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The map label for this gene is appC [H]

Identifier: 13472846

GI number: 13472846

Start: 2619432

End: 2620523

Strand: Direct

Name: appC [H]

Synonym: mlr3267

Alternate gene names: 13472846

Gene position: 2619432-2620523 (Clockwise)

Preceding gene: 13472845

Following gene: 13472847

Centisome position: 37.23

GC content: 59.62

Gene sequence:

>1092_bases
ATGACGCCGGAGCAATCGAAGGTCTTCCAGGCGTCGCAGTTGCGGCTGATGTGGTGGAAATTCCGAAGGCACCGGCTTGC
CGTGGTATCCGGCATATTCCTGGCAGCGCTTTATTTCGGGATACTGATCTGCGAGTTCCTAGCGCCCTACAATCTGCACA
CGCGCAACATGGACTACATCTATTCGCCGCCGCAGCGGGTGCGCCTGTTCCACAACGGCCAGTTCGTCGGGCCGTTCGTC
TATGGCCGCCAGATGACGCTGGATATGGACACGCTCAAGCGGAACTACATCGAGAATCAGGATGATGTTCAGCGGATTCG
TTTCTTCTGCAAGGGCGACACTTACCGGTTCTGGGGGCTTATCGAAGGTAACAGGCATCTTTTCTGCCCTGCCGAAAACG
GCCAGCTCTTTCTGGCCGGCACTGACAGGCTGGGGCGCGATGTGCTCTCGCGCATCATCTTTGGCGCACGCATTTCACTG
ACAATCGGCCTCGTCGGCATCAGTTTCAGCTTCCTGCTCGGCATTGTCATCGGCGGACTGGCCGGCTATCACGGCGGTAT
CTTCGACCTGATCGTTCAACGAATAATCGAAGTTCTGCAATCGATCCCCAGCATTCCGCTATGGCTGGCTCTGGCGGCGA
TCATGCCGATAACCTGGAGTCCGATCCTGATCTATTTCGGCATCACCGTCATCCTCGGGCTGCTCCACTGGACCGGACTG
GCGCGGGCCGTGCGTTCAAAGCTTCTAGCTTTGCGCGAGGAGGATTACGTTCTGGCCGCGCAATTGATGGGCGCCAGCAG
CAGCCGCATCATCGGGCGGCACCTCATTCCCGGCTTCATGTCGCATCTGATCGCGACCGCGACGATCGCCATACCCGGCA
TGATCCTGGGCGAGACGGCGCTGAGCTTCCTCGGGCTCGGCCTGAGGGCGCCGACAACCAGCTGGGGCATCCTGCTCACC
GAGGCACGCAGCGTCAGCGTCATCGCTTTCTATCCATGGCTGCTTCTGCCGATGCTCCCCGTCATTCTCGTCATCATGGC
GTTCAACTTCCTCGGCGACGGCTTGCGGGACGCCGCAGACCCCTACAAGTGA

Upstream 100 bases:

>100_bases
GCAGCACCAAATGAACACGCCTTCGCCGCTGCCCGCTCCGGGTGCTCCACTGCAACACTACGTTTCCATCGCGCCCTTTG
ACCTGCAGTCGGTCGAGGCG

Downstream 100 bases:

>100_bases
CTTCGCTATGCCGCCGCGCGCCGGGCCGCCGACTCCACCCGGTATGACCCTTGTCGGCAGCCTGTTCGGTTATTGCGGTG
TTCATCGTTCGCCTCTATAT

Product: oligopeptide ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MTPEQSKVFQASQLRLMWWKFRRHRLAVVSGIFLAALYFGILICEFLAPYNLHTRNMDYIYSPPQRVRLFHNGQFVGPFV
YGRQMTLDMDTLKRNYIENQDDVQRIRFFCKGDTYRFWGLIEGNRHLFCPAENGQLFLAGTDRLGRDVLSRIIFGARISL
TIGLVGISFSFLLGIVIGGLAGYHGGIFDLIVQRIIEVLQSIPSIPLWLALAAIMPITWSPILIYFGITVILGLLHWTGL
ARAVRSKLLALREEDYVLAAQLMGASSSRIIGRHLIPGFMSHLIATATIAIPGMILGETALSFLGLGLRAPTTSWGILLT
EARSVSVIAFYPWLLLPMLPVILVIMAFNFLGDGLRDAADPYK

Sequences:

>Translated_363_residues
MTPEQSKVFQASQLRLMWWKFRRHRLAVVSGIFLAALYFGILICEFLAPYNLHTRNMDYIYSPPQRVRLFHNGQFVGPFV
YGRQMTLDMDTLKRNYIENQDDVQRIRFFCKGDTYRFWGLIEGNRHLFCPAENGQLFLAGTDRLGRDVLSRIIFGARISL
TIGLVGISFSFLLGIVIGGLAGYHGGIFDLIVQRIIEVLQSIPSIPLWLALAAIMPITWSPILIYFGITVILGLLHWTGL
ARAVRSKLLALREEDYVLAAQLMGASSSRIIGRHLIPGFMSHLIATATIAIPGMILGETALSFLGLGLRAPTTSWGILLT
EARSVSVIAFYPWLLLPMLPVILVIMAFNFLGDGLRDAADPYK
>Mature_362_residues
TPEQSKVFQASQLRLMWWKFRRHRLAVVSGIFLAALYFGILICEFLAPYNLHTRNMDYIYSPPQRVRLFHNGQFVGPFVY
GRQMTLDMDTLKRNYIENQDDVQRIRFFCKGDTYRFWGLIEGNRHLFCPAENGQLFLAGTDRLGRDVLSRIIFGARISLT
IGLVGISFSFLLGIVIGGLAGYHGGIFDLIVQRIIEVLQSIPSIPLWLALAAIMPITWSPILIYFGITVILGLLHWTGLA
RAVRSKLLALREEDYVLAAQLMGASSSRIIGRHLIPGFMSHLIATATIAIPGMILGETALSFLGLGLRAPTTSWGILLTE
ARSVSVIAFYPWLLLPMLPVILVIMAFNFLGDGLRDAADPYK

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=222, Percent_Identity=38.7387387387387, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787498, Length=234, Percent_Identity=40.1709401709402, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789889, Length=228, Percent_Identity=34.6491228070175, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1787760, Length=222, Percent_Identity=33.7837837837838, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788505, Length=364, Percent_Identity=30.7692307692308, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789964, Length=237, Percent_Identity=36.2869198312236, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787549, Length=223, Percent_Identity=34.5291479820628, Blast_Score=98, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 40720; Mature: 40589

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPEQSKVFQASQLRLMWWKFRRHRLAVVSGIFLAALYFGILICEFLAPYNLHTRNMDYI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
YSPPQRVRLFHNGQFVGPFVYGRQMTLDMDTLKRNYIENQDDVQRIRFFCKGDTYRFWGL
ECCHHHEEEEECCEEECHHHCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEE
IEGNRHLFCPAENGQLFLAGTDRLGRDVLSRIIFGARISLTIGLVGISFSFLLGIVIGGL
EECCEEEEEECCCCEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AGYHGGIFDLIVQRIIEVLQSIPSIPLWLALAAIMPITWSPILIYFGITVILGLLHWTGL
HHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ARAVRSKLLALREEDYVLAAQLMGASSSRIIGRHLIPGFMSHLIATATIAIPGMILGETA
HHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LSFLGLGLRAPTTSWGILLTEARSVSVIAFYPWLLLPMLPVILVIMAFNFLGDGLRDAAD
HHHHHCCCCCCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCC
PYK
CCC
>Mature Secondary Structure 
TPEQSKVFQASQLRLMWWKFRRHRLAVVSGIFLAALYFGILICEFLAPYNLHTRNMDYI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
YSPPQRVRLFHNGQFVGPFVYGRQMTLDMDTLKRNYIENQDDVQRIRFFCKGDTYRFWGL
ECCHHHEEEEECCEEECHHHCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEE
IEGNRHLFCPAENGQLFLAGTDRLGRDVLSRIIFGARISLTIGLVGISFSFLLGIVIGGL
EECCEEEEEECCCCEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AGYHGGIFDLIVQRIIEVLQSIPSIPLWLALAAIMPITWSPILIYFGITVILGLLHWTGL
HHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ARAVRSKLLALREEDYVLAAQLMGASSSRIIGRHLIPGFMSHLIATATIAIPGMILGETA
HHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LSFLGLGLRAPTTSWGILLTEARSVSVIAFYPWLLLPMLPVILVIMAFNFLGDGLRDAAD
HHHHHCCCCCCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCC
PYK
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]