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The map label for this gene is aroK

Identifier: 13473083

GI number: 13473083

Start: 2879337

End: 2879948

Strand: Reverse

Name: aroK

Synonym: mll3573

Alternate gene names: 13473083

Gene position: 2879948-2879337 (Counterclockwise)

Preceding gene: 13473089

Following gene: 13473082

Centisome position: 40.93

GC content: 65.85

Gene sequence:

>612_bases
ATGAACGCGCACCAGGCAAATCCCCCAGGCGAGAGCCTCGCCGCGCTGCTTGGCCGGCTGGGCAGCCGGTCCATCGTCTT
TGTCGGCCTGATGGGCGCCGGCAAGACGGCGATCGGGCGCAAGGTGGCGACGATGCTTTCGCTGCCTTTCATCGACAGCG
ACCAGGAGATCGAGAGCGTCTCGCGCATGACCGTGCCGGAGCTGTTCGAGCGCTATGGCGAGGCCGAGTTCAGGGCCCTG
GAGCAGCGCGTCATCCTGCGCGTGCTGGAAAATGGCCCGCAGGTGCTGTCGACCGGCGGCGGCGCCTTCATGAACGCGCA
GACGCGCGAGGCCATCGCCGGCCATGGCGTGTCGGTGTGGCTGAAGGCCGAGCTCGACCTTCTGATGGACCGGGTCTCGA
AGAAGCAGAACCGGCCGCTGTTGAAGAGTGCCGATCCTCGCGCCGTGCTGGAGCGGCTGATGAGCGAGCGGTATCCGGTC
TACGCGACATCGGATGTCACCGTGCCGACCCGCGACGACCGCAAGGAAGTCATCGCTGCCGAGGTGCTGAATGCGCTGTG
CCGGCATTTCGGCATCGATGAAATTGCAGCGACGGGCGAGATCGAATCGTGA

Upstream 100 bases:

>100_bases
GCATCCTCCACCCGATATAGGCTTGCCTATGCTCGGCACGCTTGACGCAAACCGGCTTTTCATGTCGATACGCCGGCAAA
GAGGGCCCAAGAAACAGCTG

Downstream 100 bases:

>100_bases
GCGCGGACCAGCCAGTCACCGTCGAAGTCGGCCTTGGCGACCGGGCCTACGACATATTGATCGGCTCCGGCCTTTTGTCG
CGCGCCGGCGAAGAGATTTC

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MNAHQANPPGESLAALLGRLGSRSIVFVGLMGAGKTAIGRKVATMLSLPFIDSDQEIESVSRMTVPELFERYGEAEFRAL
EQRVILRVLENGPQVLSTGGGAFMNAQTREAIAGHGVSVWLKAELDLLMDRVSKKQNRPLLKSADPRAVLERLMSERYPV
YATSDVTVPTRDDRKEVIAAEVLNALCRHFGIDEIAATGEIES

Sequences:

>Translated_203_residues
MNAHQANPPGESLAALLGRLGSRSIVFVGLMGAGKTAIGRKVATMLSLPFIDSDQEIESVSRMTVPELFERYGEAEFRAL
EQRVILRVLENGPQVLSTGGGAFMNAQTREAIAGHGVSVWLKAELDLLMDRVSKKQNRPLLKSADPRAVLERLMSERYPV
YATSDVTVPTRDDRKEVIAAEVLNALCRHFGIDEIAATGEIES
>Mature_203_residues
MNAHQANPPGESLAALLGRLGSRSIVFVGLMGAGKTAIGRKVATMLSLPFIDSDQEIESVSRMTVPELFERYGEAEFRAL
EQRVILRVLENGPQVLSTGGGAFMNAQTREAIAGHGVSVWLKAELDLLMDRVSKKQNRPLLKSADPRAVLERLMSERYPV
YATSDVTVPTRDDRKEVIAAEVLNALCRHFGIDEIAATGEIES

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

Organism=Escherichia coli, GI87082255, Length=167, Percent_Identity=40.1197604790419, Blast_Score=117, Evalue=4e-28,
Organism=Escherichia coli, GI1786587, Length=171, Percent_Identity=28.0701754385965, Blast_Score=67, Evalue=7e-13,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): AROK_RHILO (Q98FY0)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_104650.1
- ProteinModelPortal:   Q98FY0
- SMR:   Q98FY0
- GeneID:   1227311
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll3573
- NMPDR:   fig|266835.1.peg.2754
- HOGENOM:   HBG335815
- OMA:   VIYLRAN
- BRENDA:   2.7.1.71
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR000623
- InterPro:   IPR023000
- PRINTS:   PR01100

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 22162; Mature: 22162

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS01128 SHIKIMATE_KINASE; PS00267 TACHYKININ

Important sites: BINDING 54-54 BINDING 78-78 BINDING 100-100 BINDING 138-138 BINDING 157-157

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAHQANPPGESLAALLGRLGSRSIVFVGLMGAGKTAIGRKVATMLSLPFIDSDQEIESV
CCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHH
SRMTVPELFERYGEAEFRALEQRVILRVLENGPQVLSTGGGAFMNAQTREAIAGHGVSVW
HHCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEECCHHHHHHHCCCEEEE
LKAELDLLMDRVSKKQNRPLLKSADPRAVLERLMSERYPVYATSDVTVPTRDDRKEVIAA
EHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHH
EVLNALCRHFGIDEIAATGEIES
HHHHHHHHHCCHHHHHCCCCCCC
>Mature Secondary Structure
MNAHQANPPGESLAALLGRLGSRSIVFVGLMGAGKTAIGRKVATMLSLPFIDSDQEIESV
CCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHH
SRMTVPELFERYGEAEFRALEQRVILRVLENGPQVLSTGGGAFMNAQTREAIAGHGVSVW
HHCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEECCHHHHHHHCCCEEEE
LKAELDLLMDRVSKKQNRPLLKSADPRAVLERLMSERYPVYATSDVTVPTRDDRKEVIAA
EHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHH
EVLNALCRHFGIDEIAATGEIES
HHHHHHHHHCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968