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The map label for this gene is lsrR [H]

Identifier: 13474119

GI number: 13474119

Start: 3913518

End: 3914477

Strand: Reverse

Name: lsrR [H]

Synonym: mll4931

Alternate gene names: 13474119

Gene position: 3914477-3913518 (Counterclockwise)

Preceding gene: 13474121

Following gene: 13474117

Centisome position: 55.63

GC content: 65.52

Gene sequence:

>960_bases
GTGAATACCCGACAAGATGGCGGCAGCAACAGGCTGGACGACGCGGCGCGCGCCGGCTGGCTTTATTATGTCGCCGGCAA
CACACAGGACCAGATCGCCGCCACGCTCGGCATCTCGCGGCAGACGGCGCAGCGACTGGTGTCGCTGGCGGTGTCGGAAG
GCTTGATCAAGGTCCGTGTCGACCATCCGATCGCCAACTGCCTGGACCTTGCCGCCCGGCTGAAATCGCGTTTCGCGCTC
GACCTGGTCGAGGTGGTGCCGAGTGACCCGAATTCATCCTCCACCACCATCGGCATTGCCGAGGCGGCGGCGGCCGAGAT
CGAGCGGAGGCTGCGCTCGCCGACGCCGATCGTCATGGGCATCGGCACAGGGCGCACGCTGAAGGCGGCGATCGAGCAAT
TGCCGCCGATGGAATGCCCGCAGCACAAGGTGGTGTCCTTGACCGGCAACATTTCGCCGGACGGCTCGGCCGCCTTCTAC
AACGTCATCTTCACCATGGCCGACCGGGTCAAGGCGCGCTCCTTCCCGATGCCGCTTCCGGTCATCGCCTCCTCGCCGCA
GGAGCGCGAGATGCTGCTCAACCAGCCGATGATCCAGCCGACGCTGGCGCTTGCGGCGGAAGCCGATGTCACCTTCATCG
GCATCGGCGACCTCGGCCCGAAGGCCCCGCTCTACGAGGACGGCTTCATTTCCGAAAGCGAGTTGAAGGCCCTGCAAAAA
GCTGGCGGCATCGCCGAGATCGTCGGCTGGGTTTTCGACCGGGAAGGCCGCATGATCGAGGGCATCACCAACGACCGGGT
GTCGTCGGCATCGCTGCCGTCGCGCGAGAAATCGCTTGTCATTGCGCTCGCCATGGGCGAGCGCAAGCTGCCGGGCATCC
TGGCGGCCGTGAATCGCCGGCTGGTCAATGGTCTCATCACCGACGAACGGACGGCTACCGCTTTGCTGGCCAGCATCTGA

Upstream 100 bases:

>100_bases
CGCAAACAATTGCCCTTGAGATTGACAATTGCGCAGGAAGCCGTTCCCTGCGAGACTGAGGGCGGACCGCTCCTGTGAGC
AGCGGTTTCGGAGGCAGGAC

Downstream 100 bases:

>100_bases
CCGGGAACGCGGCGGCGCCTGCCGGCTACGGCCGCGGCGCCTGGCGATAAAGCCAACAAGTCTATTTATGCCGCCCGAAA
GGATCGTTGCCATCGAGGAG

Product: transcriptional regulator, operon regulator; SmoC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MNTRQDGGSNRLDDAARAGWLYYVAGNTQDQIAATLGISRQTAQRLVSLAVSEGLIKVRVDHPIANCLDLAARLKSRFAL
DLVEVVPSDPNSSSTTIGIAEAAAAEIERRLRSPTPIVMGIGTGRTLKAAIEQLPPMECPQHKVVSLTGNISPDGSAAFY
NVIFTMADRVKARSFPMPLPVIASSPQEREMLLNQPMIQPTLALAAEADVTFIGIGDLGPKAPLYEDGFISESELKALQK
AGGIAEIVGWVFDREGRMIEGITNDRVSSASLPSREKSLVIALAMGERKLPGILAAVNRRLVNGLITDERTATALLASI

Sequences:

>Translated_319_residues
MNTRQDGGSNRLDDAARAGWLYYVAGNTQDQIAATLGISRQTAQRLVSLAVSEGLIKVRVDHPIANCLDLAARLKSRFAL
DLVEVVPSDPNSSSTTIGIAEAAAAEIERRLRSPTPIVMGIGTGRTLKAAIEQLPPMECPQHKVVSLTGNISPDGSAAFY
NVIFTMADRVKARSFPMPLPVIASSPQEREMLLNQPMIQPTLALAAEADVTFIGIGDLGPKAPLYEDGFISESELKALQK
AGGIAEIVGWVFDREGRMIEGITNDRVSSASLPSREKSLVIALAMGERKLPGILAAVNRRLVNGLITDERTATALLASI
>Mature_319_residues
MNTRQDGGSNRLDDAARAGWLYYVAGNTQDQIAATLGISRQTAQRLVSLAVSEGLIKVRVDHPIANCLDLAARLKSRFAL
DLVEVVPSDPNSSSTTIGIAEAAAAEIERRLRSPTPIVMGIGTGRTLKAAIEQLPPMECPQHKVVSLTGNISPDGSAAFY
NVIFTMADRVKARSFPMPLPVIASSPQEREMLLNQPMIQPTLALAAEADVTFIGIGDLGPKAPLYEDGFISESELKALQK
AGGIAEIVGWVFDREGRMIEGITNDRVSSASLPSREKSLVIALAMGERKLPGILAAVNRRLVNGLITDERTATALLASI

Specific function: In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFGE operon and its own transcription. In the presence of AI-2, lsrR is inactivated by binding phospho- AI-2, leading to the transcription of the lsr genes [H]

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=317, Percent_Identity=27.7602523659306, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI87082414, Length=313, Percent_Identity=24.6006389776358, Blast_Score=107, Evalue=9e-25,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 34080; Mature: 34080

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTRQDGGSNRLDDAARAGWLYYVAGNTQDQIAATLGISRQTAQRLVSLAVSEGLIKVRV
CCCCCCCCCCCCCHHHHCCEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEE
DHPIANCLDLAARLKSRFALDLVEVVPSDPNSSSTTIGIAEAAAAEIERRLRSPTPIVMG
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCEEEE
IGTGRTLKAAIEQLPPMECPQHKVVSLTGNISPDGSAAFYNVIFTMADRVKARSFPMPLP
CCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
VIASSPQEREMLLNQPMIQPTLALAAEADVTFIGIGDLGPKAPLYEDGFISESELKALQK
HHCCCCHHHHHHHCCCCCCHHHHHEECCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHH
AGGIAEIVGWVFDREGRMIEGITNDRVSSASLPSREKSLVIALAMGERKLPGILAAVNRR
CCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHH
LVNGLITDERTATALLASI
HHHHHHCCCHHHHHHHHCC
>Mature Secondary Structure
MNTRQDGGSNRLDDAARAGWLYYVAGNTQDQIAATLGISRQTAQRLVSLAVSEGLIKVRV
CCCCCCCCCCCCCHHHHCCEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEE
DHPIANCLDLAARLKSRFALDLVEVVPSDPNSSSTTIGIAEAAAAEIERRLRSPTPIVMG
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCEEEE
IGTGRTLKAAIEQLPPMECPQHKVVSLTGNISPDGSAAFYNVIFTMADRVKARSFPMPLP
CCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
VIASSPQEREMLLNQPMIQPTLALAAEADVTFIGIGDLGPKAPLYEDGFISESELKALQK
HHCCCCHHHHHHHCCCCCCHHHHHEECCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHH
AGGIAEIVGWVFDREGRMIEGITNDRVSSASLPSREKSLVIALAMGERKLPGILAAVNRR
CCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHH
LVNGLITDERTATALLASI
HHHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA