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The map label for this gene is rsmB [H]

Identifier: 13473485

GI number: 13473485

Start: 3277576

End: 3278964

Strand: Direct

Name: rsmB [H]

Synonym: mlr4098

Alternate gene names: 13473485

Gene position: 3277576-3278964 (Clockwise)

Preceding gene: 13473484

Following gene: 13473486

Centisome position: 46.58

GC content: 68.18

Gene sequence:

>1389_bases
ATGGTCGTGAGCGTGGCGGGACCTCGACGCGCAGGCTCAGGCGATCAGGACCATAGAGACGGCGGCGAATTCGTCGCCGG
TCTCGCCGCCCGCAAGGCGGCGGCGCGGCTGCTGGCCGCTGTCATCGACGCCAGGACACCGCTCGACGGACTGACCGACC
ATGAGAACGGCCACCCGCAATACAAGGCGCTCGATTTGCGCGACCGTGGCCTGGTGCGGGCCATTCTGGTCACCGCGCTG
CGCTTCCGCATGACCATCACCGGGCTGCTGGCGCGGCGCCTGGAAAAGCCGCTGCCGCCCAACGCCACCGCTTTGTCGCA
CATCTTGCATGTGGCGGCGGCACAGATCCTGTTCCTCGACATTCCCGACAGCGCCGCCGTCGACCTCGCGGTCACCCATG
CCAAGTCCGATCCGCGCACCCAACGTTTCTCCGGTCTGGTCAACGGCGTGCTGCGCACGCTGGCCCGGGCCAAGGAGACG
GAACTGCCCGCCGCCCTTGCCGCCACCGACGAAGCGCCAAAATGGTTCTCCGACCGGCTGAAAGCCGCCTATGGCGAGGA
CAAAGCGAAACAGATCCTCGCCGCGCACCGTTACGAGGCGCCCGTCGACTTCTCGGTTAGGGCCGATCCGGAACTCTGGG
CCGAAAAGCTCGGCGGTATCGTGCTGCCCACCGGCACGGTGCGCGTGGAAAACCTTGCCGGAGCCGTCACCGACCTGCCC
GGCTTCGCGGAAGGCGCCTGGTGGGTCCAGGATGCCGCCGCCAGCCTGCCGGCGCGGCTCTTTGGTGATGTCGGCGGATT
GCGTGTCGCCGACCTCTGCGCCGCGCCCGGCGGCAAGACCGCCCAGCTGATCCTGGCCGGCGCCAAGGTCACCGCTGTCG
ATACCTCGAAGAACCGGCTGGCGCGGCTGGCGCAGAATCTCGACCGCCTCGGCCTGTCGGCCGAGATCGTCCAGGCCGAC
CTGCTCAAATACGAGCCCGCGGAGCTGTTCGATGCGGTGCTGCTCGACGCGCCCTGCTCGTCGACAGGCACGGTGCGACG
GCATCCCGACGTGCCATGGACCAAGACGGCGGCCGATGTCGAAAAGCTCGCCGACCTGCAAAGGCGGTTGCTCGCCCGCG
CCGTCACGCTGGTCAGGCCCGGTGGCCGGATCGTCTTTTCCAACTGTTCGCTCGACCCGCTCGAAGGGGAAGAGCTTCAT
CTGGCGTTTCTGAAGGAAACGCCAGTGGTCGTCGACGATCCGCTGCGGCAAGGGGAGATCGCCGGCATCGACCCTTTCCT
GACGGCGCAAGGCACGCTGCGCACCACGCCCGCCGACCTTGATCTCGGTGCCCCGGAGCGCTCGGGCCTGGACGGCTTCT
TTGCCGCGCGCATGCGCCGCGCTCTTTAA

Upstream 100 bases:

>100_bases
CCGGCCCGTGGGGCCAGGCCCCTCAAGCAGAACAGCCGGCGGAGCCGGAAAGGCCGAAGGCCAACCCATGGGGACGCAAT
CCGACCGGGCCCAAAGGCCG

Downstream 100 bases:

>100_bases
AGCAGTCTTTCGCGACCGCGAAAACTGCTCGCCCCGCAGGTTTCGCCGCCACCAAAAGAGGACATAAGTCACGGCAGACG
CGACTTTTTTAGGGACGACC

Product: hypothetical protein

Products: NA

Alternate protein names: 16S rRNA m5C967 methyltransferase; rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MVVSVAGPRRAGSGDQDHRDGGEFVAGLAARKAAARLLAAVIDARTPLDGLTDHENGHPQYKALDLRDRGLVRAILVTAL
RFRMTITGLLARRLEKPLPPNATALSHILHVAAAQILFLDIPDSAAVDLAVTHAKSDPRTQRFSGLVNGVLRTLARAKET
ELPAALAATDEAPKWFSDRLKAAYGEDKAKQILAAHRYEAPVDFSVRADPELWAEKLGGIVLPTGTVRVENLAGAVTDLP
GFAEGAWWVQDAAASLPARLFGDVGGLRVADLCAAPGGKTAQLILAGAKVTAVDTSKNRLARLAQNLDRLGLSAEIVQAD
LLKYEPAELFDAVLLDAPCSSTGTVRRHPDVPWTKTAADVEKLADLQRRLLARAVTLVRPGGRIVFSNCSLDPLEGEELH
LAFLKETPVVVDDPLRQGEIAGIDPFLTAQGTLRTTPADLDLGAPERSGLDGFFAARMRRAL

Sequences:

>Translated_462_residues
MVVSVAGPRRAGSGDQDHRDGGEFVAGLAARKAAARLLAAVIDARTPLDGLTDHENGHPQYKALDLRDRGLVRAILVTAL
RFRMTITGLLARRLEKPLPPNATALSHILHVAAAQILFLDIPDSAAVDLAVTHAKSDPRTQRFSGLVNGVLRTLARAKET
ELPAALAATDEAPKWFSDRLKAAYGEDKAKQILAAHRYEAPVDFSVRADPELWAEKLGGIVLPTGTVRVENLAGAVTDLP
GFAEGAWWVQDAAASLPARLFGDVGGLRVADLCAAPGGKTAQLILAGAKVTAVDTSKNRLARLAQNLDRLGLSAEIVQAD
LLKYEPAELFDAVLLDAPCSSTGTVRRHPDVPWTKTAADVEKLADLQRRLLARAVTLVRPGGRIVFSNCSLDPLEGEELH
LAFLKETPVVVDDPLRQGEIAGIDPFLTAQGTLRTTPADLDLGAPERSGLDGFFAARMRRAL
>Mature_462_residues
MVVSVAGPRRAGSGDQDHRDGGEFVAGLAARKAAARLLAAVIDARTPLDGLTDHENGHPQYKALDLRDRGLVRAILVTAL
RFRMTITGLLARRLEKPLPPNATALSHILHVAAAQILFLDIPDSAAVDLAVTHAKSDPRTQRFSGLVNGVLRTLARAKET
ELPAALAATDEAPKWFSDRLKAAYGEDKAKQILAAHRYEAPVDFSVRADPELWAEKLGGIVLPTGTVRVENLAGAVTDLP
GFAEGAWWVQDAAASLPARLFGDVGGLRVADLCAAPGGKTAQLILAGAKVTAVDTSKNRLARLAQNLDRLGLSAEIVQAD
LLKYEPAELFDAVLLDAPCSSTGTVRRHPDVPWTKTAADVEKLADLQRRLLARAVTLVRPGGRIVFSNCSLDPLEGEELH
LAFLKETPVVVDDPLRQGEIAGIDPFLTAQGTLRTTPADLDLGAPERSGLDGFFAARMRRAL

Specific function: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=252, Percent_Identity=28.968253968254, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI76150623, Length=252, Percent_Identity=28.968253968254, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI32698918, Length=169, Percent_Identity=33.7278106508876, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI270288816, Length=242, Percent_Identity=33.0578512396694, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI23199998, Length=242, Percent_Identity=33.0578512396694, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI270288818, Length=242, Percent_Identity=33.0578512396694, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI8922322, Length=242, Percent_Identity=33.0578512396694, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI39995082, Length=180, Percent_Identity=31.1111111111111, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI301336155, Length=180, Percent_Identity=31.1111111111111, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI40316918, Length=164, Percent_Identity=34.7560975609756, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI2367212, Length=446, Percent_Identity=30.9417040358744, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI87081985, Length=258, Percent_Identity=33.7209302325581, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17536757, Length=235, Percent_Identity=30.2127659574468, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115534021, Length=257, Percent_Identity=28.7937743190661, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71998419, Length=256, Percent_Identity=28.90625, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324268, Length=237, Percent_Identity=31.6455696202532, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6319447, Length=177, Percent_Identity=32.7683615819209, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI22024126, Length=233, Percent_Identity=32.618025751073, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21355201, Length=172, Percent_Identity=34.8837209302326, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI19920494, Length=225, Percent_Identity=27.5555555555556, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24668781, Length=171, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21356513, Length=174, Percent_Identity=33.9080459770115, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: =2.1.1.176 [H]

Molecular weight: Translated: 49333; Mature: 49333

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVSVAGPRRAGSGDQDHRDGGEFVAGLAARKAAARLLAAVIDARTPLDGLTDHENGHPQ
CEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
YKALDLRDRGLVRAILVTALRFRMTITGLLARRLEKPLPPNATALSHILHVAAAQILFLD
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEE
IPDSAAVDLAVTHAKSDPRTQRFSGLVNGVLRTLARAKETELPAALAATDEAPKWFSDRL
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHH
KAAYGEDKAKQILAAHRYEAPVDFSVRADPELWAEKLGGIVLPTGTVRVENLAGAVTDLP
HHHHCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCEEECCCCEEEHHHHHHHHCCC
GFAEGAWWVQDAAASLPARLFGDVGGLRVADLCAAPGGKTAQLILAGAKVTAVDTSKNRL
CCCCCHHHHHHHHHHCCHHHHHCCCCCHHHHHHCCCCCCCEEEEEECCEEEEEECCHHHH
ARLAQNLDRLGLSAEIVQADLLKYEPAELFDAVLLDAPCSSTGTVRRHPDVPWTKTAADV
HHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHH
EKLADLQRRLLARAVTLVRPGGRIVFSNCSLDPLEGEELHLAFLKETPVVVDDPLRQGEI
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEEECCCCEEECCCCCCCCC
AGIDPFLTAQGTLRTTPADLDLGAPERSGLDGFFAARMRRAL
CCCCCCCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MVVSVAGPRRAGSGDQDHRDGGEFVAGLAARKAAARLLAAVIDARTPLDGLTDHENGHPQ
CEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
YKALDLRDRGLVRAILVTALRFRMTITGLLARRLEKPLPPNATALSHILHVAAAQILFLD
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEE
IPDSAAVDLAVTHAKSDPRTQRFSGLVNGVLRTLARAKETELPAALAATDEAPKWFSDRL
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHH
KAAYGEDKAKQILAAHRYEAPVDFSVRADPELWAEKLGGIVLPTGTVRVENLAGAVTDLP
HHHHCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCEEECCCCEEEHHHHHHHHCCC
GFAEGAWWVQDAAASLPARLFGDVGGLRVADLCAAPGGKTAQLILAGAKVTAVDTSKNRL
CCCCCHHHHHHHHHHCCHHHHHCCCCCHHHHHHCCCCCCCEEEEEECCEEEEEECCHHHH
ARLAQNLDRLGLSAEIVQADLLKYEPAELFDAVLLDAPCSSTGTVRRHPDVPWTKTAADV
HHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHH
EKLADLQRRLLARAVTLVRPGGRIVFSNCSLDPLEGEELHLAFLKETPVVVDDPLRQGEI
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEEECCCCEEECCCCCCCCC
AGIDPFLTAQGTLRTTPADLDLGAPERSGLDGFFAARMRRAL
CCCCCCCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA