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The map label for this gene is tolQ [H]

Identifier: 13473333

GI number: 13473333

Start: 3128376

End: 3129086

Strand: Reverse

Name: tolQ [H]

Synonym: mll3891

Alternate gene names: 13473333

Gene position: 3129086-3128376 (Counterclockwise)

Preceding gene: 13473335

Following gene: 13473332

Centisome position: 44.47

GC content: 63.99

Gene sequence:

>711_bases
ATGGAAAATATCGCACTCGCCGATCCGGGCGCGCAATTGTCGATTTGGGCGCTGTTCATGCAGGCCAGCTGGGTGGTCAA
GCTGGTCATGATCGGGCTGCTCTGCGCCTCGGTCTGGACCTGGGCGATCATCATCGACAAGCTGGTTGCCTATGGCCGCA
TGCGGCTAGCGCTGAACCGCTTCGAGCAGGTCTTCTGGTCCGGGCAGTCGCTGGAAGAGCTCTACCGCACGCTCGCCGAC
CGCAAGACATCAGGCATGGGCGCCATTTTCGTCGCCGCCATGCGCGAGTGGAAGAAGAGCTTCGAGAAGGGCGCCAAGAC
GCCGCTCGGGCTGCAGACCCGCATCGACAAGGCGATGGACCTGGCGCTGACCCGCGAGATGGAGAAGCTGGAGGGCCGCC
TCGGCTTTCTCGCCACCACGGGCTCGGCGGCGCCGTTCATCGGTCTGTTCGGGACGGTCATCGGCATCATGACCTCGTTC
CAGGCCATTGCCGGCTCCAAGAACACTAGTCTCGCGGTTGTCGCGCCCGGCATCGCCGAGGCGCTGCTGGCGACGGCCAT
CGGCCTGCTCGCCGCCATCCCGGCCGTCATTGCCTACAACAAGCTGTCATCGGATGCGAGCAAGCTCGCGGTGCGCATGG
AAGGGTTCTCCGACGAGTTCTCCGCCATACTCTCGCGCCAAATCGATGAAAAAGTCGCGCCGAAGGCCTGA

Upstream 100 bases:

>100_bases
ACGGCACGGTTTGGGGCGTCCGGTAGCTTCGTGCGAACCGACCACAAGGGATGCCAGGGGCCAGCTGCCAGCTTCGCCCG
GAAATCTTAAGGACGTAACG

Downstream 100 bases:

>100_bases
GGAGTAGCTGATGGGTATGTCCGTAGGCATGGCGGGACGCGGCGGGCGCGGCCACAGGCGGCGCGGCCGTCATCATGGGC
TGATGTCGGAAATCAACGTC

Product: TolQ protein, inner membrane protein, tolerance to group A colicins

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MENIALADPGAQLSIWALFMQASWVVKLVMIGLLCASVWTWAIIIDKLVAYGRMRLALNRFEQVFWSGQSLEELYRTLAD
RKTSGMGAIFVAAMREWKKSFEKGAKTPLGLQTRIDKAMDLALTREMEKLEGRLGFLATTGSAAPFIGLFGTVIGIMTSF
QAIAGSKNTSLAVVAPGIAEALLATAIGLLAAIPAVIAYNKLSSDASKLAVRMEGFSDEFSAILSRQIDEKVAPKA

Sequences:

>Translated_236_residues
MENIALADPGAQLSIWALFMQASWVVKLVMIGLLCASVWTWAIIIDKLVAYGRMRLALNRFEQVFWSGQSLEELYRTLAD
RKTSGMGAIFVAAMREWKKSFEKGAKTPLGLQTRIDKAMDLALTREMEKLEGRLGFLATTGSAAPFIGLFGTVIGIMTSF
QAIAGSKNTSLAVVAPGIAEALLATAIGLLAAIPAVIAYNKLSSDASKLAVRMEGFSDEFSAILSRQIDEKVAPKA
>Mature_236_residues
MENIALADPGAQLSIWALFMQASWVVKLVMIGLLCASVWTWAIIIDKLVAYGRMRLALNRFEQVFWSGQSLEELYRTLAD
RKTSGMGAIFVAAMREWKKSFEKGAKTPLGLQTRIDKAMDLALTREMEKLEGRLGFLATTGSAAPFIGLFGTVIGIMTSF
QAIAGSKNTSLAVVAPGIAEALLATAIGLLAAIPAVIAYNKLSSDASKLAVRMEGFSDEFSAILSRQIDEKVAPKA

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=217, Percent_Identity=42.3963133640553, Blast_Score=167, Evalue=4e-43,
Organism=Escherichia coli, GI1789381, Length=193, Percent_Identity=44.0414507772021, Blast_Score=138, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 25480; Mature: 25480

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENIALADPGAQLSIWALFMQASWVVKLVMIGLLCASVWTWAIIIDKLVAYGRMRLALNR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEQVFWSGQSLEELYRTLADRKTSGMGAIFVAAMREWKKSFEKGAKTPLGLQTRIDKAMD
HHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LALTREMEKLEGRLGFLATTGSAAPFIGLFGTVIGIMTSFQAIAGSKNTSLAVVAPGIAE
HHHHHHHHHHHCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHH
ALLATAIGLLAAIPAVIAYNKLSSDASKLAVRMEGFSDEFSAILSRQIDEKVAPKA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MENIALADPGAQLSIWALFMQASWVVKLVMIGLLCASVWTWAIIIDKLVAYGRMRLALNR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEQVFWSGQSLEELYRTLADRKTSGMGAIFVAAMREWKKSFEKGAKTPLGLQTRIDKAMD
HHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LALTREMEKLEGRLGFLATTGSAAPFIGLFGTVIGIMTSFQAIAGSKNTSLAVVAPGIAE
HHHHHHHHHHHCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHH
ALLATAIGLLAAIPAVIAYNKLSSDASKLAVRMEGFSDEFSAILSRQIDEKVAPKA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]