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The map label for this gene is emrK [H]

Identifier: 13472330

GI number: 13472330

Start: 2096321

End: 2097424

Strand: Reverse

Name: emrK [H]

Synonym: mll2590

Alternate gene names: 13472330

Gene position: 2097424-2096321 (Counterclockwise)

Preceding gene: 13472331

Following gene: 13472329

Centisome position: 29.81

GC content: 66.58

Gene sequence:

>1104_bases
ATGAACAAGGTTCTCTCCGCCGCCGAGTTGCAGCCGGCGCAGCCATCCGCCGTCCAGATACCCGCGCCCGCCAAAAGCCG
CCGCAAGCCGATCGTCATGCTGGGCGCCGCGATCGCCATCGGCGTCGCCGGCTGGTATGGCTTTCAGTGGTGGCAGGCAG
GCCGGTTCGTGATGTCGACCGACGATGCCTATGTCGGCGGCAATGTCACGCCGCTGGCGCCACGCGTCGCCGGGCATATC
GATCAGATCCTCGTCGAGGACAATCAGCATGTCGACGCCGGCCAGCTCATCATCCGCATCGACGACCGGCCGTTCAAGGC
GGCGGTGGAGCGTGCGCGGGCTTCCGTCCAGCAGCAGCAATCGGCGCTCGACAATCTTCGCGCCCAGGTCTCGCTGCAGA
ATTCGCTGATCGAACAGGCAGAGGCCGATCTCGAGGCGAAGAGTGCAGCCGCCACATTTACTACACAGGATGCCAAGCGC
TACGAGGTGCTGGCCAGCACCAGGGCCGGCTCGCAGCAGGACGCGCAGAGAAGCCTTGCCGCCGACGGGCAGGCGAAGGC
TTCCGTTTCCGCCTCGCGTGCCGGGCTTGCGGCCGCCAGGCAACAGCTCGACGTGCTGAACACGCAGATCTCGGAAGCGA
CCGCCGCGGTTCTGGCCGCCAAGGCCGATCTCGACACGGCTGAGCTCGATCTTGGCTTCACGCAGATCCGCGCTCCGATC
GACGGCCTCGTCGGCAACCGGCTGGCGCAGGTCGGCACCTATGTCTCGCCGGGCAGCTATCTGCTGACGATCGTCCCGCA
GAGCGGGCTGTGGGTCGATGCCAATTTCAAGGAAGATCAGTTGCGGCGCATGGCGGACGGACAGGCGGCGACGGTCTATA
CCGACATCGCGCCCGACCAGCCGCTCAAGGGCCATGTCAGCAGCCTGGGACCGGCGACGGGGGCGATCTTCAGCGTCATC
CCGGCGCAGAACGCCACCGGCAATTTCACCAAGATCGTCCAGCGTGTTCCTGTCCGCATCACCATCGACCCGGACCAGGC
GCGGAAGGTCGCGCTGCGGCCAGGCCTCTCCACCGTCGTGACCGTCGATACCGGCGCGCACTGA

Upstream 100 bases:

>100_bases
CCACCGACCGCATGCGGCAGCGCTATCGCTTCAGCACAGAGGGTTCTGGCCTGCCGCTCATCGACAACGTTGATCAAAGC
CGTGAAGAGGCGCGGGGCAA

Downstream 100 bases:

>100_bases
GGGCATCATGTCGGAGCGCCCGCAATCCTTCTTCTCCAGCATCCTGCCGTTCATGGTGATGTGCGTGGGGATGTTCATCG
CGCTGCTCGACATCCAGATC

Product: secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MNKVLSAAELQPAQPSAVQIPAPAKSRRKPIVMLGAAIAIGVAGWYGFQWWQAGRFVMSTDDAYVGGNVTPLAPRVAGHI
DQILVEDNQHVDAGQLIIRIDDRPFKAAVERARASVQQQQSALDNLRAQVSLQNSLIEQAEADLEAKSAAATFTTQDAKR
YEVLASTRAGSQQDAQRSLAADGQAKASVSASRAGLAAARQQLDVLNTQISEATAAVLAAKADLDTAELDLGFTQIRAPI
DGLVGNRLAQVGTYVSPGSYLLTIVPQSGLWVDANFKEDQLRRMADGQAATVYTDIAPDQPLKGHVSSLGPATGAIFSVI
PAQNATGNFTKIVQRVPVRITIDPDQARKVALRPGLSTVVTVDTGAH

Sequences:

>Translated_367_residues
MNKVLSAAELQPAQPSAVQIPAPAKSRRKPIVMLGAAIAIGVAGWYGFQWWQAGRFVMSTDDAYVGGNVTPLAPRVAGHI
DQILVEDNQHVDAGQLIIRIDDRPFKAAVERARASVQQQQSALDNLRAQVSLQNSLIEQAEADLEAKSAAATFTTQDAKR
YEVLASTRAGSQQDAQRSLAADGQAKASVSASRAGLAAARQQLDVLNTQISEATAAVLAAKADLDTAELDLGFTQIRAPI
DGLVGNRLAQVGTYVSPGSYLLTIVPQSGLWVDANFKEDQLRRMADGQAATVYTDIAPDQPLKGHVSSLGPATGAIFSVI
PAQNATGNFTKIVQRVPVRITIDPDQARKVALRPGLSTVVTVDTGAH
>Mature_367_residues
MNKVLSAAELQPAQPSAVQIPAPAKSRRKPIVMLGAAIAIGVAGWYGFQWWQAGRFVMSTDDAYVGGNVTPLAPRVAGHI
DQILVEDNQHVDAGQLIIRIDDRPFKAAVERARASVQQQQSALDNLRAQVSLQNSLIEQAEADLEAKSAAATFTTQDAKR
YEVLASTRAGSQQDAQRSLAADGQAKASVSASRAGLAAARQQLDVLNTQISEATAAVLAAKADLDTAELDLGFTQIRAPI
DGLVGNRLAQVGTYVSPGSYLLTIVPQSGLWVDANFKEDQLRRMADGQAATVYTDIAPDQPLKGHVSSLGPATGAIFSVI
PAQNATGNFTKIVQRVPVRITIDPDQARKVALRPGLSTVVTVDTGAH

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=348, Percent_Identity=33.0459770114943, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1789041, Length=368, Percent_Identity=33.4239130434783, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1790519, Length=296, Percent_Identity=29.3918918918919, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI87081951, Length=303, Percent_Identity=27.3927392739274, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789637, Length=312, Percent_Identity=27.2435897435897, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790024, Length=251, Percent_Identity=26.2948207171315, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787013, Length=346, Percent_Identity=27.1676300578035, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1789900, Length=298, Percent_Identity=27.5167785234899, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790012, Length=246, Percent_Identity=25.609756097561, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 38843; Mature: 38843

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVLSAAELQPAQPSAVQIPAPAKSRRKPIVMLGAAIAIGVAGWYGFQWWQAGRFVMST
CCCCCCCHHCCCCCCCEEECCCCCHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCEEEEEC
DDAYVGGNVTPLAPRVAGHIDQILVEDNQHVDAGQLIIRIDDRPFKAAVERARASVQQQQ
CCEEECCCCCCCCHHHHHHHHHHEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
SALDNLRAQVSLQNSLIEQAEADLEAKSAAATFTTQDAKRYEVLASTRAGSQQDAQRSLA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEECCCCHHHHHHHHCCCCCHHHHHHHHH
ADGQAKASVSASRAGLAAARQQLDVLNTQISEATAAVLAAKADLDTAELDLGFTQIRAPI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHCCH
DGLVGNRLAQVGTYVSPGSYLLTIVPQSGLWVDANFKEDQLRRMADGQAATVYTDIAPDQ
HHHHHHHHHHHCCEECCCCEEEEEECCCCEEEECCCCHHHHHHHHCCCEEEEEEECCCCC
PLKGHVSSLGPATGAIFSVIPAQNATGNFTKIVQRVPVRITIDPDQARKVALRPGLSTVV
CCCCHHHHCCCHHHHHEEEECCCCCCCHHHHHHHHCCEEEEECCCHHHEEEECCCCCEEE
TVDTGAH
EECCCCC
>Mature Secondary Structure
MNKVLSAAELQPAQPSAVQIPAPAKSRRKPIVMLGAAIAIGVAGWYGFQWWQAGRFVMST
CCCCCCCHHCCCCCCCEEECCCCCHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCEEEEEC
DDAYVGGNVTPLAPRVAGHIDQILVEDNQHVDAGQLIIRIDDRPFKAAVERARASVQQQQ
CCEEECCCCCCCCHHHHHHHHHHEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
SALDNLRAQVSLQNSLIEQAEADLEAKSAAATFTTQDAKRYEVLASTRAGSQQDAQRSLA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEECCCCHHHHHHHHCCCCCHHHHHHHHH
ADGQAKASVSASRAGLAAARQQLDVLNTQISEATAAVLAAKADLDTAELDLGFTQIRAPI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHCCH
DGLVGNRLAQVGTYVSPGSYLLTIVPQSGLWVDANFKEDQLRRMADGQAATVYTDIAPDQ
HHHHHHHHHHHCCEECCCCEEEEEECCCCEEEECCCCHHHHHHHHCCCEEEEEEECCCCC
PLKGHVSSLGPATGAIFSVIPAQNATGNFTKIVQRVPVRITIDPDQARKVALRPGLSTVV
CCCCHHHHCCCHHHHHEEEECCCCCCCHHHHHHHHCCEEEEECCCHHHEEEECCCCCEEE
TVDTGAH
EECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]