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The map label for this gene is dapB1

Identifier: 13473896

GI number: 13473896

Start: 3681010

End: 3681831

Strand: Direct

Name: dapB1

Synonym: mlr4642

Alternate gene names: 13473896

Gene position: 3681010-3681831 (Clockwise)

Preceding gene: 13473895

Following gene: 13473897

Centisome position: 52.32

GC content: 67.27

Gene sequence:

>822_bases
ATGAGCGAAGCAGGCGATATGGGCCTTGTGGTGGTGGGGGCAGCCGGCCGCATGGGCCAGACGCTGATCCGCGCCATCCA
CACCATTCCGGGCGCCCGTGTCATCGGCGCGGTCGAACGCGCGGATTCGCCGCATCTGGGCAAGGATGCCGGCGAGCTCG
CAGGCATCGGCATCATCAATGTGCCGATCGGTGACGATCCGCTGCCGGTCTTCGCCAAGGCCGACGGCGTGCTCGACTTC
ACCACGCCGGCCTCGTCGGTCGAATTCGCCGGCTACGCGGCGCAGGCCCGCATCGTCCATGTCATCGGCACGACCGGCTG
TTCGGCCGACGACAATGCCAGGATCGCCGCGGCGGCGCGCCACGCCACCATCGTCAAATCAGGCAATATGAGCCTCGGCG
TCAATCTGCTTGCGGTGCTGGTCGAACAGGCGGCGCGCGCGCTCGACGCCGATGATTTCGACATCGAGATTTTGGAAATG
CACCACAAGCACAAGGTCGACGCGCCGTCGGGCACGGCATTGTTGCTGGGTGAAGCCGCCGCCGCCGGGCGCGGCATTGC
GCTCGCCGGCAATGACGTGCGTTCACGCGACGGCCATACCGGTGTGCGAAAAACCGGGTCGATCGGCTTCGCCACGCTGC
GCGGCGGCTCGGTCGTCGGCGACCACAGCGTCATCCTTGCCGGCACTGGCGAGCGCATCACGCTGTCCCATCATGCCGAG
GACCGCGCCATCTTCGCCCGCGGCGCTGTCAAGGCGGCTCTGTGGGCCCGTGGCAAGAAGCCAGGACTCTATTCGATGCG
GGACGTGCTCGGCCTGAGCTGA

Upstream 100 bases:

>100_bases
GGGTGCAGGGCAAGAAGGGGCTGGGGCTTGTCGACGACAGCAAGCCGATCCAAACTCCGGTCCGGGCCACGCGTGCGAAA
AAGACGGCGGTGAGGAGCAC

Downstream 100 bases:

>100_bases
AACGGCCAATCTGCCCATTTTGCCAATCTGAAGGGAGCAAACATGTCGAGAACCCTTGTGCTCGTGCGCCATGGCCAGAG
CGAATGGAATTTGAAAAACC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR 1

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MSEAGDMGLVVVGAAGRMGQTLIRAIHTIPGARVIGAVERADSPHLGKDAGELAGIGIINVPIGDDPLPVFAKADGVLDF
TTPASSVEFAGYAAQARIVHVIGTTGCSADDNARIAAAARHATIVKSGNMSLGVNLLAVLVEQAARALDADDFDIEILEM
HHKHKVDAPSGTALLLGEAAAAGRGIALAGNDVRSRDGHTGVRKTGSIGFATLRGGSVVGDHSVILAGTGERITLSHHAE
DRAIFARGAVKAALWARGKKPGLYSMRDVLGLS

Sequences:

>Translated_273_residues
MSEAGDMGLVVVGAAGRMGQTLIRAIHTIPGARVIGAVERADSPHLGKDAGELAGIGIINVPIGDDPLPVFAKADGVLDF
TTPASSVEFAGYAAQARIVHVIGTTGCSADDNARIAAAARHATIVKSGNMSLGVNLLAVLVEQAARALDADDFDIEILEM
HHKHKVDAPSGTALLLGEAAAAGRGIALAGNDVRSRDGHTGVRKTGSIGFATLRGGSVVGDHSVILAGTGERITLSHHAE
DRAIFARGAVKAALWARGKKPGLYSMRDVLGLS
>Mature_272_residues
SEAGDMGLVVVGAAGRMGQTLIRAIHTIPGARVIGAVERADSPHLGKDAGELAGIGIINVPIGDDPLPVFAKADGVLDFT
TPASSVEFAGYAAQARIVHVIGTTGCSADDNARIAAAARHATIVKSGNMSLGVNLLAVLVEQAARALDADDFDIEILEMH
HKHKVDAPSGTALLLGEAAAAGRGIALAGNDVRSRDGHTGVRKTGSIGFATLRGGSVVGDHSVILAGTGERITLSHHAED
RAIFARGAVKAALWARGKKPGLYSMRDVLGLS

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=265, Percent_Identity=45.2830188679245, Blast_Score=199, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB1_RHILO (P58210)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_105464.1
- ProteinModelPortal:   P58210
- SMR:   P58210
- GeneID:   1228125
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr4642
- NMPDR:   fig|266835.1.peg.3568
- HOGENOM:   HBG594002
- OMA:   TERPGHD
- ProtClustDB:   PRK00048
- BRENDA:   1.3.1.26
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 27893; Mature: 27762

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS01298 DAPB; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAGDMGLVVVGAAGRMGQTLIRAIHTIPGARVIGAVERADSPHLGKDAGELAGIGIIN
CCCCCCCCEEEEECCCCHHHHHHHHHHHCCCHHEEHHHHHCCCCCCCCCCHHHCCCEEEE
VPIGDDPLPVFAKADGVLDFTTPASSVEFAGYAAQARIVHVIGTTGCSADDNARIAAAAR
CCCCCCCCCEEEECCCEEEECCCCCCEEECCEEECEEEEEEEECCCCCCCCCCEEEEEEH
HATIVKSGNMSLGVNLLAVLVEQAARALDADDFDIEILEMHHKHKVDAPSGTALLLGEAA
EEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHCCCCCCCCCEEEEECCC
AAGRGIALAGNDVRSRDGHTGVRKTGSIGFATLRGGSVVGDHSVILAGTGERITLSHHAE
CCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEECCCEEECCCEEEEEECCCEEEEECCCC
DRAIFARGAVKAALWARGKKPGLYSMRDVLGLS
CCEEEHHHHHHHHHHHCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
SEAGDMGLVVVGAAGRMGQTLIRAIHTIPGARVIGAVERADSPHLGKDAGELAGIGIIN
CCCCCCCEEEEECCCCHHHHHHHHHHHCCCHHEEHHHHHCCCCCCCCCCHHHCCCEEEE
VPIGDDPLPVFAKADGVLDFTTPASSVEFAGYAAQARIVHVIGTTGCSADDNARIAAAAR
CCCCCCCCCEEEECCCEEEECCCCCCEEECCEEECEEEEEEEECCCCCCCCCCEEEEEEH
HATIVKSGNMSLGVNLLAVLVEQAARALDADDFDIEILEMHHKHKVDAPSGTALLLGEAA
EEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHCCCCCCCCCEEEEECCC
AAGRGIALAGNDVRSRDGHTGVRKTGSIGFATLRGGSVVGDHSVILAGTGERITLSHHAE
CCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEECCCEEECCCEEEEEECCCEEEEECCCC
DRAIFARGAVKAALWARGKKPGLYSMRDVLGLS
CCEEEHHHHHHHHHHHCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968