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The map label for this gene is coaA

Identifier: 13474188

GI number: 13474188

Start: 3975335

End: 3976294

Strand: Direct

Name: coaA

Synonym: mlr5019

Alternate gene names: 13474188

Gene position: 3975335-3976294 (Clockwise)

Preceding gene: 13474187

Following gene: 13474193

Centisome position: 56.5

GC content: 61.56

Gene sequence:

>960_bases
ATGGATCAGCTCGCGCAAACCGAGAAATATTCCCCCTTTCGTTTCTTTTCGGCCGAGCAATGGTCGCGATTCCGCGCCGA
CACGCCACTGACGCTGAGCGAGGACGAGTTCCGCCGCTTGCGTTCGCTTAACGACCCGGTCGACCTCGAGGAGGTCAAGC
GCATCTATTTGTCGCTGTCGCGGCTTCTGTCCGCCCATGTCGAGGCGAGCCAGCTCTTGTTCCGGCAGCGCCAGGCCTTC
TTCAACGCCGTCGATATCGTCAAGACGCCGTTCATCATCGGCATCGCCGGCTCCGTCGCCGTCGGCAAATCGACCACCGC
GCGCGTGCTGAAGGAGCTTCTGGCGCGCTGGCCGTCGAGCCCCAAGGTCGATCTCATCACCACCGACGGCTTCCTGCTGC
CCAACGAGGTGCTGCGCCGTGAGAACCTGATGGAACGCAAGGGTTTTCCCGACAGTTACGATGTCGGCGCGCTGCTGCGC
TTCCTCTCGGGCATCAAGTCGGCGCTGCCCGATGTCCGCGCGCCGGTCTATTCGCACCTCACCTATGACGTCATTCCGGG
CGAGTTCGTCACCATCGACCGGCCCGACATATTGATCTTCGAAGGCATCAATGTCCTGCAGCCGGGCAAGCTGCCGCAGG
ACGGCAAGATCGTGCCCTTCCTGTCCGACTTTTTCGACTTTGCCATCTATATCGATGCCGACGAGAAGCTGATCCATGAG
TGGTATATCTCGCGCTTCATGCGGCTGCGCGAGACCGCCTTCCGCAATCCGGACTCCTTCTTCCACCGCTACTCGCAGCT
TTCGGAGGAAGCGGCGCGCGCCATCGCCGAAGGCCTGTGGTCCAACATCAATCTGAAGAATTTGCGCGAGAACATCTTGC
CGACGCGCGCCCGCGCCGACCTCATCCTGCGCAAGGGCGCCGACCATCTGGTCGAGGAAGTGGCGCTGCGCAAACTTTAG

Upstream 100 bases:

>100_bases
CGACGTGCTCAAGGAGCTCGAAAGCCGCACCGGGCGTTCGGGCATCGCCGAAAAGGCGTCACGGCCCAAGGGCTGACCGC
GAGGGAGGGCAGGTATCTCG

Downstream 100 bases:

>100_bases
GGCAATTCCAGGAAATGTGGCGGCCCTGCCACCGGCAGGCCCGCCACCTCGACGTTCATGTCATCGGCGTCGCGGCTCAG
CCATTGGCGAACGGCACGGC

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MDQLAQTEKYSPFRFFSAEQWSRFRADTPLTLSEDEFRRLRSLNDPVDLEEVKRIYLSLSRLLSAHVEASQLLFRQRQAF
FNAVDIVKTPFIIGIAGSVAVGKSTTARVLKELLARWPSSPKVDLITTDGFLLPNEVLRRENLMERKGFPDSYDVGALLR
FLSGIKSALPDVRAPVYSHLTYDVIPGEFVTIDRPDILIFEGINVLQPGKLPQDGKIVPFLSDFFDFAIYIDADEKLIHE
WYISRFMRLRETAFRNPDSFFHRYSQLSEEAARAIAEGLWSNINLKNLRENILPTRARADLILRKGADHLVEEVALRKL

Sequences:

>Translated_319_residues
MDQLAQTEKYSPFRFFSAEQWSRFRADTPLTLSEDEFRRLRSLNDPVDLEEVKRIYLSLSRLLSAHVEASQLLFRQRQAF
FNAVDIVKTPFIIGIAGSVAVGKSTTARVLKELLARWPSSPKVDLITTDGFLLPNEVLRRENLMERKGFPDSYDVGALLR
FLSGIKSALPDVRAPVYSHLTYDVIPGEFVTIDRPDILIFEGINVLQPGKLPQDGKIVPFLSDFFDFAIYIDADEKLIHE
WYISRFMRLRETAFRNPDSFFHRYSQLSEEAARAIAEGLWSNINLKNLRENILPTRARADLILRKGADHLVEEVALRKL
>Mature_319_residues
MDQLAQTEKYSPFRFFSAEQWSRFRADTPLTLSEDEFRRLRSLNDPVDLEEVKRIYLSLSRLLSAHVEASQLLFRQRQAF
FNAVDIVKTPFIIGIAGSVAVGKSTTARVLKELLARWPSSPKVDLITTDGFLLPNEVLRRENLMERKGFPDSYDVGALLR
FLSGIKSALPDVRAPVYSHLTYDVIPGEFVTIDRPDILIFEGINVLQPGKLPQDGKIVPFLSDFFDFAIYIDADEKLIHE
WYISRFMRLRETAFRNPDSFFHRYSQLSEEAARAIAEGLWSNINLKNLRENILPTRARADLILRKGADHLVEEVALRKL

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family

Homologues:

Organism=Escherichia coli, GI1790409, Length=312, Percent_Identity=54.4871794871795, Blast_Score=332, Evalue=2e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAA_RHILO (Q98CS9)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_105756.1
- ProteinModelPortal:   Q98CS9
- SMR:   Q98CS9
- GeneID:   1228417
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr5019
- NMPDR:   fig|266835.1.peg.3860
- HOGENOM:   HBG732538
- OMA:   GLNVLQP
- ProtClustDB:   PRK05439
- BRENDA:   2.7.1.33
- GO:   GO:0005737
- HAMAP:   MF_00215
- InterPro:   IPR004566
- InterPro:   IPR006083
- PANTHER:   PTHR10285:SF7
- PIRSF:   PIRSF000545
- TIGRFAMs:   TIGR00554

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.33

Molecular weight: Translated: 36662; Mature: 36662

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQLAQTEKYSPFRFFSAEQWSRFRADTPLTLSEDEFRRLRSLNDPVDLEEVKRIYLSLS
CCCCCCCCCCCCEEECCHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
RLLSAHVEASQLLFRQRQAFFNAVDIVKTPFIIGIAGSVAVGKSTTARVLKELLARWPSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHCCCCHHHHHHHHHHHHCCCC
PKVDLITTDGFLLPNEVLRRENLMERKGFPDSYDVGALLRFLSGIKSALPDVRAPVYSHL
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHC
TYDVIPGEFVTIDRPDILIFEGINVLQPGKLPQDGKIVPFLSDFFDFAIYIDADEKLIHE
CCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHEEEEECCHHHHHHH
WYISRFMRLRETAFRNPDSFFHRYSQLSEEAARAIAEGLWSNINLKNLRENILPTRARAD
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHH
LILRKGADHLVEEVALRKL
HHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MDQLAQTEKYSPFRFFSAEQWSRFRADTPLTLSEDEFRRLRSLNDPVDLEEVKRIYLSLS
CCCCCCCCCCCCEEECCHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
RLLSAHVEASQLLFRQRQAFFNAVDIVKTPFIIGIAGSVAVGKSTTARVLKELLARWPSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHCCCCHHHHHHHHHHHHCCCC
PKVDLITTDGFLLPNEVLRRENLMERKGFPDSYDVGALLRFLSGIKSALPDVRAPVYSHL
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHC
TYDVIPGEFVTIDRPDILIFEGINVLQPGKLPQDGKIVPFLSDFFDFAIYIDADEKLIHE
CCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHEEEEECCHHHHHHH
WYISRFMRLRETAFRNPDSFFHRYSQLSEEAARAIAEGLWSNINLKNLRENILPTRARAD
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHH
LILRKGADHLVEEVALRKL
HHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968