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The map label for this gene is cls [C]

Identifier: 13473405

GI number: 13473405

Start: 3192026

End: 3193090

Strand: Direct

Name: cls [C]

Synonym: mlr3991

Alternate gene names: 13473405

Gene position: 3192026-3193090 (Clockwise)

Preceding gene: 13473404

Following gene: 13473416

Centisome position: 45.37

GC content: 60.38

Gene sequence:

>1065_bases
TTGATCCGCCATCATGCCGCCCTTGGCACCAAGGTGCGCATTCTGGTCACCGACGTGCTGGAGCGCGAAAAGGACGACGC
CATGCTGCACCGGCTGGCGGCGGAGTTCCCCAATGTCGAATTGCAGGAATATCGCTGGCGCGCCGATCATGGCGCGCCGA
TCGACGAGCAGATTTCACAGCTGCACAAGACCCATCATATCAAGATGCTGGCGACGCTGGCTGTGGACCCAGCGCGCTCG
CGCGTCATCATCGGCGGCCGCAACATCCATGACGGCTTCCTGTTCCACAGTCCGATCGACCTGTCGCGCTATCCGGACCT
GCAGCAATACGGCAAGACCGACGGCTTTTCGCTGAACTACTATTCGAACTGGAGCGACTTCGACATCGAGTTCGCCGACC
GGGCGACGGTCGAGACGCTCGCCGCGCATCTGTCGACAATATGGTTGCGCGATGCCGACACCAATCTGGCGCGCCCCTTC
TCCATCCCGGTGCGTGGAGATGGCCGCCCCCGCGGCAATGCCCGGCATTTCATTTCCGTGCCCTATGAGGACGACCATGC
GCTGGAGGGCTATTTTGTCGAACTGGTTGACGCCGCCCGGCGCCATATCCAGATCGTCAACCCCTACCTCAATCTGACGC
CGAGCCTCGCCCAGGCCTTTGACCGGGCGCTCGCCCGCGGCGTAAAGATCGACATTGTCGGCCGCATCGACCTCAAGGGC
GATATTGGCGGCAAGTTCCTCACCGCGCTCAACAGGCTGTTCGTCGAGAAATATGGCGACCGCATCAACATCCGCGAGTT
CAAGGCGCCCGACGTGGTGCTGCATTCCAAGATCATGATGATCGACGAAAGGCTGGTCGCCATCTCCTCGGTCAACCTCA
ACAACCGCAGCTTCTTCCACGATTCAGAGAACGGCATGATGGTGCTCGATCCCGCCTTCTACGTCAGGATGAAGCCGATC
TATGACGACTATCTCGCCCATTCGAATCCGGTTTCCGCCAACGTGACGATCCCATGGGCCTATCGGCTGCTGTTCGATGA
AGCCTGGGTCAGGCAGGCATTCTGA

Upstream 100 bases:

>100_bases
GGAGCTGCCTCTCGATTTCTCCAAGGCGCCACGGCTGAAGCTGATCTATCTGTCCTCGCTGGAATTCAAGGCGGACTTTT
CCGGCTGCATCATCGAGCGG

Downstream 100 bases:

>100_bases
TCTCCCCGCGCCGCGCCTATTTCAGGTAGCGCTCCTGTGCCAGGGCACGGGCATCGATCTCGGGCACCTTGTTCGACATG
ATGTCGGCCAGCACCTTGGC

Product: hypothetical protein

Products: Biphosphatidylglycerol; Glycerol. [C]

Alternate protein names: None

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MIRHHAALGTKVRILVTDVLEREKDDAMLHRLAAEFPNVELQEYRWRADHGAPIDEQISQLHKTHHIKMLATLAVDPARS
RVIIGGRNIHDGFLFHSPIDLSRYPDLQQYGKTDGFSLNYYSNWSDFDIEFADRATVETLAAHLSTIWLRDADTNLARPF
SIPVRGDGRPRGNARHFISVPYEDDHALEGYFVELVDAARRHIQIVNPYLNLTPSLAQAFDRALARGVKIDIVGRIDLKG
DIGGKFLTALNRLFVEKYGDRINIREFKAPDVVLHSKIMMIDERLVAISSVNLNNRSFFHDSENGMMVLDPAFYVRMKPI
YDDYLAHSNPVSANVTIPWAYRLLFDEAWVRQAF

Sequences:

>Translated_354_residues
MIRHHAALGTKVRILVTDVLEREKDDAMLHRLAAEFPNVELQEYRWRADHGAPIDEQISQLHKTHHIKMLATLAVDPARS
RVIIGGRNIHDGFLFHSPIDLSRYPDLQQYGKTDGFSLNYYSNWSDFDIEFADRATVETLAAHLSTIWLRDADTNLARPF
SIPVRGDGRPRGNARHFISVPYEDDHALEGYFVELVDAARRHIQIVNPYLNLTPSLAQAFDRALARGVKIDIVGRIDLKG
DIGGKFLTALNRLFVEKYGDRINIREFKAPDVVLHSKIMMIDERLVAISSVNLNNRSFFHDSENGMMVLDPAFYVRMKPI
YDDYLAHSNPVSANVTIPWAYRLLFDEAWVRQAF
>Mature_354_residues
MIRHHAALGTKVRILVTDVLEREKDDAMLHRLAAEFPNVELQEYRWRADHGAPIDEQISQLHKTHHIKMLATLAVDPARS
RVIIGGRNIHDGFLFHSPIDLSRYPDLQQYGKTDGFSLNYYSNWSDFDIEFADRATVETLAAHLSTIWLRDADTNLARPF
SIPVRGDGRPRGNARHFISVPYEDDHALEGYFVELVDAARRHIQIVNPYLNLTPSLAQAFDRALARGVKIDIVGRIDLKG
DIGGKFLTALNRLFVEKYGDRINIREFKAPDVVLHSKIMMIDERLVAISSVNLNNRSFFHDSENGMMVLDPAFYVRMKPI
YDDYLAHSNPVSANVTIPWAYRLLFDEAWVRQAF

Specific function: Catalyzes The Reversible Phosphatidyl Group Transfer From One Phosphatidylglycerol Molecule To Another To Form Cardiolipin (Cl) (Diphosphatidylglycerol) And Glycerol. Affects Resistance To The Gyrase Inhibitor Novobiocin. [C]

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.8.- [C]

Molecular weight: Translated: 40548; Mature: 40548

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRHHAALGTKVRILVTDVLEREKDDAMLHRLAAEFPNVELQEYRWRADHGAPIDEQISQ
CCCCCCCCCCEEEEEEHHHHHCCCHHHHHHHHHHHCCCCCHHHEEEECCCCCCHHHHHHH
LHKTHHIKMLATLAVDPARSRVIIGGRNIHDGFLFHSPIDLSRYPDLQQYGKTDGFSLNY
HHHHHHHEEEEEEEECCCCCEEEECCCCCCCCEEEECCCCCCCCCCHHHHCCCCCEEEEE
YSNWSDFDIEFADRATVETLAAHLSTIWLRDADTNLARPFSIPVRGDGRPRGNARHFISV
ECCCCCCEEEECCHHHHHHHHHHHHHEEEECCCCCCCCCEEEEECCCCCCCCCCCEEEEC
PYEDDHALEGYFVELVDAARRHIQIVNPYLNLTPSLAQAFDRALARGVKIDIVGRIDLKG
CCCCCCCCCHHHHHHHHHHHHHEEEECHHHCCCHHHHHHHHHHHHCCCEEEEEEEEEECC
DIGGKFLTALNRLFVEKYGDRINIREFKAPDVVLHSKIMMIDERLVAISSVNLNNRSFFH
CCCHHHHHHHHHHHHHHCCCCCCEEECCCCCEEHHHHHHHHHHHEEEEEEECCCCCEEEE
DSENGMMVLDPAFYVRMKPIYDDYLAHSNPVSANVTIPWAYRLLFDEAWVRQAF
ECCCCEEEECCEEEEEECCHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIRHHAALGTKVRILVTDVLEREKDDAMLHRLAAEFPNVELQEYRWRADHGAPIDEQISQ
CCCCCCCCCCEEEEEEHHHHHCCCHHHHHHHHHHHCCCCCHHHEEEECCCCCCHHHHHHH
LHKTHHIKMLATLAVDPARSRVIIGGRNIHDGFLFHSPIDLSRYPDLQQYGKTDGFSLNY
HHHHHHHEEEEEEEECCCCCEEEECCCCCCCCEEEECCCCCCCCCCHHHHCCCCCEEEEE
YSNWSDFDIEFADRATVETLAAHLSTIWLRDADTNLARPFSIPVRGDGRPRGNARHFISV
ECCCCCCEEEECCHHHHHHHHHHHHHEEEECCCCCCCCCEEEEECCCCCCCCCCCEEEEC
PYEDDHALEGYFVELVDAARRHIQIVNPYLNLTPSLAQAFDRALARGVKIDIVGRIDLKG
CCCCCCCCCHHHHHHHHHHHHHEEEECHHHCCCHHHHHHHHHHHHCCCEEEEEEEEEECC
DIGGKFLTALNRLFVEKYGDRINIREFKAPDVVLHSKIMMIDERLVAISSVNLNNRSFFH
CCCHHHHHHHHHHHHHHCCCCCCEEECCCCCEEHHHHHHHHHHHEEEEEEECCCCCEEEE
DSENGMMVLDPAFYVRMKPIYDDYLAHSNPVSANVTIPWAYRLLFDEAWVRQAF
ECCCCEEEECCEEEEEECCHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Phosphatidylglycerol [C]

Specific reaction: 2 Phosphatidylglycerol = Biphosphatidylglycerol + Glycerol. [C]

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA