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The map label for this gene is rlmL [H]

Identifier: 13472800

GI number: 13472800

Start: 2565994

End: 2567010

Strand: Direct

Name: rlmL [H]

Synonym: mlr3209

Alternate gene names: 13472800

Gene position: 2565994-2567010 (Clockwise)

Preceding gene: 13472795

Following gene: 13472801

Centisome position: 36.47

GC content: 66.67

Gene sequence:

>1017_bases
GTGCGTCCGCACGAGACGCGTGGGCGGCCGGACGCCAGGCCGCGCGAGGCGCGTGACGCGAAACCGGACAGCCAGCCCGC
ACCGAATTCAGCCCCGCGCATCCTTGCCCGCCGTGACGGCGCCCTGCCCGCCGAGCAGCTTCCGCTGATCCTCGAAGTCG
CGCCCAACGCCGACTATGCGCTGCTGGACAGCGGCGCCGGCCAGAAGCTCGAACAATACGGCCCCTACCGCATCGTGCGG
CCCGAGGGCCAGGCGATCTGGCAGAAAGCCTTGCCGGCGAAGGACTGGGAGCGTGCCGATGCCATCTTCACCGGCGACAC
CGACGAGGAAGGCATCGGCCGCTGGCGGTTCCCGAAGATGCCGCTCGGCGAGACCTGGCCGATGAAGCATGACGGCATCG
ATTATCTCGGCCGTTTCACCTCGTTTCGCCATGTCGGCGTCTTCCCCGAACAGGCCTCGCACTGGGACCACATGGCCGGG
CTGATCGCGGCCGCCAAACGGCCGGTCAAAGTATTGAATCTGTTCGGCTATACCGGGCTCGCCTCGCTGGTGGCGGCCCG
CGCAGGCGCAGAGGTCACCCATGTCGATGCCTCGAAGAAGGCGATCGGCTGGGCCCGCGAGAACCAGGAAATGGCCGGGC
TCGGCGGCAAGCCGATCCGCTGGATCGTCGACGATGCGGTGAAATTCGCCGAGCGCGAGGAGCGCCGCGGCAGCCGCTAC
GACATCATCCTGTTCGACCCGCCGGCCTATGGCCGCGGCCCCAAGGGCGAGGTCTGGCAATTGTTCGAGGATTTGCCTGC
CCTGACCGATCTATGCCGGACGATCCTGACGCCGAAACCGCTTGCCGTGGTGTTGACCGCATATTCGATCCGCGCCTCCT
TCTTCGCTATCCACGCTTTGATGCGCGACACCTTCGCCGGCATGGGCGGCAGGGTTGAATCGGGCGAGCTGATCATCCGC
GAAAAGTCCGCCGGCAGGGCGCTTTCGACCTCATTGTTTTCGCGTTGGGTGGCCTGA

Upstream 100 bases:

>100_bases
ATGCCAAAAGCGGCACGCCGCTCGGAGATGCTCCCGCTTGAAGTCTTTTCGCGACAAACGCCGCGACAACCGCCCCACCG
CGAAAAGCGGAACCGGAGAG

Downstream 100 bases:

>100_bases
ATGAACGAACGGCATGTCGGCGCACCCGGCCAGGTGAAGGAAGTCACCAGCCTCGCCAATCCACTGATCAAGGACATCAA
GGCGCTTGCCCTGAAGAAAT

Product: SAM dependent methyltransferase

Products: NA

Alternate protein names: 23S rRNA m2G2445 methyltransferase; rRNA (guanine-N(2)-)-methyltransferase rlmL [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MRPHETRGRPDARPREARDAKPDSQPAPNSAPRILARRDGALPAEQLPLILEVAPNADYALLDSGAGQKLEQYGPYRIVR
PEGQAIWQKALPAKDWERADAIFTGDTDEEGIGRWRFPKMPLGETWPMKHDGIDYLGRFTSFRHVGVFPEQASHWDHMAG
LIAAAKRPVKVLNLFGYTGLASLVAARAGAEVTHVDASKKAIGWARENQEMAGLGGKPIRWIVDDAVKFAEREERRGSRY
DIILFDPPAYGRGPKGEVWQLFEDLPALTDLCRTILTPKPLAVVLTAYSIRASFFAIHALMRDTFAGMGGRVESGELIIR
EKSAGRALSTSLFSRWVA

Sequences:

>Translated_338_residues
MRPHETRGRPDARPREARDAKPDSQPAPNSAPRILARRDGALPAEQLPLILEVAPNADYALLDSGAGQKLEQYGPYRIVR
PEGQAIWQKALPAKDWERADAIFTGDTDEEGIGRWRFPKMPLGETWPMKHDGIDYLGRFTSFRHVGVFPEQASHWDHMAG
LIAAAKRPVKVLNLFGYTGLASLVAARAGAEVTHVDASKKAIGWARENQEMAGLGGKPIRWIVDDAVKFAEREERRGSRY
DIILFDPPAYGRGPKGEVWQLFEDLPALTDLCRTILTPKPLAVVLTAYSIRASFFAIHALMRDTFAGMGGRVESGELIIR
EKSAGRALSTSLFSRWVA
>Mature_338_residues
MRPHETRGRPDARPREARDAKPDSQPAPNSAPRILARRDGALPAEQLPLILEVAPNADYALLDSGAGQKLEQYGPYRIVR
PEGQAIWQKALPAKDWERADAIFTGDTDEEGIGRWRFPKMPLGETWPMKHDGIDYLGRFTSFRHVGVFPEQASHWDHMAG
LIAAAKRPVKVLNLFGYTGLASLVAARAGAEVTHVDASKKAIGWARENQEMAGLGGKPIRWIVDDAVKFAEREERRGSRY
DIILFDPPAYGRGPKGEVWQLFEDLPALTDLCRTILTPKPLAVVLTAYSIRASFFAIHALMRDTFAGMGGRVESGELIIR
EKSAGRALSTSLFSRWVA

Specific function: Specifically methylates the guanosine in position 2445 (m2G2445) of 23S rRNA [H]

COG id: COG1092

COG function: function code R; Predicted SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 THUMP domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR000241
- InterPro:   IPR017244
- InterPro:   IPR019614
- InterPro:   IPR004114 [H]

Pfam domain/function: PF10672 Methyltrans_SAM; PF02926 THUMP; PF01170 UPF0020 [H]

EC number: =2.1.1.173 [H]

Molecular weight: Translated: 37474; Mature: 37474

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPHETRGRPDARPREARDAKPDSQPAPNSAPRILARRDGALPAEQLPLILEVAPNADYA
CCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCHHHHHCCCCCCHHHCCEEEEECCCCCEE
LLDSGAGQKLEQYGPYRIVRPEGQAIWQKALPAKDWERADAIFTGDTDEEGIGRWRFPKM
EEECCCCCHHHHCCCEEEECCCCHHHHHHCCCCCCHHHCCEEEECCCCCCCCCCCCCCCC
PLGETWPMKHDGIDYLGRFTSFRHVGVFPEQASHWDHMAGLIAAAKRPVKVLNLFGYTGL
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ASLVAARAGAEVTHVDASKKAIGWARENQEMAGLGGKPIRWIVDDAVKFAEREERRGSRY
HHHHHHHCCCCEEEECCCHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCE
DIILFDPPAYGRGPKGEVWQLFEDLPALTDLCRTILTPKPLAVVLTAYSIRASFFAIHAL
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
MRDTFAGMGGRVESGELIIREKSAGRALSTSLFSRWVA
HHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MRPHETRGRPDARPREARDAKPDSQPAPNSAPRILARRDGALPAEQLPLILEVAPNADYA
CCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCHHHHHCCCCCCHHHCCEEEEECCCCCEE
LLDSGAGQKLEQYGPYRIVRPEGQAIWQKALPAKDWERADAIFTGDTDEEGIGRWRFPKM
EEECCCCCHHHHCCCEEEECCCCHHHHHHCCCCCCHHHCCEEEECCCCCCCCCCCCCCCC
PLGETWPMKHDGIDYLGRFTSFRHVGVFPEQASHWDHMAGLIAAAKRPVKVLNLFGYTGL
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ASLVAARAGAEVTHVDASKKAIGWARENQEMAGLGGKPIRWIVDDAVKFAEREERRGSRY
HHHHHHHCCCCEEEECCCHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCE
DIILFDPPAYGRGPKGEVWQLFEDLPALTDLCRTILTPKPLAVVLTAYSIRASFFAIHAL
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
MRDTFAGMGGRVESGELIIREKSAGRALSTSLFSRWVA
HHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA