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The map label for this gene is gbh [H]

Identifier: 13474095

GI number: 13474095

Start: 3889370

End: 3890365

Strand: Direct

Name: gbh [H]

Synonym: mlr4895

Alternate gene names: 13474095

Gene position: 3889370-3890365 (Clockwise)

Preceding gene: 13474086

Following gene: 13474096

Centisome position: 55.28

GC content: 65.56

Gene sequence:

>996_bases
ATGTTCGACCCGAAATTCCGCAAGGTCGCCGACAAGATCTTCTCCAAGAGCGGCACAAGACTGGCGCCCTATTCCGGCAT
CCCGACCTTCCTCGCCGCGCCCTATCGCGAAATCGCTGCCGAAAATCCGAATTTCGGCGACTTGCAGGTGGCCATCATCG
GCGTGCCGATGGATCTGGGCGTCACCAATCGGCCCGGTTCGCGCTTCGGGCCGAGGGCGCTGCGCGCCATCGAGCGCATC
GGCCCCTACAACCACGTGCTGGAATGCGCGCCGACGCACGAGCTTCGCGTCGCCGATATTGGCGATACGCCGTTCCGCAG
CCGCTACCGGCTCGAGACCAGCCATGAGGACATCGAGCGCCGCACCAACCAGATCGTCGATGCCGGCGTCATTCCGCTTT
CGGTCGGCGGCGACCATTCGATCAGCCATCCGATCCTGAAGGCCGTCGGCAAGAAGGCGCCGGTCGGCCTCATCCACATC
GACGCCCATTGCGACACCAGTGGCCTGTTCGACATGACCAAGTTCCACCACGGCGGCCCGTTCCGCAACGCGGTGCTCGA
CGGCGTGCTCGACCCGACGCGCACCATCCAGATCGGCATCCGCGGCTCGGCCGAATACCTCTGGGAGTTCACCTACGAGT
CCGGCATGACCGTGGTGCACGCCGAGGAGGTGACCGGTCTCGGCATTCCCGCCATCATCGAGAAGGCGCGCAAGATCGTC
GGAGACGGCCCGACCTACGTCTCCTTCGACATTGACAGCGTCGATCCGGCCTTCGCGCCGGGCACCGGCACGCCGGAAGT
CGGCGGCCTGACGACGCGCGAAGTGCTTGAGCTGCTGCGCGGCCTCAAGGGCCTCAACATCGTCGGCGGCGACGTCGTCG
AGGTGGCGCCGCAATACGACGCCACCACCAACACCGCGCATGCCGGCGCCCAGGTGTTGTTCGAGATATTGAGCCTGATG
GTGTTCAGCCCGGCCATCACGGGCAAGGGAGCCTGA

Upstream 100 bases:

>100_bases
ACGGCCGCACTGCATCAGCCCAGGAGGAGCGGATATGGGTTACGATCGCGGCAAGCTCGACGCGTTGCGTCGCAAATATG
GCGAGAGCCATGGCGGCGAG

Downstream 100 bases:

>100_bases
CACCTGAAACGAAAAGGCGGCCGCCGCGCTGGAGCCGGTAGCCGCCTCAAACAATCAAAAGCTTCCAGAAGGGGAATACC
AATGGCAATCCATTCGACAC

Product: agmatinase

Products: NA

Alternate protein names: GBase; D-arginase [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MFDPKFRKVADKIFSKSGTRLAPYSGIPTFLAAPYREIAAENPNFGDLQVAIIGVPMDLGVTNRPGSRFGPRALRAIERI
GPYNHVLECAPTHELRVADIGDTPFRSRYRLETSHEDIERRTNQIVDAGVIPLSVGGDHSISHPILKAVGKKAPVGLIHI
DAHCDTSGLFDMTKFHHGGPFRNAVLDGVLDPTRTIQIGIRGSAEYLWEFTYESGMTVVHAEEVTGLGIPAIIEKARKIV
GDGPTYVSFDIDSVDPAFAPGTGTPEVGGLTTREVLELLRGLKGLNIVGGDVVEVAPQYDATTNTAHAGAQVLFEILSLM
VFSPAITGKGA

Sequences:

>Translated_331_residues
MFDPKFRKVADKIFSKSGTRLAPYSGIPTFLAAPYREIAAENPNFGDLQVAIIGVPMDLGVTNRPGSRFGPRALRAIERI
GPYNHVLECAPTHELRVADIGDTPFRSRYRLETSHEDIERRTNQIVDAGVIPLSVGGDHSISHPILKAVGKKAPVGLIHI
DAHCDTSGLFDMTKFHHGGPFRNAVLDGVLDPTRTIQIGIRGSAEYLWEFTYESGMTVVHAEEVTGLGIPAIIEKARKIV
GDGPTYVSFDIDSVDPAFAPGTGTPEVGGLTTREVLELLRGLKGLNIVGGDVVEVAPQYDATTNTAHAGAQVLFEILSLM
VFSPAITGKGA
>Mature_331_residues
MFDPKFRKVADKIFSKSGTRLAPYSGIPTFLAAPYREIAAENPNFGDLQVAIIGVPMDLGVTNRPGSRFGPRALRAIERI
GPYNHVLECAPTHELRVADIGDTPFRSRYRLETSHEDIERRTNQIVDAGVIPLSVGGDHSISHPILKAVGKKAPVGLIHI
DAHCDTSGLFDMTKFHHGGPFRNAVLDGVLDPTRTIQIGIRGSAEYLWEFTYESGMTVVHAEEVTGLGIPAIIEKARKIV
GDGPTYVSFDIDSVDPAFAPGTGTPEVGGLTTREVLELLRGLKGLNIVGGDVVEVAPQYDATTNTAHAGAQVLFEILSLM
VFSPAITGKGA

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=277, Percent_Identity=46.5703971119134, Blast_Score=246, Evalue=1e-65,
Organism=Homo sapiens, GI10947139, Length=286, Percent_Identity=27.972027972028, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1789306, Length=265, Percent_Identity=40.377358490566, Blast_Score=183, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI71996843, Length=218, Percent_Identity=26.605504587156, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6325146, Length=222, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.7; =3.5.3.10 [H]

Molecular weight: Translated: 35574; Mature: 35574

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDPKFRKVADKIFSKSGTRLAPYSGIPTFLAAPYREIAAENPNFGDLQVAIIGVPMDLG
CCCHHHHHHHHHHHHCCCCEECCCCCCCHHHHCCHHHHHCCCCCCCCEEEEEEEEEEECC
VTNRPGSRFGPRALRAIERIGPYNHVLECAPTHELRVADIGDTPFRSRYRLETSHEDIER
CCCCCCCCCCHHHHHHHHHHCCHHHHEECCCCCCEEEEECCCCCCCCCEEECCCHHHHHH
RTNQIVDAGVIPLSVGGDHSISHPILKAVGKKAPVGLIHIDAHCDTSGLFDMTKFHHGGP
HHHHHHHCCCEEEECCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHCCCCC
FRNAVLDGVLDPTRTIQIGIRGSAEYLWEFTYESGMTVVHAEEVTGLGIPAIIEKARKIV
HHHHHHHHCCCCCEEEEEEECCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHH
GDGPTYVSFDIDSVDPAFAPGTGTPEVGGLTTREVLELLRGLKGLNIVGGDVVEVAPQYD
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCEEECCCCC
ATTNTAHAGAQVLFEILSLMVFSPAITGKGA
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MFDPKFRKVADKIFSKSGTRLAPYSGIPTFLAAPYREIAAENPNFGDLQVAIIGVPMDLG
CCCHHHHHHHHHHHHCCCCEECCCCCCCHHHHCCHHHHHCCCCCCCCEEEEEEEEEEECC
VTNRPGSRFGPRALRAIERIGPYNHVLECAPTHELRVADIGDTPFRSRYRLETSHEDIER
CCCCCCCCCCHHHHHHHHHHCCHHHHEECCCCCCEEEEECCCCCCCCCEEECCCHHHHHH
RTNQIVDAGVIPLSVGGDHSISHPILKAVGKKAPVGLIHIDAHCDTSGLFDMTKFHHGGP
HHHHHHHCCCEEEECCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHCCCCC
FRNAVLDGVLDPTRTIQIGIRGSAEYLWEFTYESGMTVVHAEEVTGLGIPAIIEKARKIV
HHHHHHHHCCCCCEEEEEEECCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHH
GDGPTYVSFDIDSVDPAFAPGTGTPEVGGLTTREVLELLRGLKGLNIVGGDVVEVAPQYD
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCEEECCCCC
ATTNTAHAGAQVLFEILSLMVFSPAITGKGA
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA