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The map label for this gene is mntR [H]

Identifier: 13472263

GI number: 13472263

Start: 2029374

End: 2029826

Strand: Reverse

Name: mntR [H]

Synonym: mll2499

Alternate gene names: 13472263

Gene position: 2029826-2029374 (Counterclockwise)

Preceding gene: 13472267

Following gene: 13472261

Centisome position: 28.85

GC content: 66.0

Gene sequence:

>453_bases
TTGGCGCTGAAGAACAGATCTGTCCCGCGTGAGCCATTGCCCGACGCCGATGTCCATTCGGAAGGCTTCCGGCAGCAGCG
CCAAGCGCGCCGCAGCGCGCTGGTCGAAGATTATGTCGAGCTGATCGCCGATTTGATCGAGGACGGCAACGAGGCGCGCC
AGGTCGACATTGCCGCTCGTCTCGGCGTCGCGCAGCCGACAGTGGCCAAGATGCTGACGCGCCTTTGCGCCGACGGGCTG
GTGTCGAGAAAACCCTATCGCGGCGTGTTCCTGACCGAAGCCGGCCGCAAGGTCGCGGAGGAAAGCCGCATCCGCCACCA
GACGGTGGAAGCCTTCCTGCGCTCGCTCGGCGTCAGCGCCGAAACCGCGCGCATCGATGCCGAGGGCATCGAGCATCATG
TCAGCGCCGAGACGCTGGAGGCTTTTCGCAAGGCGATGACGGCGCCGCGCTAG

Upstream 100 bases:

>100_bases
ACGCCGGTTGCACCTGTGGGGGAATGCAAATAAACGGCCTGAAGAATCAGAGCCCGTGCTATAAAGCAGGAACGGCTAAA
CTCCCGAGGAGGAGCGCGCA

Downstream 100 bases:

>100_bases
GGTCAGACCCAATCGTTCTAATGACCGTTCGAACGAGGTTGTGCGAAAACGCGATTGCGCCCGTCGTTGGGGACGATGGG
TTCGCAACCGCGGGCTAGCG

Product: manganese transport regulator MntR

Products: NA

Alternate protein names: Manganese transport regulator [H]

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MALKNRSVPREPLPDADVHSEGFRQQRQARRSALVEDYVELIADLIEDGNEARQVDIAARLGVAQPTVAKMLTRLCADGL
VSRKPYRGVFLTEAGRKVAEESRIRHQTVEAFLRSLGVSAETARIDAEGIEHHVSAETLEAFRKAMTAPR

Sequences:

>Translated_150_residues
MALKNRSVPREPLPDADVHSEGFRQQRQARRSALVEDYVELIADLIEDGNEARQVDIAARLGVAQPTVAKMLTRLCADGL
VSRKPYRGVFLTEAGRKVAEESRIRHQTVEAFLRSLGVSAETARIDAEGIEHHVSAETLEAFRKAMTAPR
>Mature_149_residues
ALKNRSVPREPLPDADVHSEGFRQQRQARRSALVEDYVELIADLIEDGNEARQVDIAARLGVAQPTVAKMLTRLCADGLV
SRKPYRGVFLTEAGRKVAEESRIRHQTVEAFLRSLGVSAETARIDAEGIEHHVSAETLEAFRKAMTAPR

Specific function: In the presence of manganese, it represses the manganese transporter mntH [H]

COG id: COG1321

COG function: function code K; Mn-dependent transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH dtxR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787038, Length=131, Percent_Identity=65.6488549618321, Blast_Score=169, Evalue=8e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001367
- InterPro:   IPR022689
- InterPro:   IPR022687
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02742 Fe_dep_repr_C; PF01325 Fe_dep_repress [H]

EC number: NA

Molecular weight: Translated: 16660; Mature: 16529

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS50944 HTH_DTXR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALKNRSVPREPLPDADVHSEGFRQQRQARRSALVEDYVELIADLIEDGNEARQVDIAAR
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LGVAQPTVAKMLTRLCADGLVSRKPYRGVFLTEAGRKVAEESRIRHQTVEAFLRSLGVSA
HCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ETARIDAEGIEHHVSAETLEAFRKAMTAPR
HHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ALKNRSVPREPLPDADVHSEGFRQQRQARRSALVEDYVELIADLIEDGNEARQVDIAAR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LGVAQPTVAKMLTRLCADGLVSRKPYRGVFLTEAGRKVAEESRIRHQTVEAFLRSLGVSA
HCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ETARIDAEGIEHHVSAETLEAFRKAMTAPR
HHHHCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]