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The map label for this gene is 13474023

Identifier: 13474023

GI number: 13474023

Start: 3821564

End: 3821986

Strand: Reverse

Name: 13474023

Synonym: mll4803

Alternate gene names: NA

Gene position: 3821986-3821564 (Counterclockwise)

Preceding gene: 13474026

Following gene: 13474022

Centisome position: 54.32

GC content: 63.59

Gene sequence:

>423_bases
GTGCATGGGCGCCATGAAGCTGATAGCCGCTCCATCGGCTACGCTGTCCGCGAGAACCCTGGAAAGCTCCCCCAGCCTTT
TTCGATGGCGGTAGCGTCGAGTTCAATTATCAGCGTTTCCATGTATGGCGGTTCCTTAAGCCATGGCGATAATGTAGCGG
GCCGATTGTTCGCCGGTCTCAAAGGAAGAGGCGGCGTGCGCTTTCCGATCGGGGTCGACCGCCGCATCAAGGGCGCCGGC
GATGTCGGCGAACACAAGACCTCGATGCTGCAGGACCTGGAACGCGGCCGGCCGATGGAAATCGACGCGCTGGTGAGCGC
GGTGCAGGAGCTTGGTCGGCTGGCGGACAAGCCGACGCCGACCATAGATGCGGTGCTGGCGCTGGTGCGGCGGCTGGCGG
TGGAGCGCGGATGTTACGGGTGA

Upstream 100 bases:

>100_bases
CGACGATCTCGCCGTCCCGCTCGGCGCCGAAAAGCACTCTACGTCCTGCGGCGACCTCACGCTGGACATCGCCTGACCAG
AACCGAGCCGCGTCCTCGTA

Downstream 100 bases:

>100_bases
TGCGGCACGGCGGGCCAAACCTTGACGCGCTCATGCCCCGCCCAAAATATCGTGGGCCGCCCTTGTTGCCGATCCGGGAG
GGGCGTGCCGAAACAGATAT

Product: hypothetical protein

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MHGRHEADSRSIGYAVRENPGKLPQPFSMAVASSSIISVSMYGGSLSHGDNVAGRLFAGLKGRGGVRFPIGVDRRIKGAG
DVGEHKTSMLQDLERGRPMEIDALVSAVQELGRLADKPTPTIDAVLALVRRLAVERGCYG

Sequences:

>Translated_140_residues
MHGRHEADSRSIGYAVRENPGKLPQPFSMAVASSSIISVSMYGGSLSHGDNVAGRLFAGLKGRGGVRFPIGVDRRIKGAG
DVGEHKTSMLQDLERGRPMEIDALVSAVQELGRLADKPTPTIDAVLALVRRLAVERGCYG
>Mature_140_residues
MHGRHEADSRSIGYAVRENPGKLPQPFSMAVASSSIISVSMYGGSLSHGDNVAGRLFAGLKGRGGVRFPIGVDRRIKGAG
DVGEHKTSMLQDLERGRPMEIDALVSAVQELGRLADKPTPTIDAVLALVRRLAVERGCYG

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 14897; Mature: 14897

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGRHEADSRSIGYAVRENPGKLPQPFSMAVASSSIISVSMYGGSLSHGDNVAGRLFAGL
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHCC
KGRGGVRFPIGVDRRIKGAGDVGEHKTSMLQDLERGRPMEIDALVSAVQELGRLADKPTP
CCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCC
TIDAVLALVRRLAVERGCYG
HHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHGRHEADSRSIGYAVRENPGKLPQPFSMAVASSSIISVSMYGGSLSHGDNVAGRLFAGL
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHCC
KGRGGVRFPIGVDRRIKGAGDVGEHKTSMLQDLERGRPMEIDALVSAVQELGRLADKPTP
CCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCC
TIDAVLALVRRLAVERGCYG
HHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]