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The map label for this gene is dgdR [H]

Identifier: 13472267

GI number: 13472267

Start: 2033148

End: 2034047

Strand: Reverse

Name: dgdR [H]

Synonym: mll2505

Alternate gene names: 13472267

Gene position: 2034047-2033148 (Counterclockwise)

Preceding gene: 13472269

Following gene: 13472263

Centisome position: 28.91

GC content: 68.0

Gene sequence:

>900_bases
ATGCTTGGCATTAGCATCTATAATGGCGACATGATCCGCAATCTCGATACGGCGCTGATGCGCACCTTCGTCATGGTCGC
CGACAAGGCCAGCATGACGGCGGCGGCCAATGCGCTGCACCTGACCCAAGGCGCCGTCAGCCAGCAGGTCAAGCGGCTGG
AACAGACGCTCGGCTGCGTCCTGTTCGAGCGCGACCGGCGCGGCCTGCGCCTGACGCGATCCGGCGAGCGGCTGTTCGAC
AAGGCCAAGCGCCTGCTCAGCCTCAATGACGAGATCTGGGCCGAGATGGCGGGCTCGGCCGTCGCCGGCCAGGTGCGGCT
CGGCGTGCCCTATGATCTGGTCGGCACGCTGCTGGCGCCGGTGCTCAAGGCCTATGCCGAGACCTATCCGCAGGTCGAGA
TCTCGCTGGTCTGCGCGTCATCGCCGGAACTGGCGTCAGCACTAGCGGCCGGAACCATCGACCTCGCGGTGATCGAGGAA
CGGGTCGGCCCGACATCGGGCGAATGCCTGGCCATCGACCGGCTGGTCTGGGTCGGCGCCAGAGGCGGCGTTGCCCGCGC
CAAGCGGCCGCTGCCGGTGTCGATCGTCGCCGACACCTGCGCCTTTCGCCCTGTCGTGCTTGCGGCGCTCAACGAGCATG
GGCTGGAGTGGCGCACCGTGTTCGAGAACGGCAACATCGACGCCACGACGGCGACCGTGCGCTCCGACCTCGCCGTCACC
ACCTGGCTGGCCTCCACCGTGCCGGCCGATCTCGACATCTTGCCGTTCGATGTCGGTCTGCCGCCACTGCCGAATTTTGC
CATCAATCTGCATCTGCCGCGGCACGGCGTCGGCCCGGCCGCGCAGGAATTCGCGCGGCATATCAGGGATGGGCTGGCGC
GGCGACCGGCGGCGGCTTGA

Upstream 100 bases:

>100_bases
GCAAACAGGATGAGCGGCAGGATAGGCTGGAGCATCGGGCGTCCTACGTCGAAGGCTCCATAGTAGGCTTGACCTGGCAT
CAGTAAATGCAATGTTTGCG

Downstream 100 bases:

>100_bases
GACCAAGCGGAACTTGGGTTCCTCCCTCCGGAGGGAGAGGAAAGGTAACCAAGGCCGTCCGCTACTTCCAGTTCCTGCGC
CGCTCCAGCTCGGCGACGGA

Product: transcriptional regulator

Products: NA

Alternate protein names: 2,2-dialkylglycine decarboxylase repressor [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MLGISIYNGDMIRNLDTALMRTFVMVADKASMTAAANALHLTQGAVSQQVKRLEQTLGCVLFERDRRGLRLTRSGERLFD
KAKRLLSLNDEIWAEMAGSAVAGQVRLGVPYDLVGTLLAPVLKAYAETYPQVEISLVCASSPELASALAAGTIDLAVIEE
RVGPTSGECLAIDRLVWVGARGGVARAKRPLPVSIVADTCAFRPVVLAALNEHGLEWRTVFENGNIDATTATVRSDLAVT
TWLASTVPADLDILPFDVGLPPLPNFAINLHLPRHGVGPAAQEFARHIRDGLARRPAAA

Sequences:

>Translated_299_residues
MLGISIYNGDMIRNLDTALMRTFVMVADKASMTAAANALHLTQGAVSQQVKRLEQTLGCVLFERDRRGLRLTRSGERLFD
KAKRLLSLNDEIWAEMAGSAVAGQVRLGVPYDLVGTLLAPVLKAYAETYPQVEISLVCASSPELASALAAGTIDLAVIEE
RVGPTSGECLAIDRLVWVGARGGVARAKRPLPVSIVADTCAFRPVVLAALNEHGLEWRTVFENGNIDATTATVRSDLAVT
TWLASTVPADLDILPFDVGLPPLPNFAINLHLPRHGVGPAAQEFARHIRDGLARRPAAA
>Mature_299_residues
MLGISIYNGDMIRNLDTALMRTFVMVADKASMTAAANALHLTQGAVSQQVKRLEQTLGCVLFERDRRGLRLTRSGERLFD
KAKRLLSLNDEIWAEMAGSAVAGQVRLGVPYDLVGTLLAPVLKAYAETYPQVEISLVCASSPELASALAAGTIDLAVIEE
RVGPTSGECLAIDRLVWVGARGGVARAKRPLPVSIVADTCAFRPVVLAALNEHGLEWRTVFENGNIDATTATVRSDLAVT
TWLASTVPADLDILPFDVGLPPLPNFAINLHLPRHGVGPAAQEFARHIRDGLARRPAAA

Specific function: Not Known, Does Not Seem To Act On The Proton Translocating NADH Dehydrogenase Genes (Nuoa-N) Which Are Part Of The Lrha Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=254, Percent_Identity=33.4645669291339, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1788297, Length=236, Percent_Identity=30.0847457627119, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789204, Length=292, Percent_Identity=25.6849315068493, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI145693193, Length=125, Percent_Identity=30.4, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787879, Length=168, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI157672245, Length=140, Percent_Identity=32.8571428571429, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790208, Length=145, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790262, Length=238, Percent_Identity=26.890756302521, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787601, Length=154, Percent_Identity=26.6233766233766, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI145693105, Length=149, Percent_Identity=26.1744966442953, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790399, Length=150, Percent_Identity=28, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786401, Length=137, Percent_Identity=33.5766423357664, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI48994962, Length=149, Percent_Identity=30.2013422818792, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787806, Length=160, Percent_Identity=25, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI2367136, Length=135, Percent_Identity=31.8518518518519, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081904, Length=146, Percent_Identity=31.5068493150685, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787589, Length=151, Percent_Identity=29.1390728476821, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32050; Mature: 32050

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGISIYNGDMIRNLDTALMRTFVMVADKASMTAAANALHLTQGAVSQQVKRLEQTLGCV
CEEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LFERDRRGLRLTRSGERLFDKAKRLLSLNDEIWAEMAGSAVAGQVRLGVPYDLVGTLLAP
EEECCCCCCEEECCHHHHHHHHHHHHCCCHHHHHHHCCCCEECEEEECCCHHHHHHHHHH
VLKAYAETYPQVEISLVCASSPELASALAAGTIDLAVIEERVGPTSGECLAIDRLVWVGA
HHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEEEEEECC
RGGVARAKRPLPVSIVADTCAFRPVVLAALNEHGLEWRTVFENGNIDATTATVRSDLAVT
CCCHHHCCCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEHHHHHHCHHHH
TWLASTVPADLDILPFDVGLPPLPNFAINLHLPRHGVGPAAQEFARHIRDGLARRPAAA
HHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLGISIYNGDMIRNLDTALMRTFVMVADKASMTAAANALHLTQGAVSQQVKRLEQTLGCV
CEEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LFERDRRGLRLTRSGERLFDKAKRLLSLNDEIWAEMAGSAVAGQVRLGVPYDLVGTLLAP
EEECCCCCCEEECCHHHHHHHHHHHHCCCHHHHHHHCCCCEECEEEECCCHHHHHHHHHH
VLKAYAETYPQVEISLVCASSPELASALAAGTIDLAVIEERVGPTSGECLAIDRLVWVGA
HHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEEEEEECC
RGGVARAKRPLPVSIVADTCAFRPVVLAALNEHGLEWRTVFENGNIDATTATVRSDLAVT
CCCHHHCCCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEHHHHHHCHHHH
TWLASTVPADLDILPFDVGLPPLPNFAINLHLPRHGVGPAAQEFARHIRDGLARRPAAA
HHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180928 [H]