Click here to switch to the map view.

The map label for this gene is appB [H]

Identifier: 13472845

GI number: 13472845

Start: 2618347

End: 2619345

Strand: Direct

Name: appB [H]

Synonym: mlr3266

Alternate gene names: 13472845

Gene position: 2618347-2619345 (Clockwise)

Preceding gene: 13472844

Following gene: 13472846

Centisome position: 37.21

GC content: 57.96

Gene sequence:

>999_bases
GTGTTTCGATATATTGTCTGGCGCATAGCCGTGATGGTTCCAACGCTGCTGATCATATCGGCGCTGGTGTTCACGATCAT
CGAACTTCCCCCGGGCGACTATTTCGACAGCTATGTCGCCGAGCTTCGGGCTCAGGGCGAGGCGGTGGATTCGGATCGCA
TCGAGATGATGCGCAAGGAATATGGTTTCGACAAGCCGCCGATCATTCGCTACTTCTACTGGGTCGGCGGGATGCTGCAC
GGCGATTTCGGCTATTCCTTCGAATATCAGCTGCCGGTTCGCGACGTCGTCGGGGACCGAATGTGGCTGACCGTGCTGGT
TTCCTTCGTCACGATCATCTTCACCTGGCTCATCGCCTTTCCGATCGGCATGTACTCCGCCACGCATCAATACAGCTGGG
GCGACTACGGCCTGACTTTCTTCGGCCTTCTCGGCCTTGCCATTCCGAACTTCATGCTGGCGCTGATCCTGATGTATTTC
GCCAATATCTGGTTCGGCACGTCCATCGGCCATCTCATGGACCCGCAATATCTCGGCGAGCCGATGAGCTGGGCCAAGGC
AAAGTCGATCCTCGCCCATCTCTGGATCCCGGTCTTGATCATCGGCGCCGGAGGGACGGCAAGCATGATCCGGCGGCTGC
GCGCCAATCTGCTCGATGAGCTACACAAGCAATACGTCGTGACCGCGCGCGCCAAAGGCCTTCATCCCTTCAAGACGCTG
GTCAAATATCCGCTGCGCATGGCGCTCAATTTCTTCATTTCCGACATCGGCTCCATCCTGCCGGCCATCATCTCCGGCGC
CGAAATCACGGCGATCGTGCTGTCTTTGGAAACGACCGGGCCGATGCTGATCAGGGCACTGCAAAGCCAGGACATGTATC
TGGCAGGGTCGTTCCTAATGTTCCTCGCCTTCCTGACGGTCATCGGTGTCCTGATCTCCGACCTGGCGCTGGCGCTGCTT
GATCCACGAATTCGTTTGCAGGGCGGCAGCACCAAATGA

Upstream 100 bases:

>100_bases
GACTGCGCAATCTGCCTGACAAGGCGCTCTACGGCTACGACCCGACCGCCTATTTCGGTGTCTACATGCCGGATACATTC
TGGCTTGGAGAGACCTGAGC

Downstream 100 bases:

>100_bases
ACACGCCTTCGCCGCTGCCCGCTCCGGGTGCTCCACTGCAACACTACGTTTCCATCGCGCCCTTTGACCTGCAGTCGGTC
GAGGCGATGACGCCGGAGCA

Product: oligopeptide ABC transporter, permease protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MFRYIVWRIAVMVPTLLIISALVFTIIELPPGDYFDSYVAELRAQGEAVDSDRIEMMRKEYGFDKPPIIRYFYWVGGMLH
GDFGYSFEYQLPVRDVVGDRMWLTVLVSFVTIIFTWLIAFPIGMYSATHQYSWGDYGLTFFGLLGLAIPNFMLALILMYF
ANIWFGTSIGHLMDPQYLGEPMSWAKAKSILAHLWIPVLIIGAGGTASMIRRLRANLLDELHKQYVVTARAKGLHPFKTL
VKYPLRMALNFFISDIGSILPAIISGAEITAIVLSLETTGPMLIRALQSQDMYLAGSFLMFLAFLTVIGVLISDLALALL
DPRIRLQGGSTK

Sequences:

>Translated_332_residues
MFRYIVWRIAVMVPTLLIISALVFTIIELPPGDYFDSYVAELRAQGEAVDSDRIEMMRKEYGFDKPPIIRYFYWVGGMLH
GDFGYSFEYQLPVRDVVGDRMWLTVLVSFVTIIFTWLIAFPIGMYSATHQYSWGDYGLTFFGLLGLAIPNFMLALILMYF
ANIWFGTSIGHLMDPQYLGEPMSWAKAKSILAHLWIPVLIIGAGGTASMIRRLRANLLDELHKQYVVTARAKGLHPFKTL
VKYPLRMALNFFISDIGSILPAIISGAEITAIVLSLETTGPMLIRALQSQDMYLAGSFLMFLAFLTVIGVLISDLALALL
DPRIRLQGGSTK
>Mature_332_residues
MFRYIVWRIAVMVPTLLIISALVFTIIELPPGDYFDSYVAELRAQGEAVDSDRIEMMRKEYGFDKPPIIRYFYWVGGMLH
GDFGYSFEYQLPVRDVVGDRMWLTVLVSFVTIIFTWLIAFPIGMYSATHQYSWGDYGLTFFGLLGLAIPNFMLALILMYF
ANIWFGTSIGHLMDPQYLGEPMSWAKAKSILAHLWIPVLIIGAGGTASMIRRLRANLLDELHKQYVVTARAKGLHPFKTL
VKYPLRMALNFFISDIGSILPAIISGAEITAIVLSLETTGPMLIRALQSQDMYLAGSFLMFLAFLTVIGVLISDLALALL
DPRIRLQGGSTK

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=341, Percent_Identity=26.099706744868, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1789888, Length=330, Percent_Identity=27.5757575757576, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1787053, Length=327, Percent_Identity=26.2996941896024, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788504, Length=368, Percent_Identity=27.445652173913, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787497, Length=328, Percent_Identity=25.3048780487805, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1787761, Length=344, Percent_Identity=26.453488372093, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787550, Length=268, Percent_Identity=26.1194029850746, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37378; Mature: 37378

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRYIVWRIAVMVPTLLIISALVFTIIELPPGDYFDSYVAELRAQGEAVDSDRIEMMRKE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
YGFDKPPIIRYFYWVGGMLHGDFGYSFEYQLPVRDVVGDRMWLTVLVSFVTIIFTWLIAF
CCCCCCHHHHHHHHHCCCEECCCCCCEEEECCHHHHHCCHHHHHHHHHHHHHHHHHHHHH
PIGMYSATHQYSWGDYGLTFFGLLGLAIPNFMLALILMYFANIWFGTSIGHLMDPQYLGE
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHCCC
PMSWAKAKSILAHLWIPVLIIGAGGTASMIRRLRANLLDELHKQYVVTARAKGLHPFKTL
CHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
VKYPLRMALNFFISDIGSILPAIISGAEITAIVLSLETTGPMLIRALQSQDMYLAGSFLM
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEEECCCCHHHHHHHHCCCHHHHHHHHH
FLAFLTVIGVLISDLALALLDPRIRLQGGSTK
HHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC
>Mature Secondary Structure
MFRYIVWRIAVMVPTLLIISALVFTIIELPPGDYFDSYVAELRAQGEAVDSDRIEMMRKE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
YGFDKPPIIRYFYWVGGMLHGDFGYSFEYQLPVRDVVGDRMWLTVLVSFVTIIFTWLIAF
CCCCCCHHHHHHHHHCCCEECCCCCCEEEECCHHHHHCCHHHHHHHHHHHHHHHHHHHHH
PIGMYSATHQYSWGDYGLTFFGLLGLAIPNFMLALILMYFANIWFGTSIGHLMDPQYLGE
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHCCC
PMSWAKAKSILAHLWIPVLIIGAGGTASMIRRLRANLLDELHKQYVVTARAKGLHPFKTL
CHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
VKYPLRMALNFFISDIGSILPAIISGAEITAIVLSLETTGPMLIRALQSQDMYLAGSFLM
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEEECCCCHHHHHHHHCCCHHHHHHHHH
FLAFLTVIGVLISDLALALLDPRIRLQGGSTK
HHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]