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The map label for this gene is cysU [H]

Identifier: 13471637

GI number: 13471637

Start: 1398629

End: 1399480

Strand: Direct

Name: cysU [H]

Synonym: mlr1667

Alternate gene names: 13471637

Gene position: 1398629-1399480 (Clockwise)

Preceding gene: 13471636

Following gene: 13471638

Centisome position: 19.88

GC content: 64.32

Gene sequence:

>852_bases
ATGACCACAGCACCCGCGCATGCGGGGTGGCGATTCAGGCAGCCGAGTGTCATTCCGGGTTTCGGATTGACGCTCGGCTT
CTCGCTTGCCTACCTCACCCTCATCATCCTCATTCCGCTGTCCGGGCTGATCTGGCGCTCGGCCGCGCTCGGCTGGGCTG
ACTTCTGGGCGATTGCCAGCGACCGCCGCACGCTCAATGCGCTGGAAATCAGCTTCGGCACCGCCTTCCTCGCGGCGGCC
GTCAATGTCGTCTTCGGCACGCTGGTAGCCTGGGTGCTGGTGCGCTACCGCTTTCCCGGCCGCCGCATCGTCGATGCCAT
GGTCGACCTCCCCTTCGCCCTGCCGACGGCGGTGGCCGGCATTGCGCTCACCACGCTCTATGCGCCGAACGGCTGGATCG
GCAAATTGCTGATGCCGCTCGGCATCAAAGTTGCCTACACGCCGCTCGGCATCGTCGTGGCATTGGTCTTCATCGGCCTT
CCCTTCGTCGTGCGGACGGTGCAGCCCATCATGGAGGAGATCGACAAGGAGGTGGAGGAAGCCGCCGCCACGCTTGGCGC
CAGCCGCTTTCAGATCATCACCCGCGTGCTGTTCCCGGGCCTGGCGCCGGCCATCATCACCGGCTTTTCGCTGGCCTTTG
CGCGCGGCGTCGGCGAATACGGCTCGGTCATCTTCATCGCCGGCAACCTGCCCTACAAATCAGAGATCGCGCCGCTTTTG
ATCGTCATCCGGCTGGAGGAATACAACTACCCGGCGGCGACCGCGATCGCGGCGATCATGCTGGCCCTGTCGTTCGTCAT
GCTTCTGGTCGTCAATCTCGTTCAGACATGGAGCCGCAAGCGCTATGGCTGA

Upstream 100 bases:

>100_bases
CTACAAGCCGGCCCAGTGAGGTTCGGCAGTCGCGAAGAAGCCCGCGAATGGGCTTCTTCGGCAAAGTCTGGTTGAGTAAG
AAGGGACGATCCAGAACTCC

Downstream 100 bases:

>100_bases
TCCCGAAATCAAATCCTACGAACCCTACCATGAGAGCCGCTCGGCGGCGGTGACCGAAAGCCGTCCCGCGCAAGCCGTCC
TGATGGCGATCGCTTTTGTC

Product: permease protein of sulfate ABC transporter

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MTTAPAHAGWRFRQPSVIPGFGLTLGFSLAYLTLIILIPLSGLIWRSAALGWADFWAIASDRRTLNALEISFGTAFLAAA
VNVVFGTLVAWVLVRYRFPGRRIVDAMVDLPFALPTAVAGIALTTLYAPNGWIGKLLMPLGIKVAYTPLGIVVALVFIGL
PFVVRTVQPIMEEIDKEVEEAAATLGASRFQIITRVLFPGLAPAIITGFSLAFARGVGEYGSVIFIAGNLPYKSEIAPLL
IVIRLEEYNYPAATAIAAIMLALSFVMLLVVNLVQTWSRKRYG

Sequences:

>Translated_283_residues
MTTAPAHAGWRFRQPSVIPGFGLTLGFSLAYLTLIILIPLSGLIWRSAALGWADFWAIASDRRTLNALEISFGTAFLAAA
VNVVFGTLVAWVLVRYRFPGRRIVDAMVDLPFALPTAVAGIALTTLYAPNGWIGKLLMPLGIKVAYTPLGIVVALVFIGL
PFVVRTVQPIMEEIDKEVEEAAATLGASRFQIITRVLFPGLAPAIITGFSLAFARGVGEYGSVIFIAGNLPYKSEIAPLL
IVIRLEEYNYPAATAIAAIMLALSFVMLLVVNLVQTWSRKRYG
>Mature_282_residues
TTAPAHAGWRFRQPSVIPGFGLTLGFSLAYLTLIILIPLSGLIWRSAALGWADFWAIASDRRTLNALEISFGTAFLAAAV
NVVFGTLVAWVLVRYRFPGRRIVDAMVDLPFALPTAVAGIALTTLYAPNGWIGKLLMPLGIKVAYTPLGIVVALVFIGLP
FVVRTVQPIMEEIDKEVEEAAATLGASRFQIITRVLFPGLAPAIITGFSLAFARGVGEYGSVIFIAGNLPYKSEIAPLLI
VIRLEEYNYPAATAIAAIMLALSFVMLLVVNLVQTWSRKRYG

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0555

COG function: function code O; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=267, Percent_Identity=49.812734082397, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI87082099, Length=251, Percent_Identity=29.8804780876494, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786980, Length=220, Percent_Identity=32.7272727272727, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787368, Length=233, Percent_Identity=29.6137339055794, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786254, Length=252, Percent_Identity=28.968253968254, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1787369, Length=194, Percent_Identity=28.3505154639175, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011865
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30626; Mature: 30495

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAPAHAGWRFRQPSVIPGFGLTLGFSLAYLTLIILIPLSGLIWRSAALGWADFWAIAS
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHC
DRRTLNALEISFGTAFLAAAVNVVFGTLVAWVLVRYRFPGRRIVDAMVDLPFALPTAVAG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHH
IALTTLYAPNGWIGKLLMPLGIKVAYTPLGIVVALVFIGLPFVVRTVQPIMEEIDKEVEE
HHHHHHCCCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAATLGASRFQIITRVLFPGLAPAIITGFSLAFARGVGEYGSVIFIAGNLPYKSEIAPLL
HHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEE
IVIRLEEYNYPAATAIAAIMLALSFVMLLVVNLVQTWSRKRYG
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTAPAHAGWRFRQPSVIPGFGLTLGFSLAYLTLIILIPLSGLIWRSAALGWADFWAIAS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHC
DRRTLNALEISFGTAFLAAAVNVVFGTLVAWVLVRYRFPGRRIVDAMVDLPFALPTAVAG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHH
IALTTLYAPNGWIGKLLMPLGIKVAYTPLGIVVALVFIGLPFVVRTVQPIMEEIDKEVEE
HHHHHHCCCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAATLGASRFQIITRVLFPGLAPAIITGFSLAFARGVGEYGSVIFIAGNLPYKSEIAPLL
HHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEE
IVIRLEEYNYPAATAIAAIMLALSFVMLLVVNLVQTWSRKRYG
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2188958; 9205837; 9278503; 2188959 [H]