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The map label for this gene is oxaA

Identifier: 13474029

GI number: 13474029

Start: 3825747

End: 3827558

Strand: Direct

Name: oxaA

Synonym: mlr4812

Alternate gene names: 13474029

Gene position: 3825747-3827558 (Clockwise)

Preceding gene: 13474028

Following gene: 13474030

Centisome position: 54.37

GC content: 61.87

Gene sequence:

>1812_bases
ATGGAAAACAACCGGAACTTCTTCATCACCATCGCGCTGTCGGTGCTGATCCTGGCGGTATGGCAATATTTTTATGTCTT
GCCGCGCAGCGAAGCCCAGCGCGAGGCCGCCCGCGTCGAGCAGCAGCGCGTCGAGGAGCAGAAGAAGGCGGCCGAGGCCG
CCAATCCGGGTGCTGGAACACCGGCTCCGGCGCCGGGCACCATTCCCAACGCGCCCGGCGGTGACACCGTCACCGTGGCC
GGCCGCGATCAGGCGCTGGCCGCTTCCAAGCGCGTCAAGATCGACACGCCGAGCCTCGAGGGCTCGATCAACCTGACCGG
CGCGCGCCTCGACGACCTTAAGCTCAAGCACTACACCGAGACCGTCGACAAGAATTCGCCCGAGATCGAACTGCTCAACC
CGCAGGCTTTGCCCACCGGCTATTTCGCCGAGATCGGCTTCGTCGGCAACGACAAGACCGGCGCGGTGCCGGGCGCTGAA
ACGGTGTGGAATGTCGACGGCAATCCGACGCTGAGCCCGTCGACGCCGGTCACGCTGACCTACACCAACGACAAGGGCCT
GACCTTCAAGCGCACCTTCTCCGTCGACGCCAACTACATGTTCACGGTGTCGGACACGGTGCAGAATTCCGGCTCGAGCG
CGGTTTCGCTGTTCAATTACGGCCGCGTCACCCGCTACGACAAGCCGGCCGTCGCCAGCACCTATGTGCTGCATGAGGGC
CTGATCGGCTTCACTGGCACCGAAGGCCTGCAGGAACACAAATACGCGTCCATCGAGAAGGACAAGCAGTACCAGCCCGG
CAAGGCGACCGATGGCTGGCTCGGCATCACCGACAAGTATTGGGCCGTCACGCTGGTGCCGACCGAGAAGCAGCCGTTCC
AGCCGCGCTATGCCTTTTTCGAGGATGGCCGCCACCGCTACCAGTCCGACTTCCTGACCGACGCGATCAATGTCGAGGCC
GGCCAGTCGGCGACCGTCGAGACCGAGGTCTTCGCCGGCGCCAAGGAAGTCGCCAAGATCAACGCCTATGCCGAAGACCG
CCACATCAAGCGGTTCGACCTTCTGATCGACTGGGGCTGGTTCCATTTCATCACCAAGCCGATGTTCTGGCTGATCGACA
CGCTCTACAAATTCCTCGGCAATTTCGGCCTGGCGATCCTCGCCACCACCGTCATCGTCAAGGCCCTCTTCTTCCCGCTT
GCCAACAAGTCCTACGCGTCGATGGCGAACATGAAGAAGGTGCAGCCCAAGATGCTGGAGATCCGCGAGAAATACGCGGA
CGACAAGATGAAGCAGCAGCAGGCGATGATGGAGCTGTACAAGACCGAGAAGATCAATCCGCTTGCCGGCTGCTGGCCGG
TGGCGCTGCAGATCCCGGTCTTCTTCTCGCTCTACAAGGTGCTCTACATCACCATCGAGATGCGCCACGCGCCGTTCTTC
GGCTGGATCCAGGATCTGGCGGCGCCCGATCCGACGTCGCTGTTCAACCTGTTCGGCCTGATCCCGGTGACGCTGCCGCA
CATGCTGATGATCGGTGTCTGGCCGCTGATCATGGGCGTCACCATGTTCCTGCAGATGCGCATGAACCCGACGCCGCCGG
ATCCGACCCAGGCCGCGATCTTCACCTGGATGCCTGTCATCTTCACCTTCATGATGGCGGGCTTCCCGGCCGGCCTGGTC
ATCTACTGGGCCTGGAACAACATGCTGTCGATCCTGCAGCAAGGCGTGATCATGAAGCGCCAGGGCGCCAAGATCGAACT
ATGGGACAATCTGATGGCCCTGTTCAAAAAGAAACCGTCACCGGCGGAATAG

Upstream 100 bases:

>100_bases
TCATCGTCGGGCGCGATGATGCGCTGCGCGCCCCCTTCGGCCAGTTGAAGGCCGAACTCTCCCGCCGATTTCGCGGAACA
CGATAGGCCAAGGGCTCTCG

Downstream 100 bases:

