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The map label for this gene is ntrB [H]

Identifier: 13474026

GI number: 13474026

Start: 3823462

End: 3824553

Strand: Reverse

Name: ntrB [H]

Synonym: mll4807

Alternate gene names: 13474026

Gene position: 3824553-3823462 (Counterclockwise)

Preceding gene: 13474033

Following gene: 13474023

Centisome position: 54.36

GC content: 66.67

Gene sequence:

>1092_bases
ATGACCGGCGCGCTCGACACGCTGTTCTTCGGCGGCGACCGGATGCTGCGCGTCTTCGGACCGGTCGGCGACAGCGACAA
GGAATTCGAGCTGATCATGCCGGATTACTCGCTGCGCAAGGCCATGCTCATCTATTCGCGCAATGTCGCCTTCGTGTCGC
TGCTGATCTCGCTGTTCACCGCCATGCTGGTCTATGCCGCGATCGACCTGATCATGATCGGGCCGATCCGCACCATGACG
CGCTCGATGCTGTCCTTCTCCGAAGCGCCCGACGACCCCGGGCGCATCATCCGTCCCGCCGCCCGCTCCGATGAAATCGG
CGTTGCCGAACGCGAGCTGTCGCAGATGCAGGAGCGGCTGCAAAAGATGCTTTCCGAGCAGAAACACCTTGCCGATCTCG
GCCTGGCGGTCTCCAAGATCAACCATGACATGCGCAACATCCTGGCCTCGGCGCAGCTGATGTCGGACCGCCTGCGCCAG
GTCAGGGACCCGACCGTGCAGGCCTTTGCGCCGAAGCTTTTGCGGGCGCTCGACCGCGCCGTCTCCTATTCCGAAGGCGT
GCTTCACTATGGCCGCACGCAGGAGCCGCCGCCTTCGCGCCGCCGGGTGCGGCTGCGCCAGCTGGTCGAGGACGTGCACG
GTCTGCTCGACATCGAGGAAGGCATCGAGTTCATCAACGCCGTCGAGACGGCTTTCGAGGTGGACGCCGATTCCGACCAG
CTGTTTAGGGTGCTCACCAATCTGTGCCGCAACTCGGTGCAAGCGATGGCGGCCGACACAGAGAGCGCGGTGGTACGGCG
GCTCGCCGTATCCGCCGAGCGCATGGGCAGCGTCAGCCGCATCGCCGTCACCGATACCGGCCCCGGCCTGCCGCCGAAGG
CGCGCGAAAACTTGTTCGCGGCGTTCCGCGGCTCGGCGCGCAGCGGCGGCACCGGCCTTGGCCTGGCGATCGCCCACGAA
CTGATCCGAGCGCATGGCGGCACGGTGGAACTGGTCGAATCGATTGGCGGGCGCACCACTTTCGCCGTCACCATCCCCGA
CCAACCGGTGCGGCTCGACCAGGCCCGCGGCAGTCTGCGCCGCCCGGCGTGA

Upstream 100 bases:

>100_bases
GGTGCGCGATGGCGGCGTCTCGCGGCTTCTGGTGGTGGCGGACATGCCGCCGCAGGTCGACGAGCATATCGACCTCGCCA
GCGTCGGCATGATCAAAGGC

Downstream 100 bases:

>100_bases
CGGCCTCGGTGCAATTTTCCCAAGGGCTCTACCCTTCGGTCCGCACGCTTTCCAAGACCTTTGCCGAGACTTTTTCCCCG
CTCGGCCTGAACGAGACCTG

Product: histidine protein kinase sensor for nitrogen regulator II, NRII (GlnG)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MTGALDTLFFGGDRMLRVFGPVGDSDKEFELIMPDYSLRKAMLIYSRNVAFVSLLISLFTAMLVYAAIDLIMIGPIRTMT
RSMLSFSEAPDDPGRIIRPAARSDEIGVAERELSQMQERLQKMLSEQKHLADLGLAVSKINHDMRNILASAQLMSDRLRQ
VRDPTVQAFAPKLLRALDRAVSYSEGVLHYGRTQEPPPSRRRVRLRQLVEDVHGLLDIEEGIEFINAVETAFEVDADSDQ
LFRVLTNLCRNSVQAMAADTESAVVRRLAVSAERMGSVSRIAVTDTGPGLPPKARENLFAAFRGSARSGGTGLGLAIAHE
LIRAHGGTVELVESIGGRTTFAVTIPDQPVRLDQARGSLRRPA

Sequences:

>Translated_363_residues
MTGALDTLFFGGDRMLRVFGPVGDSDKEFELIMPDYSLRKAMLIYSRNVAFVSLLISLFTAMLVYAAIDLIMIGPIRTMT
RSMLSFSEAPDDPGRIIRPAARSDEIGVAERELSQMQERLQKMLSEQKHLADLGLAVSKINHDMRNILASAQLMSDRLRQ
VRDPTVQAFAPKLLRALDRAVSYSEGVLHYGRTQEPPPSRRRVRLRQLVEDVHGLLDIEEGIEFINAVETAFEVDADSDQ
LFRVLTNLCRNSVQAMAADTESAVVRRLAVSAERMGSVSRIAVTDTGPGLPPKARENLFAAFRGSARSGGTGLGLAIAHE
LIRAHGGTVELVESIGGRTTFAVTIPDQPVRLDQARGSLRRPA
>Mature_362_residues
TGALDTLFFGGDRMLRVFGPVGDSDKEFELIMPDYSLRKAMLIYSRNVAFVSLLISLFTAMLVYAAIDLIMIGPIRTMTR
SMLSFSEAPDDPGRIIRPAARSDEIGVAERELSQMQERLQKMLSEQKHLADLGLAVSKINHDMRNILASAQLMSDRLRQV
RDPTVQAFAPKLLRALDRAVSYSEGVLHYGRTQEPPPSRRRVRLRQLVEDVHGLLDIEEGIEFINAVETAFEVDADSDQL
FRVLTNLCRNSVQAMAADTESAVVRRLAVSAERMGSVSRIAVTDTGPGLPPKARENLFAAFRGSARSGGTGLGLAIAHEL
IRAHGGTVELVESIGGRTTFAVTIPDQPVRLDQARGSLRRPA

Specific function: NtrB acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC. In nitrogen limitation ntrB activates ntrC by phosphorylating it, while in nitrogen excess ntrC is dephosphorylated and consequently inactiva

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790300, Length=249, Percent_Identity=31.3253012048193, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790436, Length=258, Percent_Identity=27.1317829457364, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788549, Length=234, Percent_Identity=26.0683760683761, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786912, Length=118, Percent_Identity=35.5932203389831, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39927; Mature: 39795

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGALDTLFFGGDRMLRVFGPVGDSDKEFELIMPDYSLRKAMLIYSRNVAFVSLLISLFT
CCCCHHHHHCCCCHHEEEECCCCCCCCCEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHH
AMLVYAAIDLIMIGPIRTMTRSMLSFSEAPDDPGRIIRPAARSDEIGVAERELSQMQERL
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHH
QKMLSEQKHLADLGLAVSKINHDMRNILASAQLMSDRLRQVRDPTVQAFAPKLLRALDRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VSYSEGVLHYGRTQEPPPSRRRVRLRQLVEDVHGLLDIEEGIEFINAVETAFEVDADSDQ
HHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LFRVLTNLCRNSVQAMAADTESAVVRRLAVSAERMGSVSRIAVTDTGPGLPPKARENLFA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHH
AFRGSARSGGTGLGLAIAHELIRAHGGTVELVESIGGRTTFAVTIPDQPVRLDQARGSLR
HHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEECCCCCCHHHHHCCCCC
RPA
CCC
>Mature Secondary Structure 
TGALDTLFFGGDRMLRVFGPVGDSDKEFELIMPDYSLRKAMLIYSRNVAFVSLLISLFT
CCCHHHHHCCCCHHEEEECCCCCCCCCEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHH
AMLVYAAIDLIMIGPIRTMTRSMLSFSEAPDDPGRIIRPAARSDEIGVAERELSQMQERL
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHH
QKMLSEQKHLADLGLAVSKINHDMRNILASAQLMSDRLRQVRDPTVQAFAPKLLRALDRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VSYSEGVLHYGRTQEPPPSRRRVRLRQLVEDVHGLLDIEEGIEFINAVETAFEVDADSDQ
HHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LFRVLTNLCRNSVQAMAADTESAVVRRLAVSAERMGSVSRIAVTDTGPGLPPKARENLFA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHH
AFRGSARSGGTGLGLAIAHELIRAHGGTVELVESIGGRTTFAVTIPDQPVRLDQARGSLR
HHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEECCCCCCHHHHHCCCCC
RPA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2574025 [H]