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The map label for this gene is ltrA [H]

Identifier: 13473070

GI number: 13473070

Start: 2866990

End: 2867925

Strand: Direct

Name: ltrA [H]

Synonym: mlr3557

Alternate gene names: 13473070

Gene position: 2866990-2867925 (Clockwise)

Preceding gene: 13473068

Following gene: 13473078

Centisome position: 40.75

GC content: 64.1

Gene sequence:

>936_bases
ATGAACAACACTGTAGCCAAGAAGGAAACGATATCGCTGGCCGACCTAGCCCTCTTTCTCGAGGTCGCGCGCCAGGGCTC
GCTGACCAGGGCTGCCTTGCAAGCGGGTACGACTAAGAGCGCCGTGTCGAAGGCTATCCGGCGGCTGGAGTTGCGGCTGG
GATGCGTCTTGCTTGAGCGCACCACGCGACGTCTTATCGTCACACCTGCCGGCGAGCTGTTATGCCAGCGCGGGCAGGCC
CTGCTGGGCGACGTCGATGACCTGGCGCAAGCCCTGGAGGCGCAGGCCGACGGGCTCGCGGGCCCCTTGTGCATTTGCGC
GCCGCCCGAACTCGGCGCCTGGCTTCTGCAGACGTGTTTTGCACCGTTCCTGGAGTTGCATCCCCGTATCCGTCTCGCTC
TTCGCCTCGACTATGCCTATCAGGATCTGTTCGATCCCCACCTCGACCTTACGTTCCGTGTCGGGGCAATCGTCGACGAC
GCCATGGTCGCGCGCCGCGTCGGCCAATTCCGGCGGGTGCTCGTCGCGAACCGGGCCATCGCCGATAGCCTGGCCGGCAA
GGACCTGGCAACCGTGGCCAGGACTTTGCCCATGCTGGCTTTCGGCGATGGGGAAAGCGAGCTTGCCTTGTCGCGCGAGG
CCGAAATCGCCACAATCACGGTTCGCTCGGACCGGTTCAGCGCCAACACCTATCCTGCCTTGCTCGAAGCTGCCACGCAG
GGCCTGGGCATCGCCGTCCTGCCCGATTTCTTCGTGCAGCGGCATGTCGAATCCGGCTCCGTCGTCCGGCTCTTTGCCGA
TTGGCAGTCCACGGACATACCAATCTATGTCATCCATCGCCGCGCCAGCCGTCGATCGCGGCGAGCCGAAGCCTTGCTGT
CCTTTATTGGGCCGGAACTGGTGGGCCTGTCAGAATTGGCCGCTCCACTGAAGTGA

Upstream 100 bases:

>100_bases
TTTTGAGCACGATACGGCGATTCAGCATGATGACGACACTCCGATTGACAGGTTGGCCCGCACCATATTTTGTTTCCAGA
AAACGATAAAGTGAGGCCTC

Downstream 100 bases:

>100_bases
GACATTCACGACGGAGATCATCGGCATCCTGCGCGAGGCCGAAAAGCGGGCCGCCTCGCCACCAACGGCTCACGTCCTTG
ATCGGAAGCCGGGGCAGCGA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MNNTVAKKETISLADLALFLEVARQGSLTRAALQAGTTKSAVSKAIRRLELRLGCVLLERTTRRLIVTPAGELLCQRGQA
LLGDVDDLAQALEAQADGLAGPLCICAPPELGAWLLQTCFAPFLELHPRIRLALRLDYAYQDLFDPHLDLTFRVGAIVDD
AMVARRVGQFRRVLVANRAIADSLAGKDLATVARTLPMLAFGDGESELALSREAEIATITVRSDRFSANTYPALLEAATQ
GLGIAVLPDFFVQRHVESGSVVRLFADWQSTDIPIYVIHRRASRRSRRAEALLSFIGPELVGLSELAAPLK

Sequences:

>Translated_311_residues
MNNTVAKKETISLADLALFLEVARQGSLTRAALQAGTTKSAVSKAIRRLELRLGCVLLERTTRRLIVTPAGELLCQRGQA
LLGDVDDLAQALEAQADGLAGPLCICAPPELGAWLLQTCFAPFLELHPRIRLALRLDYAYQDLFDPHLDLTFRVGAIVDD
AMVARRVGQFRRVLVANRAIADSLAGKDLATVARTLPMLAFGDGESELALSREAEIATITVRSDRFSANTYPALLEAATQ
GLGIAVLPDFFVQRHVESGSVVRLFADWQSTDIPIYVIHRRASRRSRRAEALLSFIGPELVGLSELAAPLK
>Mature_311_residues
MNNTVAKKETISLADLALFLEVARQGSLTRAALQAGTTKSAVSKAIRRLELRLGCVLLERTTRRLIVTPAGELLCQRGQA
LLGDVDDLAQALEAQADGLAGPLCICAPPELGAWLLQTCFAPFLELHPRIRLALRLDYAYQDLFDPHLDLTFRVGAIVDD
AMVARRVGQFRRVLVANRAIADSLAGKDLATVARTLPMLAFGDGESELALSREAEIATITVRSDRFSANTYPALLEAATQ
GLGIAVLPDFFVQRHVESGSVVRLFADWQSTDIPIYVIHRRASRRSRRAEALLSFIGPELVGLSELAAPLK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787589, Length=286, Percent_Identity=29.3706293706294, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786401, Length=294, Percent_Identity=27.891156462585, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI145693193, Length=292, Percent_Identity=27.0547945205479, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789639, Length=297, Percent_Identity=25.9259259259259, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87081978, Length=259, Percent_Identity=26.6409266409266, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787128, Length=275, Percent_Identity=25.4545454545455, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790399, Length=131, Percent_Identity=29.7709923664122, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789440, Length=292, Percent_Identity=22.9452054794521, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788481, Length=147, Percent_Identity=31.2925170068027, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33851; Mature: 33851

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNTVAKKETISLADLALFLEVARQGSLTRAALQAGTTKSAVSKAIRRLELRLGCVLLER
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEC
TTRRLIVTPAGELLCQRGQALLGDVDDLAQALEAQADGLAGPLCICAPPELGAWLLQTCF
CCCEEEECCHHHHHHHCCHHHHCCHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHH
APFLELHPRIRLALRLDYAYQDLFDPHLDLTFRVGAIVDDAMVARRVGQFRRVLVANRAI
HHHHHHCCCEEEEEEECHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
ADSLAGKDLATVARTLPMLAFGDGESELALSREAEIATITVRSDRFSANTYPALLEAATQ
HHHHCCCHHHHHHHHHHHEEECCCCCCEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHC
GLGIAVLPDFFVQRHVESGSVVRLFADWQSTDIPIYVIHRRASRRSRRAEALLSFIGPEL
CCCEEEHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECHHHHHHHHHHHHHHHHCHHH
VGLSELAAPLK
CCHHHHCCCCC
>Mature Secondary Structure
MNNTVAKKETISLADLALFLEVARQGSLTRAALQAGTTKSAVSKAIRRLELRLGCVLLER
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEC
TTRRLIVTPAGELLCQRGQALLGDVDDLAQALEAQADGLAGPLCICAPPELGAWLLQTCF
CCCEEEECCHHHHHHHCCHHHHCCHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHH
APFLELHPRIRLALRLDYAYQDLFDPHLDLTFRVGAIVDDAMVARRVGQFRRVLVANRAI
HHHHHHCCCEEEEEEECHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
ADSLAGKDLATVARTLPMLAFGDGESELALSREAEIATITVRSDRFSANTYPALLEAATQ
HHHHCCCHHHHHHHHHHHEEECCCCCCEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHC
GLGIAVLPDFFVQRHVESGSVVRLFADWQSTDIPIYVIHRRASRRSRRAEALLSFIGPEL
CCCEEEHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECHHHHHHHHHHHHHHHHCHHH
VGLSELAAPLK
CCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]