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The map label for this gene is ruvB

Identifier: 13473338

GI number: 13473338

Start: 3132366

End: 3133403

Strand: Reverse

Name: ruvB

Synonym: mll3895

Alternate gene names: 13473338

Gene position: 3133403-3132366 (Counterclockwise)

Preceding gene: 13473339

Following gene: 13473337

Centisome position: 44.53

GC content: 66.38

Gene sequence:

>1038_bases
ATGAGCCTGTCGCCCCGTCTCATTGCGCCGGAAAAACGCGGCGAGGATGCCGATCAGACCTTGCGGCCGCAGACGCTCGC
CGACTTTGTCGGCCAGGCGGCGGTGCGGGCCAATCTCAAAGTCTTCATCGAGGCCGCCAAGGGCCGCAACGAGGCGCTCG
ACCATGTGCTGTTCGTCGGGCCGCCGGGGCTGGGCAAGACGACGCTGGCGCAGATCATGGCGCGCGAACTCGGCGTCAAT
TTCCGCTCGACGTCCGGACCGGTCATCGCCAAGGCCGGCGATCTCGCCGCATTGCTCACCAATCTCGAAGAAGGTGATGT
GCTGTTCATCGACGAGATCCACCGGCTCAATCCTGCGGTGGAGGAAATTCTCTATCCGGCGATGGAGGATTTCCAGCTCG
ACCTGATCATCGGCGAGGGGCCGGCGGCGCGTTCGGTCAAGATCGACCTCGCCCGTTTCACCCTCGTCGCCGCCACCACG
CGACTTGGCCTGCTCACCAATCCGCTGCGCGACCGATTCGGCATTCCGGTGCGGCTCAATTTCTATACGGTCGAGGAACT
GGAGCAGATCGTCCGTCGCGGCGCGCGCATCCTGCAAATGCCGCTCGGCGACGATGGCGCGCTGGAGATCGCGCGGCGCG
CGCGCGGCACGCCGCGCATCGCGGGGCGGTTGCTGCGCCGCGTGCGCGATTTCGCCTCGGTCGCCGGCGACGGCCATGTC
GACCGTCTCATCGCCGACGAGGCGCTGACCCGGCTTGAGGTCGATGCGCTCGGCCTGGACGCGCTCGACCGCCGCTATCT
CTCGATGATCGCCCGCAATTTCGGCGGCGGGCCAGTCGGCATCGAGACGATCGCCGCTGGGCTGTCCGAGCCGCGCGATG
CCATCGAGGACATCATCGAGCCTTATCTGATCCAACAAGGCTTCATCCAGCGCACGCCGCGCGGCCGCATGCTGACGGCC
AACGCCTGGCGCCATCTCGGCCTCGACGCGCCGAAGGATTTGGCGCAGCAGCAGATCAACCTGTTCCAGGAAGAATAG

Upstream 100 bases:

>100_bases
GAGGACGCGGATGCCTCGAAGCTGATCCGCTTCGGGCTGAAGGAACTGGCGCGGTGAGGGCTCGCTTGTCCCTGCTCGTG
CCATATGCCAGGAAGACAGC

Downstream 100 bases:

>100_bases
CGGCCAAGCGATCAGGCTCGGATTTTCAGGCCAGTGATCAAGCATCCGTGAACGGCTTGCGCAAAATCTGCTCGTCTTTG
CCGATTTGCCGGCGCAATCC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MSLSPRLIAPEKRGEDADQTLRPQTLADFVGQAAVRANLKVFIEAAKGRNEALDHVLFVGPPGLGKTTLAQIMARELGVN
FRSTSGPVIAKAGDLAALLTNLEEGDVLFIDEIHRLNPAVEEILYPAMEDFQLDLIIGEGPAARSVKIDLARFTLVAATT
RLGLLTNPLRDRFGIPVRLNFYTVEELEQIVRRGARILQMPLGDDGALEIARRARGTPRIAGRLLRRVRDFASVAGDGHV
DRLIADEALTRLEVDALGLDALDRRYLSMIARNFGGGPVGIETIAAGLSEPRDAIEDIIEPYLIQQGFIQRTPRGRMLTA
NAWRHLGLDAPKDLAQQQINLFQEE

Sequences:

>Translated_345_residues
MSLSPRLIAPEKRGEDADQTLRPQTLADFVGQAAVRANLKVFIEAAKGRNEALDHVLFVGPPGLGKTTLAQIMARELGVN
FRSTSGPVIAKAGDLAALLTNLEEGDVLFIDEIHRLNPAVEEILYPAMEDFQLDLIIGEGPAARSVKIDLARFTLVAATT
RLGLLTNPLRDRFGIPVRLNFYTVEELEQIVRRGARILQMPLGDDGALEIARRARGTPRIAGRLLRRVRDFASVAGDGHV
DRLIADEALTRLEVDALGLDALDRRYLSMIARNFGGGPVGIETIAAGLSEPRDAIEDIIEPYLIQQGFIQRTPRGRMLTA
NAWRHLGLDAPKDLAQQQINLFQEE
>Mature_344_residues
SLSPRLIAPEKRGEDADQTLRPQTLADFVGQAAVRANLKVFIEAAKGRNEALDHVLFVGPPGLGKTTLAQIMARELGVNF
RSTSGPVIAKAGDLAALLTNLEEGDVLFIDEIHRLNPAVEEILYPAMEDFQLDLIIGEGPAARSVKIDLARFTLVAATTR
LGLLTNPLRDRFGIPVRLNFYTVEELEQIVRRGARILQMPLGDDGALEIARRARGTPRIAGRLLRRVRDFASVAGDGHVD
RLIADEALTRLEVDALGLDALDRRYLSMIARNFGGGPVGIETIAAGLSEPRDAIEDIIEPYLIQQGFIQRTPRGRMLTAN
AWRHLGLDAPKDLAQQQINLFQEE

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=316, Percent_Identity=63.9240506329114, Blast_Score=413, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_RHILO (Q98F76)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_104905.1
- ProteinModelPortal:   Q98F76
- SMR:   Q98F76
- GeneID:   1227566
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll3895
- NMPDR:   fig|266835.1.peg.3009
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 37872; Mature: 37741

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSPRLIAPEKRGEDADQTLRPQTLADFVGQAAVRANLKVFIEAAKGRNEALDHVLFVG
CCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCHHEEEEECCCCCHHHCEEEEEC
PPGLGKTTLAQIMARELGVNFRSTSGPVIAKAGDLAALLTNLEEGDVLFIDEIHRLNPAV
CCCCCHHHHHHHHHHHHCCCEECCCCCEEECCCHHHHHHHCCCCCCEEEEHHHHHCCHHH
EEILYPAMEDFQLDLIIGEGPAARSVKIDLARFTLVAATTRLGLLTNPLRDRFGIPVRLN
HHHHHHHHHCCEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHCHHHHHCCCCEEEE
FYTVEELEQIVRRGARILQMPLGDDGALEIARRARGTPRIAGRLLRRVRDFASVAGDGHV
EEEHHHHHHHHHCCCCEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHH
DRLIADEALTRLEVDALGLDALDRRYLSMIARNFGGGPVGIETIAAGLSEPRDAIEDIIE
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHH
PYLIQQGFIQRTPRGRMLTANAWRHLGLDAPKDLAQQQINLFQEE
HHHHHHHHHHCCCCCCEEECCHHHHCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLSPRLIAPEKRGEDADQTLRPQTLADFVGQAAVRANLKVFIEAAKGRNEALDHVLFVG
CCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCHHEEEEECCCCCHHHCEEEEEC
PPGLGKTTLAQIMARELGVNFRSTSGPVIAKAGDLAALLTNLEEGDVLFIDEIHRLNPAV
CCCCCHHHHHHHHHHHHCCCEECCCCCEEECCCHHHHHHHCCCCCCEEEEHHHHHCCHHH
EEILYPAMEDFQLDLIIGEGPAARSVKIDLARFTLVAATTRLGLLTNPLRDRFGIPVRLN
HHHHHHHHHCCEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHCHHHHHCCCCEEEE
FYTVEELEQIVRRGARILQMPLGDDGALEIARRARGTPRIAGRLLRRVRDFASVAGDGHV
EEEHHHHHHHHHCCCCEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHH
DRLIADEALTRLEVDALGLDALDRRYLSMIARNFGGGPVGIETIAAGLSEPRDAIEDIIE
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHH
PYLIQQGFIQRTPRGRMLTANAWRHLGLDAPKDLAQQQINLFQEE
HHHHHHHHHHCCCCCCEEECCHHHHCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968