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The map label for this gene is corA [H]

Identifier: 13472410

GI number: 13472410

Start: 2169596

End: 2170570

Strand: Direct

Name: corA [H]

Synonym: mlr2697

Alternate gene names: 13472410

Gene position: 2169596-2170570 (Clockwise)

Preceding gene: 13472409

Following gene: 13472411

Centisome position: 30.84

GC content: 62.05

Gene sequence:

>975_bases
ATGATCAAGGCATTTGTCGTGGACAATGATCGCCTGCGCGTCGTCGACGACCTGCTGGCCGACGCCGACAGGGTCGTCTG
GGCCGACCTGATCAGTCCGACCAAGGAAGAAGAGGCCACCATCGAGAGCTGGGTCGGCGTCGCCATCCCGACCCGCGAGG
AGATGGAGGAGATCGAGATTTCCAGCCGCCTCTACATCGAGGACGGCGCCTACTTCATGACCGCCACTTTGCCCGCGCAG
ACCGAGGTCGACGATCCCCTGATGTCGCCTGTCACCTTCGCGCTTGCCGGCAACAGGCTGATCACCATTCGCTATCATGA
ACCGAAGGCCTTCAAGACCTTCCCGCTGCGCGCCGAGAAGGTGGCGACCGGCTGCACCAGCGGCGACACCATCTTGATCG
GCCTCCTGGAAGCGATCGTCGACCGTCTCGCCGACATTCTCGAGCGCGCTGGCCGCGACATCGAGACGATTTCGCGCGAC
ATTTTCGAAGCGCGCTCGACCAAGGTGTCGAAGCGCAACCGCGACTTCCAGGAACTGTTGAAAGCCATCGGCCGCAAGGA
AGACATCGCCTCGTCCGTCCGCGACAGCCTGATCTCGCTGCAGCGCCTTGCTGGCTTCCTCGCCCATGTCGCGACCCTGA
CCAAGATGAGCAAGGATGTCCGCGCCCGCATCAAGACCTTGTCGCGCGACGTGCTGTCGCTCGCCGACCATGCCACCTTC
CTGTCGCAGAAGATCTCCTTCCTGCTCGACGCCACGCTCGGCATGATCTCGATCGAGCAGAACGCCATCATCAAGATCTT
CTCGGTCGCCGCCGTCATCTTCCTGCCGCCGACACTGGTCGCCTCGATCTACGGCATGAATTTCACCGTCATTCCCGAGC
TGAAATGGGAGCTTGGCTATCCCTTCGCCATAGGCCTGATGATCCTGTCGGCGATCCTGCCCTTCTGGTATTTCCGCCGC
CGCGGCTGGCTCTGA

Upstream 100 bases:

>100_bases
CGGGTCTAAGCGGCTGGCACACGGTCGCGCACACGACGAAGAGCCGTGCAATCCGACACGACGCGCAATCCGAACGCACC
TTCGCAGGGGAGATCTGGCG

Downstream 100 bases:

>100_bases
CCGCTGCCGCCGGCGCCGGCTGCCTCAGGCTGGCTCACCAGAAAGGACTTGACCAAATCGCCCCTGGCCTGCATCCGGGT
CTGCCGATCCGCGCGGGTCG

Product: magnesium/cobalt transport protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MIKAFVVDNDRLRVVDDLLADADRVVWADLISPTKEEEATIESWVGVAIPTREEMEEIEISSRLYIEDGAYFMTATLPAQ
TEVDDPLMSPVTFALAGNRLITIRYHEPKAFKTFPLRAEKVATGCTSGDTILIGLLEAIVDRLADILERAGRDIETISRD
IFEARSTKVSKRNRDFQELLKAIGRKEDIASSVRDSLISLQRLAGFLAHVATLTKMSKDVRARIKTLSRDVLSLADHATF
LSQKISFLLDATLGMISIEQNAIIKIFSVAAVIFLPPTLVASIYGMNFTVIPELKWELGYPFAIGLMILSAILPFWYFRR
RGWL

Sequences:

>Translated_324_residues
MIKAFVVDNDRLRVVDDLLADADRVVWADLISPTKEEEATIESWVGVAIPTREEMEEIEISSRLYIEDGAYFMTATLPAQ
TEVDDPLMSPVTFALAGNRLITIRYHEPKAFKTFPLRAEKVATGCTSGDTILIGLLEAIVDRLADILERAGRDIETISRD
IFEARSTKVSKRNRDFQELLKAIGRKEDIASSVRDSLISLQRLAGFLAHVATLTKMSKDVRARIKTLSRDVLSLADHATF
LSQKISFLLDATLGMISIEQNAIIKIFSVAAVIFLPPTLVASIYGMNFTVIPELKWELGYPFAIGLMILSAILPFWYFRR
RGWL
>Mature_324_residues
MIKAFVVDNDRLRVVDDLLADADRVVWADLISPTKEEEATIESWVGVAIPTREEMEEIEISSRLYIEDGAYFMTATLPAQ
TEVDDPLMSPVTFALAGNRLITIRYHEPKAFKTFPLRAEKVATGCTSGDTILIGLLEAIVDRLADILERAGRDIETISRD
IFEARSTKVSKRNRDFQELLKAIGRKEDIASSVRDSLISLQRLAGFLAHVATLTKMSKDVRARIKTLSRDVLSLADHATF
LSQKISFLLDATLGMISIEQNAIIKIFSVAAVIFLPPTLVASIYGMNFTVIPELKWELGYPFAIGLMILSAILPFWYFRR
RGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=325, Percent_Identity=37.5384615384615, Blast_Score=210, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 36341; Mature: 36341

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKAFVVDNDRLRVVDDLLADADRVVWADLISPTKEEEATIESWVGVAIPTREEMEEIEI
CEEEEEECCCCHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHH
SSRLYIEDGAYFMTATLPAQTEVDDPLMSPVTFALAGNRLITIRYHEPKAFKTFPLRAEK
CCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHEEECCEEEEEEEECCCCCEECCCCHHH
VATGCTSGDTILIGLLEAIVDRLADILERAGRDIETISRDIFEARSTKVSKRNRDFQELL
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
KAIGRKEDIASSVRDSLISLQRLAGFLAHVATLTKMSKDVRARIKTLSRDVLSLADHATF
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSQKISFLLDATLGMISIEQNAIIKIFSVAAVIFLPPTLVASIYGMNFTVIPELKWELGY
HHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCHHCCCC
PFAIGLMILSAILPFWYFRRRGWL
HHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIKAFVVDNDRLRVVDDLLADADRVVWADLISPTKEEEATIESWVGVAIPTREEMEEIEI
CEEEEEECCCCHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHH
SSRLYIEDGAYFMTATLPAQTEVDDPLMSPVTFALAGNRLITIRYHEPKAFKTFPLRAEK
CCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHEEECCEEEEEEEECCCCCEECCCCHHH
VATGCTSGDTILIGLLEAIVDRLADILERAGRDIETISRDIFEARSTKVSKRNRDFQELL
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
KAIGRKEDIASSVRDSLISLQRLAGFLAHVATLTKMSKDVRARIKTLSRDVLSLADHATF
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSQKISFLLDATLGMISIEQNAIIKIFSVAAVIFLPPTLVASIYGMNFTVIPELKWELGY
HHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCHHCCCC
PFAIGLMILSAILPFWYFRRRGWL
HHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]