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The map label for this gene is atpH

Identifier: 13473459

GI number: 13473459

Start: 3249546

End: 3250106

Strand: Reverse

Name: atpH

Synonym: mll4066

Alternate gene names: 13473459

Gene position: 3250106-3249546 (Counterclockwise)

Preceding gene: 13473460

Following gene: 13473458

Centisome position: 46.19

GC content: 63.28

Gene sequence:

>561_bases
GTGGCCCAATCGTCATCGCCAATCTCAGGTGTCGCAGAACGCTACGCGGGTTCGCTGTTCGAACTCGCCCTGCAGGCAAA
TTCCGTGGCCAAGGTCGAGTCCGACCTCAACAGTTTCGAGGCGATGCTGGCTGGCAGTTCCGACCTGACCCGGCTGATCA
ACAGCCCGGTGTTCTCCGGCGAGGAGCAGGCCAAGGCCATCGCGGCGATCGCCGACAAGGCTGGGATCACCGGCCTCACC
GGTAATTTCCTGCGCGTCGTCGCCCGCAATCGCCGGCTGTTCGCCGTGCCCGGCATGATCAAGGCGTTCCGCCAGATCGC
CGCCGAACACCGTGGCGAGACCGCTGCTGAAGTGACGTCGGCTCACGAGCTGACGGCTGCCCAGCAGACCGAACTCAAGG
CGGCGCTGAAAAGCGTTGCCGGCAAGGACGTGGCCATCTCCGTCACCGTCGATCCGTCGCTGCTCGGCGGGCTGGTGGTC
AAGATAGGCTCGCGCCAGATCGATACGTCGCTCAAAACCAAACTCAATTCGCTCAAGCTTGCACTGAAAGAGGTCGGCTG
A

Upstream 100 bases:

>100_bases
GCCTCCGTGCTTGAAAAAATGCAGTAAGGTCAAAGATTTAGCCAGAGTTTTTGCTCGCGCCAACAATCTGCGGCCTGTCA
GACAAGAGAAAAGACGGTCC

Downstream 100 bases:

>100_bases
TGGACATCCGCGCCGCGGAAATTTCCGCAATTCTGAAAGACCAGATCAAGAATTTCGGCAGGGAGGCCGAGGTCTCCGAA
GTTGGACAGGTGCTGTCCGT

Product: F0F1 ATP synthase subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MAQSSSPISGVAERYAGSLFELALQANSVAKVESDLNSFEAMLAGSSDLTRLINSPVFSGEEQAKAIAAIADKAGITGLT
GNFLRVVARNRRLFAVPGMIKAFRQIAAEHRGETAAEVTSAHELTAAQQTELKAALKSVAGKDVAISVTVDPSLLGGLVV
KIGSRQIDTSLKTKLNSLKLALKEVG

Sequences:

>Translated_186_residues
MAQSSSPISGVAERYAGSLFELALQANSVAKVESDLNSFEAMLAGSSDLTRLINSPVFSGEEQAKAIAAIADKAGITGLT
GNFLRVVARNRRLFAVPGMIKAFRQIAAEHRGETAAEVTSAHELTAAQQTELKAALKSVAGKDVAISVTVDPSLLGGLVV
KIGSRQIDTSLKTKLNSLKLALKEVG
>Mature_185_residues
AQSSSPISGVAERYAGSLFELALQANSVAKVESDLNSFEAMLAGSSDLTRLINSPVFSGEEQAKAIAAIADKAGITGLTG
NFLRVVARNRRLFAVPGMIKAFRQIAAEHRGETAAEVTSAHELTAAQQTELKAALKSVAGKDVAISVTVDPSLLGGLVVK
IGSRQIDTSLKTKLNSLKLALKEVG

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

Organism=Homo sapiens, GI4502303, Length=180, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=2e-21,
Organism=Escherichia coli, GI1790173, Length=172, Percent_Identity=26.7441860465116, Blast_Score=61, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71984710, Length=177, Percent_Identity=33.8983050847458, Blast_Score=113, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI71984717, Length=177, Percent_Identity=33.8983050847458, Blast_Score=113, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6320504, Length=180, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24647054, Length=170, Percent_Identity=34.1176470588235, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24647056, Length=98, Percent_Identity=41.8367346938776, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_RHILO (Q98EV5)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_105026.1
- ProteinModelPortal:   Q98EV5
- SMR:   Q98EV5
- GeneID:   1227687
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll4066
- NMPDR:   fig|266835.1.peg.3130
- HOGENOM:   HBG668108
- OMA:   FIAICGE
- ProtClustDB:   PRK05758
- HAMAP:   MF_01416
- InterPro:   IPR000711
- InterPro:   IPR020781
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 19406; Mature: 19275

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQSSSPISGVAERYAGSLFELALQANSVAKVESDLNSFEAMLAGSSDLTRLINSPVFSG
CCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCC
EEQAKAIAAIADKAGITGLTGNFLRVVARNRRLFAVPGMIKAFRQIAAEHRGETAAEVTS
HHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHH
AHELTAAQQTELKAALKSVAGKDVAISVTVDPSLLGGLVVKIGSRQIDTSLKTKLNSLKL
HHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ALKEVG
HHHHCC
>Mature Secondary Structure 
AQSSSPISGVAERYAGSLFELALQANSVAKVESDLNSFEAMLAGSSDLTRLINSPVFSG
CCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCC
EEQAKAIAAIADKAGITGLTGNFLRVVARNRRLFAVPGMIKAFRQIAAEHRGETAAEVTS
HHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHH
AHELTAAQQTELKAALKSVAGKDVAISVTVDPSLLGGLVVKIGSRQIDTSLKTKLNSLKL
HHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ALKEVG
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11214968