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The map label for this gene is rbsK [H]

Identifier: 13472780

GI number: 13472780

Start: 2550582

End: 2551502

Strand: Direct

Name: rbsK [H]

Synonym: mlr3185

Alternate gene names: 13472780

Gene position: 2550582-2551502 (Clockwise)

Preceding gene: 13472779

Following gene: 13472781

Centisome position: 36.25

GC content: 67.97

Gene sequence:

>921_bases
TTGATAGTCGTCGTCGGCTCGATCAATCTCGACCTTATCGCCAAAGTCGACCGCTTGCCGAGCCCCGGCGAAACGGTGAG
GGGTTCCGGTTTCTCCACGGCGCCCGGCGGCAAGGGCGCCAACCAGGCGCTGGCCGCCGCGCGCGCCGGTGTCCCGGTGC
GCATGGTCGGCGCCGTCGGCAAGGACAGTTTCGCCGGCGAGGCGCTGGCATTGCTGCGCGAGGCCAAGGTCGACCTGTCG
GGCGTGGCGGAAACCTTTGCCTCGACCGGAACGGCACTGATCATGGTCGGTGACGACGGCGAGAACATCATCGCCGTGGT
TTCCGGCGCCAATGCGTCCGTGGTGACCGGCGACCTCTCCAAGGCCTTCCTGAAAAAGGGCGACGTCGTGCTGCTTCAGC
ACGAGATCCCGCTGGCGACCGTCGATGCGGCACTCGACCAGGCACGCGCGGCCGGCGCCATCACCGTGCTCAACACCGCT
CCTTTCCAGGGCGACGCGACGGCTTTCCTCGGCAAGGCCGATTATGTCGTCGCCAACGAGACCGAGTTCGACCTCTATGG
CGAGGCGCTGGCGCTGAACGGCCGCGACCGTGCGGCACGCATGCGCGACTTCGCCGCGAAAACCGGCCGCAGCATCGTCG
TCACCCTCGGCGGCGACGGCGTCATGGCGGCGACGCCGAGCGATTTCCTGACCGTTGCGGCCATGAAGATCACGCCTGTC
GACACGGTCGGCGCCGGCGACACCTTCTGCGGCTACTTCGCTGCCGGCCTGTCGTCCGGCCTTGCGCTCGACCAAGCGCT
GGCGCGCGCCGGTGCGGCAGGCTCGCTCGCATGCCTGAAGCCTGGCGCCCAGCCGGCGATCCCGCTGGCCAAGGATGTCG
ATCAAGCCTTGCAGGAAGTCAGCAGAAATGATGCGCCCTGA

Upstream 100 bases:

>100_bases
GCATTCATATTGATGCACCAGCTCCGCCATCTTCGATCCACATCGTGCTTTCCGAAAGTCGATCCTGATTTCCGGCCAGC
GCTGGCAGGGAGGTACTTTC

Downstream 100 bases:

>100_bases
GACCAAGCATGCCGTGCCGCGGGCCGGCGATGTCTGCCGCCTGTCCGCCGTCGAGCTGGCCGGCGCCATTCGCCGCAAGA
AACTGTCCGTGCGCGAGGTG

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MIVVVGSINLDLIAKVDRLPSPGETVRGSGFSTAPGGKGANQALAAARAGVPVRMVGAVGKDSFAGEALALLREAKVDLS
GVAETFASTGTALIMVGDDGENIIAVVSGANASVVTGDLSKAFLKKGDVVLLQHEIPLATVDAALDQARAAGAITVLNTA
PFQGDATAFLGKADYVVANETEFDLYGEALALNGRDRAARMRDFAAKTGRSIVVTLGGDGVMAATPSDFLTVAAMKITPV
DTVGAGDTFCGYFAAGLSSGLALDQALARAGAAGSLACLKPGAQPAIPLAKDVDQALQEVSRNDAP

Sequences:

>Translated_306_residues
MIVVVGSINLDLIAKVDRLPSPGETVRGSGFSTAPGGKGANQALAAARAGVPVRMVGAVGKDSFAGEALALLREAKVDLS
GVAETFASTGTALIMVGDDGENIIAVVSGANASVVTGDLSKAFLKKGDVVLLQHEIPLATVDAALDQARAAGAITVLNTA
PFQGDATAFLGKADYVVANETEFDLYGEALALNGRDRAARMRDFAAKTGRSIVVTLGGDGVMAATPSDFLTVAAMKITPV
DTVGAGDTFCGYFAAGLSSGLALDQALARAGAAGSLACLKPGAQPAIPLAKDVDQALQEVSRNDAP
>Mature_306_residues
MIVVVGSINLDLIAKVDRLPSPGETVRGSGFSTAPGGKGANQALAAARAGVPVRMVGAVGKDSFAGEALALLREAKVDLS
GVAETFASTGTALIMVGDDGENIIAVVSGANASVVTGDLSKAFLKKGDVVLLQHEIPLATVDAALDQARAAGAITVLNTA
PFQGDATAFLGKADYVVANETEFDLYGEALALNGRDRAARMRDFAAKTGRSIVVTLGGDGVMAATPSDFLTVAAMKITPV
DTVGAGDTFCGYFAAGLSSGLALDQALARAGAAGSLACLKPGAQPAIPLAKDVDQALQEVSRNDAP

Specific function: Ribose metabolism; first step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=34.1216216216216, Blast_Score=141, Evalue=7e-34,
Organism=Escherichia coli, GI1790193, Length=296, Percent_Identity=34.7972972972973, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1789775, Length=251, Percent_Identity=25.8964143426295, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082343, Length=298, Percent_Identity=27.5167785234899, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=306, Percent_Identity=35.9477124183007, Blast_Score=144, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6319884, Length=330, Percent_Identity=33.3333333333333, Blast_Score=132, Evalue=5e-32,
Organism=Drosophila melanogaster, GI20128807, Length=302, Percent_Identity=34.4370860927152, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24583886, Length=300, Percent_Identity=29.3333333333333, Blast_Score=108, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 30742; Mature: 30742

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVVVGSINLDLIAKVDRLPSPGETVRGSGFSTAPGGKGANQALAAARAGVPVRMVGAVG
CEEEEECCCEEEHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCC
KDSFAGEALALLREAKVDLSGVAETFASTGTALIMVGDDGENIIAVVSGANASVVTGDLS
CCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCEEEECHHH
KAFLKKGDVVLLQHEIPLATVDAALDQARAAGAITVLNTAPFQGDATAFLGKADYVVANE
HHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEECCCCEEEECC
TEFDLYGEALALNGRDRAARMRDFAAKTGRSIVVTLGGDGVMAATPSDFLTVAAMKITPV
CCCEECCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCCEEEEEEEECCC
DTVGAGDTFCGYFAAGLSSGLALDQALARAGAAGSLACLKPGAQPAIPLAKDVDQALQEV
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHH
SRNDAP
HHCCCC
>Mature Secondary Structure
MIVVVGSINLDLIAKVDRLPSPGETVRGSGFSTAPGGKGANQALAAARAGVPVRMVGAVG
CEEEEECCCEEEHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCC
KDSFAGEALALLREAKVDLSGVAETFASTGTALIMVGDDGENIIAVVSGANASVVTGDLS
CCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCEEEECHHH
KAFLKKGDVVLLQHEIPLATVDAALDQARAAGAITVLNTAPFQGDATAFLGKADYVVANE
HHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEECCCCEEEECC
TEFDLYGEALALNGRDRAARMRDFAAKTGRSIVVTLGGDGVMAATPSDFLTVAAMKITPV
CCCEECCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCCEEEEEEEECCC
DTVGAGDTFCGYFAAGLSSGLALDQALARAGAAGSLACLKPGAQPAIPLAKDVDQALQEV
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHH
SRNDAP
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]