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The map label for this gene is hslV

Identifier: 13474179

GI number: 13474179

Start: 3969771

End: 3970304

Strand: Reverse

Name: hslV

Synonym: mll5007

Alternate gene names: 13474179

Gene position: 3970304-3969771 (Counterclockwise)

Preceding gene: 13474189

Following gene: 13474178

Centisome position: 56.43

GC content: 64.98

Gene sequence:

>534_bases
ATGCACGCCACGACCATCGTGACGGTGCGCAAGGGCAACAAGGTGGTGATCGCCGGCGACGGCCAGGTCAGCCTTGGCCA
GACCATCATGAAGGGCAATGCCCGCAAGGTGCGCCGCATCGGCAAGGGCGGCAATGTGATCGCCGGTTTCGCCGGCGCTA
CGGCGGACGCCTTCACGCTGCTGGAGCGGCTGGAAGCCAAGCTCGAACAATATCCCGACCAGCTGACGCGCGCCTGCGTC
GAGCTTGCCAAGGACTGGCGCACCGACCGCTATCTGCGCCGGCTGGAGGCGATGATGCTGGTGGCCGACAAGTCGGTTTC
GCTGGCGCTGACCGGCACCGGCGACGTGCTCGAACCCGAACACGGGGTCATGGCCATCGGTTCAGGCGGCAATTACGCGC
TGGCTGCTGCCCGCGCGCTGATGGACACCGACAAGGATGCCGAGGAGATCGCCCGCAAGGCGATGCAGATCGCCTCCGAC
ATCTGTGTCTACACCAACAACAATTTCGTCGTCGAAACGCTCGATGCCGCCTGA

Upstream 100 bases:

>100_bases
GGTCCCATGCATACATATGGCCGATAAAATCACTCGTACCGCGCCAATCGCCTTTTGGGATCGCGCGAATCGGAGCCAAT
AAATGTCTGATAATCTGACC

Downstream 100 bases:

>100_bases
GAAGGTGGTGCTCTACGATTTTCGGCCGGTTACCGAAAAGGACCTGCCGATGATCGCCGGCTGGCTGGCCGAGCCTGAAG
TGGCCGAGTGGTGGAACGAT

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MHATTIVTVRKGNKVVIAGDGQVSLGQTIMKGNARKVRRIGKGGNVIAGFAGATADAFTLLERLEAKLEQYPDQLTRACV
ELAKDWRTDRYLRRLEAMMLVADKSVSLALTGTGDVLEPEHGVMAIGSGGNYALAAARALMDTDKDAEEIARKAMQIASD
ICVYTNNNFVVETLDAA

Sequences:

>Translated_177_residues
MHATTIVTVRKGNKVVIAGDGQVSLGQTIMKGNARKVRRIGKGGNVIAGFAGATADAFTLLERLEAKLEQYPDQLTRACV
ELAKDWRTDRYLRRLEAMMLVADKSVSLALTGTGDVLEPEHGVMAIGSGGNYALAAARALMDTDKDAEEIARKAMQIASD
ICVYTNNNFVVETLDAA
>Mature_177_residues
MHATTIVTVRKGNKVVIAGDGQVSLGQTIMKGNARKVRRIGKGGNVIAGFAGATADAFTLLERLEAKLEQYPDQLTRACV
ELAKDWRTDRYLRRLEAMMLVADKSVSLALTGTGDVLEPEHGVMAIGSGGNYALAAARALMDTDKDAEEIARKAMQIASD
ICVYTNNNFVVETLDAA

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=172, Percent_Identity=61.046511627907, Blast_Score=207, Evalue=5e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_RHILO (Q98CT8)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_105747.1
- ProteinModelPortal:   Q98CT8
- SMR:   Q98CT8
- MEROPS:   T01.006
- GeneID:   1228408
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll5007
- NMPDR:   fig|266835.1.peg.3851
- HOGENOM:   HBG288822
- OMA:   AADICVY
- ProtClustDB:   PRK05456
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.-

Molecular weight: Translated: 18986; Mature: 18986

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: ACT_SITE 4-4

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHATTIVTVRKGNKVVIAGDGQVSLGQTIMKGNARKVRRIGKGGNVIAGFAGATADAFTL
CCCEEEEEEECCCEEEEEECCCCCHHHHHHHCCHHHHHHHCCCCCEEEECCCCHHHHHHH
LERLEAKLEQYPDQLTRACVELAKDWRTDRYLRRLEAMMLVADKSVSLALTGTGDVLEPE
HHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEECCCEEEEEECCCCCCCCC
HGVMAIGSGGNYALAAARALMDTDKDAEEIARKAMQIASDICVYTNNNFVVETLDAA
CCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEECCCEEEEEECCC
>Mature Secondary Structure
MHATTIVTVRKGNKVVIAGDGQVSLGQTIMKGNARKVRRIGKGGNVIAGFAGATADAFTL
CCCEEEEEEECCCEEEEEECCCCCHHHHHHHCCHHHHHHHCCCCCEEEECCCCHHHHHHH
LERLEAKLEQYPDQLTRACVELAKDWRTDRYLRRLEAMMLVADKSVSLALTGTGDVLEPE
HHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEECCCEEEEEECCCCCCCCC
HGVMAIGSGGNYALAAARALMDTDKDAEEIARKAMQIASDICVYTNNNFVVETLDAA
CCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968