Click here to switch to the map view.

The map label for this gene is atpA [H]

Identifier: 13473458

GI number: 13473458

Start: 3248017

End: 3249546

Strand: Reverse

Name: atpA [H]

Synonym: mll4065

Alternate gene names: 13473458

Gene position: 3249546-3248017 (Counterclockwise)

Preceding gene: 13473459

Following gene: 13473457

Centisome position: 46.18

GC content: 64.51

Gene sequence:

>1530_bases
ATGGACATCCGCGCCGCGGAAATTTCCGCAATTCTGAAAGACCAGATCAAGAATTTCGGCAGGGAGGCCGAGGTCTCCGA
AGTTGGACAGGTGCTGTCCGTCGGTGACGGTATCGCCCGCGTCTACGGCCTCGACAATGTCCAGGCCGGCGAGATGGTCG
AATTCCCCGGCGGCATCCGCGGCATGGCGCTCAACCTCGAAGCCGACAATGTCGGCGTCGTCATCTTCGGCGCCGACCGC
GACATCAAGGAAGGCGACACCGTCAAGCGCACCGGCGCCATCGTCGACGTTCCGGTCGGTCCGGGCCTGCTCGGCCGCGT
CGTCGACGCGCTCGGCAACCCGATCGACGGCAAGGGCCCGATCAAGGCGACCGAACGCAAGCGCGTCGACGTCAAGGCGC
CCGGTATCATCCCGCGCAAGTCGGTGCATGAGCCGATGTCGACCGGCCTCAAGGCCATCGATGCGCTGATCCCGGTCGGC
CGTGGCCAGCGCGAGCTGGTCATCGGCGACCGTCAGACCGGCAAGACCGCCATCATCCTCGACACGATGCTCAACCAGAA
GTCGGTGCACGACAACGGCCCCGAGAAGGAAAAGCTCTACTGCGTCTATGTCGCCGTCGGCCAGAAGCGCTCGACCGTCG
CGCAGTTCGTCAAGGTGCTGGAAGAGCGCGGCGCGCTCGAATATTCGATCATTGTCGCCGCCACCGCTTCCGATCCGGCG
CCGATGCAGTTCCTGGCGCCGTTCGCCGGCTGCACCATGGGCGAGTATTTCCGCGACAATGGCATGCATGCGCTGATCAG
CTACGACGATCTGTCGAAGCAGGCCGTCGCCTATCGCCAGATGTCGCTGCTCCTGCGCCGCCCGCCGGGCCGCGAAGCCT
ATCCGGGCGACGTCTTCTATCTGCACTCGCGCCTGCTCGAGCGCGCCGCCAAGCTCAATGACGATCTGGGCAATGGCTCG
CTGACGGCGCTGCCAGTCATCGAAACGCAGGCCAACGACGTGTCGGCCTACATCCCGACCAACGTGATCTCGATCACCGA
CGGCCAGATATTCCTCGAAACCAACCTGTTCTTCCAGGGCATCCGTCCGGCCGTCAACGTCGGTCTGTCGGTGTCGCGCG
TCGGTTCCTCGGCGCAGATCAAGGCGATGAAGCAGGTTGCCGGCTCGATCAAGGGCGAGCTCGCGCAGTACCGCGAAATG
GCGGCCTTCGCGCAGTTCGGCTCGGATCTCGACGCCGCCACGCAGCGCCTGCTCAACCGCGGATCGCGCCTGACCGAACT
CCTGAAGCAGCCGCAGTTCTCGCCGCTGAAGACGGAAGAGCAGGTCGCGGTGATCTTCGCCGGCGTCAACGGCTATCTCG
ACAAGCTGCCGGTCAACCAGGTCGGCAAGTTCGAGCATGGCCTGCTCAGCCATATGCGTGCGGCCGGCAAGGACGTTCTC
GACGCCATCCGCAAGGAAAAGGCGCTGTCGGACGATCTGCGCGCCAAGCTGAAGGCAGAGATCGACGCTTTCGCCAAGAC
CTTCGCCTGA

Upstream 100 bases:

>100_bases
TGCTCGGCGGGCTGGTGGTCAAGATAGGCTCGCGCCAGATCGATACGTCGCTCAAAACCAAACTCAATTCGCTCAAGCTT
GCACTGAAAGAGGTCGGCTG

Downstream 100 bases:

>100_bases
GCGAAGCGACAAGACGGGATCAGGTTTGAAGCATGCCTTCATTAAAAGACCTTCGTAACCGTATCGCCTCGGTCAAGGCG
ACGCAGAAGATCACCAAGGC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MDIRAAEISAILKDQIKNFGREAEVSEVGQVLSVGDGIARVYGLDNVQAGEMVEFPGGIRGMALNLEADNVGVVIFGADR
DIKEGDTVKRTGAIVDVPVGPGLLGRVVDALGNPIDGKGPIKATERKRVDVKAPGIIPRKSVHEPMSTGLKAIDALIPVG
RGQRELVIGDRQTGKTAIILDTMLNQKSVHDNGPEKEKLYCVYVAVGQKRSTVAQFVKVLEERGALEYSIIVAATASDPA
PMQFLAPFAGCTMGEYFRDNGMHALISYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDDLGNGS
LTALPVIETQANDVSAYIPTNVISITDGQIFLETNLFFQGIRPAVNVGLSVSRVGSSAQIKAMKQVAGSIKGELAQYREM
AAFAQFGSDLDAATQRLLNRGSRLTELLKQPQFSPLKTEEQVAVIFAGVNGYLDKLPVNQVGKFEHGLLSHMRAAGKDVL
DAIRKEKALSDDLRAKLKAEIDAFAKTFA

Sequences:

>Translated_509_residues
MDIRAAEISAILKDQIKNFGREAEVSEVGQVLSVGDGIARVYGLDNVQAGEMVEFPGGIRGMALNLEADNVGVVIFGADR
DIKEGDTVKRTGAIVDVPVGPGLLGRVVDALGNPIDGKGPIKATERKRVDVKAPGIIPRKSVHEPMSTGLKAIDALIPVG
RGQRELVIGDRQTGKTAIILDTMLNQKSVHDNGPEKEKLYCVYVAVGQKRSTVAQFVKVLEERGALEYSIIVAATASDPA
PMQFLAPFAGCTMGEYFRDNGMHALISYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDDLGNGS
LTALPVIETQANDVSAYIPTNVISITDGQIFLETNLFFQGIRPAVNVGLSVSRVGSSAQIKAMKQVAGSIKGELAQYREM
AAFAQFGSDLDAATQRLLNRGSRLTELLKQPQFSPLKTEEQVAVIFAGVNGYLDKLPVNQVGKFEHGLLSHMRAAGKDVL
DAIRKEKALSDDLRAKLKAEIDAFAKTFA
>Mature_509_residues
MDIRAAEISAILKDQIKNFGREAEVSEVGQVLSVGDGIARVYGLDNVQAGEMVEFPGGIRGMALNLEADNVGVVIFGADR
DIKEGDTVKRTGAIVDVPVGPGLLGRVVDALGNPIDGKGPIKATERKRVDVKAPGIIPRKSVHEPMSTGLKAIDALIPVG
RGQRELVIGDRQTGKTAIILDTMLNQKSVHDNGPEKEKLYCVYVAVGQKRSTVAQFVKVLEERGALEYSIIVAATASDPA
PMQFLAPFAGCTMGEYFRDNGMHALISYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDDLGNGS
LTALPVIETQANDVSAYIPTNVISITDGQIFLETNLFFQGIRPAVNVGLSVSRVGSSAQIKAMKQVAGSIKGELAQYREM
AAFAQFGSDLDAATQRLLNRGSRLTELLKQPQFSPLKTEEQVAVIFAGVNGYLDKLPVNQVGKFEHGLLSHMRAAGKDVL
DAIRKEKALSDDLRAKLKAEIDAFAKTFA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=503, Percent_Identity=70.9741550695825, Blast_Score=734, Evalue=0.0,
Organism=Homo sapiens, GI4757810, Length=503, Percent_Identity=70.9741550695825, Blast_Score=734, Evalue=0.0,
Organism=Homo sapiens, GI19913428, Length=350, Percent_Identity=28, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI19913426, Length=355, Percent_Identity=27.887323943662, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI32189394, Length=405, Percent_Identity=25.4320987654321, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI19913424, Length=249, Percent_Identity=27.3092369477912, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1790172, Length=518, Percent_Identity=54.6332046332046, Blast_Score=567, Evalue=1e-163,
Organism=Escherichia coli, GI1790170, Length=426, Percent_Identity=25.3521126760563, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788251, Length=345, Percent_Identity=27.8260869565217, Blast_Score=110, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71988063, Length=503, Percent_Identity=71.1729622266402, Blast_Score=738, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988080, Length=503, Percent_Identity=71.1729622266402, Blast_Score=736, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988074, Length=503, Percent_Identity=65.4075546719682, Blast_Score=666, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17570191, Length=334, Percent_Identity=27.2455089820359, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17510931, Length=297, Percent_Identity=29.2929292929293, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=377, Percent_Identity=25.1989389920424, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71988068, Length=76, Percent_Identity=57.8947368421053, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=64, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319370, Length=502, Percent_Identity=69.5219123505976, Blast_Score=732, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=373, Percent_Identity=30.0268096514745, Blast_Score=133, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6322581, Length=404, Percent_Identity=25.990099009901, Blast_Score=114, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24658560, Length=505, Percent_Identity=70.4950495049505, Blast_Score=729, Evalue=0.0,
Organism=Drosophila melanogaster, GI281361666, Length=334, Percent_Identity=29.0419161676647, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24646341, Length=334, Percent_Identity=29.0419161676647, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17136796, Length=334, Percent_Identity=29.0419161676647, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24638766, Length=412, Percent_Identity=25.2427184466019, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28574560, Length=401, Percent_Identity=25.6857855361596, Blast_Score=99, Evalue=8e-21,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 54957; Mature: 54957

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIRAAEISAILKDQIKNFGREAEVSEVGQVLSVGDGIARVYGLDNVQAGEMVEFPGGIR
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCEEECCCCCC
GMALNLEADNVGVVIFGADRDIKEGDTVKRTGAIVDVPVGPGLLGRVVDALGNPIDGKGP
EEEEEEECCCEEEEEECCCCCCCCCCCEECCCCEEEECCCCCHHHHHHHHHCCCCCCCCC
IKATERKRVDVKAPGIIPRKSVHEPMSTGLKAIDALIPVGRGQRELVIGDRQTGKTAIIL
CCCCCCCEEEECCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEE
DTMLNQKSVHDNGPEKEKLYCVYVAVGQKRSTVAQFVKVLEERGALEYSIIVAATASDPA
EHHHCCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCC
PMQFLAPFAGCTMGEYFRDNGMHALISYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFY
CHHHHHHHHCCCHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LHSRLLERAAKLNDDLGNGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETNLFFQG
HHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECHHHHC
IRPAVNVGLSVSRVGSSAQIKAMKQVAGSIKGELAQYREMAAFAQFGSDLDAATQRLLNR
CCHHHHCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
GSRLTELLKQPQFSPLKTEEQVAVIFAGVNGYLDKLPVNQVGKFEHGLLSHMRAAGKDVL
CHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHCCCHHHHCCHHHHHHHHHHHCCHHHH
DAIRKEKALSDDLRAKLKAEIDAFAKTFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDIRAAEISAILKDQIKNFGREAEVSEVGQVLSVGDGIARVYGLDNVQAGEMVEFPGGIR
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCEEECCCCCC
GMALNLEADNVGVVIFGADRDIKEGDTVKRTGAIVDVPVGPGLLGRVVDALGNPIDGKGP
EEEEEEECCCEEEEEECCCCCCCCCCCEECCCCEEEECCCCCHHHHHHHHHCCCCCCCCC
IKATERKRVDVKAPGIIPRKSVHEPMSTGLKAIDALIPVGRGQRELVIGDRQTGKTAIIL
CCCCCCCEEEECCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEE
DTMLNQKSVHDNGPEKEKLYCVYVAVGQKRSTVAQFVKVLEERGALEYSIIVAATASDPA
EHHHCCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCC
PMQFLAPFAGCTMGEYFRDNGMHALISYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFY
CHHHHHHHHCCCHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LHSRLLERAAKLNDDLGNGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETNLFFQG
HHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECHHHHC
IRPAVNVGLSVSRVGSSAQIKAMKQVAGSIKGELAQYREMAAFAQFGSDLDAATQRLLNR
CCHHHHCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
GSRLTELLKQPQFSPLKTEEQVAVIFAGVNGYLDKLPVNQVGKFEHGLLSHMRAAGKDVL
CHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHCCCHHHHCCHHHHHHHHHHHCCHHHH
DAIRKEKALSDDLRAKLKAEIDAFAKTFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA