Click here to switch to the map view.

The map label for this gene is glcK [H]

Identifier: 13472953

GI number: 13472953

Start: 2739829

End: 2741277

Strand: Direct

Name: glcK [H]

Synonym: mlr3412

Alternate gene names: 13472953

Gene position: 2739829-2741277 (Clockwise)

Preceding gene: 13472952

Following gene: 13472955

Centisome position: 38.94

GC content: 68.05

Gene sequence:

>1449_bases
ATGCAGGACGGCATGCCTCTCAGCATAGGAATAGATATCGGCGGCACCAATCTGCGTGCCGCCCGCATTTCCGGCACCGG
TGAAATCATCAAGCGCGTTTCCGAAAAAAGCGCGCCGGACCCGGAGCTGGTGCTCGGCCGCATCGCCGACATGGTGCGCC
TTCTCGACACGCCGGATGTGAAGGCCATCGGCGTCGGCGTTCCAGGCCGCGTCGATGCGCGGCGCGGCGCGGTGCTGTCG
GGCGGCTATGTCAACCTCGCCTCGGTCGCGCTGGCGCAGCGCCTGGAAGACATGACAGGCAAGCCTGTCATCATCGACAA
CGACTGCAACATGGCGCTGGCCGCCGAGATGGCGCTCGGCGCCGGGCGCGGCCATGGCAACATCGTCATGTTCACCATCG
GCACCGGCATTGGCGGCGCCGTCGCCCAGGATCGGCGGATCACGCGTGGTTCGGCAACGGCGGGCCAGCTCGGCCACATC
ACCGTCGACGTCAATGGCGAGGTCTGCGCCTGCGGCCGGCGCGGCTGCGTCGAAACCACCAGTTCGGGCACCGCGCTCGG
CCGTCACATTGCGCGCGCCGGGCTCGGCACCGACATTTCGGTCGATCAGCTCTTTGCCCGCGATGCAGCCGGCGATATTC
AGGCGCGCGGCGTACTGGACGCCTGGGCGAAACCGCTGCGGGCCGCCATCGACACCGCCGTTGCCATGCTTGCTCCCGAT
TTGGTGCTGCTTGGCGGCGGCCTTGGCCGGGCGGCCCATGCAGCACTCGGCCGAGCGCCGGCGCTGGCACCCTGGTACCA
ATGCCAGGTCGAAGCAGCACAACTCGGTGACGATGCCGGCGTGATCGGCGCCGGCCTCCAGGCCCTGGCGGCGGAACCGC
ACCTTTCGCCCTCGACCCAGTCCAGCCGCCCGCTTCGCGCCGTGCTCGTCAACGGCATCCCCGCCAGCGGCAAGAGCACC
GTCTCGCGCGGCATCGCCGATCGCATGGACTGGCCGCTGTTGGCGCTCGACACGATCAAGAACCCCTTCCTCGAAGTACT
CGGCGGCGGCGACCGCCTGTTCAACCGCACGCTCGGCCGCGCCAGCTACCAGGCAATCTGGTCGGTCGTCGGCGAAGCCC
CTGCCGGCACCACCTTCATCGTCGATGCCTGGTTCGGCTTCCAGCCGCGGGAGGTTCTCGAGGATCATCTGAGAAAGGCA
GGCGTCGAGCAGACTTTCGAAATCTGGTGCCATGCACCAGGCGAGGTGCTCGCCGAGCGCTACGGCGCCCGGCTCGACCT
GCGTCCCGCCGGCCATCCCGGTGCGGCCTATATCCCCGAATTGATCGAACTCGCCAAACGCGCCGAGCCGCTGCGGCGCG
GACCGTTCTTCGACGTCGACACGACGAAACCGATCGACTTCGATACCATCACGGCCTGGTTGCGAGCGACGATGGACGGC
CGCGCATAG

Upstream 100 bases:

>100_bases
CCACTACCGGCAGAAAGCCGCTGCCTGACAGTTGCGTTGGACGAGAGCTGTTCCAGCGAAAGTGTGAAGCGGCTTTGCGT
CCGGAATTGCGCGAAAACAG

Downstream 100 bases:

>100_bases
ACAGTCGGACGGCCCGTTCAGTCGCCACTGCAGACGTGAAGTTCCGTTCCGGCTGCTTCGATGACCGCGCGCAGCGCCGG
TTGCGGTTCACGATCGGTGA

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MQDGMPLSIGIDIGGTNLRAARISGTGEIIKRVSEKSAPDPELVLGRIADMVRLLDTPDVKAIGVGVPGRVDARRGAVLS
GGYVNLASVALAQRLEDMTGKPVIIDNDCNMALAAEMALGAGRGHGNIVMFTIGTGIGGAVAQDRRITRGSATAGQLGHI
TVDVNGEVCACGRRGCVETTSSGTALGRHIARAGLGTDISVDQLFARDAAGDIQARGVLDAWAKPLRAAIDTAVAMLAPD
LVLLGGGLGRAAHAALGRAPALAPWYQCQVEAAQLGDDAGVIGAGLQALAAEPHLSPSTQSSRPLRAVLVNGIPASGKST
VSRGIADRMDWPLLALDTIKNPFLEVLGGGDRLFNRTLGRASYQAIWSVVGEAPAGTTFIVDAWFGFQPREVLEDHLRKA
GVEQTFEIWCHAPGEVLAERYGARLDLRPAGHPGAAYIPELIELAKRAEPLRRGPFFDVDTTKPIDFDTITAWLRATMDG
RA

Sequences:

>Translated_482_residues
MQDGMPLSIGIDIGGTNLRAARISGTGEIIKRVSEKSAPDPELVLGRIADMVRLLDTPDVKAIGVGVPGRVDARRGAVLS
GGYVNLASVALAQRLEDMTGKPVIIDNDCNMALAAEMALGAGRGHGNIVMFTIGTGIGGAVAQDRRITRGSATAGQLGHI
TVDVNGEVCACGRRGCVETTSSGTALGRHIARAGLGTDISVDQLFARDAAGDIQARGVLDAWAKPLRAAIDTAVAMLAPD
LVLLGGGLGRAAHAALGRAPALAPWYQCQVEAAQLGDDAGVIGAGLQALAAEPHLSPSTQSSRPLRAVLVNGIPASGKST
VSRGIADRMDWPLLALDTIKNPFLEVLGGGDRLFNRTLGRASYQAIWSVVGEAPAGTTFIVDAWFGFQPREVLEDHLRKA
GVEQTFEIWCHAPGEVLAERYGARLDLRPAGHPGAAYIPELIELAKRAEPLRRGPFFDVDTTKPIDFDTITAWLRATMDG
RA
>Mature_482_residues
MQDGMPLSIGIDIGGTNLRAARISGTGEIIKRVSEKSAPDPELVLGRIADMVRLLDTPDVKAIGVGVPGRVDARRGAVLS
GGYVNLASVALAQRLEDMTGKPVIIDNDCNMALAAEMALGAGRGHGNIVMFTIGTGIGGAVAQDRRITRGSATAGQLGHI
TVDVNGEVCACGRRGCVETTSSGTALGRHIARAGLGTDISVDQLFARDAAGDIQARGVLDAWAKPLRAAIDTAVAMLAPD
LVLLGGGLGRAAHAALGRAPALAPWYQCQVEAAQLGDDAGVIGAGLQALAAEPHLSPSTQSSRPLRAVLVNGIPASGKST
VSRGIADRMDWPLLALDTIKNPFLEVLGGGDRLFNRTLGRASYQAIWSVVGEAPAGTTFIVDAWFGFQPREVLEDHLRKA
GVEQTFEIWCHAPGEVLAERYGARLDLRPAGHPGAAYIPELIELAKRAEPLRRGPFFDVDTTKPIDFDTITAWLRATMDG
RA

Specific function: May Be A Regulator In Specific Sugar Metabolism. May Influence The Rate Of Glucose Uptake Or Glycolysis In Cells In The Rich Medium. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=267, Percent_Identity=32.5842696629214, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI190014632, Length=272, Percent_Identity=32.7205882352941, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI4885285, Length=267, Percent_Identity=32.5842696629214, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI298566315, Length=267, Percent_Identity=32.5842696629214, Blast_Score=99, Evalue=7e-21,
Organism=Escherichia coli, GI1787878, Length=244, Percent_Identity=27.0491803278689, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI87081733, Length=296, Percent_Identity=27.027027027027, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790522, Length=257, Percent_Identity=28.4046692607004, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87082230, Length=251, Percent_Identity=30.6772908366534, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787363, Length=259, Percent_Identity=24.7104247104247, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082127, Length=172, Percent_Identity=30.8139534883721, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786891, Length=258, Percent_Identity=23.2558139534884, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 50481; Mature: 50481

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS ; PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDGMPLSIGIDIGGTNLRAARISGTGEIIKRVSEKSAPDPELVLGRIADMVRLLDTPDV
CCCCCEEEEEEEECCCCEEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
KAIGVGVPGRVDARRGAVLSGGYVNLASVALAQRLEDMTGKPVIIDNDCNMALAAEMALG
EEEECCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHC
AGRGHGNIVMFTIGTGIGGAVAQDRRITRGSATAGQLGHITVDVNGEVCACGRRGCVETT
CCCCCCCEEEEEECCCCCCHHHCCCCCCCCCCCCCCCEEEEEEECCCEEECCCCCCCCCC
SSGTALGRHIARAGLGTDISVDQLFARDAAGDIQARGVLDAWAKPLRAAIDTAVAMLAPD
CCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHCCC
LVLLGGGLGRAAHAALGRAPALAPWYQCQVEAAQLGDDAGVIGAGLQALAAEPHLSPSTQ
CEEECCCCCHHHHHHHCCCCCCCCHHHEEEEHHHCCCCCCHHHHHHHHHHCCCCCCCCCC
SSRPLRAVLVNGIPASGKSTVSRGIADRMDWPLLALDTIKNPFLEVLGGGDRLFNRTLGR
CCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHH
ASYQAIWSVVGEAPAGTTFIVDAWFGFQPREVLEDHLRKAGVEQTFEIWCHAPGEVLAER
HHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEHEEECCCHHHHHHH
YGARLDLRPAGHPGAAYIPELIELAKRAEPLRRGPFFDVDTTKPIDFDTITAWLRATMDG
HCCEEEECCCCCCCHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCC
RA
CC
>Mature Secondary Structure
MQDGMPLSIGIDIGGTNLRAARISGTGEIIKRVSEKSAPDPELVLGRIADMVRLLDTPDV
CCCCCEEEEEEEECCCCEEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
KAIGVGVPGRVDARRGAVLSGGYVNLASVALAQRLEDMTGKPVIIDNDCNMALAAEMALG
EEEECCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHC
AGRGHGNIVMFTIGTGIGGAVAQDRRITRGSATAGQLGHITVDVNGEVCACGRRGCVETT
CCCCCCCEEEEEECCCCCCHHHCCCCCCCCCCCCCCCEEEEEEECCCEEECCCCCCCCCC
SSGTALGRHIARAGLGTDISVDQLFARDAAGDIQARGVLDAWAKPLRAAIDTAVAMLAPD
CCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHCCC
LVLLGGGLGRAAHAALGRAPALAPWYQCQVEAAQLGDDAGVIGAGLQALAAEPHLSPSTQ
CEEECCCCCHHHHHHHCCCCCCCCHHHEEEEHHHCCCCCCHHHHHHHHHHCCCCCCCCCC
SSRPLRAVLVNGIPASGKSTVSRGIADRMDWPLLALDTIKNPFLEVLGGGDRLFNRTLGR
CCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHH
ASYQAIWSVVGEAPAGTTFIVDAWFGFQPREVLEDHLRKAGVEQTFEIWCHAPGEVLAER
HHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEHEEECCCHHHHHHH
YGARLDLRPAGHPGAAYIPELIELAKRAEPLRRGPFFDVDTTKPIDFDTITAWLRATMDG
HCCEEEECCCCCCCHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCC
RA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]