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The map label for this gene is hss

Identifier: 13472649

GI number: 13472649

Start: 2417878

End: 2419335

Strand: Direct

Name: hss

Synonym: mlr3014

Alternate gene names: 13472649

Gene position: 2417878-2419335 (Clockwise)

Preceding gene: 13472648

Following gene: 13472650

Centisome position: 34.36

GC content: 63.24

Gene sequence:

>1458_bases
GTGCTCGATAAAATGGCGAATGAAAACTGGCCCGTTTACGGTGAGATCACCGGCCCTGTGGTGATGATCGGCTTCGGCTC
GATCGGACGGGGGACGCTGCCGCTCATCGAACGCCATTTCAAGTTCGACAAGTCGCGCATGACGGTCCTCGACCCACGCG
ACACCGACCGCAAGCTGCTCGACGAGCGCGGCATCGCCTTCGTCCAGGAAGCGGTGACCGAGAACAACTACAAGAAACTT
CTGACGCCGCTTTTGACCAATGGCGGCGGCCAGGGCTTTTGCGTCAACCTGTCGGTCGATACCGGCTCGGTGGATCTGAT
GCGGCTCTGCCGCAAGCTCGGCGTGCTCTACATCGATACCGTCGTCGAGCCGTGGCTCGGCTTCTATTTCGACGCCAAGG
CCGACAATGCCAGCCGCACCAACTATGCGCTGCGCGAAGCGATGATCAAGGAAAAGCACGACAAGCCCGGCGGCGCCACC
GTCGTCTCCACCTGTGGTGCCAATCCCGGCATGGTCTCGTGGTTCGTCAAGCAGGCGCTGGTCAACCTCGCCACCGATCT
TGGCCTGGAGTTCTCGGAGCCGGCGCAGGAAGACCGCGAGGGTTGGGCCAAGCTGATGAAGAAGGCCGGCGTCAAGGGCA
TCCATATCGCCGAGCGCGACACCCAGCGCACCAAGAAGCCGAAACCGATGGATGTGTTCTGGAACACCTGGTCGGTCGAG
GGCTTCATCTCCGAGGGATTGCAGCCGGCCGAGCTCGGCTGGGGAACGCATGAGAAGTGGATGCCGAAGAACGGCAAGAA
GCACAAGCATGGCTCCAAGGCCGCGATCTATCTGGAGCAGCCCGGCGCCAACACGCGCGTGCGCTCGTGGTGCCCGACGC
CGGGCGCGCAATACGGCCTGCTGGTGACGCACAACGAGGCGATCTCGATCGCCGATTTCTTCACCGTTCGCTCCAAGAAG
GGCAAGGTCCAGTACCGGCCGACCTGCCACTATGCCTACCATCCCTCCAACGACGCGATGCTGTCGCTGGACGAGATGTT
CGGCGCCGCCGGCAAGCCTCAGCCGGTGCACCACGTGCTCGACGAGAACGAACTGGTCGACGGTGTCGACGAGCTCGGCG
TCCTGCTCTACGGCCACGACAAGAATGCCTACTGGTACGGCTCGCAGCTGTCGCTCGCCGAGGCGCGCAAGCTGGCGCCC
TATCAGAACGCCACCGGCATGCAGGTCACCTCGGCGGTTCTGGCGGGCATGGTCTGGGCGCTGGAAAATCCGGATGCCGG
CATCGTCGAGGCCGACGAGATGGACTACAAGCGCTGCCTGGACGTGCAGTCGCCCTATCTTGGACCGGTCAAAGGCTATT
ACACCGACTGGACGCCGCTCGACCGACGCCCGGGACTCTTCCCGGAGGACCTCGACCGCAGCGATCCGTGGCAATTCCGC
AACATCCTCGTGCGATAG

Upstream 100 bases:

>100_bases
GGCGTTCCCGGGCGTTTCGCTGCTTTTCCCTTTATTGTGACAATGATCTATGGTTTGTCGCGCCGCGGCCAAGCGGCTGT
TCCGGAGTGTTTTTTGAGGA

Downstream 100 bases:

>100_bases
CACCTCGCGCACTATGCGCCATTGCCTTGCAATCGCCCGGAAATCGGGCGATTGAAGAGATGCGGCCTGGGGCAGCGTGC
GTCTTGCGGGACGCCCGCCC

Product: homospermidine synthase

Products: NA

Alternate protein names: HSS

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MLDKMANENWPVYGEITGPVVMIGFGSIGRGTLPLIERHFKFDKSRMTVLDPRDTDRKLLDERGIAFVQEAVTENNYKKL
LTPLLTNGGGQGFCVNLSVDTGSVDLMRLCRKLGVLYIDTVVEPWLGFYFDAKADNASRTNYALREAMIKEKHDKPGGAT
VVSTCGANPGMVSWFVKQALVNLATDLGLEFSEPAQEDREGWAKLMKKAGVKGIHIAERDTQRTKKPKPMDVFWNTWSVE
GFISEGLQPAELGWGTHEKWMPKNGKKHKHGSKAAIYLEQPGANTRVRSWCPTPGAQYGLLVTHNEAISIADFFTVRSKK
GKVQYRPTCHYAYHPSNDAMLSLDEMFGAAGKPQPVHHVLDENELVDGVDELGVLLYGHDKNAYWYGSQLSLAEARKLAP
YQNATGMQVTSAVLAGMVWALENPDAGIVEADEMDYKRCLDVQSPYLGPVKGYYTDWTPLDRRPGLFPEDLDRSDPWQFR
NILVR

Sequences:

>Translated_485_residues
MLDKMANENWPVYGEITGPVVMIGFGSIGRGTLPLIERHFKFDKSRMTVLDPRDTDRKLLDERGIAFVQEAVTENNYKKL
LTPLLTNGGGQGFCVNLSVDTGSVDLMRLCRKLGVLYIDTVVEPWLGFYFDAKADNASRTNYALREAMIKEKHDKPGGAT
VVSTCGANPGMVSWFVKQALVNLATDLGLEFSEPAQEDREGWAKLMKKAGVKGIHIAERDTQRTKKPKPMDVFWNTWSVE
GFISEGLQPAELGWGTHEKWMPKNGKKHKHGSKAAIYLEQPGANTRVRSWCPTPGAQYGLLVTHNEAISIADFFTVRSKK
GKVQYRPTCHYAYHPSNDAMLSLDEMFGAAGKPQPVHHVLDENELVDGVDELGVLLYGHDKNAYWYGSQLSLAEARKLAP
YQNATGMQVTSAVLAGMVWALENPDAGIVEADEMDYKRCLDVQSPYLGPVKGYYTDWTPLDRRPGLFPEDLDRSDPWQFR
NILVR
>Mature_485_residues
MLDKMANENWPVYGEITGPVVMIGFGSIGRGTLPLIERHFKFDKSRMTVLDPRDTDRKLLDERGIAFVQEAVTENNYKKL
LTPLLTNGGGQGFCVNLSVDTGSVDLMRLCRKLGVLYIDTVVEPWLGFYFDAKADNASRTNYALREAMIKEKHDKPGGAT
VVSTCGANPGMVSWFVKQALVNLATDLGLEFSEPAQEDREGWAKLMKKAGVKGIHIAERDTQRTKKPKPMDVFWNTWSVE
GFISEGLQPAELGWGTHEKWMPKNGKKHKHGSKAAIYLEQPGANTRVRSWCPTPGAQYGLLVTHNEAISIADFFTVRSKK
GKVQYRPTCHYAYHPSNDAMLSLDEMFGAAGKPQPVHHVLDENELVDGVDELGVLLYGHDKNAYWYGSQLSLAEARKLAP
YQNATGMQVTSAVLAGMVWALENPDAGIVEADEMDYKRCLDVQSPYLGPVKGYYTDWTPLDRRPGLFPEDLDRSDPWQFR
NILVR

Specific function: Involved in the NAD(+)-dependent synthesis of the polyamine homospermidine from putrescine

COG id: COG5310

COG function: function code Q; Homospermidine synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSS_RHILO (Q98H64)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_104216.1
- ProteinModelPortal:   Q98H64
- SMR:   Q98H64
- GeneID:   1226877
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr3014
- NMPDR:   fig|266835.1.peg.2320
- HOGENOM:   HBG299479
- OMA:   ESISIAD
- ProtClustDB:   CLSK863630
- BRENDA:   2.5.1.44
- GO:   GO:0005488
- InterPro:   IPR023181
- InterPro:   IPR016040
- InterPro:   IPR005097
- Gene3D:   G3DSA:3.40.50.720

Pfam domain/function: PF03435 Saccharop_dh

EC number: =2.5.1.44

Molecular weight: Translated: 54248; Mature: 54248

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDKMANENWPVYGEITGPVVMIGFGSIGRGTLPLIERHFKFDKSRMTVLDPRDTDRKLL
CCCCCCCCCCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHH
DERGIAFVQEAVTENNYKKLLTPLLTNGGGQGFCVNLSVDTGSVDLMRLCRKLGVLYIDT
HHCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHCCEEEEHH
VVEPWLGFYFDAKADNASRTNYALREAMIKEKHDKPGGATVVSTCGANPGMVSWFVKQAL
HHHHHHCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHH
VNLATDLGLEFSEPAQEDREGWAKLMKKAGVKGIHIAERDTQRTKKPKPMDVFWNTWSVE
HHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHCCCCCCCEEEEECEEEH
GFISEGLQPAELGWGTHEKWMPKNGKKHKHGSKAAIYLEQPGANTRVRSWCPTPGAQYGL
HHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEECCCCCCCEEE
LVTHNEAISIADFFTVRSKKGKVQYRPTCHYAYHPSNDAMLSLDEMFGAAGKPQPVHHVL
EEECCCCEEHHHHHEEECCCCCEEECCCEEEEECCCCCCEEEHHHHHCCCCCCCHHHHHC
DENELVDGVDELGVLLYGHDKNAYWYGSQLSLAEARKLAPYQNATGMQVTSAVLAGMVWA
CCHHHHCCHHHCCEEEEECCCCCEEECCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHE
LENPDAGIVEADEMDYKRCLDVQSPYLGPVKGYYTDWTPLDRRPGLFPEDLDRSDPWQFR
ECCCCCCCEECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHH
NILVR
HHHCC
>Mature Secondary Structure
MLDKMANENWPVYGEITGPVVMIGFGSIGRGTLPLIERHFKFDKSRMTVLDPRDTDRKLL
CCCCCCCCCCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHH
DERGIAFVQEAVTENNYKKLLTPLLTNGGGQGFCVNLSVDTGSVDLMRLCRKLGVLYIDT
HHCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHCCEEEEHH
VVEPWLGFYFDAKADNASRTNYALREAMIKEKHDKPGGATVVSTCGANPGMVSWFVKQAL
HHHHHHCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHH
VNLATDLGLEFSEPAQEDREGWAKLMKKAGVKGIHIAERDTQRTKKPKPMDVFWNTWSVE
HHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHCCCCCCCEEEEECEEEH
GFISEGLQPAELGWGTHEKWMPKNGKKHKHGSKAAIYLEQPGANTRVRSWCPTPGAQYGL
HHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEECCCCCCCEEE
LVTHNEAISIADFFTVRSKKGKVQYRPTCHYAYHPSNDAMLSLDEMFGAAGKPQPVHHVL
EEECCCCEEHHHHHEEECCCCCEEECCCEEEEECCCCCCEEEHHHHHCCCCCCCHHHHHC
DENELVDGVDELGVLLYGHDKNAYWYGSQLSLAEARKLAPYQNATGMQVTSAVLAGMVWA
CCHHHHCCHHHCCEEEEECCCCCEEECCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHE
LENPDAGIVEADEMDYKRCLDVQSPYLGPVKGYYTDWTPLDRRPGLFPEDLDRSDPWQFR
ECCCCCCCEECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHH
NILVR
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968