BacMap

Definition	Mesorhizobium loti MAFF303099 chromosome, complete genome.
Accession	NC_002678
Length	7,036,071

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The map label for this gene is fabG [H]

Identifier: 13472685

GI number: 13472685

Start: 2461993

End: 2462754

Strand: Direct

Name: fabG [H]

Synonym: mlr3057

Alternate gene names: 13472685

Gene position: 2461993-2462754 (Clockwise)

Preceding gene: 13472684

Following gene: 13472686

Centisome position: 34.99

GC content: 65.75

Gene sequence:

>762_bases
ATGACCCGCCCCGCAGCCATCGTCACCGGCGGCGCACGCGGCATCGGGCTGGCTTGCGCGGAAGCGCTGGCCGATGCCGG
CTTCGACATTCTGGTTGCCGACCTTGCCGAACAGGCGCCTGACGGGCTCGACACAGACATCTCGGCTCGCGGTGCGAAAC
TCGCCTATGTCAGTTGTGACGTCGCCAATCTCGACAGCCACGCCGTGTTGATCGATGCCGCGATGCGCGTCTTCGGCCGC
ATCGACTGTCTCGTCAACAACGCCGGCGTCGGCGCCGTGGTGCGCGGCGACCTGCTGGAACTGAAGCCGGAAAATTTCGA
CCGCACGCTGGGCATCAACCTGCGCGGCACGGTCTTCCTCAGCCAGGCCGTCGCCAAGGCGATGCTGGCCACACTGGGCG
ATCACACAAGATCGATCATCACCGTCACCTCCGTCAGCGCCGAAATGGCCTCGCCGGAGCGCTCCGAATACTGCGTGTCG
AAGGCCGGGCTTTCCATGTGGGTGAAGAACCTGGCGCTGCGGCTCGCTCCGGAAAACATCGGCGTGTTCGAGGTGCGGCC
AGGCATTATCCGCACCGACATGACCGCAGGCGTCACCGCCAAATATGATGCCTTGATCGAAGGCGGGCTGGTGCCGGCCA
AGCGCTGGGGCGAAGCGTCAGACATCGGCGCGATGGTGGCGACGCTTGCCGCCGGCAGGCTCGGCTTTTCGACCGGCTCG
ATCATCAATGTCGACGGCGCGCTCTCCGTGCCGCGGCTGTAG

Upstream 100 bases:

>100_bases
ATGCCAGCTTTTTGCCGAACTCGGCTGCGGTCAACCCTGCCCTGTCGATCGCCGCTCAAGCGCTTCGGGTTGCGGACCAT
ATTCGCAAGGCTGGCTTCCA

Downstream 100 bases:

>100_bases
GTGGAAACGACATGACCGACTACATCATCGTGGGCGCCGGCCCGGCCGGCTGTGTTCTGGCCAACCGGCTGAGCGAGGAC
CCCGGCAATTCCGTGCTGCT

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MTRPAAIVTGGARGIGLACAEALADAGFDILVADLAEQAPDGLDTDISARGAKLAYVSCDVANLDSHAVLIDAAMRVFGR
IDCLVNNAGVGAVVRGDLLELKPENFDRTLGINLRGTVFLSQAVAKAMLATLGDHTRSIITVTSVSAEMASPERSEYCVS
KAGLSMWVKNLALRLAPENIGVFEVRPGIIRTDMTAGVTAKYDALIEGGLVPAKRWGEASDIGAMVATLAAGRLGFSTGS
IINVDGALSVPRL

Sequences:

>Translated_253_residues
MTRPAAIVTGGARGIGLACAEALADAGFDILVADLAEQAPDGLDTDISARGAKLAYVSCDVANLDSHAVLIDAAMRVFGR
IDCLVNNAGVGAVVRGDLLELKPENFDRTLGINLRGTVFLSQAVAKAMLATLGDHTRSIITVTSVSAEMASPERSEYCVS
KAGLSMWVKNLALRLAPENIGVFEVRPGIIRTDMTAGVTAKYDALIEGGLVPAKRWGEASDIGAMVATLAAGRLGFSTGS
IINVDGALSVPRL
>Mature_252_residues
TRPAAIVTGGARGIGLACAEALADAGFDILVADLAEQAPDGLDTDISARGAKLAYVSCDVANLDSHAVLIDAAMRVFGRI
DCLVNNAGVGAVVRGDLLELKPENFDRTLGINLRGTVFLSQAVAKAMLATLGDHTRSIITVTSVSAEMASPERSEYCVSK
AGLSMWVKNLALRLAPENIGVFEVRPGIIRTDMTAGVTAKYDALIEGGLVPAKRWGEASDIGAMVATLAAGRLGFSTGSI
INVDGALSVPRL

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=244, Percent_Identity=30.7377049180328, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI7705925, Length=243, Percent_Identity=28.3950617283951, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=27.6264591439689, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=29.7959183673469, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=30.8641975308642, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=32.4175824175824, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=31.9371727748691, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI15277342, Length=252, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=29.3650793650794, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI4758504, Length=252, Percent_Identity=28.1746031746032, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI59889578, Length=230, Percent_Identity=27.8260869565217, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI20149619, Length=197, Percent_Identity=27.9187817258883, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI31542939, Length=193, Percent_Identity=30.5699481865285, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=35.655737704918, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=31.8181818181818, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=30.327868852459, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=28.8461538461538, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1790717, Length=251, Percent_Identity=26.2948207171315, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=28.9795918367347, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=27.0161290322581, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=31.1475409836066, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789378, Length=244, Percent_Identity=28.2786885245902, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789057, Length=254, Percent_Identity=27.1653543307087, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI2367365, Length=243, Percent_Identity=29.6296296296296, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=34.2857142857143, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=29.0836653386454, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=30.2040816326531, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=26.953125, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=28.9156626506024, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17531453, Length=193, Percent_Identity=31.6062176165803, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=26.5873015873016, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=277, Percent_Identity=27.7978339350181, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=195, Percent_Identity=30.7692307692308, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=28.4090909090909, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=270, Percent_Identity=27.037037037037, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=266, Percent_Identity=27.0676691729323, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=207, Percent_Identity=27.0531400966184, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=28.8888888888889, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=205, Percent_Identity=26.3414634146341, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=257, Percent_Identity=25.2918287937743, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=28.1481481481481, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=202, Percent_Identity=27.7227722772277, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=259, Percent_Identity=25.8687258687259, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=194, Percent_Identity=28.8659793814433, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=255, Percent_Identity=26.2745098039216, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=251, Percent_Identity=28.6852589641434, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=32.2709163346614, Blast_Score=110, Evalue=8e-25,
Organism=Drosophila melanogaster, GI21357041, Length=246, Percent_Identity=31.3008130081301, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28571526, Length=246, Percent_Identity=31.3008130081301, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI17737361, Length=250, Percent_Identity=29.2, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=26.4227642276423, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=28.4, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21358495, Length=193, Percent_Identity=27.4611398963731, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=27.5303643724696, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26211; Mature: 26079

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPAAIVTGGARGIGLACAEALADAGFDILVADLAEQAPDGLDTDISARGAKLAYVSCD
CCCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEE
VANLDSHAVLIDAAMRVFGRIDCLVNNAGVGAVVRGDLLELKPENFDRTLGINLRGTVFL
CCCCCCCHHHHHHHHHHHHHHHEEEECCCCCEEEECCEEEECCCCCCEEECCCCCHHHHH
SQAVAKAMLATLGDHTRSIITVTSVSAEMASPERSEYCVSKAGLSMWVKNLALRLAPENI
HHHHHHHHHHHHCCCCCEEEEEEECHHHHCCCCHHHHHHHHHHHHHHHHHHHHEECCCCC
GVFEVRPGIIRTDMTAGVTAKYDALIEGGLVPAKRWGEASDIGAMVATLAAGRLGFSTGS
CEEEECCCEEEECCCCCCCCHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCCC
IINVDGALSVPRL
EEEECCCCCCCCC
>Mature Secondary Structure 
TRPAAIVTGGARGIGLACAEALADAGFDILVADLAEQAPDGLDTDISARGAKLAYVSCD
CCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEE
VANLDSHAVLIDAAMRVFGRIDCLVNNAGVGAVVRGDLLELKPENFDRTLGINLRGTVFL
CCCCCCCHHHHHHHHHHHHHHHEEEECCCCCEEEECCEEEECCCCCCEEECCCCCHHHHH
SQAVAKAMLATLGDHTRSIITVTSVSAEMASPERSEYCVSKAGLSMWVKNLALRLAPENI
HHHHHHHHHHHHCCCCCEEEEEEECHHHHCCCCHHHHHHHHHHHHHHHHHHHHEECCCCC
GVFEVRPGIIRTDMTAGVTAKYDALIEGGLVPAKRWGEASDIGAMVATLAAGRLGFSTGS
CEEEECCCEEEECCCCCCCCHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCCC
IINVDGALSVPRL
EEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]