Click here to switch to the map view.

The map label for this gene is groES

Identifier: 13472183

GI number: 13472183

Start: 1946464

End: 1946778

Strand: Direct

Name: groES

Synonym: mlr2393

Alternate gene names: 13472183

Gene position: 1946464-1946778 (Clockwise)

Preceding gene: 13472180

Following gene: 13472184

Centisome position: 27.66

GC content: 62.86

Gene sequence:

>315_bases
ATGACGTTCCGTCCATTGCATGACCGTATCCTGGTCCGCCGCATCGAAGCCGAGGAGAAGACGGCCGGCGGCATCATCAT
CCCCGATACCGCCAAGGAGAAGCCGCAGGAGGGCGAGGTGATTGCCATCGGCCCAGGCGCCCGTGACGAGAGCGGCAAGC
TCACGCCTCTCGACGTCAAGGCGGGCGATCGCATCCTGTTCGGCAAGTGGTCCGGCACTGAGATCAAGCTCAACGGCGAG
GATCTGCTGATCATGAAGGAGAGCGACGTGATGGGCGTGATCGAGCAGACCGCGACGGTCAAGAAAGCCGCCTGA

Upstream 100 bases:

>100_bases
GCGATGCCTGAAAAAGGGTCGTGGCGCCCCGCACCGGCCTGATATTGCCGATCCGGTGTGGAGGAACCTCAAAAATCTGT
TTGTCCCGAAGGAGAACGAT

Downstream 100 bases:

>100_bases
CCAAGGCTTTGATCCAACCGCATCCAATCAATGAAGCTGCCTGTTGAAGGAGTGATCCAATGGCTGCCAAGGAAGTGAAA
TTCCATTCCGACGCCCGTGA

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein 2; Protein Cpn10 2

Number of amino acids: Translated: 104; Mature: 103

Protein sequence:

>104_residues
MTFRPLHDRILVRRIEAEEKTAGGIIIPDTAKEKPQEGEVIAIGPGARDESGKLTPLDVKAGDRILFGKWSGTEIKLNGE
DLLIMKESDVMGVIEQTATVKKAA

Sequences:

>Translated_104_residues
MTFRPLHDRILVRRIEAEEKTAGGIIIPDTAKEKPQEGEVIAIGPGARDESGKLTPLDVKAGDRILFGKWSGTEIKLNGE
DLLIMKESDVMGVIEQTATVKKAA
>Mature_103_residues
TFRPLHDRILVRRIEAEEKTAGGIIIPDTAKEKPQEGEVIAIGPGARDESGKLTPLDVKAGDRILFGKWSGTEIKLNGED
LLIMKESDVMGVIEQTATVKKAA

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Homo sapiens, GI4504523, Length=90, Percent_Identity=36.6666666666667, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=45.8333333333333, Blast_Score=92, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17555568, Length=94, Percent_Identity=43.6170212765958, Blast_Score=91, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6324594, Length=91, Percent_Identity=38.4615384615385, Blast_Score=75, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356029, Length=94, Percent_Identity=44.6808510638298, Blast_Score=82, Evalue=8e-17,
Organism=Drosophila melanogaster, GI21358317, Length=93, Percent_Identity=38.7096774193548, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH102_RHILO (Q98II0)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_103750.1
- ProteinModelPortal:   Q98II0
- SMR:   Q98II0
- GeneID:   1226411
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr2393
- NMPDR:   fig|266835.1.peg.1854
- HOGENOM:   HBG703377
- OMA:   SDERTKG
- ProtClustDB:   PRK00364
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 11311; Mature: 11180

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFRPLHDRILVRRIEAEEKTAGGIIIPDTAKEKPQEGEVIAIGPGARDESGKLTPLDVK
CCCCCCCHHEEEEEECCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEC
AGDRILFGKWSGTEIKLNGEDLLIMKESDVMGVIEQTATVKKAA
CCCEEEEECCCCCEEEECCCEEEEEECCCCEEEECCCCEEECCC
>Mature Secondary Structure 
TFRPLHDRILVRRIEAEEKTAGGIIIPDTAKEKPQEGEVIAIGPGARDESGKLTPLDVK
CCCCCCHHEEEEEECCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEC
AGDRILFGKWSGTEIKLNGEDLLIMKESDVMGVIEQTATVKKAA
CCCEEEEECCCCCEEEECCCEEEEEECCCCEEEECCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968