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The map label for this gene is gntK [H]

Identifier: 13471644

GI number: 13471644

Start: 1404092

End: 1404574

Strand: Reverse

Name: gntK [H]

Synonym: mll1676

Alternate gene names: 13471644

Gene position: 1404574-1404092 (Counterclockwise)

Preceding gene: 13471645

Following gene: 13471641

Centisome position: 19.96

GC content: 68.32

Gene sequence:

>483_bases
ATGGGCGTCGCCGGTTGCGGCAAGTCGGCTGTCGGCATCGCGCTGGCGGCCGCGCTGGATGCCGTCTTCATCGAAGGCGA
CAGGCTGCATCCGCCGGAGAATGTGGCGCGCATGGCAAGCGGCGAGCCGCTCACCGACCAGTTGCGTGAAGGCTGGCTCG
ACGCCATCGGCGAGCGCATCGCGACGTCGATCGGCGAAGGGCAGGGCGTGGTCGCGGCCTGCTCGGCGCTCAAGCGCAGC
CATCGCGAACGCCTGCGCGGTTTTTGCCCCGATATCGTCTTCCTCTATCTGGAGATCGACCCGACGACCGCAAGGCGGCG
GGTCGCCAGCCGCAAGGGCCATTTCATGCCGGCAAGCCTGGTCGACAGCCAGTTCGCCATTCTCGAGCCGCCGGGCAGCG
ATGAGCGGGCGCTGACAATCGACGCGACGCGTCCCGTCGCCGATGCCGTTGCCGACGCGATGCGCCTGCTGGCCAATTCA
TGA

Upstream 100 bases:

>100_bases
ACCGCTTCACACTTTTCGGCATCATGCTCTAGCCGTGGACGGAGAAGCAGCGCAGGCGCCGGCGGGCGCTCCCCGCTTGA
TGCCTCTGGCCATCGTGGTG

Downstream 100 bases:

>100_bases
GCCGGTATCGCCGCCTGTCATTGGCGTCGCCCTGGGCGATCAGGGAATCTTACGATGACAAACGCCGCTCCCCAGCCGTC
GATCTAAATCTGCGAGGACA

Product: gluconokinase

Products: NA

Alternate protein names: Gluconate kinase 2 [H]

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MGVAGCGKSAVGIALAAALDAVFIEGDRLHPPENVARMASGEPLTDQLREGWLDAIGERIATSIGEGQGVVAACSALKRS
HRERLRGFCPDIVFLYLEIDPTTARRRVASRKGHFMPASLVDSQFAILEPPGSDERALTIDATRPVADAVADAMRLLANS

Sequences:

>Translated_160_residues
MGVAGCGKSAVGIALAAALDAVFIEGDRLHPPENVARMASGEPLTDQLREGWLDAIGERIATSIGEGQGVVAACSALKRS
HRERLRGFCPDIVFLYLEIDPTTARRRVASRKGHFMPASLVDSQFAILEPPGSDERALTIDATRPVADAVADAMRLLANS
>Mature_159_residues
GVAGCGKSAVGIALAAALDAVFIEGDRLHPPENVARMASGEPLTDQLREGWLDAIGERIATSIGEGQGVVAACSALKRSH
RERLRGFCPDIVFLYLEIDPTTARRRVASRKGHFMPASLVDSQFAILEPPGSDERALTIDATRPVADAVADAMRLLANS

Specific function: Gluconate utilization system GNT-I. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=176, Percent_Identity=36.9318181818182, Blast_Score=104, Evalue=4e-23,
Organism=Escherichia coli, GI87082265, Length=158, Percent_Identity=39.2405063291139, Blast_Score=123, Evalue=6e-30,
Organism=Escherichia coli, GI1790719, Length=151, Percent_Identity=39.0728476821192, Blast_Score=117, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI25146487, Length=160, Percent_Identity=44.375, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6320454, Length=140, Percent_Identity=40, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 16980; Mature: 16848

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVAGCGKSAVGIALAAALDAVFIEGDRLHPPENVARMASGEPLTDQLREGWLDAIGERI
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
ATSIGEGQGVVAACSALKRSHRERLRGFCPDIVFLYLEIDPTTARRRVASRKGHFMPASL
HHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHCCCCCCHHH
VDSQFAILEPPGSDERALTIDATRPVADAVADAMRLLANS
HCCCEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GVAGCGKSAVGIALAAALDAVFIEGDRLHPPENVARMASGEPLTDQLREGWLDAIGERI
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
ATSIGEGQGVVAACSALKRSHRERLRGFCPDIVFLYLEIDPTTARRRVASRKGHFMPASL
HHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHCCCCCCHHH
VDSQFAILEPPGSDERALTIDATRPVADAVADAMRLLANS
HCCCEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9135111; 9278503; 8655507; 11468405 [H]