Click here to switch to the map view.

The map label for this gene is zraS [C]

Identifier: 13472175

GI number: 13472175

Start: 1933927

End: 1935999

Strand: Reverse

Name: zraS [C]

Synonym: mll2384

Alternate gene names: 13472175

Gene position: 1935999-1933927 (Counterclockwise)

Preceding gene: 13472176

Following gene: 13472171

Centisome position: 27.52

GC content: 58.85

Gene sequence:

>2073_bases
ATGCAAAGACCATCGCGGATACGTTCGAAGAAATTGGAAATCGCTCAATTGGCCGACGGCCCGGCAAAGGCTCGCGTGCT
CGCAGTCGATGATGACGAACGCAATCTGTTGGCGATTCAAGAGGTCTTGGCCCCAATTGCGGAAATCGTCGCCGTGCGAT
CCGGCGAGGAGGCCCTGCGCTGCCTGTTGAAGCAGGATTTCGCTGTTATTTTGCTGGACGTGTTGATGCCGGGCCTCGAC
GGCTACGAGACGGCCGGACTGATCCGCCAGCGCGAACAGTCGAAGCGCACGCCTCTGATCTTCCTCACGGCCATCAACAA
GGAAGATGCCCATATGCTGCGCGGCTACGATGCGGGCGCGGTGGACTATGTGTTCAAGCCGTTCGACCCAGTCATGCTGC
GCTCCAAAGTGGCTGTATTCGTCGAGCTTCACGAAAAGACGCTCGAAATCCAGCGCAAGGCGATTGCTGAGCAAGCGTTG
CTGGCAAAGGCCCTGCAGGCCGAGAAAGAAAAGCTCGAGGCCGAGCGGTCGCTACGCAGCGCGGAGGAACGTCAGGAAGC
CATTCTTGGCTCCTTGCCCGTCTGCTTTCACGCCAGAGCAGCCGAGCCGCCCTTTGCGGCCCGCTTTGTCACCAAGGGTG
TCGAACGCTTGACGGGATTTCCACCGGAGCGACTGACGTCCGATCCGCGCTTTGGCCTGAGCCGTGTCCATCCTGATGAC
CTGCCAAGGGTGCGGGAAGCATTGCTGGCCGCAAAGGCTACAGGATCGTACACGTGCGAGTTCCGCTGGCAATGCGCTGA
TGGCAAATACCGCATCTTTCTGGACCAGGGCATCCTGTCGAAAAGTGTTGACGGTCGCCGACCCGAAATCTTGGGTACGT
TGCTCGACGTGACCGAGCGGCGTGAACTCGAAGATCAGCTTCTTCAATCGCAACGCCTCGACGCAATCGGCAAGCTCACG
GGAGGGTTGGCGCATGACTTCAACAATCTGCTTGCCGCAATACTCAGTGGACTGGGATTGCTTGAGCGGCACGCAACGCT
CGACGATCAGGCGAGACAGGTCGTTGACCTAACCCGGCGCTCGGCGAAACAAGGCGCGGAACTCGTCAGCCGCATGCTGG
CCTTTTCGCGGCGTCAGAATCTGAAGCCGGCAGCTGTCCATCTCGCGACCTTGGGCGACACGATGAACGGGTTGGTGGCT
CCGGTGCTGGGAGGGCTGATCCGCTTTGAATGGAAAATCGACAATTCCGTTTGGCTCGCACACGTCGATGTCGGCCAACT
GGAACTGGCTTTGATGAATTTGGTCTTCAATGCACGTGACGCCATGCCGTCGGGCGGAACAATTACAGTGCATGCGCAAA
ATCGGGTGATTGAAATCGCATCCGAAGATCTGCCGCCGGGCGACTATGTGGTTGTCACTGTCAAAGACACCGGTGCTGGC
ATCCCACAGGACATTCTGGCCAAGGTGGTCGAACCCTTTTTCACGACAAAGCCCGTCGGCAAGGGTACGGGCTTGGGCCT
GAGTACGGTCTACGGGTTCATAAAGCAGTCCGGCGGCTCGCTGCGCATAGACAGTGCGGTTGGTCGCGGAACTGCGATGG
AATTGTGGTTGCCCCGTTCGATCGAGCAGCGGGCGGCCGGCGATGTCGCTGAACGCGAGGCAGAGCCGATCGATGCGGGC
AAGGAACTCCCGTCGATTCTTTTGATCGACGACAGCAGCGTGTTGCGGCAACTGACCGCGCAATCACTCCAGCAACGTGG
TTTCGTTGTGACCTGCGCAGCTGGGAGCGCCGAAGCGCTGGCAATAATCGAACGGGCGCCACATGAATTCGACGTGATTG
TCACTGACTTCGCCATGCCACTCGTTTCCGGGGTGGAAGTCATTCGCTTTGCGCGCAATCTCCGTTCCGATTGGCCGGCG
ATAATCATAACCGGATACGCCGATGCGGACTCGATTGCCGATCGACCATCGGATGTCCCGCTGCTTAACAAGCCGTTCCG
CGAAAAGGATCTCATCGAGAGCATCTTCCACGTGATCGCCCACGCCAGCGCGAAGGCAATCAAGACAGGATAG

Upstream 100 bases:

>100_bases
CGATCTTTTGCTGGCGCTGCTTCGGGTCTGGATCGGACGCTCTCGGGCGAGGGTCGAGACTTCGGAAAAGCTGCTCTCGT
CAGTAAACTGAGGGTGTCCG

Downstream 100 bases:

>100_bases
CGCAGCCGATTGGAAATCGTACACGACTTCGGACTCGCCTTGCATGTGATTGCTCGGGGAAACCGCGTTGCGCTCAAGCC
CGCAAGCGTTCAACTCTTCC

Product: sensor/response regulator hybrid protein

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 690; Mature: 690

Protein sequence:

>690_residues
MQRPSRIRSKKLEIAQLADGPAKARVLAVDDDERNLLAIQEVLAPIAEIVAVRSGEEALRCLLKQDFAVILLDVLMPGLD
GYETAGLIRQREQSKRTPLIFLTAINKEDAHMLRGYDAGAVDYVFKPFDPVMLRSKVAVFVELHEKTLEIQRKAIAEQAL
LAKALQAEKEKLEAERSLRSAEERQEAILGSLPVCFHARAAEPPFAARFVTKGVERLTGFPPERLTSDPRFGLSRVHPDD
LPRVREALLAAKATGSYTCEFRWQCADGKYRIFLDQGILSKSVDGRRPEILGTLLDVTERRELEDQLLQSQRLDAIGKLT
GGLAHDFNNLLAAILSGLGLLERHATLDDQARQVVDLTRRSAKQGAELVSRMLAFSRRQNLKPAAVHLATLGDTMNGLVA
PVLGGLIRFEWKIDNSVWLAHVDVGQLELALMNLVFNARDAMPSGGTITVHAQNRVIEIASEDLPPGDYVVVTVKDTGAG
IPQDILAKVVEPFFTTKPVGKGTGLGLSTVYGFIKQSGGSLRIDSAVGRGTAMELWLPRSIEQRAAGDVAEREAEPIDAG
KELPSILLIDDSSVLRQLTAQSLQQRGFVVTCAAGSAEALAIIERAPHEFDVIVTDFAMPLVSGVEVIRFARNLRSDWPA
IIITGYADADSIADRPSDVPLLNKPFREKDLIESIFHVIAHASAKAIKTG

Sequences:

>Translated_690_residues
MQRPSRIRSKKLEIAQLADGPAKARVLAVDDDERNLLAIQEVLAPIAEIVAVRSGEEALRCLLKQDFAVILLDVLMPGLD
GYETAGLIRQREQSKRTPLIFLTAINKEDAHMLRGYDAGAVDYVFKPFDPVMLRSKVAVFVELHEKTLEIQRKAIAEQAL
LAKALQAEKEKLEAERSLRSAEERQEAILGSLPVCFHARAAEPPFAARFVTKGVERLTGFPPERLTSDPRFGLSRVHPDD
LPRVREALLAAKATGSYTCEFRWQCADGKYRIFLDQGILSKSVDGRRPEILGTLLDVTERRELEDQLLQSQRLDAIGKLT
GGLAHDFNNLLAAILSGLGLLERHATLDDQARQVVDLTRRSAKQGAELVSRMLAFSRRQNLKPAAVHLATLGDTMNGLVA
PVLGGLIRFEWKIDNSVWLAHVDVGQLELALMNLVFNARDAMPSGGTITVHAQNRVIEIASEDLPPGDYVVVTVKDTGAG
IPQDILAKVVEPFFTTKPVGKGTGLGLSTVYGFIKQSGGSLRIDSAVGRGTAMELWLPRSIEQRAAGDVAEREAEPIDAG
KELPSILLIDDSSVLRQLTAQSLQQRGFVVTCAAGSAEALAIIERAPHEFDVIVTDFAMPLVSGVEVIRFARNLRSDWPA
IIITGYADADSIADRPSDVPLLNKPFREKDLIESIFHVIAHASAKAIKTG
>Mature_690_residues
MQRPSRIRSKKLEIAQLADGPAKARVLAVDDDERNLLAIQEVLAPIAEIVAVRSGEEALRCLLKQDFAVILLDVLMPGLD
GYETAGLIRQREQSKRTPLIFLTAINKEDAHMLRGYDAGAVDYVFKPFDPVMLRSKVAVFVELHEKTLEIQRKAIAEQAL
LAKALQAEKEKLEAERSLRSAEERQEAILGSLPVCFHARAAEPPFAARFVTKGVERLTGFPPERLTSDPRFGLSRVHPDD
LPRVREALLAAKATGSYTCEFRWQCADGKYRIFLDQGILSKSVDGRRPEILGTLLDVTERRELEDQLLQSQRLDAIGKLT
GGLAHDFNNLLAAILSGLGLLERHATLDDQARQVVDLTRRSAKQGAELVSRMLAFSRRQNLKPAAVHLATLGDTMNGLVA
PVLGGLIRFEWKIDNSVWLAHVDVGQLELALMNLVFNARDAMPSGGTITVHAQNRVIEIASEDLPPGDYVVVTVKDTGAG
IPQDILAKVVEPFFTTKPVGKGTGLGLSTVYGFIKQSGGSLRIDSAVGRGTAMELWLPRSIEQRAAGDVAEREAEPIDAG
KELPSILLIDDSSVLRQLTAQSLQQRGFVVTCAAGSAEALAIIERAPHEFDVIVTDFAMPLVSGVEVIRFARNLRSDWPA
IIITGYADADSIADRPSDVPLLNKPFREKDLIESIFHVIAHASAKAIKTG

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=246, Percent_Identity=30.4878048780488, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI1788549, Length=269, Percent_Identity=26.0223048327138, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87082012, Length=130, Percent_Identity=34.6153846153846, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788713, Length=370, Percent_Identity=24.0540540540541, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI48994928, Length=434, Percent_Identity=23.5023041474654, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87081816, Length=183, Percent_Identity=27.3224043715847, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 75518; Mature: 75518

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRPSRIRSKKLEIAQLADGPAKARVLAVDDDERNLLAIQEVLAPIAEIVAVRSGEEALR
CCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
CLLKQDFAVILLDVLMPGLDGYETAGLIRQREQSKRTPLIFLTAINKEDAHMLRGYDAGA
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHCCCCCC
VDYVFKPFDPVMLRSKVAVFVELHEKTLEIQRKAIAEQALLAKALQAEKEKLEAERSLRS
HHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEERQEAILGSLPVCFHARAAEPPFAARFVTKGVERLTGFPPERLTSDPRFGLSRVHPDD
HHHHHHHHHCCCCHHEECCCCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCC
LPRVREALLAAKATGSYTCEFRWQCADGKYRIFLDQGILSKSVDGRRPEILGTLLDVTER
HHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEEECCCHHCCCCCCCHHHHHHHHHHHHH
RELEDQLLQSQRLDAIGKLTGGLAHDFNNLLAAILSGLGLLERHATLDDQARQVVDLTRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
SAKQGAELVSRMLAFSRRQNLKPAAVHLATLGDTMNGLVAPVLGGLIRFEWKIDNSVWLA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHCCCEEEEEEECCCEEEE
HVDVGQLELALMNLVFNARDAMPSGGTITVHAQNRVIEIASEDLPPGDYVVVTVKDTGAG
EECCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEECCCCCCCCEEEEEEECCCCC
IPQDILAKVVEPFFTTKPVGKGTGLGLSTVYGFIKQSGGSLRIDSAVGRGTAMELWLPRS
CCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCEEEEECCCC
IEQRAAGDVAEREAEPIDAGKELPSILLIDDSSVLRQLTAQSLQQRGFVVTCAAGSAEAL
HHHHHCCCHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCEEEEEECCCCHHH
AIIERAPHEFDVIVTDFAMPLVSGVEVIRFARNLRSDWPAIIITGYADADSIADRPSDVP
HHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHCCCCCCCC
LLNKPFREKDLIESIFHVIAHASAKAIKTG
CCCCCCCHHHHHHHHHHHHHHCCCHHCCCC
>Mature Secondary Structure
MQRPSRIRSKKLEIAQLADGPAKARVLAVDDDERNLLAIQEVLAPIAEIVAVRSGEEALR
CCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
CLLKQDFAVILLDVLMPGLDGYETAGLIRQREQSKRTPLIFLTAINKEDAHMLRGYDAGA
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHCCCCCC
VDYVFKPFDPVMLRSKVAVFVELHEKTLEIQRKAIAEQALLAKALQAEKEKLEAERSLRS
HHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEERQEAILGSLPVCFHARAAEPPFAARFVTKGVERLTGFPPERLTSDPRFGLSRVHPDD
HHHHHHHHHCCCCHHEECCCCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCC
LPRVREALLAAKATGSYTCEFRWQCADGKYRIFLDQGILSKSVDGRRPEILGTLLDVTER
HHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEEECCCHHCCCCCCCHHHHHHHHHHHHH
RELEDQLLQSQRLDAIGKLTGGLAHDFNNLLAAILSGLGLLERHATLDDQARQVVDLTRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
SAKQGAELVSRMLAFSRRQNLKPAAVHLATLGDTMNGLVAPVLGGLIRFEWKIDNSVWLA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHCCCEEEEEEECCCEEEE
HVDVGQLELALMNLVFNARDAMPSGGTITVHAQNRVIEIASEDLPPGDYVVVTVKDTGAG
EECCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEECCCCCCCCEEEEEEECCCCC
IPQDILAKVVEPFFTTKPVGKGTGLGLSTVYGFIKQSGGSLRIDSAVGRGTAMELWLPRS
CCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCEEEEECCCC
IEQRAAGDVAEREAEPIDAGKELPSILLIDDSSVLRQLTAQSLQQRGFVVTCAAGSAEAL
HHHHHCCCHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCEEEEEECCCCHHH
AIIERAPHEFDVIVTDFAMPLVSGVEVIRFARNLRSDWPAIIITGYADADSIADRPSDVP
HHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHCCCCCCCC
LLNKPFREKDLIESIFHVIAHASAKAIKTG
CCCCCCCHHHHHHHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA