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The map label for this gene is mocR [H]

Identifier: 13472215

GI number: 13472215

Start: 1979957

End: 1981411

Strand: Reverse

Name: mocR [H]

Synonym: mll2434

Alternate gene names: 13472215

Gene position: 1981411-1979957 (Counterclockwise)

Preceding gene: 13472218

Following gene: 13472213

Centisome position: 28.16

GC content: 64.4

Gene sequence:

>1455_bases
ATGAAGACCAGCTTTCCCGTCGACGGCATCGCCCTGGATCGCGACAGCCCCGCCAATCTGCACCGGCAGCTCTATGTCCA
GTTGCGCGGCCTGATCGAACGGCGCGTGCTGCCGAGCGGCCACGCACTGCCCTCGACACGGGTCATGGCGCGGGATCTGA
ATGTCGGGCGCAACACGGTGATTGCCGCTTGCGACCAGCTGGCGCTGGAGGGCTATCTGGCGATACGTCCGCGCAGGCCG
TCAGTGGTGATGGACCTGCCGACGCGTTCGGCAGTTGCCGAACAAATGTCGGTCGAGGACGCCAATCCGCTGTCGCGGCG
CGGCCAGACCATGCTTGCCCAACCCTATCATCATGGCCGGCCGGGCATGCTTGCCTTCCATCCCGGCATGCCGGATCCGG
ACAATTTTCCGTTCAACACCTGGTCGAAGCTGCTCGGCCGCCGCGCCAAGTTCGCCCATATCGATCTTTTCGGCACCTAT
CACGTCAAGGGCTATCCGCCGCTTTGCGAGGCCATAGCGCGCTACCTCACCGCCTCGCGCGGCGTGAAGTGCACAGCCGA
GCAGATCGTGGTGACCAATGGCGCGCAGTCGGCGTTCGATCTCCTGGCCCGGCTGCTGATCGATGACGGCGACACGGTGT
GGATGGAGGAGCCTGGCTATTACGGCGCCGGCTCGGCCTTCGTCTCGGCCGGGGCGAAACTGGCGCCGCTGCGCGTCAGC
AATGCCGGCTGGGATCTCGATCCGCCTGATGTCGTGCCCCGCATGATCTTCGTGACGCCCTCCTGCCATCACCCGCTCGG
CATAACCATGCCGATGGAACAGCGGCTCAACCTGCTGCACATGGCCGAGACCTGGCGCTCGTGGATCATCGAGGACGACT
ATGACGGCGAATACCGTTTCCAGGGCCAGCCCATCCCGGCGCTGCAAGGCATAGGCGCGTCGAACCGCGTGGTCTATGTC
GGCACTTTCGCCAAGATCCTTTTCCCGGCCATGCGTCTCGGCTTCATGGTGGCGCCCAAGGCGATCGACCATACGATCGT
CTCGGCGCTGAGCGTGAGCGGCCAGTTCGCCCCCTTGCTGACCCAGGCTGCGCTGGCGGACTTCATGAATGAGGGGCATT
TCACCCGCCATCTCAGGCGCATGCGGCGGCTCTACGCGGAGAGACGGCAGTTCTTCCTGGAAAGCGCGCAACGGCATCTC
GGGGAATGGCTGGATTTCCACGCGACCGAATCCGGCATCCAGGTCGTCGGCATTTTCCGCGACGGATGCAGCGACAGGGC
GGTTGCCGAGGCGGCGCTGCAGCAAGGCATCAACGTTTCGGCGCTGTCGATCCAGTACCGCCACGGCACGCAGCAGAACG
GCCTCGTCATGGGCTTTGCGGCGGCCGATGCGCAGACGACCGAAAAGACGATGCAGAAGTTTCGCACCGCGCTGCAAAGC
CATTTTCGCGAATGA

Upstream 100 bases:

>100_bases
CATCGGCCAGCCCCATCTGAACCCGAACGCTTTTTTCTTGAGGGTAGGCCTCCTTTGGTTCCATTGTTAGAACCAGATTC
TATTGATTTTTGGGAACCAG

Downstream 100 bases:

>100_bases
ACAATCCAAGGTAAGAAACTGAGATTATTTGCTTTTTAAGCCAGGCCTGTGCTGGCGGGCAGTGCTAGTCCAGATCTGCC
ATCCGCGCCCGACACCGCAC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MKTSFPVDGIALDRDSPANLHRQLYVQLRGLIERRVLPSGHALPSTRVMARDLNVGRNTVIAACDQLALEGYLAIRPRRP
SVVMDLPTRSAVAEQMSVEDANPLSRRGQTMLAQPYHHGRPGMLAFHPGMPDPDNFPFNTWSKLLGRRAKFAHIDLFGTY
HVKGYPPLCEAIARYLTASRGVKCTAEQIVVTNGAQSAFDLLARLLIDDGDTVWMEEPGYYGAGSAFVSAGAKLAPLRVS
NAGWDLDPPDVVPRMIFVTPSCHHPLGITMPMEQRLNLLHMAETWRSWIIEDDYDGEYRFQGQPIPALQGIGASNRVVYV
GTFAKILFPAMRLGFMVAPKAIDHTIVSALSVSGQFAPLLTQAALADFMNEGHFTRHLRRMRRLYAERRQFFLESAQRHL
GEWLDFHATESGIQVVGIFRDGCSDRAVAEAALQQGINVSALSIQYRHGTQQNGLVMGFAAADAQTTEKTMQKFRTALQS
HFRE

Sequences:

>Translated_484_residues
MKTSFPVDGIALDRDSPANLHRQLYVQLRGLIERRVLPSGHALPSTRVMARDLNVGRNTVIAACDQLALEGYLAIRPRRP
SVVMDLPTRSAVAEQMSVEDANPLSRRGQTMLAQPYHHGRPGMLAFHPGMPDPDNFPFNTWSKLLGRRAKFAHIDLFGTY
HVKGYPPLCEAIARYLTASRGVKCTAEQIVVTNGAQSAFDLLARLLIDDGDTVWMEEPGYYGAGSAFVSAGAKLAPLRVS
NAGWDLDPPDVVPRMIFVTPSCHHPLGITMPMEQRLNLLHMAETWRSWIIEDDYDGEYRFQGQPIPALQGIGASNRVVYV
GTFAKILFPAMRLGFMVAPKAIDHTIVSALSVSGQFAPLLTQAALADFMNEGHFTRHLRRMRRLYAERRQFFLESAQRHL
GEWLDFHATESGIQVVGIFRDGCSDRAVAEAALQQGINVSALSIQYRHGTQQNGLVMGFAAADAQTTEKTMQKFRTALQS
HFRE
>Mature_484_residues
MKTSFPVDGIALDRDSPANLHRQLYVQLRGLIERRVLPSGHALPSTRVMARDLNVGRNTVIAACDQLALEGYLAIRPRRP
SVVMDLPTRSAVAEQMSVEDANPLSRRGQTMLAQPYHHGRPGMLAFHPGMPDPDNFPFNTWSKLLGRRAKFAHIDLFGTY
HVKGYPPLCEAIARYLTASRGVKCTAEQIVVTNGAQSAFDLLARLLIDDGDTVWMEEPGYYGAGSAFVSAGAKLAPLRVS
NAGWDLDPPDVVPRMIFVTPSCHHPLGITMPMEQRLNLLHMAETWRSWIIEDDYDGEYRFQGQPIPALQGIGASNRVVYV
GTFAKILFPAMRLGFMVAPKAIDHTIVSALSVSGQFAPLLTQAALADFMNEGHFTRHLRRMRRLYAERRQFFLESAQRHL
GEWLDFHATESGIQVVGIFRDGCSDRAVAEAALQQGINVSALSIQYRHGTQQNGLVMGFAAADAQTTEKTMQKFRTALQS
HFRE

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=353, Percent_Identity=21.8130311614731, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI33469970, Length=353, Percent_Identity=21.8130311614731, Blast_Score=90, Evalue=5e-18,
Organism=Escherichia coli, GI1787710, Length=414, Percent_Identity=27.536231884058, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1790797, Length=462, Percent_Identity=23.1601731601732, Blast_Score=105, Evalue=5e-24,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53794; Mature: 53794

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTSFPVDGIALDRDSPANLHRQLYVQLRGLIERRVLPSGHALPSTRVMARDLNVGRNTV
CCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCHHH
IAACDQLALEGYLAIRPRRPSVVMDLPTRSAVAEQMSVEDANPLSRRGQTMLAQPYHHGR
HHHHHHHHHCCEEEECCCCCCEEEECCCHHHHHHHHCCCCCCHHHHCCCEEEECCCCCCC
PGMLAFHPGMPDPDNFPFNTWSKLLGRRAKFAHIDLFGTYHVKGYPPLCEAIARYLTASR
CCEEEECCCCCCCCCCCCHHHHHHHCCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHHCC
GVKCTAEQIVVTNGAQSAFDLLARLLIDDGDTVWMEEPGYYGAGSAFVSAGAKLAPLRVS
CCEEEECEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHCCCEEEEEEEC
NAGWDLDPPDVVPRMIFVTPSCHHPLGITMPMEQRLNLLHMAETWRSWIIEDDYDGEYRF
CCCCCCCCHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
QGQPIPALQGIGASNRVVYVGTFAKILFPAMRLGFMVAPKAIDHTIVSALSVSGQFAPLL
CCCCCCHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHH
TQAALADFMNEGHFTRHLRRMRRLYAERRQFFLESAQRHLGEWLDFHATESGIQVVGIFR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
DGCSDRAVAEAALQQGINVSALSIQYRHGTQQNGLVMGFAAADAQTTEKTMQKFRTALQS
CCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
HFRE
HCCC
>Mature Secondary Structure
MKTSFPVDGIALDRDSPANLHRQLYVQLRGLIERRVLPSGHALPSTRVMARDLNVGRNTV
CCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCHHH
IAACDQLALEGYLAIRPRRPSVVMDLPTRSAVAEQMSVEDANPLSRRGQTMLAQPYHHGR
HHHHHHHHHCCEEEECCCCCCEEEECCCHHHHHHHHCCCCCCHHHHCCCEEEECCCCCCC
PGMLAFHPGMPDPDNFPFNTWSKLLGRRAKFAHIDLFGTYHVKGYPPLCEAIARYLTASR
CCEEEECCCCCCCCCCCCHHHHHHHCCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHHCC
GVKCTAEQIVVTNGAQSAFDLLARLLIDDGDTVWMEEPGYYGAGSAFVSAGAKLAPLRVS
CCEEEECEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHCCCEEEEEEEC
NAGWDLDPPDVVPRMIFVTPSCHHPLGITMPMEQRLNLLHMAETWRSWIIEDDYDGEYRF
CCCCCCCCHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
QGQPIPALQGIGASNRVVYVGTFAKILFPAMRLGFMVAPKAIDHTIVSALSVSGQFAPLL
CCCCCCHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHH
TQAALADFMNEGHFTRHLRRMRRLYAERRQFFLESAQRHLGEWLDFHATESGIQVVGIFR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
DGCSDRAVAEAALQQGINVSALSIQYRHGTQQNGLVMGFAAADAQTTEKTMQKFRTALQS
CCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
HFRE
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]