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The map label for this gene is malE [C]

Identifier: 13473140

GI number: 13473140

Start: 2937808

End: 2939046

Strand: Direct

Name: malE [C]

Synonym: mlr3639

Alternate gene names: 13473140

Gene position: 2937808-2939046 (Clockwise)

Preceding gene: 13473137

Following gene: 13473141

Centisome position: 41.75

GC content: 61.26

Gene sequence:

>1239_bases
ATGCTTAGGACAATCACCAAAACACTGGTCGGCGCGGTCTTCGCCGGAGGACTGCTAGTCCCGCACGCTTTTGCCGAAAC
GACGCTCAATGCGCTGTTCATGGCGCAGGCCGCCTACAGCGAGGCCGATGTGCGCGCCATGACGGACGCCTTCACCAAGG
CCAATCCGGACGTCAAGGTCAATCTCGAATTCGTTCCCTATGAAGGCCTGCACGACAAGACGGTGCTCGCCCAGGGTTCG
GGCGGCGGCTACGACGTCGTGTTGTTCGACGTCATCTGGCCGGCCGAATACGCCACCAACAAGGTGCTGGTCGACGTCTC
GTCGAAGATCACCGACGATATGAAGAAAGGCGTGCTGCCCGGCGCCTGGACCACGGTGCAGTATGACGGCAAATACTATG
GCATGCCGTGGATTCTCGACACCAAATATCTGTTCTACAACAAGGACATCCTGGAAAAGGCCGGTATCAAGACGCCGCCG
AAGACCTGGGAAGAGCTTGGCGCGCAGGCCAAGATCATCCAGGACAAGGGCCTGCTGAAGACACCGATCGCCTGGAGCTG
GTCGCAGGCCGAAGCCGCGATCTGCGACTATACCACGCTGGTCAGCGCCTATGGCGGCGACTTCCTCAAGGACGGCAAGC
CGGACTTCCAGAATGGCGGCGGCCTCTCGGCGCTGAAATACATGGTCGACAGCTACAAGTCCGGCCTCACCAACCCGAAT
TCCAAGGAATTCCTGGAAGAGGACGTGCGCAAGGTCTTCGAAAACGGCGACGCCGCCTTCGCGCTGAACTGGACCTACAT
GTATAACATGGCCAACGATCCGAAGGACTCGAAGGTGGCCGGCAAGGTCGGCGTCGTGCCGGCGCCGGGCGTCACCGGCA
TCAGCGAGGTGTCGGCCGTCAACGGCTCGATGGGCCTTGGCGTCACCGCGGTCTCGAAGCATCCGGACGAAGCCTGGAAA
TACATCGAATACATGACTTCGCAGGCGACGCAGAACCAGTATGCCAAGCTGTCGCTGCCGATCTGGGCCTCGTCCTATGA
CGACCCGGCCGTCACCAAGGGCCAGGAAGAACTGATCGCCGCCGCCAAGCTCGGCCTCGCCGCCATGTATCCGCGTCCGA
CCACACCGAAATACCAGGAACTGTCGACCGCGCTGCAGCAGGCCATCCAGGAATCGCTGCTCGGCCAATCCTCGCCGGAA
GACGCCCTGAAGACCGCCGCACAAAACAGCGGCCTCTGA

Upstream 100 bases:

>100_bases
GGTCAGCCGGGTAAGCATCAGGTCACGCGACATGGATCAGGGAAGGCGATGCGACATGCGCGTATCGCCGGCCCGTCAAC
ACCGGAAATGGGAGAAGAAG

Downstream 100 bases:

>100_bases
GCACTAGTCTCCAGTTGCGGGCGGCACTACAGCGCCGAGCGTCCCTTGGACGCGCAAAGGACGCTGTAGCGCTTTTGATC
TTGCGCATGATCCTTTCCGG

Product: trehalose/maltose binding protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MLRTITKTLVGAVFAGGLLVPHAFAETTLNALFMAQAAYSEADVRAMTDAFTKANPDVKVNLEFVPYEGLHDKTVLAQGS
GGGYDVVLFDVIWPAEYATNKVLVDVSSKITDDMKKGVLPGAWTTVQYDGKYYGMPWILDTKYLFYNKDILEKAGIKTPP
KTWEELGAQAKIIQDKGLLKTPIAWSWSQAEAAICDYTTLVSAYGGDFLKDGKPDFQNGGGLSALKYMVDSYKSGLTNPN
SKEFLEEDVRKVFENGDAAFALNWTYMYNMANDPKDSKVAGKVGVVPAPGVTGISEVSAVNGSMGLGVTAVSKHPDEAWK
YIEYMTSQATQNQYAKLSLPIWASSYDDPAVTKGQEELIAAAKLGLAAMYPRPTTPKYQELSTALQQAIQESLLGQSSPE
DALKTAAQNSGL

Sequences:

>Translated_412_residues
MLRTITKTLVGAVFAGGLLVPHAFAETTLNALFMAQAAYSEADVRAMTDAFTKANPDVKVNLEFVPYEGLHDKTVLAQGS
GGGYDVVLFDVIWPAEYATNKVLVDVSSKITDDMKKGVLPGAWTTVQYDGKYYGMPWILDTKYLFYNKDILEKAGIKTPP
KTWEELGAQAKIIQDKGLLKTPIAWSWSQAEAAICDYTTLVSAYGGDFLKDGKPDFQNGGGLSALKYMVDSYKSGLTNPN
SKEFLEEDVRKVFENGDAAFALNWTYMYNMANDPKDSKVAGKVGVVPAPGVTGISEVSAVNGSMGLGVTAVSKHPDEAWK
YIEYMTSQATQNQYAKLSLPIWASSYDDPAVTKGQEELIAAAKLGLAAMYPRPTTPKYQELSTALQQAIQESLLGQSSPE
DALKTAAQNSGL
>Mature_412_residues
MLRTITKTLVGAVFAGGLLVPHAFAETTLNALFMAQAAYSEADVRAMTDAFTKANPDVKVNLEFVPYEGLHDKTVLAQGS
GGGYDVVLFDVIWPAEYATNKVLVDVSSKITDDMKKGVLPGAWTTVQYDGKYYGMPWILDTKYLFYNKDILEKAGIKTPP
KTWEELGAQAKIIQDKGLLKTPIAWSWSQAEAAICDYTTLVSAYGGDFLKDGKPDFQNGGGLSALKYMVDSYKSGLTNPN
SKEFLEEDVRKVFENGDAAFALNWTYMYNMANDPKDSKVAGKVGVVPAPGVTGISEVSAVNGSMGLGVTAVSKHPDEAWK
YIEYMTSQATQNQYAKLSLPIWASSYDDPAVTKGQEELIAAAKLGLAAMYPRPTTPKYQELSTALQQAIQESLLGQSSPE
DALKTAAQNSGL

Specific function: Probably part of a binding-protein-dependent transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790466, Length=358, Percent_Identity=24.0223463687151, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 720 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006059 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: NA

Molecular weight: Translated: 44651; Mature: 44651

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRTITKTLVGAVFAGGLLVPHAFAETTLNALFMAQAAYSEADVRAMTDAFTKANPDVKV
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEE
NLEFVPYEGLHDKTVLAQGSGGGYDVVLFDVIWPAEYATNKVLVDVSSKITDDMKKGVLP
EEEEECCCCCCCCEEEEECCCCCEEEEEEEEECCHHHCCCEEEEECHHHHHHHHHHCCCC
GAWTTVQYDGKYYGMPWILDTKYLFYNKDILEKAGIKTPPKTWEELGAQAKIIQDKGLLK
CCEEEEEECCEEECCCEEEECEEEEECHHHHHHCCCCCCCHHHHHCCCCEEEECCCCCEE
TPIAWSWSQAEAAICDYTTLVSAYGGDFLKDGKPDFQNGGGLSALKYMVDSYKSGLTNPN
CCCCCCCCCCCHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
SKEFLEEDVRKVFENGDAAFALNWTYMYNMANDPKDSKVAGKVGVVPAPGVTGISEVSAV
HHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHC
NGSMGLGVTAVSKHPDEAWKYIEYMTSQATQNQYAKLSLPIWASSYDDPAVTKGQEELIA
CCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCHHHHHH
AAKLGLAAMYPRPTTPKYQELSTALQQAIQESLLGQSSPEDALKTAAQNSGL
HHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MLRTITKTLVGAVFAGGLLVPHAFAETTLNALFMAQAAYSEADVRAMTDAFTKANPDVKV
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEE
NLEFVPYEGLHDKTVLAQGSGGGYDVVLFDVIWPAEYATNKVLVDVSSKITDDMKKGVLP
EEEEECCCCCCCCEEEEECCCCCEEEEEEEEECCHHHCCCEEEEECHHHHHHHHHHCCCC
GAWTTVQYDGKYYGMPWILDTKYLFYNKDILEKAGIKTPPKTWEELGAQAKIIQDKGLLK
CCEEEEEECCEEECCCEEEECEEEEECHHHHHHCCCCCCCHHHHHCCCCEEEECCCCCEE
TPIAWSWSQAEAAICDYTTLVSAYGGDFLKDGKPDFQNGGGLSALKYMVDSYKSGLTNPN
CCCCCCCCCCCHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
SKEFLEEDVRKVFENGDAAFALNWTYMYNMANDPKDSKVAGKVGVVPAPGVTGISEVSAV
HHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHC
NGSMGLGVTAVSKHPDEAWKYIEYMTSQATQNQYAKLSLPIWASSYDDPAVTKGQEELIA
CCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCHHHHHH
AAKLGLAAMYPRPTTPKYQELSTALQQAIQESLLGQSSPEDALKTAAQNSGL
HHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]