT
GGPYSITRNPLYVFSTVAAAGVGAQIGSFSGIILFALLCAGAFHIVILREEKFLKEALGAPYQAYLDKVPRFFPKLSLYQ
EGDTGSFKPRLLLTTLLDGLVFLIALPAFELIDGAQQSGMLPVWFKLP

Sequences:

>Translated_208_residues
MDNELKYGLGNYQQMRRLVLAVLVVVLFLALLFGQSTFPPDTPVHETIEMFGVLLIFLGIVGRLWATLYIGGRKSSEVVT
GGPYSITRNPLYVFSTVAAAGVGAQIGSFSGIILFALLCAGAFHIVILREEKFLKEALGAPYQAYLDKVPRFFPKLSLYQ
EGDTGSFKPRLLLTTLLDGLVFLIALPAFELIDGAQQSGMLPVWFKLP
>Mature_208_residues
MDNELKYGLGNYQQMRRLVLAVLVVVLFLALLFGQSTFPPDTPVHETIEMFGVLLIFLGIVGRLWATLYIGGRKSSEVVT
GGPYSITRNPLYVFSTVAAAGVGAQIGSFSGIILFALLCAGAFHIVILREEKFLKEALGAPYQAYLDKVPRFFPKLSLYQ
EGDTGSFKPRLLLTTLLDGLVFLIALPAFELIDGAQQSGMLPVWFKLP

Specific function: Component of the CZC cation-efflux system that confers resistance to cobalt, zinc and cadmium [H]

COG id: COG2020

COG function: function code O; Putative protein-S-isoprenylcysteine methyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To A.xylosoxydans nccN [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007269 [H]

Pfam domain/function: PF04140 ICMT [H]

EC number: NA

Molecular weight: Translated: 22834; Mature: 22834

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNELKYGLGNYQQMRRLVLAVLVVVLFLALLFGQSTFPPDTPVHETIEMFGVLLIFLGI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
VGRLWATLYIGGRKSSEVVTGGPYSITRNPLYVFSTVAAAGVGAQIGSFSGIILFALLCA
HHHHHHHHHCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCHHHHCHHHHHHHHHHHH
GAFHIVILREEKFLKEALGAPYQAYLDKVPRFFPKLSLYQEGDTGSFKPRLLLTTLLDGL
HHHEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHCCHHEECCCCCCCCHHHHHHHHHHHH
VFLIALPAFELIDGAQQSGMLPVWFKLP
HHHHHHHHHHHHHCHHHCCCCEEEEECC
>Mature Secondary Structure
MDNELKYGLGNYQQMRRLVLAVLVVVLFLALLFGQSTFPPDTPVHETIEMFGVLLIFLGI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
VGRLWATLYIGGRKSSEVVTGGPYSITRNPLYVFSTVAAAGVGAQIGSFSGIILFALLCA
HHHHHHHHHCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCHHHHCHHHHHHHHHHHH
GAFHIVILREEKFLKEALGAPYQAYLDKVPRFFPKLSLYQEGDTGSFKPRLLLTTLLDGL
HHHEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHCCHHEECCCCCCCCHHHHHHHHHHHH
VFLIALPAFELIDGAQQSGMLPVWFKLP
HHHHHHHHHHHHHCHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9044283; 7766206 [H]