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The map label for this gene is ahpC [C]

Identifier: 13472213

GI number: 13472213

Start: 1977375

End: 1978043

Strand: Reverse

Name: ahpC [C]

Synonym: mll2432

Alternate gene names: 13472213

Gene position: 1978043-1977375 (Counterclockwise)

Preceding gene: 13472215

Following gene: 13472212

Centisome position: 28.11

GC content: 61.29

Gene sequence:

>669_bases
ATGTCTCTTCGTATCGCCGACACCGCGCCCGATTTCGCCGCCGAAACCACCCACGGCCCAATCAGCTTCCACGATTGGCT
GGGCAATTCATGGGGCATCCTGTTTTCTCATCCCAAGGATTTTACCCCCGTCTGCACCACTGAACTCGGTTACATGGCCA
AGCTGAAGCCCGAGTTCGACAAGCGTAACGTCAAGATCATCGGGCTTTCCGTCGATCCGGTCGAGCGTCATGCCGGATGG
GCTGATGACATTGCCGAGACCCAGGGACAGGCGCCGAATTTCCCGATGATCGGCGACCCGATGCTGGCCATTGCCAAGCT
CTACGATATGCTGCCCGCCACGGCCGGCGACAGCGCCGAGGGGCGCACGGCGGCAGACAACCAGACGGTGCGCCATGTCT
ACGTCATCGGACCCGACAAGAAGATCAAGCTGATGATCGCCTATCCGATGACCACCGGCCGGAACTTCGACGAGATCCTG
CGTGTGGTGGACTCCATGCAACTGACCGCCAAGCATCGCGTCGCCACGCCGGTGAACTGGCGGCCGGGCGACGACGTGAT
CATCGCGGGTTCGGTTTCGAACGACGAAGCCAAGGTGCTCTACCCCGATGGCTGGAAGCAGCCCAAGCCGTATATCCGCA
TCGTGCCGCAGCCTCACAGCAACGCCTGA

Upstream 100 bases:

>100_bases
CGCCGTCACAAGCGCCTGTGGGGCGGGGAACGCTGGCGGAACATAGGTTGCCTAGTCTGCACCCGTAGTCAATTCCAACC
GTCTCTCACAGGAGGATCAA

Downstream 100 bases:

>100_bases
GCCTTCTCAAAGACATCAGGCAACAGGAGGTGACAGTATGAAAACCCGTATCCTTATCCTCGGCGCCGGTTTCGGCGGGC
TCGAGCTCAGCACGTCCTTG

Product: antioxidant protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MSLRIADTAPDFAAETTHGPISFHDWLGNSWGILFSHPKDFTPVCTTELGYMAKLKPEFDKRNVKIIGLSVDPVERHAGW
ADDIAETQGQAPNFPMIGDPMLAIAKLYDMLPATAGDSAEGRTAADNQTVRHVYVIGPDKKIKLMIAYPMTTGRNFDEIL
RVVDSMQLTAKHRVATPVNWRPGDDVIIAGSVSNDEAKVLYPDGWKQPKPYIRIVPQPHSNA

Sequences:

>Translated_222_residues
MSLRIADTAPDFAAETTHGPISFHDWLGNSWGILFSHPKDFTPVCTTELGYMAKLKPEFDKRNVKIIGLSVDPVERHAGW
ADDIAETQGQAPNFPMIGDPMLAIAKLYDMLPATAGDSAEGRTAADNQTVRHVYVIGPDKKIKLMIAYPMTTGRNFDEIL
RVVDSMQLTAKHRVATPVNWRPGDDVIIAGSVSNDEAKVLYPDGWKQPKPYIRIVPQPHSNA
>Mature_221_residues
SLRIADTAPDFAAETTHGPISFHDWLGNSWGILFSHPKDFTPVCTTELGYMAKLKPEFDKRNVKIIGLSVDPVERHAGWA
DDIAETQGQAPNFPMIGDPMLAIAKLYDMLPATAGDSAEGRTAADNQTVRHVYVIGPDKKIKLMIAYPMTTGRNFDEILR
VVDSMQLTAKHRVATPVNWRPGDDVIIAGSVSNDEAKVLYPDGWKQPKPYIRIVPQPHSNA

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=225, Percent_Identity=54.2222222222222, Blast_Score=228, Evalue=4e-60,
Organism=Homo sapiens, GI4505591, Length=190, Percent_Identity=32.1052631578947, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI32455266, Length=190, Percent_Identity=32.1052631578947, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI32455264, Length=190, Percent_Identity=32.1052631578947, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI32189392, Length=189, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI5453549, Length=157, Percent_Identity=28.6624203821656, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI5802974, Length=163, Percent_Identity=27.6073619631902, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI32483377, Length=163, Percent_Identity=27.6073619631902, Blast_Score=71, Evalue=9e-13,
Organism=Escherichia coli, GI1786822, Length=155, Percent_Identity=29.6774193548387, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25153706, Length=200, Percent_Identity=43.5, Blast_Score=155, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI193204376, Length=177, Percent_Identity=28.2485875706215, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI32565831, Length=177, Percent_Identity=28.2485875706215, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17554494, Length=177, Percent_Identity=25.9887005649718, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319407, Length=216, Percent_Identity=55.0925925925926, Blast_Score=231, Evalue=7e-62,
Organism=Saccharomyces cerevisiae, GI6323613, Length=192, Percent_Identity=24.4791666666667, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24652436, Length=209, Percent_Identity=47.3684210526316, Blast_Score=200, Evalue=7e-52,
Organism=Drosophila melanogaster, GI24581278, Length=224, Percent_Identity=47.3214285714286, Blast_Score=199, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24652434, Length=209, Percent_Identity=46.4114832535885, Blast_Score=197, Evalue=4e-51,
Organism=Drosophila melanogaster, GI17975518, Length=209, Percent_Identity=46.4114832535885, Blast_Score=197, Evalue=6e-51,
Organism=Drosophila melanogaster, GI17738015, Length=189, Percent_Identity=26.4550264550265, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17157991, Length=177, Percent_Identity=27.1186440677966, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24641739, Length=177, Percent_Identity=27.1186440677966, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21357347, Length=201, Percent_Identity=26.865671641791, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24656348, Length=182, Percent_Identity=29.1208791208791, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17864676, Length=182, Percent_Identity=29.1208791208791, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 24520; Mature: 24389

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00214 FABP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRIADTAPDFAAETTHGPISFHDWLGNSWGILFSHPKDFTPVCTTELGYMAKLKPEFD
CEEEECCCCCCCCCCCCCCCEEHHHHCCCCCCEEEECCCCCCCCHHHCCCEEEECCCCCC
KRNVKIIGLSVDPVERHAGWADDIAETQGQAPNFPMIGDPMLAIAKLYDMLPATAGDSAE
CCCEEEEEEECCHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
GRTAADNQTVRHVYVIGPDKKIKLMIAYPMTTGRNFDEILRVVDSMQLTAKHRVATPVNW
CCCCCCCCEEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
RPGDDVIIAGSVSNDEAKVLYPDGWKQPKPYIRIVPQPHSNA
CCCCCEEEEECCCCCCCEEECCCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
SLRIADTAPDFAAETTHGPISFHDWLGNSWGILFSHPKDFTPVCTTELGYMAKLKPEFD
EEEECCCCCCCCCCCCCCCEEHHHHCCCCCCEEEECCCCCCCCHHHCCCEEEECCCCCC
KRNVKIIGLSVDPVERHAGWADDIAETQGQAPNFPMIGDPMLAIAKLYDMLPATAGDSAE
CCCEEEEEEECCHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
GRTAADNQTVRHVYVIGPDKKIKLMIAYPMTTGRNFDEILRVVDSMQLTAKHRVATPVNW
CCCCCCCCEEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
RPGDDVIIAGSVSNDEAKVLYPDGWKQPKPYIRIVPQPHSNA
CCCCCEEEEECCCCCCCEEECCCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA