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The map label for this gene is hbpA [H]

Identifier: 13471630

GI number: 13471630

Start: 1378670

End: 1380325

Strand: Reverse

Name: hbpA [H]

Synonym: mll1660

Alternate gene names: 13471630

Gene position: 1380325-1378670 (Counterclockwise)

Preceding gene: 13471631

Following gene: 13471629

Centisome position: 19.62

GC content: 61.11

Gene sequence:

>1656_bases
ATGACAATCTACAAGAGTAATGGCGATCGCGTTCCGGATCACATCCTGGCCATGGCCGAAGAAGCCAAGGCAGGTAAGGT
CGATCGCCGCGAATTCCTGGCGCTCGCCAGCGTCTTCGGCGCGTCGACGGCGATGGCTTACGGCCTGCTCGGCCTTGCGG
CGCCGACCGAGGCAAGAGCCGAAGATGCCCCCAAGAAGGGCGGCATCCTGAAGGTCGCCCAGTGGATCAAGGATCCGAAG
GACCCGCGCAAGTCCGACTGGTCGGAAATCGCCAATGCCGAGCGCCAGGCGCTCGAGCCGTTGGTCAAATACACCACCGA
ATACACGTTCCGCCCCTATCTGCTTGAGTCTTGGGACGTCAACGACGATGCCACCCAGTACGTGCTGCATGTGCGCAAGG
GCGTGACCTGGCACAATGGCGATGCTTTCACTGCCGACGACGTGGTGCACAACTTCAACCGCTGGGGCGAGAAGGCCGCT
GAAGGCAATTCCATGCCCGGCCGTCTTGGCACGCTGTTCGACGACAAGACCGGCAAGCTGCGTGAAGGCGCGGTCACCAA
GGTCGACGACATGACCGTCAAGCTGTCGCTCACCAAGCCCGACATCTCGATCATTCCCGGGATTTGCGACTATGTGGCGC
TCATCGTCCACAAGTCCTTCGACGAAAAGGGCGGCGACTTCAAGGCCTGCCCGATCGGCACCGGTCCGTTCGAGCTCGTC
TCCTACGATGTCGGCCAGAAAGTGGTCTACAAGCGCCGCGCCGACAACAAGTGGTGGGACGGCGACGTCTATCTCGACGG
CATCGAGTTCATCGACTACGGCACCGATCCGGCCGCCATGGTCAGCGCTTTCGAGGCCGGCGAAGTGCATACCAATTTCG
AAACGTCGGCCGACTATGTGTCGATCCTCGACAAGATGGACCTGGTCAAGTCCGAAGTCGTCACCGCCTCGACTATCGTC
TGCCGCACCAACGTCACCCACAAGCCTTACGACAACGAGAAGGTGCGCAAGGCGCTGCAACTCGGCGTCGACAACAATGT
CGTGCTCCAGCTCGGCTACGGCAATGCCGGCTCGGTCGCCGAGAACCACCATGTCTGCTCGATCCATCCGGAATATTACG
AGCTGCCCAAGCTTACCCGCGATCCGGCCAAGGCGAAGGCGCTGATGGCGGAAGCCGGTCAGGCCGATTTCGAGCATGAA
CTGATCACCGTCGACGAGGACTGGCACAAGAACACCGGCGACGCGATCGCCGCCCAGCTGCGCGACGCAGGTATCAAGGT
GAAGCGCACCGTGCTGCCGGGCTCGACGTTCTGGAACGACTGGCTGAAGTATCCGCTGTCGATGACGAACTGGAACATGC
GTCCGCTCGGCGTTCAGGTTCTGGCGCTGGCCTACCGCACCGGTGAGGCCTGGAACGAGTGTGCCTGGTCGAACCCAGAC
TGGGATGCCAAGCTGAACGCCGCGCTTGCGGTTTCCGACGCGGCCAAGCGCAAGGAAATGATGAAGGACATCGAGCAGAT
CCTGCAGGATTCCGGCATCATCATCCAACCTTACTGGCGCAAGCTCTACAGCCACTCGGTCAAGGCGGTGCAAAACTACA
AGATGCATCCGACCTTCGAGCGCGACTACGGCAAGATCTGGCTCGACCAGGCGTGA

Upstream 100 bases:

>100_bases
GTTGCACATTCGCCAACATGTTCCCAATCCAAGCCGTCTTTGACATCACGGCCTGGATGCGGAATGTTAATCGGCGGAAA
GCCAACAATGGGAGTTAGTC

Downstream 100 bases:

>100_bases
TCAGGCCAAGCAGGAGGAAGGGGCAGTTCGCCCCTTTCTCCCTCTCTGCATGATTCCAAAACCAGAAGTCGGCGCAGCAA
AAGTTGCGGACTCCTCTGGC

Product: dipeptide binding protein component of ABC transporter

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 551; Mature: 550

Protein sequence:

>551_residues
MTIYKSNGDRVPDHILAMAEEAKAGKVDRREFLALASVFGASTAMAYGLLGLAAPTEARAEDAPKKGGILKVAQWIKDPK
DPRKSDWSEIANAERQALEPLVKYTTEYTFRPYLLESWDVNDDATQYVLHVRKGVTWHNGDAFTADDVVHNFNRWGEKAA
EGNSMPGRLGTLFDDKTGKLREGAVTKVDDMTVKLSLTKPDISIIPGICDYVALIVHKSFDEKGGDFKACPIGTGPFELV
SYDVGQKVVYKRRADNKWWDGDVYLDGIEFIDYGTDPAAMVSAFEAGEVHTNFETSADYVSILDKMDLVKSEVVTASTIV
CRTNVTHKPYDNEKVRKALQLGVDNNVVLQLGYGNAGSVAENHHVCSIHPEYYELPKLTRDPAKAKALMAEAGQADFEHE
LITVDEDWHKNTGDAIAAQLRDAGIKVKRTVLPGSTFWNDWLKYPLSMTNWNMRPLGVQVLALAYRTGEAWNECAWSNPD
WDAKLNAALAVSDAAKRKEMMKDIEQILQDSGIIIQPYWRKLYSHSVKAVQNYKMHPTFERDYGKIWLDQA

Sequences:

>Translated_551_residues
MTIYKSNGDRVPDHILAMAEEAKAGKVDRREFLALASVFGASTAMAYGLLGLAAPTEARAEDAPKKGGILKVAQWIKDPK
DPRKSDWSEIANAERQALEPLVKYTTEYTFRPYLLESWDVNDDATQYVLHVRKGVTWHNGDAFTADDVVHNFNRWGEKAA
EGNSMPGRLGTLFDDKTGKLREGAVTKVDDMTVKLSLTKPDISIIPGICDYVALIVHKSFDEKGGDFKACPIGTGPFELV
SYDVGQKVVYKRRADNKWWDGDVYLDGIEFIDYGTDPAAMVSAFEAGEVHTNFETSADYVSILDKMDLVKSEVVTASTIV
CRTNVTHKPYDNEKVRKALQLGVDNNVVLQLGYGNAGSVAENHHVCSIHPEYYELPKLTRDPAKAKALMAEAGQADFEHE
LITVDEDWHKNTGDAIAAQLRDAGIKVKRTVLPGSTFWNDWLKYPLSMTNWNMRPLGVQVLALAYRTGEAWNECAWSNPD
WDAKLNAALAVSDAAKRKEMMKDIEQILQDSGIIIQPYWRKLYSHSVKAVQNYKMHPTFERDYGKIWLDQA
>Mature_550_residues
TIYKSNGDRVPDHILAMAEEAKAGKVDRREFLALASVFGASTAMAYGLLGLAAPTEARAEDAPKKGGILKVAQWIKDPKD
PRKSDWSEIANAERQALEPLVKYTTEYTFRPYLLESWDVNDDATQYVLHVRKGVTWHNGDAFTADDVVHNFNRWGEKAAE
GNSMPGRLGTLFDDKTGKLREGAVTKVDDMTVKLSLTKPDISIIPGICDYVALIVHKSFDEKGGDFKACPIGTGPFELVS
YDVGQKVVYKRRADNKWWDGDVYLDGIEFIDYGTDPAAMVSAFEAGEVHTNFETSADYVSILDKMDLVKSEVVTASTIVC
RTNVTHKPYDNEKVRKALQLGVDNNVVLQLGYGNAGSVAENHHVCSIHPEYYELPKLTRDPAKAKALMAEAGQADFEHEL
ITVDEDWHKNTGDAIAAQLRDAGIKVKRTVLPGSTFWNDWLKYPLSMTNWNMRPLGVQVLALAYRTGEAWNECAWSNPDW
DAKLNAALAVSDAAKRKEMMKDIEQILQDSGIIIQPYWRKLYSHSVKAVQNYKMHPTFERDYGKIWLDQA

Specific function: Important role in heme acquisition or metabolism [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=455, Percent_Identity=25.4945054945055, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1787551, Length=439, Percent_Identity=26.4236902050114, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI1787052, Length=484, Percent_Identity=23.9669421487603, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1789397, Length=493, Percent_Identity=22.5152129817444, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787495, Length=521, Percent_Identity=22.2648752399232, Blast_Score=79, Evalue=9e-16,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 61650; Mature: 61519

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIYKSNGDRVPDHILAMAEEAKAGKVDRREFLALASVFGASTAMAYGLLGLAAPTEARA
CEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
EDAPKKGGILKVAQWIKDPKDPRKSDWSEIANAERQALEPLVKYTTEYTFRPYLLESWDV
CCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCC
NDDATQYVLHVRKGVTWHNGDAFTADDVVHNFNRWGEKAAEGNSMPGRLGTLFDDKTGKL
CCHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
REGAVTKVDDMTVKLSLTKPDISIIPGICDYVALIVHKSFDEKGGDFKACPIGTGPFELV
CCCCCEEECCEEEEEEECCCCCHHCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHH
SYDVGQKVVYKRRADNKWWDGDVYLDGIEFIDYGTDPAAMVSAFEAGEVHTNFETSADYV
HHHCCHHHHHHHCCCCCCCCCCEEECCEEEEECCCCHHHHHHHHHCCCCCCCCCCCHHHH
SILDKMDLVKSEVVTASTIVCRTNVTHKPYDNEKVRKALQLGVDNNVVLQLGYGNAGSVA
HHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCC
ENHHVCSIHPEYYELPKLTRDPAKAKALMAEAGQADFEHELITVDEDWHKNTGDAIAAQL
CCCCEEEECCHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHH
RDAGIKVKRTVLPGSTFWNDWLKYPLSMTNWNMRPLGVQVLALAYRTGEAWNECAWSNPD
HHCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCCCCC
WDAKLNAALAVSDAAKRKEMMKDIEQILQDSGIIIQPYWRKLYSHSVKAVQNYKMHPTFE
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCC
RDYGKIWLDQA
CCCCEEEECCC
>Mature Secondary Structure 
TIYKSNGDRVPDHILAMAEEAKAGKVDRREFLALASVFGASTAMAYGLLGLAAPTEARA
EEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
EDAPKKGGILKVAQWIKDPKDPRKSDWSEIANAERQALEPLVKYTTEYTFRPYLLESWDV
CCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCC
NDDATQYVLHVRKGVTWHNGDAFTADDVVHNFNRWGEKAAEGNSMPGRLGTLFDDKTGKL
CCHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
REGAVTKVDDMTVKLSLTKPDISIIPGICDYVALIVHKSFDEKGGDFKACPIGTGPFELV
CCCCCEEECCEEEEEEECCCCCHHCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHH
SYDVGQKVVYKRRADNKWWDGDVYLDGIEFIDYGTDPAAMVSAFEAGEVHTNFETSADYV
HHHCCHHHHHHHCCCCCCCCCCEEECCEEEEECCCCHHHHHHHHHCCCCCCCCCCCHHHH
SILDKMDLVKSEVVTASTIVCRTNVTHKPYDNEKVRKALQLGVDNNVVLQLGYGNAGSVA
HHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCC
ENHHVCSIHPEYYELPKLTRDPAKAKALMAEAGQADFEHELITVDEDWHKNTGDAIAAQL
CCCCEEEECCHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHH
RDAGIKVKRTVLPGSTFWNDWLKYPLSMTNWNMRPLGVQVLALAYRTGEAWNECAWSNPD
HHCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCCCCC
WDAKLNAALAVSDAAKRKEMMKDIEQILQDSGIIIQPYWRKLYSHSVKAVQNYKMHPTFE
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCC
RDYGKIWLDQA
CCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]