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The map label for this gene is yddQ [H]

Identifier: 13472460

GI number: 13472460

Start: 2219749

End: 2220393

Strand: Reverse

Name: yddQ [H]

Synonym: mll2765

Alternate gene names: 13472460

Gene position: 2220393-2219749 (Counterclockwise)

Preceding gene: 13472462

Following gene: 13472450

Centisome position: 31.56

GC content: 65.27

Gene sequence:

>645_bases
ATGTCTGACAGAGCCAACACCACGCCGCGCCGCGCGCTCATCGTCGTCGACGTCCAGAACGACTATGACGGCGGCAATCT
GGCCATCCAGCATCCGCCGTTCCGCGACAGCGTCGTCAATGTGGCACGCGCCATGGATGCGGCGACGGCCGCCGGCATCA
AGGTCGTGGTCGTCAAGCAGATGGCGCCCGAGACCTCGCCGATCTTCGCCAAGGGTAGCCACGGCGGCGAACTGCATCCG
GAAATCGCCAGGCGCGGCCGCGACCATTATGTCGAGAAGATGCTGCCCTCGGCCTTCACCGGCACCGACCTCGAGGCGTG
GCTGCGCGCCAACGCCATCGATACGCTCACGGTGGTCGGCTACATGACGCATAATTGCGACCTGTCGACCATCATCCATG
CCGTGCATATGGGTTTCGCCGTCGAGTTCCTGTCCGACGCGACCGGCTCGGTGCCCTATGCCAACAGCGCCGGCTATGCC
TCGGCCGAGGAGATCCACCGCGTGGTCACGATCATCCTGCAGTCACGTTTCGCGGCCGTACTGAAGACCGCCGAATGGGT
CGAGCGCCTGAAGACCGGCGCCTTGCCGGAACGTGACACGATTTACGCCTCCAACCAGCGGGCGCTGGCGCGCAACGCGG
CGTAG

Upstream 100 bases:

>100_bases
TGTCCCAATTCTTTCGAATGATGTCAACTGGGCCACTTTTGGCCGCTCATCGACCGGCTTATTTTCGGCCCATCGCATTC
AGGCCGAAAAGGAAAACACC

Downstream 100 bases:

>100_bases
GAATATCCGCAAACAGAAAGGGCGCTGCATCGCTGCGGCGCCCTTTGCCGTTTGGAATTTGAAGATTCTAGAACAGGCCT
TCGATCTGGCCGGCCTCGTT

Product: hypothetical protein

Products: Nicotinate; pyrazinoic acid; NH3 [C]

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MSDRANTTPRRALIVVDVQNDYDGGNLAIQHPPFRDSVVNVARAMDAATAAGIKVVVVKQMAPETSPIFAKGSHGGELHP
EIARRGRDHYVEKMLPSAFTGTDLEAWLRANAIDTLTVVGYMTHNCDLSTIIHAVHMGFAVEFLSDATGSVPYANSAGYA
SAEEIHRVVTIILQSRFAAVLKTAEWVERLKTGALPERDTIYASNQRALARNAA

Sequences:

>Translated_214_residues
MSDRANTTPRRALIVVDVQNDYDGGNLAIQHPPFRDSVVNVARAMDAATAAGIKVVVVKQMAPETSPIFAKGSHGGELHP
EIARRGRDHYVEKMLPSAFTGTDLEAWLRANAIDTLTVVGYMTHNCDLSTIIHAVHMGFAVEFLSDATGSVPYANSAGYA
SAEEIHRVVTIILQSRFAAVLKTAEWVERLKTGALPERDTIYASNQRALARNAA
>Mature_213_residues
SDRANTTPRRALIVVDVQNDYDGGNLAIQHPPFRDSVVNVARAMDAATAAGIKVVVVKQMAPETSPIFAKGSHGGELHPE
IARRGRDHYVEKMLPSAFTGTDLEAWLRANAIDTLTVVGYMTHNCDLSTIIHAVHMGFAVEFLSDATGSVPYANSAGYAS
AEEIHRVVTIILQSRFAAVLKTAEWVERLKTGALPERDTIYASNQRALARNAA

Specific function: NAD biosynthesis; nicotinamide to NaMN; first step. [C]

COG id: COG1335

COG function: function code Q; Amidases related to nicotinamidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismatase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000868 [H]

Pfam domain/function: PF00857 Isochorismatase [H]

EC number: 3.5.1.- [C]

Molecular weight: Translated: 23198; Mature: 23066

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRANTTPRRALIVVDVQNDYDGGNLAIQHPPFRDSVVNVARAMDAATAAGIKVVVVKQ
CCCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEEEC
MAPETSPIFAKGSHGGELHPEIARRGRDHYVEKMLPSAFTGTDLEAWLRANAIDTLTVVG
CCCCCCCEEEECCCCCCCCHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHEE
YMTHNCDLSTIIHAVHMGFAVEFLSDATGSVPYANSAGYASAEEIHRVVTIILQSRFAAV
HHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LKTAEWVERLKTGALPERDTIYASNQRALARNAA
HHHHHHHHHHHHCCCCCCCEEEECCCHHHHCCCC
>Mature Secondary Structure 
SDRANTTPRRALIVVDVQNDYDGGNLAIQHPPFRDSVVNVARAMDAATAAGIKVVVVKQ
CCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEEEC
MAPETSPIFAKGSHGGELHPEIARRGRDHYVEKMLPSAFTGTDLEAWLRANAIDTLTVVG
CCCCCCCEEEECCCCCCCCHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHEE
YMTHNCDLSTIIHAVHMGFAVEFLSDATGSVPYANSAGYASAEEIHRVVTIILQSRFAAV
HHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LKTAEWVERLKTGALPERDTIYASNQRALARNAA
HHHHHHHHHHHHCCCCCCCEEEECCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Nicotinamide; pyrazinamide; H2O [C]

Specific reaction: Nicotinamide + H2O = Nicotinate + NH3 pyrazinamide + H2O = pyrazinoic acid + NH3 [C]

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]