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The map label for this gene is cysW [H]

Identifier: 13471638

GI number: 13471638

Start: 1399473

End: 1400357

Strand: Direct

Name: cysW [H]

Synonym: mlr1668

Alternate gene names: 13471638

Gene position: 1399473-1400357 (Clockwise)

Preceding gene: 13471637

Following gene: 13471639

Centisome position: 19.89

GC content: 62.49

Gene sequence:

>885_bases
ATGGCTGATCCCGAAATCAAATCCTACGAACCCTACCATGAGAGCCGCTCGGCGGCGGTGACCGAAAGCCGTCCCGCGCA
AGCCGTCCTGATGGCGATCGCTTTTGTCTTCCTCGGCGTCTTCCTGCTTTTGCCACTGATCATCGTCTTCCACGAGGCGC
TGGCGAAAGGCGTCAGCGCCTATACGCAGGCATTGGGCGAGCCGGACGCGCGCTCGGCCATCCGTCTGACACTGCTTGTC
GCTGCGATCTCGGTGCCGCTCAACGTCGTCTTCGGCATCTCTGCCGCCTGGGCGATCGCCAAGTTCGAGTTCAAGGGTAA
GGCGTTTCTCACCACGCTGATCGATTTGCCCTTCTCGGTCTCGCCAGTCATTTCCGGCCTGGTCTATGTGCTGCTGTTCG
GCGCGCAAGGGCTGCTCGGCGGGTGGCTGAAGGCACATGGCATCCAGATCCTGTTCGCGGTGCCCGGTATTGTGCTTGCC
ACCGTCTTCGTCACCTTCCCCTTCGTCGCCCGCGAGCTGATCCCGCTGATGCAGGAACAGGGCAATGGCGACGAGGAGGC
CGCGCTTTCGCTCGGCGCCAATGGCTGGCAGACCTTCTGGTATGTGACGCTGCCCAACGTCAAATGGGGCCTGCTCTACG
GCGTGCTGCTTTGCAACGCGCGCGCCATGGGCGAATTCGGCGCGGTGTCGGTGGTGTCGGGCCATATACGCGGTCTGACC
AACACCATGCCGCTGCATGTCGAAATCCTCTACAACGAGTACAATGCCGTCGGTGCCTTTGCCGTCGCTTCACTGCTTGC
CGGGCTGGCGCTCGTCACGCTGGTCTTGAAAACACTGCTCGAGATGCGCTACGGCGCCGAACTCGCCGCGACGCGCGGGC
ATTAG

Upstream 100 bases:

>100_bases
AACTACCCGGCGGCGACCGCGATCGCGGCGATCATGCTGGCCCTGTCGTTCGTCATGCTTCTGGTCGTCAATCTCGTTCA
GACATGGAGCCGCAAGCGCT

Downstream 100 bases:

>100_bases
AAGGTTTTGTAAATGGAAGTTCGCGTTGCCAACGTGCGCAAGGAGTTCGAGCGGTTTCCGGCGCTCCATGACGTTTCGCT
CGACATCAAGTCGGGCGAAC

Product: permease protein of sulfate ABC transporter

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MADPEIKSYEPYHESRSAAVTESRPAQAVLMAIAFVFLGVFLLLPLIIVFHEALAKGVSAYTQALGEPDARSAIRLTLLV
AAISVPLNVVFGISAAWAIAKFEFKGKAFLTTLIDLPFSVSPVISGLVYVLLFGAQGLLGGWLKAHGIQILFAVPGIVLA
TVFVTFPFVARELIPLMQEQGNGDEEAALSLGANGWQTFWYVTLPNVKWGLLYGVLLCNARAMGEFGAVSVVSGHIRGLT
NTMPLHVEILYNEYNAVGAFAVASLLAGLALVTLVLKTLLEMRYGAELAATRGH

Sequences:

>Translated_294_residues
MADPEIKSYEPYHESRSAAVTESRPAQAVLMAIAFVFLGVFLLLPLIIVFHEALAKGVSAYTQALGEPDARSAIRLTLLV
AAISVPLNVVFGISAAWAIAKFEFKGKAFLTTLIDLPFSVSPVISGLVYVLLFGAQGLLGGWLKAHGIQILFAVPGIVLA
TVFVTFPFVARELIPLMQEQGNGDEEAALSLGANGWQTFWYVTLPNVKWGLLYGVLLCNARAMGEFGAVSVVSGHIRGLT
NTMPLHVEILYNEYNAVGAFAVASLLAGLALVTLVLKTLLEMRYGAELAATRGH
>Mature_293_residues
ADPEIKSYEPYHESRSAAVTESRPAQAVLMAIAFVFLGVFLLLPLIIVFHEALAKGVSAYTQALGEPDARSAIRLTLLVA
AISVPLNVVFGISAAWAIAKFEFKGKAFLTTLIDLPFSVSPVISGLVYVLLFGAQGLLGGWLKAHGIQILFAVPGIVLAT
VFVTFPFVARELIPLMQEQGNGDEEAALSLGANGWQTFWYVTLPNVKWGLLYGVLLCNARAMGEFGAVSVVSGHIRGLTN
TMPLHVEILYNEYNAVGAFAVASLLAGLALVTLVLKTLLEMRYGAELAATRGH

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=265, Percent_Identity=52.0754716981132, Blast_Score=285, Evalue=2e-78,
Organism=Escherichia coli, GI1788764, Length=234, Percent_Identity=34.6153846153846, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786980, Length=181, Percent_Identity=34.2541436464088, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31474; Mature: 31343

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADPEIKSYEPYHESRSAAVTESRPAQAVLMAIAFVFLGVFLLLPLIIVFHEALAKGVSA
CCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTQALGEPDARSAIRLTLLVAAISVPLNVVFGISAAWAIAKFEFKGKAFLTTLIDLPFSV
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHCCCCH
SPVISGLVYVLLFGAQGLLGGWLKAHGIQILFAVPGIVLATVFVTFPFVARELIPLMQEQ
HHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GNGDEEAALSLGANGWQTFWYVTLPNVKWGLLYGVLLCNARAMGEFGAVSVVSGHIRGLT
CCCCHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHCCC
NTMPLHVEILYNEYNAVGAFAVASLLAGLALVTLVLKTLLEMRYGAELAATRGH
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCC
>Mature Secondary Structure 
ADPEIKSYEPYHESRSAAVTESRPAQAVLMAIAFVFLGVFLLLPLIIVFHEALAKGVSA
CCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTQALGEPDARSAIRLTLLVAAISVPLNVVFGISAAWAIAKFEFKGKAFLTTLIDLPFSV
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHCCCCH
SPVISGLVYVLLFGAQGLLGGWLKAHGIQILFAVPGIVLATVFVTFPFVARELIPLMQEQ
HHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GNGDEEAALSLGANGWQTFWYVTLPNVKWGLLYGVLLCNARAMGEFGAVSVVSGHIRGLT
CCCCHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHCCC
NTMPLHVEILYNEYNAVGAFAVASLLAGLALVTLVLKTLLEMRYGAELAATRGH
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]