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The map label for this gene is rhtB [H]

Identifier: 13474194

GI number: 13474194

Start: 3981356

End: 3981979

Strand: Direct

Name: rhtB [H]

Synonym: mlr5029

Alternate gene names: 13474194

Gene position: 3981356-3981979 (Clockwise)

Preceding gene: 13474193

Following gene: 13474196

Centisome position: 56.58

GC content: 64.42

Gene sequence:

>624_bases
ATGTCCTTCGAGAACTGGGCCGCTTTCGCCGCCGCGTCGACCATCCTGCTCGTCATTCCGGATCCAACCATCCTGCTGGT
CGTGTCCTATGCGCTGGGCCAGGGCTGGCGCACAGCTTTGCCGATGGCGGTTGGCGTGGCGCTCGGCGACTTCACCGCCA
TGACCTTGTCGATGCTCGGCATCGGCGCGCTGCTTGCCGCTTCGGCGACCGTCTTCACCGTCCTGAAGCTGATCGGCGCC
GGCTATCTGATCTATCTCGGCGTAAAACTGTTCCGCGCCGGCGGCGCGCTGAAGGCCGAGCCGCGAACCGATGTGGTCTC
TTCGGCCAAGATGATGGCGCACGCCTGGCTGGTCACCGCGCTCAACCCGAAAAGCATCACTTTCTTTGTCGCCTTCCTGC
CGCAGTTCCTCGACCGGCATGCCGATTTCTGGACGCAGATGCTGATCTTCGAGACGACGTTCCTGGCGCTCGCCTTTGCC
AATGCCTTCGGCTACGCGCTGATCGCGGCACGCGCCCGCAATGTCGTGCGCAATCCCAAGGCGATCCGCATCTTCAACCG
CACCGGCGGCACGCTGCTGGTCGGCGCCGGCATCGCCACCGTGGCGATGCGTTCGGGGAATTAG

Upstream 100 bases:

>100_bases
GCGGTTGCTGTTCGTAACCGCGCAAAAACAGAGATCAGACCTCTTTACATTCCCCCTGGGCTGAGGATTTATCCTTTTCC
TTAACCCAAGGGAGACAGAC

Downstream 100 bases:

>100_bases
GCCTTTTATTCGACCATTCGAAACCGGTTCCGGTTTCGAATGGTCTGGTTCACCACTTCATGCTGATACCGACATTGCCC
TCGAGGATGCGGCGCTTGTC

Product: hypothetical protein

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSFENWAAFAAASTILLVIPDPTILLVVSYALGQGWRTALPMAVGVALGDFTAMTLSMLGIGALLAASATVFTVLKLIGA
GYLIYLGVKLFRAGGALKAEPRTDVVSSAKMMAHAWLVTALNPKSITFFVAFLPQFLDRHADFWTQMLIFETTFLALAFA
NAFGYALIAARARNVVRNPKAIRIFNRTGGTLLVGAGIATVAMRSGN

Sequences:

>Translated_207_residues
MSFENWAAFAAASTILLVIPDPTILLVVSYALGQGWRTALPMAVGVALGDFTAMTLSMLGIGALLAASATVFTVLKLIGA
GYLIYLGVKLFRAGGALKAEPRTDVVSSAKMMAHAWLVTALNPKSITFFVAFLPQFLDRHADFWTQMLIFETTFLALAFA
NAFGYALIAARARNVVRNPKAIRIFNRTGGTLLVGAGIATVAMRSGN
>Mature_206_residues
SFENWAAFAAASTILLVIPDPTILLVVSYALGQGWRTALPMAVGVALGDFTAMTLSMLGIGALLAASATVFTVLKLIGAG
YLIYLGVKLFRAGGALKAEPRTDVVSSAKMMAHAWLVTALNPKSITFFVAFLPQFLDRHADFWTQMLIFETTFLALAFAN
AFGYALIAARARNVVRNPKAIRIFNRTGGTLLVGAGIATVAMRSGN

Specific function: Conducts the efflux of homoserine and homoserine lactone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=202, Percent_Identity=31.6831683168317, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1788099, Length=138, Percent_Identity=28.9855072463768, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22033; Mature: 21902

Theoretical pI: Translated: 10.89; Mature: 10.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFENWAAFAAASTILLVIPDPTILLVVSYALGQGWRTALPMAVGVALGDFTAMTLSMLG
CCCCHHHHHHHHCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGALLAASATVFTVLKLIGAGYLIYLGVKLFRAGGALKAEPRTDVVSSAKMMAHAWLVTA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHEE
LNPKSITFFVAFLPQFLDRHADFWTQMLIFETTFLALAFANAFGYALIAARARNVVRNPK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AIRIFNRTGGTLLVGAGIATVAMRSGN
EEEEEECCCCEEEEECCCEEEEEECCC
>Mature Secondary Structure 
SFENWAAFAAASTILLVIPDPTILLVVSYALGQGWRTALPMAVGVALGDFTAMTLSMLG
CCCHHHHHHHHCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGALLAASATVFTVLKLIGAGYLIYLGVKLFRAGGALKAEPRTDVVSSAKMMAHAWLVTA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHEE
LNPKSITFFVAFLPQFLDRHADFWTQMLIFETTFLALAFANAFGYALIAARARNVVRNPK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AIRIFNRTGGTLLVGAGIATVAMRSGN
EEEEEECCCCEEEEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]