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The map label for this gene is lgt

Identifier: 13472395

GI number: 13472395

Start: 2154775

End: 2155635

Strand: Direct

Name: lgt

Synonym: mlr2678

Alternate gene names: 13472395

Gene position: 2154775-2155635 (Clockwise)

Preceding gene: 13472394

Following gene: 13472396

Centisome position: 30.62

GC content: 63.76

Gene sequence:

>861_bases
TTGAACGAATATTTCCTGCTGCCGCTGGCCTCGCTGCCCTTCCCCAACATCAACCCGATCCTCATCCAGATCGGGCCGCT
GGCGGTGCACTGGTACGGCGTCGGCTACATCGTCGGCATCCTGTTTGCCTGGTGGTATGCCAAGCGGCTTGCCGCCAACC
CGAAGCTGTGGCCCGACGGCATCCTGCCAATGAAGCTGGAGGACCTCGACGATTTCATTGTCTGGGCGGCCATCGGCGTC
GTGCTCGGCGGCCGCACCGGCTATGTGCTGTTCTATGATCTGCCGCGCTACATCGCGCATCCGCTCGACATCTTCGCCGT
CTGGCAAGGCGGCATGTCGTTCCATGGCGGCCTGCTTGGGGTCATCCTTGCCATGACGCTGTTTTCCATCAAGCGCGGTA
TACGCACCTGGTCGCTGTTCGATGTCGTGGCCGCCGGCGTGCCGGTTGGGCTCGGCCTGGTGCGCGTCGCCAACTTCATC
AATTCCGAGCTCTGGGGCCGGCCGACGGACGTACCCTGGGCAATAGAATTCCCCAATGGCGGACCGTTTACCCGCCATCC
GAGCCAGCTCTACGAGGCCTTGCTCGAAGGCCTGGTGCTGTTTGTCGTGCTGCGCATCCTCACCCATTCGCGCCTCAAAC
TGAAGACGCCGCGCTTCGTCGGCGGCGCTTTCATCTGCGGCTACGGCCTGTCGCGCATCTTCGTCGAGTTCTTCCGCGAG
CCCGACCAGCAGCTCGGCTACCTCCTCGGCACCAACTGGCTGACCATGGGCATGATCCTGTCGACGCCGATGGTGCTGGC
CGGCATCTGGGCGATGGCGACGGCCAAGCCGGTGAAGCAAGCGCAGCCGCAGGCGACATGA

Upstream 100 bases:

>100_bases
GATCCGTCGCGACGCTTGACGGCGGCCGGCTTGCCTTGACCCTGCCAAAACCCTGCCGCATGGTCCGCGCCCGAATGCGA
CCGCAACCGAGAGCTCCCCG

Downstream 100 bases:

>100_bases
CGCGGCTGAAGACCCGAATCGTCGATCTGATCGATGCGCTGGGCCCCCTTCCCGTCAACGAATACATGGCGATGTGCCTG
TTCGACCCCGCGGACGGCTA

Product: prolipoprotein diacylglyceryl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MNEYFLLPLASLPFPNINPILIQIGPLAVHWYGVGYIVGILFAWWYAKRLAANPKLWPDGILPMKLEDLDDFIVWAAIGV
VLGGRTGYVLFYDLPRYIAHPLDIFAVWQGGMSFHGGLLGVILAMTLFSIKRGIRTWSLFDVVAAGVPVGLGLVRVANFI
NSELWGRPTDVPWAIEFPNGGPFTRHPSQLYEALLEGLVLFVVLRILTHSRLKLKTPRFVGGAFICGYGLSRIFVEFFRE
PDQQLGYLLGTNWLTMGMILSTPMVLAGIWAMATAKPVKQAQPQAT

Sequences:

>Translated_286_residues
MNEYFLLPLASLPFPNINPILIQIGPLAVHWYGVGYIVGILFAWWYAKRLAANPKLWPDGILPMKLEDLDDFIVWAAIGV
VLGGRTGYVLFYDLPRYIAHPLDIFAVWQGGMSFHGGLLGVILAMTLFSIKRGIRTWSLFDVVAAGVPVGLGLVRVANFI
NSELWGRPTDVPWAIEFPNGGPFTRHPSQLYEALLEGLVLFVVLRILTHSRLKLKTPRFVGGAFICGYGLSRIFVEFFRE
PDQQLGYLLGTNWLTMGMILSTPMVLAGIWAMATAKPVKQAQPQAT
>Mature_286_residues
MNEYFLLPLASLPFPNINPILIQIGPLAVHWYGVGYIVGILFAWWYAKRLAANPKLWPDGILPMKLEDLDDFIVWAAIGV
VLGGRTGYVLFYDLPRYIAHPLDIFAVWQGGMSFHGGLLGVILAMTLFSIKRGIRTWSLFDVVAAGVPVGLGLVRVANFI
NSELWGRPTDVPWAIEFPNGGPFTRHPSQLYEALLEGLVLFVVLRILTHSRLKLKTPRFVGGAFICGYGLSRIFVEFFRE
PDQQLGYLLGTNWLTMGMILSTPMVLAGIWAMATAKPVKQAQPQAT

Specific function: Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins

COG id: COG0682

COG function: function code M; Prolipoprotein diacylglyceryltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lgt family

Homologues:

Organism=Escherichia coli, GI1789192, Length=292, Percent_Identity=42.1232876712329, Blast_Score=207, Evalue=8e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LGT_RHILO (Q98HW8)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_103962.1
- GeneID:   1226623
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr2678
- NMPDR:   fig|266835.1.peg.2066
- HOGENOM:   HBG450278
- OMA:   NGELYGK
- ProtClustDB:   PRK00052
- HAMAP:   MF_01147
- InterPro:   IPR001640
- TIGRFAMs:   TIGR00544

Pfam domain/function: PF01790 LGT

EC number: 2.4.99.- [C]

Molecular weight: Translated: 31814; Mature: 31814

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS01311 LGT

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xebc1010)-; HASH(0x114cc5a8)-; HASH(0x114cc38c)-; HASH(0x40b370f0)-; HASH(0x110d247c)-; HASH(0x40ba8208)-; HASH(0x11086a34)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEYFLLPLASLPFPNINPILIQIGPLAVHWYGVGYIVGILFAWWYAKRLAANPKLWPDG
CCCEEEEEECCCCCCCCCEEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ILPMKLEDLDDFIVWAAIGVVLGGRTGYVLFYDLPRYIAHPLDIFAVWQGGMSFHGGLLG
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHCHHHHHHHHHCCCCCCHHHHH
VILAMTLFSIKRGIRTWSLFDVVAAGVPVGLGLVRVANFINSELWGRPTDVPWAIEFPNG
HHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCC
GPFTRHPSQLYEALLEGLVLFVVLRILTHSRLKLKTPRFVGGAFICGYGLSRIFVEFFRE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHCHHHHHHHHHHHHHHHHHHC
PDQQLGYLLGTNWLTMGMILSTPMVLAGIWAMATAKPVKQAQPQAT
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCH
>Mature Secondary Structure
MNEYFLLPLASLPFPNINPILIQIGPLAVHWYGVGYIVGILFAWWYAKRLAANPKLWPDG
CCCEEEEEECCCCCCCCCEEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ILPMKLEDLDDFIVWAAIGVVLGGRTGYVLFYDLPRYIAHPLDIFAVWQGGMSFHGGLLG
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHCHHHHHHHHHCCCCCCHHHHH
VILAMTLFSIKRGIRTWSLFDVVAAGVPVGLGLVRVANFINSELWGRPTDVPWAIEFPNG
HHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCC
GPFTRHPSQLYEALLEGLVLFVVLRILTHSRLKLKTPRFVGGAFICGYGLSRIFVEFFRE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHCHHHHHHHHHHHHHHHHHHC
PDQQLGYLLGTNWLTMGMILSTPMVLAGIWAMATAKPVKQAQPQAT
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11214968