Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 13472444

GI number: 13472444

Start: 2201129

End: 2201845

Strand: Direct

Name: ompR [H]

Synonym: mlr2740

Alternate gene names: 13472444

Gene position: 2201129-2201845 (Clockwise)

Preceding gene: 13472440

Following gene: 13472445

Centisome position: 31.28

GC content: 65.13

Gene sequence:

>717_bases
GTGAAATCCGACGCACACATACTGATCGTCGACGACGACAAGGGCATCCGCGACCTGCTTCAGGAATTCTTCCAGAAGCG
GGGGCTGCACACTTCGGTTGCCGCGGACGGTACCGAGATGGAGGCCGTCCTGCGCCGCGCGCAGGTGGACCTCATCGTGC
TCGACGTGATGTTGCCCGGCAAGAGCGGGCTGGAACTGTGCCGCGATCTGCGCGCCCAGTACTCGACGCCGATCATCATG
CTGACCGCCGTCACCGAGACCACCGACCGCGTCGTCGGCCTGGAAATGGGCGCCGACGACTATGTGCCCAAGCCCTTCGA
TCCGCGCGAACTCCTGGCGCGCATCCGTGCCGTGCTGCGGCGCAATGGTGCCGCCGAGCCGAAGCGCGCCACCGCCAAGC
AGATCTACCGTTTCGCCGGCTGGACGATGGACTGTTCGCGGCGCCGGCTGACGGCGCCCGACGATGTCAGGGTCGAGCTC
ACCATGGCCGAATTCAACCTGCTGCAGACCTTCGTCAAGAGCGCCCAGCGCGTGCTGACCCGCGACCAGCTCATCGAACT
CTCCGGCGGCGACAGCGACTATTCCTTCGACCGCAGCATCGACATCCTGGTCAGCCGGCTGCGGCGCAAGATGGAAGATG
ACCCAAAAACGCCGAAACTGATCCTGACGGTGCGCAGCGGCGGCTACCAGTTCCTGCCCGAGACGACCTCCGAATGA

Upstream 100 bases:

>100_bases
TCCCTTGAAAAGCAAGGCACTGGCCAACATATGGCCCGAATTCTATCGTGTGGCTCACCTGCCAGGAATGACTTGGCCGG
CAATCGAGACAGGGCACCTC

Downstream 100 bases:

>100_bases
AACGTCTCCTGCCGCAGACCTTGCCTGCCTGGGTGCTGCTGATCGTCATTGCCGGCCTTCTGATCAGCCAGGTCGCGACC
CTCTATATCGTGTCGCGCGA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MKSDAHILIVDDDKGIRDLLQEFFQKRGLHTSVAADGTEMEAVLRRAQVDLIVLDVMLPGKSGLELCRDLRAQYSTPIIM
LTAVTETTDRVVGLEMGADDYVPKPFDPRELLARIRAVLRRNGAAEPKRATAKQIYRFAGWTMDCSRRRLTAPDDVRVEL
TMAEFNLLQTFVKSAQRVLTRDQLIELSGGDSDYSFDRSIDILVSRLRRKMEDDPKTPKLILTVRSGGYQFLPETTSE

Sequences:

>Translated_238_residues
MKSDAHILIVDDDKGIRDLLQEFFQKRGLHTSVAADGTEMEAVLRRAQVDLIVLDVMLPGKSGLELCRDLRAQYSTPIIM
LTAVTETTDRVVGLEMGADDYVPKPFDPRELLARIRAVLRRNGAAEPKRATAKQIYRFAGWTMDCSRRRLTAPDDVRVEL
TMAEFNLLQTFVKSAQRVLTRDQLIELSGGDSDYSFDRSIDILVSRLRRKMEDDPKTPKLILTVRSGGYQFLPETTSE
>Mature_238_residues
MKSDAHILIVDDDKGIRDLLQEFFQKRGLHTSVAADGTEMEAVLRRAQVDLIVLDVMLPGKSGLELCRDLRAQYSTPIIM
LTAVTETTDRVVGLEMGADDYVPKPFDPRELLARIRAVLRRNGAAEPKRATAKQIYRFAGWTMDCSRRRLTAPDDVRVEL
TMAEFNLLQTFVKSAQRVLTRDQLIELSGGDSDYSFDRSIDILVSRLRRKMEDDPKTPKLILTVRSGGYQFLPETTSE

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=238, Percent_Identity=42.8571428571429, Blast_Score=194, Evalue=6e-51,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=36.2445414847162, Blast_Score=171, Evalue=4e-44,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=37.6106194690265, Blast_Score=144, Evalue=3e-36,
Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=36.4035087719298, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=39.5555555555556, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=36.3247863247863, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=36, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=36.7256637168142, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=34.4978165938865, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=37.8854625550661, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=33.920704845815, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=33.1858407079646, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1789402, Length=232, Percent_Identity=32.3275862068966, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1790552, Length=228, Percent_Identity=30.7017543859649, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788550, Length=112, Percent_Identity=33.9285714285714, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790299, Length=124, Percent_Identity=30.6451612903226, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26933; Mature: 26933

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSDAHILIVDDDKGIRDLLQEFFQKRGLHTSVAADGTEMEAVLRRAQVDLIVLDVMLPG
CCCCCEEEEEECCCCHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHCEEEEEEECCC
KSGLELCRDLRAQYSTPIIMLTAVTETTDRVVGLEMGADDYVPKPFDPRELLARIRAVLR
CHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
RNGAAEPKRATAKQIYRFAGWTMDCSRRRLTAPDDVRVELTMAEFNLLQTFVKSAQRVLT
HCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
RDQLIELSGGDSDYSFDRSIDILVSRLRRKMEDDPKTPKLILTVRSGGYQFLPETTSE
HHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEECCCCCCC
>Mature Secondary Structure
MKSDAHILIVDDDKGIRDLLQEFFQKRGLHTSVAADGTEMEAVLRRAQVDLIVLDVMLPG
CCCCCEEEEEECCCCHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHCEEEEEEECCC
KSGLELCRDLRAQYSTPIIMLTAVTETTDRVVGLEMGADDYVPKPFDPRELLARIRAVLR
CHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
RNGAAEPKRATAKQIYRFAGWTMDCSRRRLTAPDDVRVELTMAEFNLLQTFVKSAQRVLT
HCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
RDQLIELSGGDSDYSFDRSIDILVSRLRRKMEDDPKTPKLILTVRSGGYQFLPETTSE
HHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]