>100_bases
AAACTCCTCTCTCGAAAAAGCCCGGTTCGTCCGGGCTTTTTCTTTGGGCGGATATTCGTTCACGTTCCCGTGATCGGCGA
AACTAGCGCGCCGGCAGCGG

Product: putative inner membrane protein translocase component YidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MENNRNFFITIALSVLILAVWQYFYVLPRSEAQREAARVEQQRVEEQKKAAEAANPGAGTPAPAPGTIPNAPGGDTVTVA
GRDQALAASKRVKIDTPSLEGSINLTGARLDDLKLKHYTETVDKNSPEIELLNPQALPTGYFAEIGFVGNDKTGAVPGAE
TVWNVDGNPTLSPSTPVTLTYTNDKGLTFKRTFSVDANYMFTVSDTVQNSGSSAVSLFNYGRVTRYDKPAVASTYVLHEG
LIGFTGTEGLQEHKYASIEKDKQYQPGKATDGWLGITDKYWAVTLVPTEKQPFQPRYAFFEDGRHRYQSDFLTDAINVEA
GQSATVETEVFAGAKEVAKINAYAEDRHIKRFDLLIDWGWFHFITKPMFWLIDTLYKFLGNFGLAILATTVIVKALFFPL
ANKSYASMANMKKVQPKMLEIREKYADDKMKQQQAMMELYKTEKINPLAGCWPVALQIPVFFSLYKVLYITIEMRHAPFF
GWIQDLAAPDPTSLFNLFGLIPVTLPHMLMIGVWPLIMGVTMFLQMRMNPTPPDPTQAAIFTWMPVIFTFMMAGFPAGLV
IYWAWNNMLSILQQGVIMKRQGAKIELWDNLMALFKKKPSPAE

Sequences:

>Translated_603_residues
MENNRNFFITIALSVLILAVWQYFYVLPRSEAQREAARVEQQRVEEQKKAAEAANPGAGTPAPAPGTIPNAPGGDTVTVA
GRDQALAASKRVKIDTPSLEGSINLTGARLDDLKLKHYTETVDKNSPEIELLNPQALPTGYFAEIGFVGNDKTGAVPGAE
TVWNVDGNPTLSPSTPVTLTYTNDKGLTFKRTFSVDANYMFTVSDTVQNSGSSAVSLFNYGRVTRYDKPAVASTYVLHEG
LIGFTGTEGLQEHKYASIEKDKQYQPGKATDGWLGITDKYWAVTLVPTEKQPFQPRYAFFEDGRHRYQSDFLTDAINVEA
GQSATVETEVFAGAKEVAKINAYAEDRHIKRFDLLIDWGWFHFITKPMFWLIDTLYKFLGNFGLAILATTVIVKALFFPL
ANKSYASMANMKKVQPKMLEIREKYADDKMKQQQAMMELYKTEKINPLAGCWPVALQIPVFFSLYKVLYITIEMRHAPFF
GWIQDLAAPDPTSLFNLFGLIPVTLPHMLMIGVWPLIMGVTMFLQMRMNPTPPDPTQAAIFTWMPVIFTFMMAGFPAGLV
IYWAWNNMLSILQQGVIMKRQGAKIELWDNLMALFKKKPSPAE
>Mature_603_residues
MENNRNFFITIALSVLILAVWQYFYVLPRSEAQREAARVEQQRVEEQKKAAEAANPGAGTPAPAPGTIPNAPGGDTVTVA
GRDQALAASKRVKIDTPSLEGSINLTGARLDDLKLKHYTETVDKNSPEIELLNPQALPTGYFAEIGFVGNDKTGAVPGAE
TVWNVDGNPTLSPSTPVTLTYTNDKGLTFKRTFSVDANYMFTVSDTVQNSGSSAVSLFNYGRVTRYDKPAVASTYVLHEG
LIGFTGTEGLQEHKYASIEKDKQYQPGKATDGWLGITDKYWAVTLVPTEKQPFQPRYAFFEDGRHRYQSDFLTDAINVEA
GQSATVETEVFAGAKEVAKINAYAEDRHIKRFDLLIDWGWFHFITKPMFWLIDTLYKFLGNFGLAILATTVIVKALFFPL
ANKSYASMANMKKVQPKMLEIREKYADDKMKQQQAMMELYKTEKINPLAGCWPVALQIPVFFSLYKVLYITIEMRHAPFF
GWIQDLAAPDPTSLFNLFGLIPVTLPHMLMIGVWPLIMGVTMFLQMRMNPTPPDPTQAAIFTWMPVIFTFMMAGFPAGLV
IYWAWNNMLSILQQGVIMKRQGAKIELWDNLMALFKKKPSPAE

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=529, Percent_Identity=30.6238185255198, Blast_Score=248, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_RHILO (Q98D88)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_105597.1
- GeneID:   1228258
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr4812
- NMPDR:   fig|266835.1.peg.3701
- HOGENOM:   HBG507812
- OMA:   FVTIEMR
- ProtClustDB:   PRK01318
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03593
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 67512; Mature: 67512

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xfba64e4)-; HASH(0x1194f990)-; HASH(0x127defc4)-; HASH(0x13f37574)-; HASH(0x13ab8750)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENNRNFFITIALSVLILAVWQYFYVLPRSEAQREAARVEQQRVEEQKKAAEAANPGAGT
CCCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PAPAPGTIPNAPGGDTVTVAGRDQALAASKRVKIDTPSLEGSINLTGARLDDLKLKHYTE
CCCCCCCCCCCCCCCEEEEECCCHHHHCCCEEEEECCCCCCEEEEECCCCCCCHHHHHHH
TVDKNSPEIELLNPQALPTGYFAEIGFVGNDKTGAVPGAETVWNVDGNPTLSPSTPVTLT
HHCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEE
YTNDKGLTFKRTFSVDANYMFTVSDTVQNSGSSAVSLFNYGRVTRYDKPAVASTYVLHEG
EECCCCCEEEEEEECCCCEEEEEEHHHHCCCCCEEEEHHCCCCCCCCCCCHHHHHHHHCC
LIGFTGTEGLQEHKYASIEKDKQYQPGKATDGWLGITDKYWAVTLVPTEKQPFQPRYAFF
CCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCEECCCCEEEEEEEECCCCCCCCCHHHH
EDGRHRYQSDFLTDAINVEAGQSATVETEVFAGAKEVAKINAYAEDRHIKRFDLLIDWGW
HCHHHHHHHHHHHHHHCCCCCCCCEEEHHHHCCHHHHHHHHHHHHCCCCEEEEEEEECHH
FHFITKPMFWLIDTLYKFLGNFGLAILATTVIVKALFFPLANKSYASMANMKKVQPKMLE
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHH
IREKYADDKMKQQQAMMELYKTEKINPLAGCWPVALQIPVFFSLYKVLYITIEMRHAPFF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCHH
GWIQDLAAPDPTSLFNLFGLIPVTLPHMLMIGVWPLIMGVTMFLQMRMNPTPPDPTQAAI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
FTWMPVIFTFMMAGFPAGLVIYWAWNNMLSILQQGVIMKRQGAKIELWDNLMALFKKKPS
HHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHCCCEEECCCCEEEHHHHHHHHHHCCCC
PAE
CCH
>Mature Secondary Structure
MENNRNFFITIALSVLILAVWQYFYVLPRSEAQREAARVEQQRVEEQKKAAEAANPGAGT
CCCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PAPAPGTIPNAPGGDTVTVAGRDQALAASKRVKIDTPSLEGSINLTGARLDDLKLKHYTE
CCCCCCCCCCCCCCCEEEEECCCHHHHCCCEEEEECCCCCCEEEEECCCCCCCHHHHHHH
TVDKNSPEIELLNPQALPTGYFAEIGFVGNDKTGAVPGAETVWNVDGNPTLSPSTPVTLT
HHCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEE
YTNDKGLTFKRTFSVDANYMFTVSDTVQNSGSSAVSLFNYGRVTRYDKPAVASTYVLHEG
EECCCCCEEEEEEECCCCEEEEEEHHHHCCCCCEEEEHHCCCCCCCCCCCHHHHHHHHCC
LIGFTGTEGLQEHKYASIEKDKQYQPGKATDGWLGITDKYWAVTLVPTEKQPFQPRYAFF
CCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCEECCCCEEEEEEEECCCCCCCCCHHHH
EDGRHRYQSDFLTDAINVEAGQSATVETEVFAGAKEVAKINAYAEDRHIKRFDLLIDWGW
HCHHHHHHHHHHHHHHCCCCCCCCEEEHHHHCCHHHHHHHHHHHHCCCCEEEEEEEECHH
FHFITKPMFWLIDTLYKFLGNFGLAILATTVIVKALFFPLANKSYASMANMKKVQPKMLE
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHH
IREKYADDKMKQQQAMMELYKTEKINPLAGCWPVALQIPVFFSLYKVLYITIEMRHAPFF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCHH
GWIQDLAAPDPTSLFNLFGLIPVTLPHMLMIGVWPLIMGVTMFLQMRMNPTPPDPTQAAI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
FTWMPVIFTFMMAGFPAGLVIYWAWNNMLSILQQGVIMKRQGAKIELWDNLMALFKKKPS
HHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHCCCEEECCCCEEEHHHHHHHHHHCCCC
PAE
CCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11214968