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The map label for this gene is ctrA [H]

Identifier: 13472497

GI number: 13472497

Start: 2256556

End: 2257251

Strand: Reverse

Name: ctrA [H]

Synonym: mll2816

Alternate gene names: 13472497

Gene position: 2257251-2256556 (Counterclockwise)

Preceding gene: 13472499

Following gene: 13472494

Centisome position: 32.08

GC content: 59.2

Gene sequence:

>696_bases
ATGCGTGTTCTGCTGATAGAAGATGACAGTGCAACCGCACAAAGCATCGAACTGATGCTGAAATCGGAGAGTTTCAATGT
CTATACGACGGACCTCGGCGAAGAGGGTGTCGATCTGGGCAAACTCTACGACTACGACATCATCCTTCTCGATCTCAACC
TGCCCGACATGTCCGGCTACGAGGTCTTGAGAACGCTTCGCCTCTCCAAGGTAAAGACGCCGATCCTGATCCTCTCCGGC
ATGGCCGGCATCGAGGACAAGGTCCGTGGCCTCGGCTTCGGCGCTGACGACTACATGACCAAGCCGTTCCACAAGGACGA
GCTGGTGGCCCGCATCCATGCCATCGTGCGACGCTCCAAGGGCCATGCCCAGTCGGTCATCACCACCGGTGACCTGGTGG
TCAACCTCGACGCCAAGACCGTCGAGGTCGGCGGCCAGCGCGTGCACCTCACCGGCAAGGAATACCAGATGCTGGAGCTG
CTCTCGCTGCGCAAGGGCACAACGCTCACCAAGGAAATGTTCCTCAACCACCTCTATGGCGGCATGGACGAGCCGGAATT
GAAGATCATCGACGTCTTCATCTGCAAATTGCGCAAGAAGCTCGACGCCGCATCCGGTGGCCAGAACTACATCGAGACGG
TCTGGGGCCGCGGCTACGTGCTGCGCGAACCCGAAGACATCCGCGTCAGCGCCTGA

Upstream 100 bases:

>100_bases
GGTTTTGTTAACCATTCGATGGCAGCCTCTGCACAAGGCAACCACTGCTCCGGGGCAGGACGGGTCGTGAAATGGTCCGG
CGGCAGAAAAGGGGAATGAA

Downstream 100 bases:

>100_bases
GCGGCGAGCACCGCCCGAATCATTGCCATGTCAGACTAAAAACCCGGCTTCGGCCGGGTTTTTGCGTCACGGATCAGCGA
TGAAAGGGCTCTGCCGCCTC

Product: two-component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MRVLLIEDDSATAQSIELMLKSESFNVYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGYEVLRTLRLSKVKTPILILSG
MAGIEDKVRGLGFGADDYMTKPFHKDELVARIHAIVRRSKGHAQSVITTGDLVVNLDAKTVEVGGQRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLDAASGGQNYIETVWGRGYVLREPEDIRVSA

Sequences:

>Translated_231_residues
MRVLLIEDDSATAQSIELMLKSESFNVYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGYEVLRTLRLSKVKTPILILSG
MAGIEDKVRGLGFGADDYMTKPFHKDELVARIHAIVRRSKGHAQSVITTGDLVVNLDAKTVEVGGQRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLDAASGGQNYIETVWGRGYVLREPEDIRVSA
>Mature_231_residues
MRVLLIEDDSATAQSIELMLKSESFNVYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGYEVLRTLRLSKVKTPILILSG
MAGIEDKVRGLGFGADDYMTKPFHKDELVARIHAIVRRSKGHAQSVITTGDLVVNLDAKTVEVGGQRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLDAASGGQNYIETVWGRGYVLREPEDIRVSA

Specific function: Essential protein that plays a role in the control of cell division, possibly through the transcriptional regulation of ccrM, rpoD, pleC, minC and ftsZ genes [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=35.8078602620087, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=34.9557522123894, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=34.5291479820628, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=33.9366515837104, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=33.6363636363636, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=32.8947368421053, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=31.6742081447964, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=30.5936073059361, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=29.5154185022026, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=30.6306306306306, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=31.2217194570136, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=30.8370044052863, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=25.5506607929515, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=27.9661016949153, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790437, Length=160, Percent_Identity=25, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1789149, Length=145, Percent_Identity=28.2758620689655, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=25.1063829787234, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25835; Mature: 25835

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLIEDDSATAQSIELMLKSESFNVYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGY
CEEEEEECCCCHHHHEEEEEECCCCEEEECCCCCCCCCCCEEECEEEEEEEECCCCCCHH
EVLRTLRLSKVKTPILILSGMAGIEDKVRGLGFGADDYMTKPFHKDELVARIHAIVRRSK
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHCCC
GHAQSVITTGDLVVNLDAKTVEVGGQRVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYG
CCHHEEEEECCEEEEECCEEEEECCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLDAASGGQNYIETVWGRGYVLREPEDIRVSA
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEECCCCCEECC
>Mature Secondary Structure
MRVLLIEDDSATAQSIELMLKSESFNVYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGY
CEEEEEECCCCHHHHEEEEEECCCCEEEECCCCCCCCCCCEEECEEEEEEEECCCCCCHH
EVLRTLRLSKVKTPILILSGMAGIEDKVRGLGFGADDYMTKPFHKDELVARIHAIVRRSK
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHCCC
GHAQSVITTGDLVVNLDAKTVEVGGQRVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYG
CCHHEEEEECCEEEEECCEEEEECCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLDAASGGQNYIETVWGRGYVLREPEDIRVSA
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEECCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA