Click here to switch to the map view.

The map label for this gene is betA [C]

Identifier: 13472686

GI number: 13472686

Start: 2462766

End: 2464394

Strand: Direct

Name: betA [C]

Synonym: mlr3058

Alternate gene names: 13472686

Gene position: 2462766-2464394 (Clockwise)

Preceding gene: 13472685

Following gene: 13472687

Centisome position: 35.0

GC content: 65.07

Gene sequence:

>1629_bases
ATGACCGACTACATCATCGTGGGCGCCGGCCCGGCCGGCTGTGTTCTGGCCAACCGGCTGAGCGAGGACCCCGGCAATTC
CGTGCTGCTTCTGGAAGCCGGCGGCAAGGACTGGCATCCCTACATCCACATGCCGGCGGGCTTCGCCAAGATGACCAAGG
GCATTGCGTCCTGGGGCTGGTCCACCGTGCCGCAGAAAAACATGAAGGACCGCGTCTTCTGGTACACACAGGCCAAGGTG
GTCGGCGGCGGCTCCTCCATCAACGCCCAGATCTACACACGCGGCAATGCCCGCGACTATGACGCCTGGGAGAAGGAAGA
GGGTCTCGCCGGCTGGGGCTACCGCGACGTGCTGCCCTATTTCAAGCGCGCCGAGAACAACCAGCGTTTCGCCAACGACT
TTCATGGCGACCAGGGGCCGCTCGGCGTATCGAACCCGATCTCGCCGCTGCCGATCTGCGAAGCCTATTTCCGCGCCGGC
CAGGAGATGGGCATCCCCTTCAACCCGGACTTCAACGGCGCCAACCAAGAAGGCGTCGGCTATTACCAGCTCACCCAGAA
GGATGCCCGGCGCTCCTCGGCCTCGGTCGCCTATCTCAAGCCGATCCGTGCGCGCAAGAACCTGACGGTCAGGACCGATG
TGCTGGTGACCCGCATCGTCGTCGAGAAGGGCCGCGCTGTCGGCGTTGAAGTCGTCGACCGGCCAGGCGGCGAGAAGAAG
ATCCTGCACGCCGAGCGCGAGGTGATCGTCTCGTCCGGCGCCATCGGCTCGCCGAAGCTTTTGATGCAATCGGGGATCGG
TCCGGCCGACCACCTGAAATCGGTGGGCGTGACGCCGGTGCATGACCTGCCTGGAGTCGGCTCCAACATGCAGGATCATC
TCGATCTGTTCGTCATCGCCGAATGCACTGGTGACCACACCTACGACAATTACGCCAAGCTGCACCGCACGGCCTGGGCC
GGCCTGCAATATCTGTTGCTGAAGAAAGGGCCCGTGGCCTCCAGCCTGTTCGAGACCGGCGGCTTCTGGTACGCCGACCC
GACGGCCGCCTCGCCCGACATCCAGTTCCATCTCGGCCTGGGATCCGGCATCGAGGCCGGCGTCGAGAAACTGAACAACC
CCGGCGTCACCTTGAACTCGGCTTTCCTGCGGCCGCGCTCGCGCGGCACGGTGCGGCTGAAGAGCGCCGACCCGGCCAAC
CATCCGCTTATCGATCCGAACTACTGGTCCGATCCCTATGACCGCGCCATGTCGATCAAGGGGTTGCGGCTGGCGCGCGA
AATCATGCGTCAGAAGGCACTTGAGCCCTACGTGCTGCGCGAAGTGCTGCCCGGTCCGTCGCTGGCTAGCGACGACGAAC
TGTTCGACTATGCCTGCCGCAGCGCAAAGACCGACCACCATCCAGTCGGCACCTGCCGCATGGGCCATGACGAGATGGCC
GTCGTGACGCCGGACCTGCGGCTGCGCGGCATCGAAGGCCTGCGCGTCTGCGACGCCTCGGTGATGCCGCGCGTGCCCTC
CTCCAACACCAATGCACCGACCATCATGGTCGGCGAAAAGGGTGCCGACCTGATCCTTGGCCGCGAACCGCTGCCGCCGG
CGGTGTTTTCCGGCAACCGGGCCGCTTGA

Upstream 100 bases:

>100_bases
TGGTGGCGACGCTTGCCGCCGGCAGGCTCGGCTTTTCGACCGGCTCGATCATCAATGTCGACGGCGCGCTCTCCGTGCCG
CGGCTGTAGGTGGAAACGAC

Downstream 100 bases:

>100_bases
AGGGAAAAGAAAATGATCAGGCACTGTGTCTTCGTCAGGTTTCGCGGCGATGTCCCCGAAAGCGAGCGCGCTGCAATCCA
TGCCGACCTCGAGGCGCTGC

Product: dehydrogenase, (L-sorbose dehydrogenase, GMC oxidoreductase, glycol dehydrogenase, alcohol dehydrogenase)

Products: NA

Alternate protein names: SDH [H]

Number of amino acids: Translated: 542; Mature: 541

Protein sequence:

>542_residues
MTDYIIVGAGPAGCVLANRLSEDPGNSVLLLEAGGKDWHPYIHMPAGFAKMTKGIASWGWSTVPQKNMKDRVFWYTQAKV
VGGGSSINAQIYTRGNARDYDAWEKEEGLAGWGYRDVLPYFKRAENNQRFANDFHGDQGPLGVSNPISPLPICEAYFRAG
QEMGIPFNPDFNGANQEGVGYYQLTQKDARRSSASVAYLKPIRARKNLTVRTDVLVTRIVVEKGRAVGVEVVDRPGGEKK
ILHAEREVIVSSGAIGSPKLLMQSGIGPADHLKSVGVTPVHDLPGVGSNMQDHLDLFVIAECTGDHTYDNYAKLHRTAWA
GLQYLLLKKGPVASSLFETGGFWYADPTAASPDIQFHLGLGSGIEAGVEKLNNPGVTLNSAFLRPRSRGTVRLKSADPAN
HPLIDPNYWSDPYDRAMSIKGLRLAREIMRQKALEPYVLREVLPGPSLASDDELFDYACRSAKTDHHPVGTCRMGHDEMA
VVTPDLRLRGIEGLRVCDASVMPRVPSSNTNAPTIMVGEKGADLILGREPLPPAVFSGNRAA

Sequences:

>Translated_542_residues
MTDYIIVGAGPAGCVLANRLSEDPGNSVLLLEAGGKDWHPYIHMPAGFAKMTKGIASWGWSTVPQKNMKDRVFWYTQAKV
VGGGSSINAQIYTRGNARDYDAWEKEEGLAGWGYRDVLPYFKRAENNQRFANDFHGDQGPLGVSNPISPLPICEAYFRAG
QEMGIPFNPDFNGANQEGVGYYQLTQKDARRSSASVAYLKPIRARKNLTVRTDVLVTRIVVEKGRAVGVEVVDRPGGEKK
ILHAEREVIVSSGAIGSPKLLMQSGIGPADHLKSVGVTPVHDLPGVGSNMQDHLDLFVIAECTGDHTYDNYAKLHRTAWA
GLQYLLLKKGPVASSLFETGGFWYADPTAASPDIQFHLGLGSGIEAGVEKLNNPGVTLNSAFLRPRSRGTVRLKSADPAN
HPLIDPNYWSDPYDRAMSIKGLRLAREIMRQKALEPYVLREVLPGPSLASDDELFDYACRSAKTDHHPVGTCRMGHDEMA
VVTPDLRLRGIEGLRVCDASVMPRVPSSNTNAPTIMVGEKGADLILGREPLPPAVFSGNRAA
>Mature_541_residues
TDYIIVGAGPAGCVLANRLSEDPGNSVLLLEAGGKDWHPYIHMPAGFAKMTKGIASWGWSTVPQKNMKDRVFWYTQAKVV
GGGSSINAQIYTRGNARDYDAWEKEEGLAGWGYRDVLPYFKRAENNQRFANDFHGDQGPLGVSNPISPLPICEAYFRAGQ
EMGIPFNPDFNGANQEGVGYYQLTQKDARRSSASVAYLKPIRARKNLTVRTDVLVTRIVVEKGRAVGVEVVDRPGGEKKI
LHAEREVIVSSGAIGSPKLLMQSGIGPADHLKSVGVTPVHDLPGVGSNMQDHLDLFVIAECTGDHTYDNYAKLHRTAWAG
LQYLLLKKGPVASSLFETGGFWYADPTAASPDIQFHLGLGSGIEAGVEKLNNPGVTLNSAFLRPRSRGTVRLKSADPANH
PLIDPNYWSDPYDRAMSIKGLRLAREIMRQKALEPYVLREVLPGPSLASDDELFDYACRSAKTDHHPVGTCRMGHDEMAV
VTPDLRLRGIEGLRVCDASVMPRVPSSNTNAPTIMVGEKGADLILGREPLPPAVFSGNRAA

Specific function: Can Catalyze The Oxidation Of Choline To Betaine Aldehyde And Betaine Aldehyde To Glycine Betaine At The Same Rate. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=540, Percent_Identity=42.037037037037, Blast_Score=403, Evalue=1e-112,
Organism=Escherichia coli, GI1786503, Length=535, Percent_Identity=41.3084112149533, Blast_Score=383, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17532301, Length=551, Percent_Identity=39.7459165154265, Blast_Score=388, Evalue=1e-108,
Organism=Drosophila melanogaster, GI24642055, Length=578, Percent_Identity=36.159169550173, Blast_Score=325, Evalue=5e-89,
Organism=Drosophila melanogaster, GI24642042, Length=564, Percent_Identity=37.2340425531915, Blast_Score=308, Evalue=6e-84,
Organism=Drosophila melanogaster, GI17137792, Length=553, Percent_Identity=36.3471971066908, Blast_Score=305, Evalue=7e-83,
Organism=Drosophila melanogaster, GI24642048, Length=564, Percent_Identity=36.7021276595745, Blast_Score=300, Evalue=1e-81,
Organism=Drosophila melanogaster, GI45551458, Length=569, Percent_Identity=37.0826010544815, Blast_Score=298, Evalue=5e-81,
Organism=Drosophila melanogaster, GI45549471, Length=570, Percent_Identity=37.3684210526316, Blast_Score=298, Evalue=5e-81,
Organism=Drosophila melanogaster, GI24642039, Length=563, Percent_Identity=35.7015985790409, Blast_Score=292, Evalue=4e-79,
Organism=Drosophila melanogaster, GI24650267, Length=576, Percent_Identity=35.9375, Blast_Score=292, Evalue=4e-79,
Organism=Drosophila melanogaster, GI24642059, Length=570, Percent_Identity=36.140350877193, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24642037, Length=571, Percent_Identity=36.6024518388792, Blast_Score=285, Evalue=5e-77,
Organism=Drosophila melanogaster, GI18859995, Length=564, Percent_Identity=34.2198581560284, Blast_Score=277, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24642035, Length=569, Percent_Identity=34.4463971880492, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI18859993, Length=568, Percent_Identity=35.7394366197183, Blast_Score=258, Evalue=5e-69,
Organism=Drosophila melanogaster, GI24642051, Length=568, Percent_Identity=32.0422535211268, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24645930, Length=573, Percent_Identity=27.9232111692845, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24642057, Length=587, Percent_Identity=29.3015332197615, Blast_Score=155, Evalue=7e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.32 [H]

Molecular weight: Translated: 59014; Mature: 58882

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: PS00623 GMC_OXRED_1 ; PS00624 GMC_OXRED_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDYIIVGAGPAGCVLANRLSEDPGNSVLLLEAGGKDWHPYIHMPAGFAKMTKGIASWGW
CCCEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEECCCCHHHHHHHHHHCCC
STVPQKNMKDRVFWYTQAKVVGGGSSINAQIYTRGNARDYDAWEKEEGLAGWGYRDVLPY
CCCCCCCCCCEEEEEEEEEEEECCCCEEEEEEECCCCCCCCCCHHCCCCCCCCHHHHHHH
FKRAENNQRFANDFHGDQGPLGVSNPISPLPICEAYFRAGQEMGIPFNPDFNGANQEGVG
HHHCCCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCE
YYQLTQKDARRSSASVAYLKPIRARKNLTVRTDVLVTRIVVEKGRAVGVEVVDRPGGEKK
EEEECHHHHHHCCCCEEEEEHHHHCCCCEEEHHHHHHHHHHHCCCEEEEEEEECCCCCCH
ILHAEREVIVSSGAIGSPKLLMQSGIGPADHLKSVGVTPVHDLPGVGSNMQDHLDLFVIA
HHHHHHHEEEECCCCCCCHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCHHHCCEEEEEE
ECTGDHTYDNYAKLHRTAWAGLQYLLLKKGPVASSLFETGGFWYADPTAASPDIQFHLGL
ECCCCCCHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHCCCEEEECCCCCCCCEEEEEEC
GSGIEAGVEKLNNPGVTLNSAFLRPRSRGTVRLKSADPANHPLIDPNYWSDPYDRAMSIK
CCCHHHHHHHHCCCCEEEEHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
GLRLAREIMRQKALEPYVLREVLPGPSLASDDELFDYACRSAKTDHHPVGTCRMGHDEMA
HHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCEE
VVTPDLRLRGIEGLRVCDASVMPRVPSSNTNAPTIMVGEKGADLILGREPLPPAVFSGNR
EECCCCEEECCCCEEEECCHHCCCCCCCCCCCCEEEECCCCCCEEECCCCCCCHHCCCCC
AA
CC
>Mature Secondary Structure 
TDYIIVGAGPAGCVLANRLSEDPGNSVLLLEAGGKDWHPYIHMPAGFAKMTKGIASWGW
CCEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEECCCCHHHHHHHHHHCCC
STVPQKNMKDRVFWYTQAKVVGGGSSINAQIYTRGNARDYDAWEKEEGLAGWGYRDVLPY
CCCCCCCCCCEEEEEEEEEEEECCCCEEEEEEECCCCCCCCCCHHCCCCCCCCHHHHHHH
FKRAENNQRFANDFHGDQGPLGVSNPISPLPICEAYFRAGQEMGIPFNPDFNGANQEGVG
HHHCCCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCE
YYQLTQKDARRSSASVAYLKPIRARKNLTVRTDVLVTRIVVEKGRAVGVEVVDRPGGEKK
EEEECHHHHHHCCCCEEEEEHHHHCCCCEEEHHHHHHHHHHHCCCEEEEEEEECCCCCCH
ILHAEREVIVSSGAIGSPKLLMQSGIGPADHLKSVGVTPVHDLPGVGSNMQDHLDLFVIA
HHHHHHHEEEECCCCCCCHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCHHHCCEEEEEE
ECTGDHTYDNYAKLHRTAWAGLQYLLLKKGPVASSLFETGGFWYADPTAASPDIQFHLGL
ECCCCCCHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHCCCEEEECCCCCCCCEEEEEEC
GSGIEAGVEKLNNPGVTLNSAFLRPRSRGTVRLKSADPANHPLIDPNYWSDPYDRAMSIK
CCCHHHHHHHHCCCCEEEEHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
GLRLAREIMRQKALEPYVLREVLPGPSLASDDELFDYACRSAKTDHHPVGTCRMGHDEMA
HHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCEE
VVTPDLRLRGIEGLRVCDASVMPRVPSSNTNAPTIMVGEKGADLILGREPLPPAVFSGNR
EECCCCEEECCCCEEEECCHHCCCCCCCCCCCCEEEECCCCCCEEECCCCCCCHHCCCCC
AA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9023923 [H]