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The map label for this gene is hyuA [H]

Identifier: 13473912

GI number: 13473912

Start: 3696136

End: 3698178

Strand: Direct

Name: hyuA [H]

Synonym: mlr4662

Alternate gene names: 13473912

Gene position: 3696136-3698178 (Clockwise)

Preceding gene: 13473911

Following gene: 13473913

Centisome position: 52.53

GC content: 70.0

Gene sequence:

>2043_bases
ATGACCGCCAAGACCAAGCCAAAACCCCTGTTCCTCGGCATCGACACCGGTGGCACCTACACCGATGCCGTGCTGTGGTC
CGAGACGGAAGGCCCGCAGCACGGGCCGAACAAGGGCAAGGTGCTGGCCAAGGCCAAGGCGCTGACGACACGGCATGATC
TCGCCGTCGGCATTTCCGGCGCGGTCGACGCGGTGCTGGAAAAATCCGGCACCGATCCGGCCGCGATCAAGCTGGTCTCG
ATGTCGACGACGCTCGCCACCAATGCGCTGGTCGAGGGCCAGGGTGGCCGTGTCGCGCTCGTCATGATCGGCTTTTCCGA
AGTCGACCTCGCCCGCGACGGGTTGAAGACCGCGCTCGGCACCGATCCGGTGGTGTTTTGCCCGGGCGGCCACGATGTCC
ACGGCAATGCCGCCAGGCTTGATTTGTCAGGGCTGGAAGCGGCCCTGCCGGAACTCGGCGCCTCGGTGTCCGGCTTTGCC
GTCTGCGCCTATTTCGCCACCCGCAACCCGGCGCATGAGATCGCCGCCCGCGAACTGATCCGTGACAGAACCGGCCTGCC
GGTCACCGCGAGCCACGAACTGTCAGCCAAGCTCGGCGGCCCGCGCCGGGCGCTGACCACGCTGCTCAATGCCCGGCTGA
TTTCGATGATCGACCGGCTGGTGGCCGCGACAGAAGGGTTTTTGCAAGCCCGCAACATCGCCGCCCCCCTGATGGTGGTG
CGCGGCGACGGCGCGCTGGTCTCGGCGGCGTTCGCTCGCCAGCGGCCGATCGAGACCATCCTCTCCGGTCCGGCGGCCAG
CCTGGTCGGCGCCCGTCACATGACCGGGCTCGAGAATGCCGTGGTCTCCGACATTGGCGGCACCACCACCGACGTCGCCG
TGCTCGACCAGGGCCGGCCGCGGCTTGATCCCGAGGGCGCCACCGTCGGCGGCTTCCGCACCATGGTCGAGGCCGTCGCC
ATGCGCACTTTCGGCCTCGGCGGCGATTCCGAAGTGGCGCTGGAAGATGGCGCGCTCAACCCAAAAATCCTGCTTGGGCC
ACGCCGCCTGGTGCCGCTGGCGCTGGCCGGCATGGCGCATGGCGAGGCCGTCAAATCGGAACTCGAACGCCAGCTGCGTT
CGCCCAATCCCGGCCGCATGGATGGCCGCTTCGCCGTGCGCACCGGCGTGCCGGACAGGCTCGCCGCCGGGCTGACCGCG
CCGGAAGCGCGGCTCTACGAGGCGATCGGCGCGACGCCGCTCACCCTCGACAGGCTGCTGACGTCGAATGCCCAGAACGC
CACCTTGAACCGGCTGGTCTCGCGCGGGCTGGTGCATATCTGCGGCTTCACCCCGTCGGACGCGGCACACGTGCTGGGCA
AGCAGGCCAATTGGGATGCCGCCACCGCCCGCCTCGGCGCCGAGCTGTTCGCCCGCAAGCGCGATGGCCGTGGCCAGCCC
ATCGCCGCGTCGCCGGAGGTGATCTCGGAGCGCGTGCTGGTGACGCTGACGCGCTGGTCGGCCGAATACATCCTCGAAAC
CGCCTTCGCCGAGGACGGGCTCGATGGCGCCGCGACGGTGGCGCACGCGCTGGTGCAGCGCGCCGTCGATGCCCATCCCG
GCATCGCCCGGCTGAGCGTCGCGCTCGACCGCCCGGTCATCGGCCTCGGCGCCTCGGCGCCGCTGCACTATGCCGGCCTG
GCGCCTTTGGTCGGCAATGGCTGCGTGGTGCCCGAGGACACCGATGTCGCCAACGCGCTCGGCGCCGTCGTCGGCCAGGT
CAGGGTCTCGGCCGAGGCGCGGGTCAGCCAGCCCAGGGAAGGGTTGTTCCGCCTTGCTTCCGGAGGAACAGTGCGCGATT
TCCTCGACGAGGCTGCGGCGATCGCCGCCGCCGAGGCCGATGTGCGGGCCATCGTCGCCGAGCGCGCCCGGGACGCCGGC
ACCGACAGCGCCGAAATCGACGTCGCGACCGAATTCAAGGTTTCCACGGTCGAAGCCCAGCGCATGTTCATCGAGGCGCA
TGTGGTGGCGGTGGCCTCGGGACGGCCAAGGATCGCGGTGTAG

Upstream 100 bases:

>100_bases
ATTGCGGTCATCGCGTGTTGGCCCAGCGCTCGCGGCTTTATCGGCTGGCCGCGATAGGCTAAGGGCGGGGAAGCAAAATT
CCCCACCGCCCGGACCGCCA

Downstream 100 bases:

>100_bases
ATTCAGGTGAGGCCGGCCTGCAAATGGCGGCGTCCTGGGCTTCCCCGTTCTACTGCGTCGCAGTAGAACTGAGCTCACGT
ACCCAAAAGTACGCTCCGCT

Product: hydantoinase

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 680; Mature: 679

Protein sequence:

>680_residues
MTAKTKPKPLFLGIDTGGTYTDAVLWSETEGPQHGPNKGKVLAKAKALTTRHDLAVGISGAVDAVLEKSGTDPAAIKLVS
MSTTLATNALVEGQGGRVALVMIGFSEVDLARDGLKTALGTDPVVFCPGGHDVHGNAARLDLSGLEAALPELGASVSGFA
VCAYFATRNPAHEIAARELIRDRTGLPVTASHELSAKLGGPRRALTTLLNARLISMIDRLVAATEGFLQARNIAAPLMVV
RGDGALVSAAFARQRPIETILSGPAASLVGARHMTGLENAVVSDIGGTTTDVAVLDQGRPRLDPEGATVGGFRTMVEAVA
MRTFGLGGDSEVALEDGALNPKILLGPRRLVPLALAGMAHGEAVKSELERQLRSPNPGRMDGRFAVRTGVPDRLAAGLTA
PEARLYEAIGATPLTLDRLLTSNAQNATLNRLVSRGLVHICGFTPSDAAHVLGKQANWDAATARLGAELFARKRDGRGQP
IAASPEVISERVLVTLTRWSAEYILETAFAEDGLDGAATVAHALVQRAVDAHPGIARLSVALDRPVIGLGASAPLHYAGL
APLVGNGCVVPEDTDVANALGAVVGQVRVSAEARVSQPREGLFRLASGGTVRDFLDEAAAIAAAEADVRAIVAERARDAG
TDSAEIDVATEFKVSTVEAQRMFIEAHVVAVASGRPRIAV

Sequences:

>Translated_680_residues
MTAKTKPKPLFLGIDTGGTYTDAVLWSETEGPQHGPNKGKVLAKAKALTTRHDLAVGISGAVDAVLEKSGTDPAAIKLVS
MSTTLATNALVEGQGGRVALVMIGFSEVDLARDGLKTALGTDPVVFCPGGHDVHGNAARLDLSGLEAALPELGASVSGFA
VCAYFATRNPAHEIAARELIRDRTGLPVTASHELSAKLGGPRRALTTLLNARLISMIDRLVAATEGFLQARNIAAPLMVV
RGDGALVSAAFARQRPIETILSGPAASLVGARHMTGLENAVVSDIGGTTTDVAVLDQGRPRLDPEGATVGGFRTMVEAVA
MRTFGLGGDSEVALEDGALNPKILLGPRRLVPLALAGMAHGEAVKSELERQLRSPNPGRMDGRFAVRTGVPDRLAAGLTA
PEARLYEAIGATPLTLDRLLTSNAQNATLNRLVSRGLVHICGFTPSDAAHVLGKQANWDAATARLGAELFARKRDGRGQP
IAASPEVISERVLVTLTRWSAEYILETAFAEDGLDGAATVAHALVQRAVDAHPGIARLSVALDRPVIGLGASAPLHYAGL
APLVGNGCVVPEDTDVANALGAVVGQVRVSAEARVSQPREGLFRLASGGTVRDFLDEAAAIAAAEADVRAIVAERARDAG
TDSAEIDVATEFKVSTVEAQRMFIEAHVVAVASGRPRIAV
>Mature_679_residues
TAKTKPKPLFLGIDTGGTYTDAVLWSETEGPQHGPNKGKVLAKAKALTTRHDLAVGISGAVDAVLEKSGTDPAAIKLVSM
STTLATNALVEGQGGRVALVMIGFSEVDLARDGLKTALGTDPVVFCPGGHDVHGNAARLDLSGLEAALPELGASVSGFAV
CAYFATRNPAHEIAARELIRDRTGLPVTASHELSAKLGGPRRALTTLLNARLISMIDRLVAATEGFLQARNIAAPLMVVR
GDGALVSAAFARQRPIETILSGPAASLVGARHMTGLENAVVSDIGGTTTDVAVLDQGRPRLDPEGATVGGFRTMVEAVAM
RTFGLGGDSEVALEDGALNPKILLGPRRLVPLALAGMAHGEAVKSELERQLRSPNPGRMDGRFAVRTGVPDRLAAGLTAP
EARLYEAIGATPLTLDRLLTSNAQNATLNRLVSRGLVHICGFTPSDAAHVLGKQANWDAATARLGAELFARKRDGRGQPI
AASPEVISERVLVTLTRWSAEYILETAFAEDGLDGAATVAHALVQRAVDAHPGIARLSVALDRPVIGLGASAPLHYAGLA
PLVGNGCVVPEDTDVANALGAVVGQVRVSAEARVSQPREGLFRLASGGTVRDFLDEAAAIAAAEADVRAIVAERARDAGT
DSAEIDVATEFKVSTVEAQRMFIEAHVVAVASGRPRIAV

Specific function: HyuA and hyuB convert D- and L-substituted hydantoins to corresponding N-carbamyl-amino acids [H]

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: NA

Molecular weight: Translated: 70541; Mature: 70410

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00024 HEMOPEXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKTKPKPLFLGIDTGGTYTDAVLWSETEGPQHGPNKGKVLAKAKALTTRHDLAVGISG
CCCCCCCCEEEEEECCCCCEECEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHEEECCH
AVDAVLEKSGTDPAAIKLVSMSTTLATNALVEGQGGRVALVMIGFSEVDLARDGLKTALG
HHHHHHHCCCCCHHHEEEEEEHHHHHHHHEEECCCCEEEEEEEECCHHHHHHHHHHHHCC
TDPVVFCPGGHDVHGNAARLDLSGLEAALPELGASVSGFAVCAYFATRNPAHEIAARELI
CCCEEECCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCHHHHEEHHHCCCHHHHHHHHHHH
RDRTGLPVTASHELSAKLGGPRRALTTLLNARLISMIDRLVAATEGFLQARNIAAPLMVV
HHCCCCCEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
RGDGALVSAAFARQRPIETILSGPAASLVGARHMTGLENAVVSDIGGTTTDVAVLDQGRP
ECCCCCHHHHHHHCCCHHHHHCCCHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCCC
RLDPEGATVGGFRTMVEAVAMRTFGLGGDSEVALEDGALNPKILLGPRRLVPLALAGMAH
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEECCCHHHHHHHHHCCC
GEAVKSELERQLRSPNPGRMDGRFAVRTGVPDRLAAGLTAPEARLYEAIGATPLTLDRLL
HHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHCCCCCHHHHHHHHCCCCHHHHHHH
TSNAQNATLNRLVSRGLVHICGFTPSDAAHVLGKQANWDAATARLGAELFARKRDGRGQP
HCCCCHHHHHHHHHCCCEEEECCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCC
IAASPEVISERVLVTLTRWSAEYILETAFAEDGLDGAATVAHALVQRAVDAHPGIARLSV
CCCCHHHHHCCEEEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEE
ALDRPVIGLGASAPLHYAGLAPLVGNGCVVPEDTDVANALGAVVGQVRVSAEARVSQPRE
ECCCCEEECCCCCCCHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCHH
GLFRLASGGTVRDFLDEAAAIAAAEADVRAIVAERARDAGTDSAEIDVATEFKVSTVEAQ
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEHHHHH
RMFIEAHVVAVASGRPRIAV
HHEEEEEEEEEECCCCCCCC
>Mature Secondary Structure 
TAKTKPKPLFLGIDTGGTYTDAVLWSETEGPQHGPNKGKVLAKAKALTTRHDLAVGISG
CCCCCCCEEEEEECCCCCEECEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHEEECCH
AVDAVLEKSGTDPAAIKLVSMSTTLATNALVEGQGGRVALVMIGFSEVDLARDGLKTALG
HHHHHHHCCCCCHHHEEEEEEHHHHHHHHEEECCCCEEEEEEEECCHHHHHHHHHHHHCC
TDPVVFCPGGHDVHGNAARLDLSGLEAALPELGASVSGFAVCAYFATRNPAHEIAARELI
CCCEEECCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCHHHHEEHHHCCCHHHHHHHHHHH
RDRTGLPVTASHELSAKLGGPRRALTTLLNARLISMIDRLVAATEGFLQARNIAAPLMVV
HHCCCCCEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
RGDGALVSAAFARQRPIETILSGPAASLVGARHMTGLENAVVSDIGGTTTDVAVLDQGRP
ECCCCCHHHHHHHCCCHHHHHCCCHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCCC
RLDPEGATVGGFRTMVEAVAMRTFGLGGDSEVALEDGALNPKILLGPRRLVPLALAGMAH
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEECCCHHHHHHHHHCCC
GEAVKSELERQLRSPNPGRMDGRFAVRTGVPDRLAAGLTAPEARLYEAIGATPLTLDRLL
HHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHCCCCCHHHHHHHHCCCCHHHHHHH
TSNAQNATLNRLVSRGLVHICGFTPSDAAHVLGKQANWDAATARLGAELFARKRDGRGQP
HCCCCHHHHHHHHHCCCEEEECCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCC
IAASPEVISERVLVTLTRWSAEYILETAFAEDGLDGAATVAHALVQRAVDAHPGIARLSV
CCCCHHHHHCCEEEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEE
ALDRPVIGLGASAPLHYAGLAPLVGNGCVVPEDTDVANALGAVVGQVRVSAEARVSQPRE
ECCCCEEECCCCCCCHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCHH
GLFRLASGGTVRDFLDEAAAIAAAEADVRAIVAERARDAGTDSAEIDVATEFKVSTVEAQ
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEHHHHH
RMFIEAHVVAVASGRPRIAV
HHEEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]