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The map label for this gene is ycgM [C]

Identifier: 13474005

GI number: 13474005

Start: 3798995

End: 3799840

Strand: Reverse

Name: ycgM [C]

Synonym: mll4780

Alternate gene names: 13474005

Gene position: 3799840-3798995 (Counterclockwise)

Preceding gene: 13474006

Following gene: 13473997

Centisome position: 54.01

GC content: 63.83

Gene sequence:

>846_bases
ATGAAACTGCTGCGCTATGGCGAGGTGGGGAGCGAACGTCCCGGCCTGCTCGATGCGGATGGAACGATCCGCGATCTCTC
CGCCCATGTCGCCGACATTGCCGGCACCACGCTTCATCCGGCCTCGCTGGAGATGCTGGGCAAGCTTGATCCGAAGTCGC
TGCCGGCGGTTTCCGGCAAGCCTCGCCTCGGCGCCTGCGTCGCCGGCACCGGAAAATTCATCTGCATCGGCCTCAACTAC
TCCGACCACGCCGCCGAAACCGGTGCCACCGTGCCGCCGGAGCCGATCATCTTCATGAAGGCGAGCTCGGCCATTGTCGG
CCCGGACGACGACGTGCTGATCCCGCGCGGTTCCGAAAAGACCGACTGGGAAGTCGAGCTCGCAGTGGTCATCGGCAAGA
CGGCAAAGTATGTCAGCGAAGCCGACGCGCTGGATTATGTCGCCGGCTATGCCGTTGCGCATGACGTCTCCGAGCGCGCC
TTCCAGGCGGAGCGGCAAGGCCAGTGGACCAAGGGCAAGAGCTGCGACACGTTTGGCCCGACCGGCCCGTGGCTGGTGAC
CAAGGACGAAGTCGCCGACCCGCAGAACCTGAAGATGTGGCTGACCGTCAACGGCAAGACCATGCAGAACGGCTCGACCA
AGACCATGGTCTACGGCGTCAAATATCTGGTGTCCTATCTCAGCCAGTTCATGTCGCTGCACCCCGGCGACATTATTTCG
ACAGGCACCCCGCCCGGCGTGGGCCTCGGCATGAAGCCGCCAGTATTCCTCAGGGCCGGCGATGTGGTGGAACTGGGCAT
CGAGGGCCTCGGCCAGCAGAAGCAGACGTTCAAGGCTGACGTGTAG

Upstream 100 bases:

>100_bases
TCAGGTCGATGGGTACGGTCCGCCCGGCTCCTCGGGGAGCCATCGTCTCGACGGAGAGTTTGCAAGAGGCCGCGAGGCCG
CAACCAGGAGAAGGATTTAG

Downstream 100 bases:

>100_bases
CGGTTAGCTTTTCCTTCTCCCCGTCACTATACGGGGAGAAGGTACCGGCAGGCGGATGAGGGGCGGCGTCAACCTTGCCC
TACTTCAGCACTTTCCCGTC

Product: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MKLLRYGEVGSERPGLLDADGTIRDLSAHVADIAGTTLHPASLEMLGKLDPKSLPAVSGKPRLGACVAGTGKFICIGLNY
SDHAAETGATVPPEPIIFMKASSAIVGPDDDVLIPRGSEKTDWEVELAVVIGKTAKYVSEADALDYVAGYAVAHDVSERA
FQAERQGQWTKGKSCDTFGPTGPWLVTKDEVADPQNLKMWLTVNGKTMQNGSTKTMVYGVKYLVSYLSQFMSLHPGDIIS
TGTPPGVGLGMKPPVFLRAGDVVELGIEGLGQQKQTFKADV

Sequences:

>Translated_281_residues
MKLLRYGEVGSERPGLLDADGTIRDLSAHVADIAGTTLHPASLEMLGKLDPKSLPAVSGKPRLGACVAGTGKFICIGLNY
SDHAAETGATVPPEPIIFMKASSAIVGPDDDVLIPRGSEKTDWEVELAVVIGKTAKYVSEADALDYVAGYAVAHDVSERA
FQAERQGQWTKGKSCDTFGPTGPWLVTKDEVADPQNLKMWLTVNGKTMQNGSTKTMVYGVKYLVSYLSQFMSLHPGDIIS
TGTPPGVGLGMKPPVFLRAGDVVELGIEGLGQQKQTFKADV
>Mature_281_residues
MKLLRYGEVGSERPGLLDADGTIRDLSAHVADIAGTTLHPASLEMLGKLDPKSLPAVSGKPRLGACVAGTGKFICIGLNY
SDHAAETGATVPPEPIIFMKASSAIVGPDDDVLIPRGSEKTDWEVELAVVIGKTAKYVSEADALDYVAGYAVAHDVSERA
FQAERQGQWTKGKSCDTFGPTGPWLVTKDEVADPQNLKMWLTVNGKTMQNGSTKTMVYGVKYLVSYLSQFMSLHPGDIIS
TGTPPGVGLGMKPPVFLRAGDVVELGIEGLGQQKQTFKADV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=208, Percent_Identity=54.8076923076923, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI40786394, Length=208, Percent_Identity=53.8461538461538, Blast_Score=231, Evalue=6e-61,
Organism=Homo sapiens, GI66348062, Length=204, Percent_Identity=40.1960784313725, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI13654274, Length=212, Percent_Identity=39.622641509434, Blast_Score=152, Evalue=2e-37,
Organism=Homo sapiens, GI215422413, Length=202, Percent_Identity=40.0990099009901, Blast_Score=152, Evalue=4e-37,
Organism=Escherichia coli, GI1787428, Length=201, Percent_Identity=35.8208955223881, Blast_Score=131, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17557057, Length=199, Percent_Identity=36.1809045226131, Blast_Score=144, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6324161, Length=217, Percent_Identity=32.258064516129, Blast_Score=105, Evalue=6e-24,
Organism=Drosophila melanogaster, GI28572127, Length=285, Percent_Identity=43.1578947368421, Blast_Score=206, Evalue=1e-53,
Organism=Drosophila melanogaster, GI28571789, Length=212, Percent_Identity=38.6792452830189, Blast_Score=144, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24663695, Length=211, Percent_Identity=36.0189573459716, Blast_Score=144, Evalue=8e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 29849; Mature: 29849

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLRYGEVGSERPGLLDADGTIRDLSAHVADIAGTTLHPASLEMLGKLDPKSLPAVSGK
CCCEECCCCCCCCCCEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCC
PRLGACVAGTGKFICIGLNYSDHAAETGATVPPEPIIFMKASSAIVGPDDDVLIPRGSEK
CCCCEEEECCCCEEEEECCCCHHHHCCCCCCCCCCEEEEECCCEEECCCCCEEEECCCCC
TDWEVELAVVIGKTAKYVSEADALDYVAGYAVAHDVSERAFQAERQGQWTKGKSCDTFGP
CCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
TGPWLVTKDEVADPQNLKMWLTVNGKTMQNGSTKTMVYGVKYLVSYLSQFMSLHPGDIIS
CCCEEEEHHCCCCCCCCEEEEEECCEEECCCCCEEHHHHHHHHHHHHHHHHHCCCCCEEE
TGTPPGVGLGMKPPVFLRAGDVVELGIEGLGQQKQTFKADV
CCCCCCCCCCCCCCEEEECCCEEEECHHCCCCCHHHHCCCC
>Mature Secondary Structure
MKLLRYGEVGSERPGLLDADGTIRDLSAHVADIAGTTLHPASLEMLGKLDPKSLPAVSGK
CCCEECCCCCCCCCCEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCC
PRLGACVAGTGKFICIGLNYSDHAAETGATVPPEPIIFMKASSAIVGPDDDVLIPRGSEK
CCCCEEEECCCCEEEEECCCCHHHHCCCCCCCCCCEEEEECCCEEECCCCCEEEECCCCC
TDWEVELAVVIGKTAKYVSEADALDYVAGYAVAHDVSERAFQAERQGQWTKGKSCDTFGP
CCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
TGPWLVTKDEVADPQNLKMWLTVNGKTMQNGSTKTMVYGVKYLVSYLSQFMSLHPGDIIS
CCCEEEEHHCCCCCCCCEEEEEECCEEECCCCCEEHHHHHHHHHHHHHHHHHCCCCCEEE
TGTPPGVGLGMKPPVFLRAGDVVELGIEGLGQQKQTFKADV
CCCCCCCCCCCCCCEEEECCCEEEECHHCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA